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Synonym :
METHYLPREDNISOLONE SODIUM SUCCINATE
Composition :
METHYLPREDNISOLONE-40MG
Manufacturer/Marketer :
Pfizer Ltd
Consume Type :
PARENTERAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
MethylprednisoloneMifepristone
Critical
MethylprednisoloneVigabatrin
Critical
Drug-Drug Interactions
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MethylprednisoloneMifepristone
Critical
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
When Depo-Medrol 40 mg Injection 2 ml is taken with Mifepristone, it may decrease the levels of Depo-Medrol 40 mg Injection 2 ml, which may be less effective in treating your condition.
How to manage the interaction:
Taking Depo-Medrol 40 mg Injection 2 ml with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
When Depo-Medrol 40 mg Injection 2 ml is taken with Mifepristone, it may decrease the levels of Depo-Medrol 40 mg Injection 2 ml, which may be less effective in treating your condition.
How to manage the interaction:
Taking Depo-Medrol 40 mg Injection 2 ml with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneVigabatrin
Critical
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Co-administration of Depo-Medrol 40 mg Injection 2 ml and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.
How to manage the interaction:
Taking Depo-Medrol 40 mg Injection 2 ml with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
Co-administration of Depo-Medrol 40 mg Injection 2 ml and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.
How to manage the interaction:
Taking Depo-Medrol 40 mg Injection 2 ml with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneIohexol
Critical
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).
How to manage the interaction:
Taking Depo-Medrol 40 mg Injection 2 ml with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).
How to manage the interaction:
Taking Depo-Medrol 40 mg Injection 2 ml with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneKetoconazole
Severe
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Co-administration of Ketoconazole and Depo-Medrol 40 mg Injection 2 ml the levels of Depo-Medrol 40 mg Injection 2 ml in the blood may be greatly increased.
How to manage the interaction:
Although taking Ketoconazole and Depo-Medrol 40 mg Injection 2 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any of the symptoms such as swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts(blurred vision), irregular menstruation, excessive facial or body hair growth, abnormal body fat distribution, especially in the face, neck, back, and waist, decreased ability to fight infections, or a severe asthma attack, consult a doctor. Without consulting a doctor, never stop taking any drugs.
Co-administration of Ketoconazole and Depo-Medrol 40 mg Injection 2 ml the levels of Depo-Medrol 40 mg Injection 2 ml in the blood may be greatly increased.
How to manage the interaction:
Although taking Ketoconazole and Depo-Medrol 40 mg Injection 2 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any of the symptoms such as swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts(blurred vision), irregular menstruation, excessive facial or body hair growth, abnormal body fat distribution, especially in the face, neck, back, and waist, decreased ability to fight infections, or a severe asthma attack, consult a doctor. Without consulting a doctor, never stop taking any drugs.
MethylprednisoloneIndinavir
Severe
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Coadministration of Indinavir with Depo-Medrol 40 mg Injection 2 ml may significantly increase the blood levels of Depo-Medrol 40 mg Injection 2 ml which increases the risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Depo-Medrol 40 mg Injection 2 ml and Indinavir, but it can be taken if prescribed by a doctor. If you notice any of these signs - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thin skin, easy bruising, irregular periods, more bruises, too much facial or body hair, strange fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Coadministration of Indinavir with Depo-Medrol 40 mg Injection 2 ml may significantly increase the blood levels of Depo-Medrol 40 mg Injection 2 ml which increases the risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Depo-Medrol 40 mg Injection 2 ml and Indinavir, but it can be taken if prescribed by a doctor. If you notice any of these signs - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thin skin, easy bruising, irregular periods, more bruises, too much facial or body hair, strange fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
MethylprednisoloneClarithromycin
Severe
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Taking Clarithromycin with Depo-Medrol 40 mg Injection 2 ml together may significantly increase the blood levels of Depo-Medrol 40 mg Injection 2 ml.
How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Depo-Medrol 40 mg Injection 2 ml if prescribed by the doctor. Consult the prescriber if you experience side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without a doctor's advice.
Taking Clarithromycin with Depo-Medrol 40 mg Injection 2 ml together may significantly increase the blood levels of Depo-Medrol 40 mg Injection 2 ml.
How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Depo-Medrol 40 mg Injection 2 ml if prescribed by the doctor. Consult the prescriber if you experience side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneItraconazole
Severe
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Depo-Medrol 40 mg Injection 2 ml blood levels can rise when itraconazole and methylprednisone are used together, which may increase the risk of side effects.
How to manage the interaction:
Depo-Medrol 40 mg Injection 2 ml and itraconazole may interact, but if a doctor prescribes them, you can still use them. Swelling, high blood pressure, high blood sugar, muscle weakness, depression, acne, stretch marks, easy bruising, bone density loss, cataracts(eye problem), irregular menstruation, and excessive face or body hair growth are all signs that you need to consult a doctor. Never discontinue taking a medication without consulting a doctor.
