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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Duo-Cytra 200Ml Solution is a combination medicine used in the treatment of Kidney stones and renal tubular acidosis. This medicine works by increasing the urinary pH, potassium, magnesium, and citric acid levels; thus preventing the crystallization, growth, and accumulation of stone-forming salts. It helps provide relief from a burning sensation during urination. Common side effects include abdominal discomfort, diarrhoea, nausea, and vomiting.

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Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Duo-Cytra 200Ml Solution

Duo-Cytra 200Ml Solution is indicated for the treatment of renal tubular acidosis and kidney stones. It also helps provide relief from the burning sensation during urination. Kidney stones are small, hard deposits made up of calcium, phosphate, and other minerals/acid salts that stick together in concentrated urine. Renal tubular acidosis is a condition in which the kidneys fail to excrete acids into the urine. This causes the blood to remain too acidic.

Duo-Cytra 200Ml Solution is a combination of three drugs: Magnesium citrate, Potassium citrate, and Pyridoxine hydrochloride. Duo-Cytra 200Ml Solution raises the urinary pH, potassium, magnesium, and citric acid levels; this prevents the crystallization, growth, and accumulation of stone-forming salts.

Take Duo-Cytra 200Ml Solution as prescribed. You are advised to take Duo-Cytra 200Ml Solution for as long as your doctor has recommended it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as abdominal discomfort, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Duo-Cytra 200Ml Solution if you are pregnant or breastfeeding. Duo-Cytra 200Ml Solution is not recommended for children as safety and effectiveness have not been established. Duo-Cytra 200Ml Solution is not recommended for patients with renal insufficiency as it might increase the risk for the development of hyperkalemia (high potassium levels) and soft tissue calcification. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Duo-Cytra 200Ml Solution

Duo-Cytra 200Ml Solution is used in the treatment of Kidney stones, renal tubular acidosis. The detailed uses of Duo-Cytra 200Ml Solution are as follows:

  • Kidney Stone Prevention: By lowering the concentration of chemicals that cause kidney stones in the urine, Duo-Cytra 200Ml Solution is frequently used to help dissolve and prevent kidney stones from forming.
  • Health of the Urinary Tract: By boosting urine production and aiding in the removal of contaminants and toxins that might lead to infections, the medication supports urinary tract health.
  • Pain Relief: By lessening discomfort during urination and lowering urinary tract spasms, it may offer pain relief from urinary stones.
  • Supportive Therapy: To improve general urinary health and lower the risk of kidney stone recurrence, Duo-Cytra 200Ml Solution can be used in conjunction with other kidney stone treatments.

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Directions for Use

  • Duo-Cytra 200Ml Solution can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Duo-Cytra 200Ml Solution as a whole with a glass of water.
  • Do not chew, crush or break it.

Key Benefits

Duo-Cytra 200Ml Solution is a combination of three drugs: Magnesium citrate, Potassium citrate, and Pyridoxine hydrochloride. Duo-Cytra 200Ml Solution is indicated for the treatment of renal tubular acidosis and kidney stones, preventing the recurrence of calcium oxalate nephrolithiasis (calcium oxalate stones) and uric acid lithiasis (uric acid stones) with or without calcium stones. It also helps relieve the burning sensation during urination. Duo-Cytra 200Ml Solution raises the urinary ph, potassium, magnesium, and citric acid levels; this prevents the crystallisation, growth, and accumulation of stone-forming salts.

How Duo-Cytra 200Ml Solution Works

Duo-Cytra 200Ml Solution is a combination of three drugs: Magnesium citrate, Potassium citrate, and Pyridoxine hydrochloride. Duo-Cytra 200Ml Solution raises the urinary pH, potassium, magnesium, and citric acid levels; this prevents the crystallization, growth, and accumulation of stone-forming salts.

