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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Deferataj 125mg Tablet DT is used to treat iron overload due to transfusional hemosiderosis (the accumulation of iron in the body due to frequent blood transfusions) or non-transfusion-dependent thalassemia (patients who do not require lifelong regular transfusions for survival). It works by binding to the extra iron and facilitates its removal from the body through faeces. In some cases, this medicine may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, and skin rashes.

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Whats That

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Composition :

DEFERASIROX-125MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Deferataj 125mg Tablet DT

Deferataj 125mg Tablet DT is used for treating chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients two years older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

The active ingredient in Deferataj 125mg Tablet DT is deferasirox, which binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

In some cases, you may experience common side effects such as diarrhoea, vomiting, nausea, abdominal pain, and skin rashes. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Avoid taking Deferataj 125mg Tablet DT if you are allergic to it. Do not use Deferataj 125mg Tablet DT without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Deferataj 125mg Tablet DT if you are pregnant or breastfeeding. Do not use Deferataj 125mg Tablet DT in more than prescribed doses or for a longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Deferataj 125mg Tablet DT to rule out any side effects.

Uses of Deferataj 125mg Tablet DT

Deferataj 125mg Tablet DT is used for treating chronic iron overload that occurs due to blood transfusions. The detailed uses of Deferataj 125mg Tablet DT are as follows:

  • Transfusional hemosiderosis: Used for treating chronic iron overload that occurs due to blood transfusions in patients two years of age and older.
  • Non-transfusion-dependent thalassemia (NTDT): Deferataj 125mg Tablet DT can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia.

Directions for Use

  • Deferataj 125mg Tablet DT should be taken on an empty stomach, at least 30 minutes before a meal.
  • Follow your doctor's instructions on the dosage and timing of this medication. However, it is suggested to take Deferataj 125mg Tablet DT at the same time each day to maintain a consistent level of medicine in your body.
  • Swallow the whole Deferataj 125mg Tablet DT with a glass of water.
  • Do not break, chew, or crush it.

Medicinal Benefits

  • Deferasirox is the active component in Deferataj 125mg Tablet DT.
  • It's a chelating agent that selectively binds to trivalent iron.
  • It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

How Deferataj 125mg Tablet DT Works

The active ingredient in Deferataj 125mg Tablet DT is deferasirox. It is a trivalent iron-selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Deferataj 125mg Tablet DT

Do not exceed the recommended dose, as it might cause an overdose. Overdose symptoms may include nausea, abdominal pain, vomiting, diarrhoea, and kidney/liver problems that might be serious. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Deferataj 125mg Tablet DT if you are allergic to Deferataj 125mg Tablet DT or its ingredients.
  • Deferataj 125mg Tablet DT is not usually recommended if you are a pregnant or lactating woman; there is not enough information to say whether it's safe.
  • It is unknown whether Deferataj 125mg Tablet DT alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.
  • Seek medical attention if the symptoms persist longer.
  • Avoid consuming alcohol along with Deferataj 125mg Tablet DT as it could lead to unpleasant side effects.
  • Should monitor elderly and paediatric patients closely for toxicity.

Diet & Lifestyle Advise

  • Choose foods high in nutrients, such as fruits, vegetables, and whole grains.
  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being.
  • Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).
  • Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol and caffeine consumption.

Habit Forming

No

Therapeutic Class

CHELATING AGENTS
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Alcohol

Caution

Consuming alcohol along with Deferataj 125mg Tablet DT is not advisable, as it may cause unpleasant side effects, or you also may become more sensitive to the effects of alcohol.

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Pregnancy

Consult your doctor

Deferataj 125mg Tablet DT is not usually recommended if you are pregnant. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks. Please consult the doctor.

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Breast Feeding

Consult your doctor

Deferataj 125mg Tablet DT is not usually recommended if you are a lactating woman. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks.

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Driving

Caution

It is not known whether Deferataj 125mg Tablet DT alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Deferataj 125mg Tablet DT should be used under the supervision of healthcare provider

Have a query?

FAQs

Deferataj 125mg Tablet DT is used to treat chronic iron overload due to blood transfusions (transfusional hemosiderosis).

Deferasirox is the active component in Deferataj 125mg Tablet DT. It is a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.

Deferataj 125mg Tablet DT is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

The extra iron due to iron overload is stored in pancreas. This damages the pancreas and it does not produce insulin properly. Insulin is required by the body to utilise sugar/glucose efficiently. As insulin is not produced properly, it affects blood sugar levels.

Yes, iron overload is the same as haemochromatosis. Hemochromatosis, or iron overload, is a condition in which your body stores too much iron.

Yes, Deferataj 125mg Tablet DT can be used in children above 2 years if prescribed by the doctor. Talk to the doctor if you have any concerns regarding this.

Deferataj 125mg Tablet DT may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India
Other Info - DE68606

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