Depo-Medrol 40 mg Injection 2 ml blood levels can rise when itraconazole and methylprednisone are used together, which may increase the risk of side effects.
How to manage the interaction:
Depo-Medrol 40 mg Injection 2 ml and itraconazole may interact, but if a doctor prescribes them, you can still use them. Swelling, high blood pressure, high blood sugar, muscle weakness, depression, acne, stretch marks, easy bruising, bone density loss, cataracts(eye problem), irregular menstruation, and excessive face or body hair growth are all signs that you need to consult a doctor. Never discontinue taking a medication without consulting a doctor.
MethylprednisoloneDesmopressin
Severe
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Co-administration of Desmopressin with Depo-Medrol 40 mg Injection 2 ml together may increase the risk of hyponatremia (low levels of salt in the blood).
How to manage the interaction:
Desmopressin and Depo-Medrol 40 mg Injection 2 ml can cause an interaction, but it can be taken if advised by a doctor. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood), Contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
Co-administration of Desmopressin with Depo-Medrol 40 mg Injection 2 ml together may increase the risk of hyponatremia (low levels of salt in the blood).
How to manage the interaction:
Desmopressin and Depo-Medrol 40 mg Injection 2 ml can cause an interaction, but it can be taken if advised by a doctor. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood), Contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneAdalimumab
Severe
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Using adalimumab together with Depo-Medrol 40 mg Injection 2 ml may increase the risk of serious infections.
How to manage the interaction:
There may be a possibility of interaction between Depo-Medrol 40 mg Injection 2 ml and Adalimumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Using adalimumab together with Depo-Medrol 40 mg Injection 2 ml may increase the risk of serious infections.
How to manage the interaction:
There may be a possibility of interaction between Depo-Medrol 40 mg Injection 2 ml and Adalimumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
MethylprednisoloneCeritinib
Severe
How does the drug interact with Depo-Medrol 40 mg Injection 2 ml:
Taking Depo-Medrol 40 mg Injection 2 ml with ceritinib may significantly increase the blood levels of Depo-Medrol 40 mg Injection 2 ml.
How to manage the interaction:
Although taking Depo-Medrol 40 mg Injection 2 ml and ceritinib together can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience swelling, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without consulting a doctor.
Taking Depo-Medrol 40 mg Injection 2 ml with ceritinib may significantly increase the blood levels of Depo-Medrol 40 mg Injection 2 ml.
How to manage the interaction:
Although taking Depo-Medrol 40 mg Injection 2 ml and ceritinib together can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience swelling, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
METHYLPREDNISOLONE-40MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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METHYLPREDNISOLONE-40MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking Depo-Medrol 40 mg Injection 2 ml with Grapefruit may increase the blood level of Depo-Medrol 40 mg Injection 2 ml. Avoid consuming Grapefruit and Grapefruit juice while taking Depo-Medrol 40 mg Injection 2 ml.
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking Depo-Medrol 40 mg Injection 2 ml with Grapefruit may increase the blood level of Depo-Medrol 40 mg Injection 2 ml. Avoid consuming Grapefruit and Grapefruit juice while taking Depo-Medrol 40 mg Injection 2 ml.
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Product Substitutes
Alcohol
Caution
No interaction was found. However, limit alcohol consumption as a precautionary measure.
Pregnancy
Caution
Inform your doctor if you are pregnant or suspect or planning pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Depo-Medrol 40 mg Injection 2 ml.
Breast Feeding
Safe if prescribed
Depo-Medrol 40 mg Injection 2 ml is considered safe to be used during breastfeeding. If you are breastfeeding, inform your doctor before receiving this injection. Your doctor will weigh the benefits and potential risks before prescribing Depo-Medrol 40 mg Injection 2 ml.
Driving
Caution
Depo-Medrol 40 mg Injection 2 ml has no or insignificant effect on one's ability to drive or operate machinery. In rare cases, Depo-Medrol 40 mg Injection 2 ml may cause blurred vision or other visual disturbances. If you experience these symptoms, do not drive or operate machinery until you are alert.
Liver
Caution
If you have a history of liver diseases/conditions or ongoing liver conditions, inform your doctor before receiving Depo-Medrol 40 mg Injection 2 ml. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.
Kidney
Caution
If you have a history of kidney diseases/conditions or ongoing kidney conditions, inform your doctor before receiving Depo-Medrol 40 mg Injection 2 ml. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.
Children
Caution
Depo-Medrol 40 mg Injection 2 ml is generally not recommended for use in children because it can delay growth and development as well as severe headaches with blurred vision or temporary visual problems. Before prescribing this medication to your child, your paediatrician may weigh the benefits and risks.
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