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  3. Domzole Tablet 10's

Domzole Tablet 10's, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Domzole Tablet is used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. It contains Omeprazole and Domperidone, which works by reducing acid production and increasing the movements and contractions of stomach muscles. In some cases, you may experience certain common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

DOMPERIDONE-10MG + OMEPRAZOLE-20MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Domzole Tablet

Domzole Tablet belongs to a group of medicines called gastrointestinal agents used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.

Domzole Tablet is a combination of two drugs, namely: Omeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Domzole Tablet helps in treating acidity.

Take Domzole Tablet 30-60 minutes prior to food. You are advised to take Domzole Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. Consult your doctor before taking Domzole Tablet if you are pregnant or breastfeeding. Domzole Tablet may cause sleepiness, so drive only if you are alert. Domzole Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Domzole Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Domzole Tablet

Treatment of Gastro-oesophageal reflux disease, peptic ulcers and Zollinger-Ellison syndrome.

Directions for Use

• Domzole Tablet should be taken before meals, about 15-30 minutes before breakfast or dinner.• It is usually taken twice daily or as prescribed by your doctor.• Swallow Domzole Tablet as a whole with a glass of water.• Do not crush or chew this medication

Medicinal Benefits

Domzole Tablet belongs to a group of medicines called gastrointestinal agents used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Domzole Tablet is a combination of two drugs, namely: Omeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Domzole Tablet helps in treating acidity.

How Domzole Tablet Works

Domzole Tablet is a combination of two drugs, namely: Omeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Domzole Tablet helps in treating acidity.

Storage

Keep Domzole Tablet out of reach and sight of children.

What if I have taken an overdose of Domzole Tablet

Do not take more than the prescribed dose of Domzole Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Domzole Tablet if you are allergic to any of its contents; if you are taking nelfinavir (anti-HIV); if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking Domzole Tablet if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. Talk to your doctor before taking Domzole Tablet if you have osteoporosis as Domzole Tablet may increase the risk of bone fractures on long-term treatment. Consult your doctor before taking Domzole Tablet if you are pregnant or breastfeeding. Domzole Tablet may cause sleepiness, so drive only if you are alert. Domzole Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Domzole Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid.

Diet & Lifestyle Advise

  • Eat smaller meals more often.

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

  • Maintain a healthy weight by regular exercising.

  • Avoid lying down after eating as it causes acid reflux.

  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.

  • Practise relaxation techniques and avoid stress by doing yoga or meditation.

  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 

  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Domzole Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Domzole Tablet . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking Domzole Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Domzole Tablet may pass into breast milk. Consult your doctor before taking Domzole Tablet ; your doctor will decide whether Domzole Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Domzole Tablet may cause sleepiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Domzole Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Domzole Tablet if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Domzole Tablet should not be given to children as the safety and effectiveness were not established.

Have a query?

FAQs

Domzole Tablet is used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome.

Domzole Tablet contains Omeprazole and Domperidone. Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Domzole Tablet helps in treating acidity.

Diarrhoea might be a side-effect of Domzole Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Dry mouth could be a side-effect of Domzole Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Domzole Tablet contains domperidone which helps in treating nausea and vomiting. However, Domzole Tablet is used to treat acidity. Please consult your doctor, he/she may prescribe you an alternate medicine for treating nausea and vomiting.

Do not take Domzole Tablet for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Domzole Tablet for 14days.

Domzole Tablet is usually safe and well-tolerated, with minimal side effects that are typically mild and temporary. To get the most out of this medication, be sure to follow healthy habits and take Domzole Tablet exactly as directed by your doctor. This way, you can enjoy the benefits of this medication while minimizing any potential side effects.

The contraindications of Domzole Tablet should be used cautiously and under medical supervision. Certain health conditions, medications, or situations may interact with this medication. It's essential to consult a healthcare professional for personalized advice and treatment. They will help determine the appropriate use and ensure safe administration.

Take Domzole Tablet as directed by your healthcare professional. Typically, it's best to take it before meals, about 15-30 minutes before breakfast, or at bedtime if prescribed twice daily. This helps reduce symptoms like nausea and vomiting. However, always follow your healthcare provider's specific instructions for your needs.

Domzole Tablet may rarely cause abnormal heartbeat, especially in people with pre-existing heart conditions. However, by following your doctor's advice on taking medication, maintaining healthy lifestyle habits, and attending regular check-ups, you can minimize the risks and ensure safe treatment.

Store Domzole Tablet in a cool, dry place away from sunlight. Keep it out of reach and sight of children.

Take Domzole Tablet exactly as your doctor advises. Swallow it whole with water without chewing or crushing it. Follow the prescribed dose and schedule, and don't exceed the recommended duration. If you need more clarification, consult your doctor.

Consult your doctor before taking Domzole Tablet if you have liver problems. Your doctor may adjust the dose or monitor you closely, as domperidone and omeprazole can affect liver function. It's essential to follow their advice to ensure safe treatment.

Common side effects of Domzole Tablet may include dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Domzole Tablet can interact with other medications, so it's essential to consult your doctor before taking any other medicines. Do not club any other medications with Domzole Tablet unless advised by your doctor. Your doctor will check for potential interactions and only advise additional medications if necessary. This will help avoid any harmful interactions and ensure safe treatment.

Domzole Tablet is a combination medication that contains two active ingredients: Omeprazole, a Proton Pump Inhibitor, and Domperidone, a Dopamine Antagonist.

GERD (Gastroesophageal Reflux Disease) is a condition in which stomach acid flows back into the food pipe, causing heartburn, a sour or bitter taste, and difficulty swallowing. This acid reflux irritates the oesophagus, leading to uncomfortable symptoms.

No, it's not recommended to take Domzole Tablet on your own without consulting a doctor. This medication is prescription-only and requires a doctor's supervision to ensure safe and effective treatment. Your doctor will assess your condition and medical history to determine the appropriate dosage and duration of treatment.

You should take Domzole Tablet for as long as your doctor recommends, which is usually based on your medical condition and response to treatment. Always follow their advice and do not exceed the recommended treatment period without consulting your doctor.

Avoid drinking alcohol while taking Domzole Tablet , as it may worsen side effects like drowsiness and dizziness and reduce the medication's effectiveness. To ensure safe treatment, it's best to avoid alcohol or consult your doctor for guidance.

No, unless recommended by your doctor. Consult your doctor before taking Domzole Tablet if you are pregnant or breastfeeding, as it may not be suitable for you. Your doctor will assess the risks and benefits and guide you on the safest treatment options for you and your baby.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - DOM0053

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:39 AM IST

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Reference

  1. https://vibcare.co.in/omeprazole-domperidone/
  2. https://www.medicines.org.uk/emc/files/pil.3511.pdf
  3. https://www.medicines.org.uk/emc/files/pil.556.pdf
  4. https://www.drugs.com/omeprazole.html

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