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  1. Home
  2. Medicine

  3. Dicomef Tablet

Dicomef Tablet, Pack of 1 Tablet
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Synonym :

DICYCLOMINE HYDROCHLORIDE+MEFENAMIC ACID

Composition :

DICYCLOMINE-10MG + MEFENAMIC ACID-250MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dicomef Tablet

Dicomef Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Abdominal (tummy) pain occurs between the chest and pelvic region (below the belly button and leg).

Dicomef Tablet contains Dicyclomine and Mefenamic acid, which work by relieving contractions associated with the smooth muscles of the abdomen and blocking the chemical messengers that cause pain.

In some cases, Dicomef Tablet may cause side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Most of these side effects do not require medical attention and resolve over time. However, talk to your doctor if you experience these side effects persistently.

Do not take Dicomef Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Dicomef Tablet

Dicomef Tablet is used in the treatment of abdominal pain, dysmenorrhea (period pain), and colicky pain. The detailed uses of Dicomef Tablet are as follows:

  • Menstrual Pain Relief: Dicomef Tablet is used to relieve menstrual cramps (dysmenorrhea) by relaxing the uterine muscles, reducing pain and discomfort during periods.
  • Abdominal Pain Treatment: Dicomef Tablet helps to relieve abdominal pain and cramps caused by digestive issues by relaxing intestinal muscles and reducing spasms.
  • Colicky pain: Dicomef Tablet treats colicky pain by relaxing muscles and reducing inflammation and pain.
  • Management of Muscle Spasms: Dicomef Tablet helps relieve muscle spasms, providing comfort and relaxation to affected areas, particularly in the gastrointestinal tract.

Have a query?

Directions for Use

  • Take Dicomef Tablet with food to avoid any stomach upset.
  • It is advised to take Dicomef Tablet once daily, or as directed by your doctor.
  • Swallow Dicomef Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Dicomef Tablet is a combination medicine used to relieve abdominal pain, period pain (dysmenorrhea), and colicky pain.
  • It contains Dicyclomine and Mefenamic Acid, which work together to reduce pain and discomfort effectively.
  • Dicyclomine is an antispasmodic that relaxes the smooth muscles of the gastrointestinal tract, reducing painful contractions.
  • Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) that blocks the effects of prostaglandins, decreasing mild to moderate pain and inflammation.
  • It helps in relieving dysmenorrhea by reducing uterine contractions and associated discomfort.
  • It provides relief from spasmodic or cramping pain in the abdomen caused by gastrointestinal disturbances.
  • The dual action of muscle relaxation and anti-inflammatory effect ensures faster and more effective pain relief.

How Dicomef Tablet Works

Dicomef Tablet is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, Dicomef Tablet helps in relieving pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dicomef Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.

What if I have taken an overdose of Dicomef Tablet

An overdose of Dicomef Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Dicomef Tablet if you are allergic to any of its contents, if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers.
  • Inform your doctor if you have/had asthma, glaucoma, myasthenia gravis, high blood pressure, inflammatory bowel disease, paralytic ileus, intestinal atony, heart, kidney, or liver problems.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Dicomef Tablet may cause dizziness and drowsiness, so drive only if you are alert.
  • This medicine should not be given to children as safety has not been established.
  • Avoid consuming alcohol with Dicomef Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding.
  • Stop taking Dicomef Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.
  • Let your doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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DicyclominePotassium citrate
Critical
DicyclominePramlintide
Critical

Drug-Drug Interactions

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DicyclominePotassium citrate
Critical
How does the drug interact with Dicomef Tablet:
Taking Dicomef Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Dicomef Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DicyclominePramlintide
Critical
How does the drug interact with Dicomef Tablet:
Co-administration of Pramlintide with Dicomef Tablet can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Dicomef Tablet with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium chloride
Critical
How does the drug interact with Dicomef Tablet:
Co-administration of Dicomef Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Dicomef Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Dicomef Tablet:
Coadministration of Dicomef Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Dicomef Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Dicomef Tablet:
Co-administration of Dicomef Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Dicomef Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
DicyclomineTopiramate
Severe
How does the drug interact with Dicomef Tablet:
Co-administration of Dicomef Tablet with Topiramate may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use Dicomef Tablet and Topiramate together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. Drink plenty of fluids during warm weather and when exercising and contact a doctor if you have decreased sweating or a fever. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue the medication without consulting a doctor.
DicyclomineZonisamide
Severe
How does the drug interact with Dicomef Tablet:
Co-administration of Dicomef Tablet with Zonisamide may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use Dicomef Tablet and Zonisamide together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue any medication without consulting a doctor.
DicyclomineSecretin
Severe
How does the drug interact with Dicomef Tablet:
Co-administration of Secretin human with Dicomef Tablet may decrease the therapeutic efficacy of Secretin human.