Storage

Store in a cool and dry place away from sunlight
Side effects of Duo-Cytra Oral Solution 200 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Duo-Cytra 200Ml Solution

Avoid exceeding the recommended dose as it might cause an overdose. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Duo-Cytra 200Ml Solution if you are allergic to any of its contents; if you have hyperkalemia (high levels of potassium), chronic renal failure, uncontrolled diabetes mellitus, adrenal insufficiency, acute dehydration, oesophageal compression, delayed gastric emptying, intestinal obstruction, peptic ulcers, urinary tract infection, or renal insufficiency. Inform your doctor if you have hyperkalemia or gastrointestinal lesions. If you experience severe vomiting, gastrointestinal bleeding, or abdominal pain, stop taking Duo-Cytra 200Ml Solution and consult a doctor immediately. Duo-Cytra 200Ml Solution is not recommended for children as safety and effectiveness have not been established. Consult your doctor before taking Duo-Cytra 200Ml Solution if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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Potassium citrateClozapine
Critical
Potassium citratePromazine
Critical

Drug-Drug Interactions

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Potassium citrateClozapine
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Clozapine and Duo-Cytra Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Co-administration of Duo-Cytra Oral Solution 200 ml with Clozapine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citratePromazine
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Promazine and Duo-Cytra Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Duo-Cytra Oral Solution 200 ml with Promazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateOlanzapine
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Olanzapine with Duo-Cytra Oral Solution 200 ml can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Olanzapine and Duo-Cytra Oral Solution 200 ml is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Potassium citrateImipramine
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Imipramine and Duo-Cytra Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Duo-Cytra Oral Solution 200 ml and Imipramine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateOrphenadrine (citrate)
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Orphenadrine and Duo-Cytra Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Orphenadrine (citrate) with Duo-Cytra Oral Solution 200 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateChlorpheniramine
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Chlorpheniramine and Duo-Cytra Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Chlorpheniramine with Duo-Cytra Oral Solution 200 ml is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateMesoridazine
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Mesoridazine and Duo-Cytra Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Duo-Cytra Oral Solution 200 ml with Mesoridazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateTrihexyphenidyl
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Co-administration of trihexyphenidyl with Duo-Cytra Oral Solution 200 ml may increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking trihexyphenidyl with Duo-Cytra Oral Solution 200 ml is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Potassium citrateOxybutynin
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Coadministration of Oxybutynin and Duo-Cytra Oral Solution 200 ml can increase the risk of developing stomach ulcers or bleeding.

How to manage the interaction:
Taking Oxybutynin with Duo-Cytra Oral Solution 200 ml is generally avoided as it may lead to an interaction, it can be taken if prescribed by the doctor. Consult the doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medications without a doctor's advice.
Potassium citrateTriprolidine
Critical
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Triprolidine and Duo-Cytra Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Triprolidine with Duo-Cytra Oral Solution 200 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids as they help in flushing out excess minerals.
  • Limit salt intake. High amounts of salt can increase the risk of kidney stones.
  • Maintain a healthy weight by exercising regularly.
  • Avoid foods rich in oxalates, such as spinach, nuts, okra, dates, avocado, hot chocolate, cocoa, baked potatoes, French fries, and cereals, as they might increase the risk of oxalate stones.
  • Try maintaining optimum calcium levels in the body, as too little or too much calcium can lead to kidney stones.

Habit Forming

No

Therapeutic Class

[RENAL AND GENITOURINARY AGENT]
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Alcohol

Caution

It is not known if alcohol interacts with Duo-Cytra 200Ml Solution. Please consult a doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Duo-Cytra 200Ml Solution; your doctor will decide whether breastfeeding mothers can take Duo-Cytra 200Ml Solution or not.

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Driving

Safe if prescribed

Duo-Cytra 200Ml Solution is unlikely to affect your ability to drive. However, you are advised to drive only if you are alert.

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Liver

Caution

Limited information is available regarding the usage of Duo-Cytra 200Ml Solution in patients with liver impairment. Please consult your doctor if you have liver problems before taking Duo-Cytra 200Ml Solution.

