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  3. DETRUSITOL 2MG TABLET

DETRUSITOL 2MG TABLET, Pack of 14 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

DETRUSITOL 2MG TABLET is used for overactive bladder syndrome. It contains Tolteradone, which works by relaxing the urinary bladder muscles and prevents urgent, frequent, or uncontrolled urination. It may cause side effects such as dryness in the mouth, headache, constipation, sleepiness, dizziness, blurred vision, and dry skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

TOLTERODINE-2MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About DETRUSITOL 2MG TABLET

DETRUSITOL 2MG TABLET is used for overactive bladder syndrome (it is a condition in which the bladder contracts muscles uncontrollably and urgent need to urinate, causing frequent urination and inability to control urination).

DETRUSITOL 2MG TABLET contains tolteradone. DETRUSITOL 2MG TABLET works by relaxing the urinary bladder muscles and prevents urgent, frequent, or uncontrolled urination.

Take DETRUSITOL 2MG TABLET as prescribed by your doctor. Depending on your medical conditions, you are advised to take DETRUSITOL 2MG TABLET for as long as your doctor has prescribed it for you. You may experience dryness in the mouth, headache, constipation, sleepiness, dizziness, blurred vision, and dry skin. Most of these side effects of DETRUSITOL 2MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting DETRUSITOL 2MG TABLET, please inform your doctor if you have any allergies, glaucoma (increased pressure in the eye that may cause vision loss), urinary retention (inability to empty your bladder completely or at all), or gastric retention (slow emptying of your stomach). Do not take this DETRUSITOL 2MG TABLET if you have liver, kidney, heart problems or constipation. Immediately contact your doctor if you are pregnant and breastfeeding.

Uses of DETRUSITOL 2MG TABLET

DETRUSITOL 2MG TABLET is used in the treatment of overactive bladder syndrome. The detailed use of DETRUSITOL 2MG TABLET is as follows:<br/>• Treatment of Overactive bladder syndrome: DETRUSITOL 2MG TABLET is used to treat overactive bladder (OAB) symptoms, including urinary urgency, frequency, and incontinence, by relaxing the bladder muscle and helping to control bladder contractions.<br/>

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Directions for Use

• DETRUSITOL 2MG TABLET can be taken with or without a meal.• Take DETRUSITOL 2MG TABLET twice daily, or as recommended by your doctor.• Swallow it as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

DETRUSITOL 2MG TABLET belongs to a group of medications known as antimuscarinics. DETRUSITOL 2MG TABLET is used for overactive bladder syndrome (it is a condition in which the bladder contracts muscles uncontrollably and urgent need to urinate, causing frequent urination and inability to control urination). DETRUSITOL 2MG TABLET works by relaxing the urinary bladder muscles and prevents urgent, frequent, or uncontrolled urination.

How DETRUSITOL 2MG TABLET Works

DETRUSITOL 2MG TABLET contains tolteradone. DETRUSITOL 2MG TABLET works by relaxing the urinary bladder muscles and prevents urgent, frequent, or uncontrolled urination.

Storage

Keep DETRUSITOL 2MG TABLET out of sight and reach of children.
Side effects of Detrusitol 2mg Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

What if I have taken an overdose of DETRUSITOL 2MG TABLET

Do not take more than the prescribed dose of DETRUSITOL 2MG TABLET as it may cause overdose. The symptoms of overdose include dry mouth or confusion. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take DETRUSITOL 2MG TABLET if you are allergic to DETRUSITOL 2MG TABLET or any of its contents. Before taking DETRUSITOL 2MG TABLET, inform your doctor if you are pregnant or breastfeeding or have kidney disease, liver disease, bladder blockage, controlled narrow-angle glaucoma, or stomach or bowel problems (including constipation), or a history of heart rhythm problems (including QT prolongation), gastrointestinal disorders, and myasthenia gravis (a long-term neuromuscular disease that leads to varying degrees of skeletal muscle weakness). DETRUSITOL 2MG TABLET has lactose, so inform your doctor if you are intolerant to sugars. DETRUSITOL 2MG TABLET may cause dizziness or blurred vision. So, do not drive or operate any heavy machinery. It can increase body temperature by decreasing sweating. So, avoid hot weather or strenuous exercise as this may cause overheating, which may lead to unwanted effects.

Drug-Drug Interactions

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TolterodinePotassium chloride
Critical
TolterodinePotassium citrate
Critical

Drug-Drug Interactions

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TolterodinePotassium chloride
Critical
How does the drug interact with Detrusitol 2mg Tablet:
Taking Detrusitol 2mg Tablet and Potassium chloride together can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Detrusitol 2mg Tablet and Potassium chloride, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or less desire to eat. Do not discontinue medications without consulting a doctor.
TolterodinePotassium citrate
Critical
How does the drug interact with Detrusitol 2mg Tablet:
Taking Detrusitol 2mg Tablet together with potassium citrate can increase the harmful effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Although there is an interaction between Detrusitol 2mg Tablet and potassium citrate, it can be taken if prescribed by the doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or loss of appetite(reduced desire to eat). Do not discontinue medications without consulting a doctor.
TolterodineZonisamide
Severe
How does the drug interact with Detrusitol 2mg Tablet:
Coadministration of Detrusitol 2mg Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Although there is an interaction between Detrusitol 2mg Tablet and Zonisamide, it can be taken if a doctor has advised it. However, if you experience increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
TolterodineCarbamazepine
Severe
How does the drug interact with Detrusitol 2mg Tablet:
Taking carbamazepine and Detrusitol 2mg Tablet together may possibly reduce the blood levels of Detrusitol 2mg Tablet, which could reduce its capacity to treat the condition you have.

