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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Diane 35 Tablet contains Ethylestradiol and Cyproterone. It is used to treat moderate to severe acne related to androgen sensitivity and/or hirsutism (excess hair growth) in women of reproductive age. It works by blocking the production of androgens (male hormones) in the ovaries, thereby helping reduce acne and hair growth. In some cases, this medication may cause nausea, abdominal pain, headache, weight gain and mood changes.

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Manufacturer/Marketer :

Bayer Zydus Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Diane 35 Tablet

Diane 35 Tablet is used to treat moderate to severe acne related to androgen sensitivity; and/or hirsutism (excess hair growth)in women of reproductive age with PCOS (Polycystic ovary syndrome). It should be used only if your skin condition has not improved,even after topical or antibiotic treatment. Due to its contraceptive properties, it will only be prescribed for you if your doctor considers that treatment with a hormonal contraceptive is appropriate.

Diane 35 Tablet contains Ethinylestradiol and Cyproterone, which work by blocking the production of androgens (male hormones) in the ovaries. Thereby, it helps reduce acne and hair growth.

In some cases, Diane 35 Tablet may cause nausea, abdominal pain, headache, weight gain and mood changes. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to consult the doctor if the side effects persist or worsen.

Do not take Diane 35 Tablet if you are allergic to any of its components or if you are pregnant, might be pregnant or breastfeeding. Diane 35 Tablet inhibits ovulation and prevents conception; therefore, avoid using additional hormonal contraceptives whilst on treatment with Diane 35 Tablet . Keep the doctor informed about your health conditions and medications to rule out any side effects/interactions.

Uses of Diane 35 Tablet

Diane 35 Tablet is used in the treatment of acne and hirsutism (excess hair growth) in women of reproductive age with PCOS. The detailed uses of Diane 35 Tablet are as follows:
• Treatment of Hormonal Acne: Diane 35 Tablet effectively manages hormone-related acne, promoting a clearer and healthier complexion over time.
• Polycystic Ovary Syndrome (PCOS) Management: Diane 35 Tablet helps regulate menstrual cycles and alleviate symptoms associated with PCOS.
• Hair Growth Regulation: Diane 35 Tablet reduces unwanted facial and body hair in women through its anti-androgenic properties.
• Contraceptive Use: Diane 35 Tablet serves as an oral contraceptive to prevent pregnancy when used as prescribed.
• Menstrual Regulation: Diane 35 Tablet supports the regularization of menstrual cycles in women with irregular periods, improving overall menstrual health.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

Diane 35 Tablet contains Ethinylestradiol and Cyproterone used to treat signs of androgenisation in women. It is indicated in the treatment of moderate to severe acne related to androgen sensitivity and/or hirsutism (excess hair growth) in women of reproductive age. Diane 35 Tablet works by blocking the production of androgens (male hormones) in the ovaries. Thereby, it helps reduce acne and hair growth.

How Diane 35 Tablet Works

Diane 35 Tablet contains Ethinylestradiol and Cyproterone, which work by blocking the production of androgens (male hormones) in the ovaries. Thereby, it helps reduce acne and hair growth.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Diane 35 Tablet

  • Nausea
  • Abdominal pain
  • Weight gain
  • Headache
  • Mood changes
  • Breast pain and tenderness

What if I have taken an overdose of Diane 35 Tablet

Do not take more than the prescribed dose. It is unlikely that taking more than one pill will do you any harm, but you may feel sick, vomit or have some vaginal bleeding. Talk to your doctor if you have any of these symptoms.

Drug Warnings

Do not use Diane 35 Tablet if you are allergic to any of its components, if you are using another hormonal contraception, are pregnant, might be pregnant or breastfeeding, or have had breast cancer, blood circulation problems/blood clots, heart attack or stroke. Inform the doctor if you have high blood pressure/uncontrolled blood pressure, high cholesterol, migraine, severe liver disease, liver tumours, depression, diabetes, inflammation of the pancreas, chloasma (brown patches on the skin), angioedema or hepatitis. Diane 35 Tablet may increase the risk of having blood clots; seek medical attention if you notice symptoms of blood clots (migraine/long-lasting headache, changes in your eye-sight, hearing or speech, severe pain in the abdomen, severe pain or swelling in legs, breathlessness, unusual sudden coughing, severe pain and tightness in the chest which may reach the left arm, dizziness/fainting, or sudden weakness/numbness). 

Drug-Drug Interactions

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EthinylestradiolTranexamic acid
Critical
EthinylestradiolPomalidomide
Severe

Drug-Drug Interactions

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EthinylestradiolTranexamic acid
Critical
How does the drug interact with Diane 35 Tablet:
Taking Diane 35 Tablet with Tranexamic acid may increase the risk of blood clot formation.

How to manage the interaction:
Taking Diane 35 Tablet with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
EthinylestradiolPomalidomide
Severe
How does the drug interact with Diane 35 Tablet:
Pomalidomide can cause serious blood clots, and taking it with Ethinyl estradiol may enhance the risk.

How to manage the interaction:
Although there is a possible interaction between Pomalidomide and Diane 35 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
EthinylestradiolGriseofulvin
Severe
How does the drug interact with Diane 35 Tablet:
Taking ethinyl estradiol with griseofulvin may reduce blood levels and the effects of ethinyl estradiol.

