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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dixin 0.25 mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. It contains Digoxin, which works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DIGOXIN-0.25MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Dixin 0.25 mg Tablet

Dixin 0.25 mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which your heart beats irregularly, too fast or too slow.

Dixin 0.25 mg Tablet contains digoxin, i.e. cardiac glycosides that help to increase the output force of the heart and reduce the rate of heart contractions. Dixin 0.25 mg Tablet works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

Take Dixin 0.25 mg Tablet as prescribed. Your doctor will recommend how often you take Dixin 0.25 mg Tablet based on your medical condition. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Most of these side effects of Dixin 0.25 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Dixin 0.25 mg Tablet or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Regular blood tests are recommended by your doctor while taking Dixin 0.25 mg Tablet to monitor the amount of Dixin 0.25 mg Tablet in the bloodstream as its toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (inability to absorb minerals from food) or any lung or kidney disease, please inform your doctor before taking Dixin 0.25 mg Tablet so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Dixin 0.25 mg Tablet has a very narrow therapeutic index. It means small differences in the dose of drugs in the body may lead to life-threatening conditions or serious side effects. This makes its use limited and requires close monitoring by doctors, such as regular electrocardiogram (ECG). So, try not to self-medicate and suggest Dixin 0.25 mg Tablet to others.

Uses of Dixin 0.25 mg Tablet

Dixin 0.25 mg Tablet used in the treatment of irregular heartbeats and the Prevention of heart failure. The detailed uses of Dixin 0.25 mg Tablet are as follows:
• Treatment of Arrhythmias: Dixin 0.25 mg Tablet is used to treat certain types of irregular heartbeats, such as atrial fibrillation and atrial flutter, by slowing the heart rate and increasing the strength of heart contractions.
• Manage Heart Failure: Dixin 0.25 mg Tablet helps to manage heart failure by strengthening heart contractions, improving heart function, and alleviating symptoms.

Directions for Use

• Dixin 0.25 mg Tablet can be taken with or without food. Avoid taking meals high in fibre, as they may reduce the absorption of the medication. • It is usually taken once daily at the same time each day. However, your doctor will determine the dosage and timing of Dixin 0.25 mg Tablet based on your age, body weight, and kidney function. • Swallow Dixin 0.25 mg Tablet as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

Dixin 0.25 mg Tablet is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. Dixin 0.25 mg Tablet increases the force with which the heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, it slows down the rate at which the heart beats and makes the heart rate normal. Dixin 0.25 mg Tablet improves heart failure symptoms, such as exercise capacity, and reduces the number of hospitalisations.

How Dixin 0.25 mg Tablet Works

Dixin 0.25 mg Tablet contains digoxin, i.e. cardiac glycosides that help to increase the output force of the heart and reduce the rate of heart contractions. Dixin 0.25 mg Tablet works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Therefore, it enables the heart to pump blood efficiently around the body and slows down the rate at which the heart beats.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Dixin 0.25 mg Tablet

Do not take more than the prescribed dose of Dixin 0.25 mg Tablet as it may cause an overdose. The symptoms of overdose include loss of appetite, vomiting, nausea and feeling tired. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Dixin 0.25 mg Tablet or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Avoid the intake of alcohol with Dixin 0.25 mg Tablet as it may increase the risk of drowsiness. Dixin 0.25 mg Tablet may cause vision problems in some people. Make sure you are not affected before driving. Regular blood tests are recommended by your doctor while taking Dixin 0.25 mg Tablet to monitor the amount of digoxin in blood as digoxin toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Dixin 0.25 mg Tablet so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Dixin 0.25 mg Tablet has a narrow therapeutic index, which makes its use limited and requires close monitoring as a small change in dose or blood concentration may lead to severe adverse effects, and overdose may lead to life-threatening reactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Dixin 0.25 mg Tablet and Famotidine may increase the level or effect of Dixin 0.25 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25 mg Tablet and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Calcium gluconate with Dixin 0.25 mg Tablet may affect heart rhythm.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Dixin 0.25 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of irregular heartbeat, blurred vision, chest tightness, nausea, and seizures. Do not discontinue the medication without consulting a doctor.
DigoxinSaquinavir
Severe
How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Dixin 0.25 mg Tablet and Saquinavir may increase the risk of severe irregular heart rhythm.

How to manage the interaction:
If you are supposed to take Dixin 0.25 mg Tablet and Saquinavir together, a doctor may adjust the dose or monitor more frequently to safely use both medications. However, if you develop lightheadedness, fainting, sudden dizziness, nausea, vomiting, loss of appetite, slow pulse, vision disturbances, or irregular heartbeat during treatment with these medications. Contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Dixin 0.25 mg Tablet and Lapatinib may increase the blood levels and effects of Dixin 0.25 mg Tablet.

How to manage the interaction:
If you are supposed to take Dixin 0.25 mg Tablet and Lapatinib together, a doctor may adjust the dose or monitor more frequently to safely use both medications. If you experience diarrhea, nausea, loss of appetite, vomiting, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, contact a doctor as these may be signs and symptoms of excessive Dixin 0.25 mg Tablet levels. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25 mg Tablet:
Coadministration of Dixin 0.25 mg Tablet and Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25 mg Tablet and Atazanavir, you can take these medicines together if prescribed by a doctor. However, if you develop fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
DigoxinNadolol
Severe
How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Dixin 0.25 mg Tablet and Nadolol may slow down the heart rate and lead to increased side effects.

