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  3. Duphaston 5 mg Tablet 10's

Duphaston 5 mg Tablet 10's, Pack of 10 IndiaS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Duphaston 5 mg Tablet is used in the treatment of disorders like dysmenorrhea, endometriosis, infertility, irregular menstrual cycles, and premenstrual syndrome that are linked to progesterone deficiency. It can be used in conjunction with estrogen for hormone replacement therapy or in the treatment of dysfunctional bleeding or secondary amenorrhea. It contains Dydrogesterone, which is a female hormone that controls women's ovulation and menstruation. It causes secretive changes in the uterus's endometrium lining, promotes the breast's development, relaxes the uterus, blocks the maturation and release of the follicle, and retains pregnancy. It may cause side effects such as breast tenderness, swelling in other parts of the body, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding.

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Composition :

DYDROGESTERONE-5MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Duphaston 5 mg Tablet

Duphaston 5 mg Tablet is used in the treatment of female infertility and premenstrual syndrome, which are linked to progesterone deficiency. Infertility is the inability to conceive within 12 months. Premenstrual syndrome comprises signs and symptoms like mood swings, tender breasts, food cravings, fatigue, irritability, and depression. It occurs during certain days of the menstrual period in females, generally just before their menses. It is also used for conditions like dysmenorrhea, endometriosis, infertility, and irregular menstrual cycles

Duphaston 5 mg Tablet contains dydrogesterone, a female hormone that controls women's ovulation and menstruation. Duphaston 5 mg Tablet causes changes in the uterus's endometrium lining and blocks the maturation and release of the follicle, and retains pregnancy.

Not everyone who is taking Duphaston 5 mg Tablet will get these side effects. While using this medicine, you may sometimes have breast tenderness, swelling in other parts of the body, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding. Most of these side effects of Duphaston 5 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Duphaston 5 mg Tablet as advised. Your doctor will advise you on your dose and how often you need to take this medication based on your medical condition. You can take Duphaston 5 mg Tablet with or without food. However, it is advised to take Duphaston 5 mg Tablet with food to avoid stomach upset. It is advised not to take more than the recommended dose of Duphaston 5 mg Tablet . Do not chew, crush, or break the medicine. Try not to stop taking this medicine on your own

Inform your physician if you are allergic to Duphaston 5 mg Tablet . Using Duphaston 5 mg Tablet may increase the risk of blood clots. Inform your doctor if you have had breast cancer, unusual bleeding in the vagina, liver/kidney disease, or any other health problems before starting the treatment. If you are taking any other medicine or are allergic to any medication, please inform your doctor. Avoid smoking and alcohol to prevent any unpleasant side effects. Duphaston 5 mg Tablet should not be used if you have heart disease or dementia because this medicine may increase your risk of developing these conditions.

Uses of Duphaston 5 mg Tablet

Duphaston 5 mg Tablet is used in the treatment of infertility, prevention of miscarriages, dysfunctional uterine bleeding, irregular menses cycle, and dysmenorrhoea (painful periods). The detailed uses of Duphaston 5 mg Tablet are as follows:
• Treatment of Menstrual Disorders: Duphaston 5 mg Tablet is frequently prescribed to regulate irregular menstrual cycles and manage conditions like heavy menstrual bleeding (menorrhagia). It helps restore normal menstrual function effectively.
• Support in Early Pregnancy: Duphaston 5 mg Tablet is often used to support early pregnancy for women with a history of recurrent miscarriages. By providing progesterone, it plays a vital role in maintaining a healthy pregnancy.
•Treatment of Endometriosis: This medication is valuable in managing endometriosis, a condition where tissue similar to the uterine lining grows outside of it. Duphaston 5 mg Tablet helps reduce pain and restore hormonal balance.
• Management of Hormonal Imbalance: Duphaston 5 mg Tablet is recommended for women experiencing hormonal imbalances, including those linked to PMS. It helps relieve symptoms caused by excessive estrogen levels.
• Adjunct Treatment in Infertility: In cases of infertility related to progesterone deficiency, Duphaston 5 mg Tablet may be prescribed as an adjunct treatment. It helps in the preparation of the uterine lining for implantation, increasing the likelihood of conception.

Directions for Use

  • Duphaston 5 mg Tablet can be taken with or without food. However, if it causes stomach upset, take it with food. 
  • It is recommended to take Duphaston 5 mg Tablet once daily or as advised by your doctor. 
  • Swallow Duphaston 5 mg Tablet as a whole with a glass of water. 
  • Do not crush, chew, or break it. 
  • Do not take Duphaston 5 mg Tablet if it reaches the expiry date. 

Medicinal Benefits

  • Duphaston 5 mg Tablet is a female hormone that regulates ovulation and menstruation in women. It helps maintain a healthy womb lining during the pregnancy stage.
  • Duphaston 5 mg Tablet helps initiate the menses cycle (periods) in women who have not yet reached menopause. Besides this, it prevents overgrowth of the uterus in postmenopausal women who take estrogen as hormone replacement therapy (HRT).
  • Duphaston 5 mg Tablet is used to regulate the uterine lining in postmenopausal women receiving estrogens who have not had their uterus removed through surgery. It also helps treat amenorrhea (cessation or irregular menses cycle for more than three months).
  • It is sometimes given in combination with estrogens as part of menopausal replacement therapy. Off-label use of Duphaston 5 mg Tablet helps in reducing the risk of preterm birth.

How Duphaston 5 mg Tablet Works

Duphaston 5 mg Tablet is a female hormone that controls women's ovulation and menstruation. Duphaston 5 mg Tablet causes secretive changes in the uterus's endometrium lining, promotes the breast's development, relaxes the uterus, blocks the maturation and release of the follicle, and retains pregnancy.