How to manage the interaction:
Although taking Diane 35 Tablet and Griseofulvin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you use hormone replacement therapy (ethinyl estradiol) for menopause, inform a doctor if your symptoms are no longer controlled or if you deal with unusual bleeding. Do not stop using any medications without a doctor's advice.
EthinylestradiolRifampicin
Severe
How does the drug interact with Diane 35 Tablet:
Taking Diane 35 Tablet with rifampicin can decrease the blood levels of Diane 35 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Rifampicin and Diane 35 Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medicine without consulting a doctor.
EthinylestradiolLetrozole
Severe
How does the drug interact with Diane 35 Tablet:
When taken together ethinyl estradiol may interfere with letrozole's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Letrozole and Diane 35 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
EthinylestradiolPhenytoin
Severe
How does the drug interact with Diane 35 Tablet:
Phenytoin may lower ethinyl estradiol levels in the blood and its effects. You may be more likely to experience breakthrough bleeding and unexpected pregnancy if you use low-dose oral contraceptives.

How to manage the interaction:
Although taking Phenytoin and Diane 35 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you are on hormone replacement therapy for menopause, inform a doctor if your symptoms are no longer being controlled or if you are experiencing abnormal bleeding. Do not stop using any medications without a doctor's advice.
EthinylestradiolAnastrozole
Severe
How does the drug interact with Diane 35 Tablet:
Diane 35 Tablet may interfere with anastrozole's function and make it less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Anastrozole and Diane 35 Tablet, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EthinylestradiolDabrafenib
Severe
How does the drug interact with Diane 35 Tablet:
When coupled with Dabrafenib, the blood level of Diane 35 Tablet can be reduced.

How to manage the interaction:
There may be a possibility of interaction between Dabrafenib and Diane 35 Tablet, but it can be taken if prescribed by a doctor. If you are taking hormone replacement therapy for menopause, you should notify your doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not discontinue any medications without consulting a doctor.
EthinylestradiolAmprenavir
Severe
How does the drug interact with Diane 35 Tablet:
Taking Diane 35 Tablet and Amprenavir together may make amprenavir less effective.

How to manage the interaction:
Co-administration of Diane 35 Tablet with Amprenavir can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EthinylestradiolExemestane
Severe
How does the drug interact with Diane 35 Tablet:
When used with Diane 35 Tablet, the effectiveness of Exemestane might be reduced.

How to manage the interaction:
Although taking Exemestane and Diane 35 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid processed food, milk and dairy products.
  • Always wash off your makeup before sleeping. Avoid going to bed with makeup on.
  • Exercise regularly and eat healthy food.
  • Avoid smoking and alcohol consumption.
  • Protect your skin from sun damage by using sunscreen.
  • Drink plenty of water.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Diane 35 Tablet Substitute

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Alcohol

Consult your doctor

It is not known whether Diane 35 Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Diane 35 Tablet is not recommended during pregnancy. Please consult the doctor if you are pregnant or think you may be pregnant.

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Breast Feeding

Unsafe

Diane 35 Tablet is not recommended during lactation. Please consult the doctor if you are breastfeeding.

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Driving

Safe if prescribed

Diane 35 Tablet is unlikely to affect your ability to drive.

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Liver

Caution

Diane 35 Tablet may not be recommended for patients with severe liver disease. Please consult the doctor if you have liver problems.

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Kidney

Consult your doctor

Please consult the doctor if you have kidney problems.

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Children

Caution

Diane 35 Tablet is not recommended for children. It is only indicated after menarche.

FAQs

Diane 35 Tablet is used to treat moderate to severe symptoms of PCOS like acne related to androgen sensitivity and/or hirsutism (excess hair growth) in women of reproductive age.

Diane 35 Tablet works by blocking the production of androgens (male hormones) in the ovaries. Â

Diane 35 Tablet is also a hormonal contraceptive; it should not be used in combination with other hormonal contraceptives, as this will expose the patient to an excessive dose of hormones and is not necessary for effective contraception.

Diane 35 Tablet does not protect against sexually transmitted diseases like HIV or Chlamydia. Only condoms can help do this.

Avoid using sunbeds or sunlamps and prolonged sunbathing whilst on treatment with Diane 35 Tablet as it might increase the chance of chloasma (patchy discolouration of the skin).

Diane 35 Tablet is a combination medicine used to treat acne and hirsutism (excess hair growth) in women of reproductive age with PCOS.

Diane 35 Tablet should be swallowed as a whole with water; do not crush or chew it. The dose will be determined by the doctor based on your condition.

If you miss a dose of Diane 35 Tablet , take it within the next 12 hours. If it has been more than 12 hours, skip the missed dose and take the next dose at the scheduled time.

Repeat the dose if you have vomited within 3-4 hours of taking Diane 35 Tablet . If it has been more than 4 hours, take the next dose at the scheduled time.

Diane 35 Tablet also works as a contraceptive as it inhibits ovulation and prevents conception. Avoid using additional hormonal contraceptives whilst on treatment with Diane 35 Tablet .

Diane 35 Tablet may cause nausea, abdominal pain, headache, weight gain and mood changes. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to consult the doctor if the side effects persist or worsen.

Diane 35 Tablet starts working within a few weeks and you may notice improvement in 3-4 weeks.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.
Other Info - DIA0016

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