How to manage the interaction:
Taking Dicomef Tablet with Secretin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
Mefenamic acidApixaban
Severe
How does the drug interact with Dicomef Tablet:
Dicomef Tablet and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Dicomef Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without first consulting your doctor, never stop taking any medications.
Mefenamic acidLithium
Severe
How does the drug interact with Dicomef Tablet:
Co-administration of Dicomef Tablet with Lithium can increase Lithium levels in the body.

How to manage the interaction:
Taking Dicomef Tablet with Lithium together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst, and/or increased urination, contact a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Massages can be helpful in relieving spasms.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANTISPASMODICS

Dicomef Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Dicomef Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended to breastfeed while taking Dicomef Tablet. Consult your doctor before taking Dicomef Tablet if you are breastfeeding.

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Driving

Caution

Dicomef Tablet may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Unsafe

Dicomef Tablet should not be used in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Dicomef Tablet is not recommended for children as safety and effectiveness have not been established.

FAQs

Dicomef Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain.

Dicomef Tablet contains Dicyclomine and Mefenamic acid. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

Diarrhoea might be a side-effect of Dicomef Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

Dicomef Tablet is used to treat colicky pain. Colic is a pain that is usually intestinal or urinary in nature that comes and goes and intensifies and eases gradually.

Dry mouth could be a side effect of Dicomef Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Dicomef Tablet should not be taken for more than 7days. Do not take Dicomef Tablet for longer durations, as it might increase the risk of heart problems and stomach bleeding.

Dicomef Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Dicomef Tablet only as prescribed, and do not overdose.

No, Dicomef Tablet may not cause infertility. Consult the doctor if you have any concerns.

Yes, it is safe to use Dicomef Tablet during periods if prescribed by the doctor. It helps relieve period cramps.

Dicomef Tablet may prolong prothrombin time (blood test to measure blood clotting time). Therefore, frequent monitoring of prothrombin time is advised while taking this medication.

Dicomef Tablet starts working within an hour.

Do not take Dicomef Tablet on an empty stomach. Take Dicomef Tablet with meals or immediately after meals to prevent stomach upset.

No, Dicomef Tablet is recommended for headaches and toothache. It is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain.

Yes, Dicomef Tablet can be taken with food or immediately after food.

No, Dicomef Tablet does not stop menstruation. It does not affect the menstrual bleeding or the duration of periods. It only helps relieve menstrual cramps.

Dicomef Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Dicomef Tablet may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

Yes, Dicomef Tablet is a painkiller. It contains Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicomef Tablet helps relieve abdominal pain, colicky pain, and period pains.

Yes, Dicomef Tablet is safe if taken in the dose and duration prescribed by the doctor.

Dicomef Tablet is not recommended for children as safety and effectiveness were not established.

Dicomef Tablet should be used during pregnancy only if prescribed by the doctor. Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

Dicomef Tablet may cause side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Talk to your doctor if these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Grapple Life Sciences Private Limited, Scf 1025, 1St & 2nd Floor, Motor Market, Manimajra, Chandigarh 160101, India
Other Info - DI92913

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Author Details

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Written By

Santoshini Reddy G

M Pharmacy

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Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Sep 29, 2025 | 11:21 AM IST

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Reference

  1. https://bluecrosslabs.com/wp-content/uploads/2021/01/MEFTAL-SPAS_DS_Tablets.pdf
  2. https://vibcare.co.in/dicyclomine-hydrochloride-mefenamic-acid-tablets/
  3. https://www.drugs.com/mtm/dicyclomine.html
  4. https://www.drugs.com/cdi/mefenamic-acid.html
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