How to manage the interaction:
Although taking carbamazepine and Detrusitol 2mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it.
TolterodineTopiramate
Severe
How does the drug interact with Detrusitol 2mg Tablet:
Using Detrusitol 2mg Tablet with Topiramate can increase body temperature and decreased sweating.

How to manage the interaction:
Although there is an interaction between Detrusitol 2mg Tablet and Topiramate, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sleepiness, dizziness, or lightheadedness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat fresh fruits like pears, bananas, and citrus fruits, and green vegetables like beans and potatoes. 
  • Try to take cranberry juice as it helps in minimizing urinary infections. 
  • Avoid coffee, tea, and carbonated drinks which contain caffeine. 
  • Do not consume processed, fried, or spicy foods, as these can irritate your bladder. 
  • Limit alcohol intake as it can increase the risk of side effects.
  • Quit smoking and exercise regularly.

Habit Forming

No

Therapeutic Class

ANTIMUSCARINIC AGENTS

DETRUSITOL 2MG TABLET Substitute

Substitutes safety advice
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Alcohol

Unsafe

It is unsafe to consume alcohol with DETRUSITOL 2MG TABLET.

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Pregnancy

Caution

DETRUSITOL 2MG TABLET should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

Caution should be exercised; it is advisable to consult a doctor before using it.

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Driving

Unsafe

It is not safe because DETRUSITOL 2MG TABLET may cause dizziness, drowsiness, blurred vision, or other vision problems, which can affect one's ability to drive.

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Liver

Caution

DETRUSITOL 2MG TABLET to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose.

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Kidney

Caution

DETRUSITOL 2MG TABLET to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may have to adjust the dose.

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Children

Caution

The safety of the DETRUSITOL 2MG TABLET is not determined in children. Therefore, always consult with your doctor before using the DETRUSITOL 2MG TABLET.

FAQs

DETRUSITOL 2MG TABLET is used for the treatment of overactive bladder syndrome (it is a condition in which the bladder contracts muscles uncontrollably and urgent need to urinate, causing frequent urination and inability to control urination).

DETRUSITOL 2MG TABLET contains tolteradone. DETRUSITOL 2MG TABLET works by relaxing the urinary bladder muscles and prevents urgent, frequent, or uncontrolled urination.

DETRUSITOL 2MG TABLET did not relieve the symptoms of the overactive bladder when studied in children. So, its use in children is not mentioned.

It is unclear whether DETRUSITOL 2MG TABLET can cause dementia or not. However, according to some reports, when people with dementia were given DETRUSITOL 2MG TABLET, their symptoms (confusion and misunderstanding) became worse.

DETRUSITOL 2MG TABLET does not cure your condition but helps to control the symptoms of overactive bladder.

Patients who have urinary retention (unable to pass urine), have delayed emptying of stomach or blocked intestinal tract (toxic megacolon, ulcerative colitis, pyloric stenosis) or uncontrolled high pressure in the eyes (narrow-angle glaucoma).

Your symptoms may start increasing within one week of starting DETRUSITOL 2MG TABLET. After 5-8 weeks of treatment, maximum benefits may be seen. Your doctor may prescribe $n to you for a long term of up to 24 months to continue this improvement.

Inform your doctor about your detailed medical, surgical and allergy history, if you have a history of irregular heartbeats, kidney or liver problems. Also, let your doctor know if you are taking any other medicines including antidepressants, antibiotics, or any heart medicines.

Take DETRUSITOL 2MG TABLET for as long as it is prescribed by your doctor. Do not discontinue DETRUSITOL 2MG TABLET without consulting your doctor.

The side effects of DETRUSITOL 2MG TABLET include dryness in the mouth, headache, dizziness, sleepiness, constipation, or blurred vision. If these side effects persist or worsen, please consult your doctor.

DETRUSITOL 2MG TABLET contains Tolterodine as its active ingredient.

DETRUSITOL 2MG TABLET belongs to the class of drugs called antimuscarinic agents. DETRUSITOL 2MG TABLET is not a diuretic, it is a urinary antispasmodic which relaxes the urinary bladder muscles and prevents urgent, frequent, or uncontrolled urination.

No, do not stop taking DETRUSITOL 2MG TABLET on your own even if you see improvement in your symptoms as discontinuing suddenly may cause recurring symptoms or worsen your condition. Therefore, take DETRUSITOL 2MG TABLET for as long as your doctor has prescribed it, and if you experience any difficulty while taking DETRUSITOL 2MG TABLET, please consult your doctor.

No, do not crush or chew DETRUSITOL 2MG TABLET. Swallow it as whole with a glass of water. Take it as advised by your doctor.

No, discontinuing DETRUSITOL 2MG TABLET will not have any harmful effects, but overactive bladder symptoms may reoccur. If you have constipation, contact your doctor and you can stop taking DETRUSITOL 2MG TABLET if your doctor advises.

Country of origin

United Kingdom

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - DET0042

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:39 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.4282.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021228s023lbl.pdf
  3. https://www.drugs.com/mtm/tolterodine.html

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