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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Don-1 Tablet is used to treat schizophrenia. It is also used alone or in combination with other medicines to treat mania or mixed episodes (mania and depression) in adults and children above 10 years with bipolar disorder. It is also used to treat behavioural problems in children aged 5 to 16 years with autism. It contains Risperidone, which works by blocking the effects of chemical messengers in the brain (i.e. dopamine and serotonin). Thus, it helps in improving mood, behaviour and thoughts. It elevates the symptoms of the disease and prevents them from coming back. In some cases, you may experience certain common side effects, such as sleepiness, vomiting, constipation, abdominal pain, nausea, dizziness, dry mouth, and fatigue.

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Composition :

RISPERIDONE-1MG

Manufacturer/Marketer :

Crescent Therapeutics Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Don-1 Tablet

Don-1 Tablet is used to treat schizophrenia. It is also used alone or in combination with other medicines to treat mania or mixed episodes (mania and depression) in adults and children above 10 years with bipolar disorder. Don-1 Tablet is also used to treat behavioural problems in children aged 5 to 16 years with autism.

Don-1 Tablet contains 'Risperidone' that works by blocking the effects of chemical messengers in the brain (i.e. dopamine and serotonin). Thus, it helps in improving mood, behaviour and thoughts. Don-1 Tablet elevates the symptoms of the disease and prevents them from coming back. 

Take Don-1 Tablet as prescribed by the doctor. In some cases, you may experience certain common side effects, such as sleepiness, vomiting, constipation, abdominal pain, nausea, dizziness, dry mouth, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Don-1 Tablet . Don-1 Tablet may cause dizziness, so do not drive or operate machinery unless you are alert. Avoid consuming alcohol along with Don-1 Tablet as it could lead to increased dizziness. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Don-1 Tablet

Treatment of Schizophrenia, Bipolar disorder, Behavioural problems in autistic children.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule. Orally disintegrating tablet: Place the orally disintegrating tablet on the tongue and allow it to dissolve. Do not chew or crush it.Syrup/Suspension/Drops: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Don-1 Tablet belongs to the group of medicines called antipsychotics used to treat schizophrenia. It is also used alone or in combination with other medicines to treat mania or mixed episodes (mania and depression) in adults and children above 10 years with bipolar disorder. Don-1 Tablet is also used to treat behavioural problems such as irritability, aggression, self-injury, and mood changes in children aged 5 to 16 years with autism. Don-1 Tablet works by blocking the effects of chemical messengers in the brain (i.e. dopamine and serotonin). Thus, it helps in improving mood, behaviour and thoughts. Don-1 Tablet elevates the symptoms of the disease and prevents them from coming back. 

How Don-1 Tablet Works

Don-1 Tablet contains 'Risperidone' that works by blocking the effects of chemical messengers in the brain (i.e. dopamine and serotonin). Thus, it helps in improving mood, behaviour and thoughts. Don-1 Tablet elevates the symptoms of the disease and prevents them from coming back.

Storage

Store in a cool and dry place away from sunlight
Side effects of Don-1 Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Don-1 Tablet

Do not take more than the prescribed dose of Don-1 Tablet as it may cause overdose. The symptoms of overdose include muscle stiffness, seizures (fits), drowsiness, fast/pounding/irregular heartbeat and unusual movements of face or body that cannot be controlled. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Don-1 Tablet if you are allergic to any of its contents. Inform your doctor if you have diabetes, high blood pressure, heart problems, low white blood cell count, seizures, breast cancer, low bone mineral density, Parkinson's disease, dehydration, phenylketonuria (accumulation of amino acid-phenylalanine in the body), liver or kidney problems. Rise slowly from sitting or lying position as Don-1 Tablet may cause orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Don-1 Tablet . 

Drug-Drug Interactions

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RisperidoneZiprasidone
Critical
RisperidonePramipexole
Critical

Drug-Drug Interactions

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RisperidoneZiprasidone
Critical
How does the drug interact with Don-1 Tablet:
Co-administration of Don-1 Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Don-1 Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RisperidonePramipexole
Critical
How does the drug interact with Don-1 Tablet:
Taking Don-1 Tablet with Pramipexole may reduce the effectiveness of Pramipexole.