How to manage the interaction:
If you are supposed to take Dixin 0.25 mg Tablet and Nadolol together, a doctor may adjust the dose to safely use both medications. However, if you experience decreased appetite, nausea, vomiting, confusion, diarrhea, seizures, visual changes, overtiredness, irregular heartbeats, and abnormally fast or slow heartbeats, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Clarithromycin with Dixin 0.25 mg Tablet may increase the blood levels and effects of Dixin 0.25 mg Tablet.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Dixin 0.25 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of excessive Dixin 0.25 mg Tablet levels such as diarrhea, nausea, loss of appetite, vomiting, visual disturbances, and an abnormally fast or slow or uneven heartbeat. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Dixin 0.25 mg Tablet and Ceritinib may slow down the heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Dixin 0.25 mg Tablet and ceritinib, it can be taken together if prescribed by a doctor. However, if you experience fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
DigoxinTelaprevir
Severe
How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Dixin 0.25 mg Tablet with Telaprevir may increase the blood levels and effects of Dixin 0.25 mg Tablet.

How to manage the interaction:
Although taking Telaprevir and Dixin 0.25 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive Dixin 0.25 mg Tablet levels. Do not stop using any medications without a doctor's advice.
DigoxinBretylium tosilate
Severe
How does the drug interact with Dixin 0.25 mg Tablet:
Co-administration of Dixin 0.25 mg Tablet and Bretylium tosilate may increase the effect of Dixin 0.25 mg Tablet.

How to manage the interaction:
Although taking Bretylium tosilate and Dixin 0.25 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling sick, throwing up, having seizures, feeling tired, or noticing your heart beating too fast or too slow, it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Dixin 0.25 mg Tablet with Grapefruit and Grapefruit juice may increase the side effects of Dixin 0.25 mg Tablet. Consuming Grapefruit and grapefruit juice should be avoided while taking Dixin 0.25 mg Tablet.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimise eating processed foods, as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do regular exercise as it helps to lower blood pressure and keeps blood vessels and the heart in good condition.
  • Quit smoking as smoking increases blood pressure and heart rate.
  • Eat a balanced and healthy diet which includes plenty of vegetables, fruits, and low-fat or fat-free products.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dixin 0.25 mg Tablet as it may increase drowsiness and reduce the amount of Dixin 0.25 mg Tablet in blood, leading to abnormal heart function.

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Pregnancy

Caution

Tablet: It is a Category C pregnancy drug and is to be given to pregnant women only if it is needed and prescribed by a doctor.

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Breast Feeding

Safe if prescribed

Tablet: It is safe for breastfeeding mothers if prescribed by a doctor.

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Driving

Caution

Dixin 0.25 mg Tablet may cause dizziness, yellow or blurred vision in some people. So, make sure you are not affected before driving or operating machinery.

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Liver

Safe if prescribed

Dixin 0.25 mg Tablet is considered safe for use if you have liver conditions. However, if you have concerns, consult your doctor before taking Dixin 0.25 mg Tablet .

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Kidney

Caution

Dixin 0.25 mg Tablet is excreted through the kidneys. Hence, if you have kidney problems, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Caution

Paediatric solution is to be used in children in doses as prescribed by a child specialist.

Have a query?

FAQs

Dixin 0.25 mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. It works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

It may take several weeks for Dixin 0.25 mg Tablet to show its effect. You are recommended to continue taking Dixin 0.25 mg Tablet for as long as your doctor prescribes it, and do not stop taking Dixin 0.25 mg Tablet suddenly, as it may worsen your heart problems. However, if you experience any difficulty while taking Dixin 0.25 mg Tablet , please consult your doctor.

Yes, Dixin 0.25 mg Tablet may cause diarrhoea as a side effect. However, it is not necessary for everyone taking Dixin 0.25 mg Tablet to experience this side effect. You are recommended to drink plenty of fluids to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsens, please consult your doctor.

Yes, Dixin 0.25 mg Tablet may cause yellow or blurred vision in some people. Therefore, exercise caution before driving or operating machinery.

No, you can eat normally. However, a balanced and healthy diet is advised for effective results.

You are not recommended to take more than the prescribed dose of Dixin 0.25 mg Tablet as it may cause Dixin 0.25 mg Tablet toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances (more than usual yellow-green). However, if you experience any of these symptoms while taking Dixin 0.25 mg Tablet , please consult a doctor immediately.

No, you are not recommended to take amiodarone with Dixin 0.25 mg Tablet as co-administration of these two medicines may increase the levels of Dixin 0.25 mg Tablet in the blood resulting in Dixin 0.25 mg Tablet toxicity. However, please consult a doctor before taking other medicines with Dixin 0.25 mg Tablet so that the dose may be adjusted appropriately.

You are recommended to avoid taking Dixin 0.25 mg Tablet if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (an extra electrical pathway causes a fast heartbeat).

Dixin 0.25 mg Tablet contains digoxin (a cardiac glycoside) that works directly on the heart muscle and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

The common side effects of Dixin 0.25 mg Tablet include diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat, and skin rash. If these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DIX0005

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