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Kidney

Unsafe

Duo-Cytra 200Ml Solution might cause soft tissue calcification and hyperkalaemia in patients with renal insufficiency. Please consult your doctor if you have kidney disease before taking Duo-Cytra 200Ml Solution.

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Children

Unsafe

The safety and effectiveness of Duo-Cytra 200Ml Solution in children have not been established.

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Heart

Please inform your doctor if you have heart problems before taking Duo-Cytra 200Ml Solution, as it may cause increased potassium levels, gastrointestinal discomfort, nausea, and changes in heart rhythm, which can be risky for individuals with cardiovascular conditions.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before taking Duo-Cytra 200Ml Solution, as it may cause nausea, diarrhea, abdominal discomfort, electrolyte imbalance, and changes in heart rhythm, which can be more severe in older adults and increase the risk of dehydration, confusion, or cardiac complications.

FAQs

Duo-Cytra 200Ml Solution is indicated for treating renal tubular acidosis and kidney stones. It also helps relieve the burning sensation during urination.

Duo-Cytra 200Ml Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation of stone-forming salts.

Do not discontinue Duo-Cytra 200Ml Solution without consulting your doctor. To treat your condition effectually, continue taking Duo-Cytra 200Ml Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Duo-Cytra 200Ml Solution.

Avoid taking Duo-Cytra 200Ml Solution if you have peptic ulcers, as Duo-Cytra 200Ml Solution has ulcerogenic potential, which could lead to further ulceration. Consult your doctor if you have any concerns.

Diarrhoea might be a side-effect of Duo-Cytra 200Ml Solution. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Consult a doctor before taking Duo-Cytra 200Ml Solution if you have an active urinary tract infection as Duo-Cytra 200Ml Solution increases the urinary pH, which might promote further bacterial growth.

People should not take Duo-Cytra 200Ml Solution with certain conditions, including high potassium levels, chronic renal failure, uncontrolled diabetes, adrenal insufficiency, acute dehydration, oesophagal compression, delayed gastric emptying, intestinal obstruction, peptic ulcers, urinary tract infections, and renal insufficiency. Additionally, it is not recommended for children. If you have any of these conditions, inform your doctor before prescribing this medication.

You can take Duo-Cytra 200Ml Solution only if your doctor prescribes it. Inform your doctor if you are already pregnant or planning to become pregnant. Your doctor will carefully consider the potential risks and benefits before prescribing it.

While taking Duo-Cytra 200Ml Solution, avoid foods high in potassium, like bananas, oranges, potatoes, spinach, and tomatoes. Too much potassium can be dangerous. Also, limit foods high in oxalates, like nuts, chocolate, and tea, to help prevent kidney stones. It's best to consult a dietitian for personalized dietary advice and suggestions.

Before starting treatment with Duo-Cytra 200Ml Solution, inform your doctor if you're allergic to any of its components or have certain medical conditions, such as hyperkalemia, chronic renal failure, uncontrolled diabetes mellitus, adrenal insufficiency, acute dehydration, oesophagal compression, delayed gastric emptying, intestinal obstruction, peptic ulcers, urinary tract infection, or renal insufficiency. Additionally, let your doctor know if you are pregnant or planning to become pregnant and breastfeeding. This will help avoid negative consequences and ensure optimal benefits.

While taking Duo-Cytra 200Ml Solution, avoid certain medications to prevent interactions. These include antibiotics like tetracyclines and fluoroquinolones, bisphosphonates like Fosamax and Actonel, ACE inhibitors like Lisinopril, diuretics like furosemide, and proton pump inhibitors like omeprazole. Please note that this is not an exhaustive list. Inform your doctor about all medications, including over-the-counter drugs and supplements, to ensure safe usage. Your doctor will provide complete guidance.

The common side effects of Duo-Cytra 200Ml Solution may include abdominal discomfort, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
Other Info - DUO0166

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