How to manage the interaction:
Taking Don-1 Tablet with Pramipexole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, and lightheadedness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneCisapride
Critical
How does the drug interact with Don-1 Tablet:
When Don-1 Tablet is taken with Cisapride, it can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking cisapride together with Don-1 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
RisperidoneMetoclopramide
Critical
How does the drug interact with Don-1 Tablet:
Co-administration of Metoclopramide with Don-1 Tablet can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Don-1 Tablet with Metoclopramide is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
RisperidoneSparfloxacin
Critical
How does the drug interact with Don-1 Tablet:
Coadministration of Don-1 Tablet with sparfloxacin can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Sparfloxacin with Don-1 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneCeritinib
Severe
How does the drug interact with Don-1 Tablet:
Combining Don-1 Tablet with Ceritinib can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Co-administration of Ceritinib with Don-1 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
RisperidonePhenobarbital
Severe
How does the drug interact with Don-1 Tablet:
Taking Don-1 Tablet with phenobarbital may significantly reduce the blood levels of Don-1 Tablet.

How to manage the interaction:
Although taking phenobarbital and Don-1 Tablet together can possibly result in an interaction, but can be taken if your doctor has prescribed it. In case you experience any unusual side effects, consult a doctor.Do not stop using any medications without a doctor's advice.
RisperidonePethidine
Severe
How does the drug interact with Don-1 Tablet:
Combining Meperidine with Don-1 Tablet can increase the brain related side effects.

How to manage the interaction:
Co-administration of Pethidine with Don-1 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination. Do not discontinue any medications without a consulting a doctor.
RisperidoneMoxifloxacin
Severe
How does the drug interact with Don-1 Tablet:
Using moxifloxacin together with Don-1 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Don-1 Tablet with Moxifloxacin can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without a doctor's advice.
RisperidoneVandetanib
Severe
How does the drug interact with Don-1 Tablet:
Taking Don-1 Tablet with Vandetanib can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Co-administration of Don-1 Tablet with Vandetanib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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RISPERIDONE-1MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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RISPERIDONE-1MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Tea

How to manage the interaction:
Consumption of tea while on the treatment with Don-1 Tablet can lead to increase in side effects. Limit or avoid the consumption of tea during Don-1 Tablet treatment.

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Don-1 Tablet Substitute

Substitutes safety advice
  • Risdone Liquid 60 ml

    by Others

    2.17per tablet
  • Sizodon Oral Solution 60 ml

    by Others

    2.21per tablet
  • Sizodon 1 Tablet 10's

    by Others

    3.02per tablet
  • Risnia Syrup 60 ml

    by Others

    2.23per tablet
  • Risdone-1 Tablet 10's

    by Others

    2.61per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Don-1 Tablet as it may cause increased dizziness. Don-1 Tablet may also increase the effects of alcohol.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Don-1 Tablet may pass into the breastmilk, so it is not safe to breastfeed while taking Don-1 Tablet . Consult your doctor if you have any concerns.

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Driving

Unsafe

Don-1 Tablet may cause tiredness, dizziness and sleepiness. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Don-1 Tablet should be given to children only if prescribed by the doctor. The safety and effectiveness of Don-1 Tablet in children below 13 years with schizophrenia, below 10 years with bipolar disorder, and below 5 years with autistic disorder have not been established.

Have a query?

FAQs

Don-1 Tablet is used to treat schizophrenia. It is also used alone or in combination with other medicines to treat mania or mixed episodes (mania and depression) in adults and children above 10 years with bipolar disorder. Additionally, it is used to treat behavioural problems in children aged 5 to 16 years with autism.

Don-1 Tablet works by balancing the chemical messengers called neurotransmitter and blocking the effect of dopamine and serotonin located in the brain, thereby helps in improving mood, behaviour and thoughts.

Don-1 Tablet may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Don-1 Tablet . Diabetes patients should consult a doctor before taking Don-1 Tablet .

Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Orthostatic hypotension could be a side-effect of Don-1 Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better.

Taking Don-1 Tablet along with blood pressure-lowering medicines may cause low blood pressure. Therefore, consult your doctor if you are taking anti-hypertensives (drugs used to treat high blood pressure).

Don-1 Tablet may cause weight gain. Therefore, avoid excessive eating and follow a healthy diet. Consult your doctor if you have any concerns.

No, Don-1 Tablet is not a habit-forming drug.

Elderly patients are more likely to have age-related liver, kidney, or heart problems, and patients receiving risperidone may require caution and dosage adjustments.

It can be used, but it should be used only if prescribed the doctor.

Country of origin

INDIA

Manufacturer/Marketer address

SCO-58, 59, Sector-17D Chandigarh-160017
Other Info - DON0009

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