Storage

Store in a cool and dry place away from sunlight
Side effects of Duphaston 5 mg Tablet
  • Lie down or take a nap in dark and quiet room.
  • To avoid dehydration, drink plenty of fluids.
  • In case of mild to moderate migraine, you can take over-the-counter pain relievers like paracetamol or ibuprofen.
  • Apply an ice pack or cool cloth on your forehead.
  • Try relaxation techniques such as yoga, meditation, or deep breathing to reduce stress and relax.
  • Avoid foods and drinks that trigger migraine such as chocolate, alcohol, cheese, caffeine, processed meats, artificial sweeteners and dried fruits.
  • Manage your stress by eating healthy, exercising and a regular sleep schedule.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink fluids: Water, clear broth, or electrolyte-rich beverages.
  • Follow a balanced diet, which would be rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.
  • Mindfulness: Manage stress with meditation, deep breathing or yoga.
  • Stay away from smoke, dust and other irritants.
  • Get adequate rest to facilitate recovery.
  • Wash hands and avoid close contact, do not share personal items.

What if I have taken an overdose of Duphaston 5 mg Tablet

Do not take more than the prescribed dose of Duphaston 5 mg Tablet as it may cause an overdose. The symptoms of overdose include vomiting, nausea, dizziness and lack of energy. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Inform your physician if you are allergic to Duphaston 5 mg Tablet , peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterine cancer), or are undergoing estrogen plus progestin treatment. 
  • Duphaston 5 mg Tablet with estrogens should not be used as it may increase the chance of getting heart attacks, strokes, breast cancer, and blood clots. 
  • Therefore, tell your doctor before using the Duphaston 5 mg Tablet if you have had a heart attack, stroke, blood clot, liver problems, or kidney problems. 
  • Patients with conditions like galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not take Duphaston 5 mg Tablet .
  • Let your doctor know if you are pregnant, breastfeeding or planning to get pregnant.
  • If you have asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, thyroid disorder, or have high calcium levels in your blood, inform your doctor before taking Duphaston 5 mg Tablet . 
  • Maintain caution while driving a motor vehicle, as Duphaston 5 mg Tablet may cause dizziness or drowsiness in some patients. 
  • If you are using Duphaston 5 mg Tablet before any lab tests or biopsies, tell your doctor about this, as it can affect the report values. 
  • This medicine is not recommended for use in children below 12 years of age.
  • It is always important to check for the expiry of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Regular exercise and physical activity can minimize hot flushes and improve sleep. Weight-bearing exercises can also help strengthen bones. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take a minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Duphaston 5 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Duphaston 5 mg Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Duphaston 5 mg Tablet can be safely used in pregnant women. Your doctor will weigh the benefits and potential risks before prescribing them. If you have any concerns regarding this, discuss them with the doctor.

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Breast Feeding

Caution

Duphaston 5 mg Tablet should be used in breastfeeding mothers only if the benefits outweigh the risks. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Driving

Caution

It is advised to drive with caution after taking Duphaston 5 mg Tablet as it may interfere with driving capabilities. It can make you feel drowsy.

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Liver

Consult your doctor

Limited information was available for the use of Duphaston 5 mg Tablet in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using Duphaston 5 mg Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Limited information was available for the use of Duphaston 5 mg Tablet in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using Duphaston 5 mg Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Duphaston 5 mg Tablet is not recommended for children below 12 years of age.

Have a query?

FAQs

Duphaston 5 mg Tablet is used in the treatment of infertility, prevention of miscarriages, dysfunctional uterine bleeding, irregular menses cycle, dysmenorrhoea (painful periods), endometriosis (a disorder in which tissue that normally lines the uterus grows outside the uterus), threatened and habitual abortion associated with proven progesterone deficiency.

Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high levels of estrogen, and women can have decreased sex drive (libido), weight gain, or gallbladder problems.

Yes, Duphaston 5 mg Tablet might cause ovarian cysts. These are small fluid-filled sacs that can occur on ovaries. These are harmless. They disappear without treatment.

Duphaston 5 mg Tablet helps in preparing the endometrium potential for pregnancy after ovulation. It thickens the lining of the endometrium to accept a fertilized egg. It also prevents muscle contractions of the uterus that would reject an egg in the uterus. So, if the body has a high progesterone level, ovulation will not occur then.

Yes, Duphaston 5 mg Tablet may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking Duphaston 5 mg Tablet , please consult your doctor.

Yes, Duphaston 5 mg Tablet can be taken every day. This medicine is prescribed once daily, preferably in the evening or at bedtime. Please take it in the dose and duration as advised by the doctor.

Yes, Duphaston 5 mg Tablet is used to prevent habitual miscarriage and regular abortion. Your doctor will decide whether you should continue or stop taking Duphaston 5 mg Tablet . Do not take medication of your own or self-medicate.

Yes, Duphaston 5 mg Tablet is synthetic or man-made progesterone, which is very similar to progesterone made by your body. It is taken in various gynaecological problems when your body is unable to make a sufficient amount of natural progesterone.

The most common side effects of Duphaston 5 mg Tablet are migraines/headaches, nausea, menstrual disorders and breast pain/tenderness.

There is no clinical evidence that Duphaston 5 mg Tablet decreases fertility at therapeutic doses. However, taking it only after consulting any obstetrician/gynaecologist is better.

Duphaston 5 mg Tablet should be taken for the duration prescribed by the doctor. The dose and duration will depend upon your condition and response to treatment. Talk to your doctor if you have any concerns.

In some cases, Duphaston 5 mg Tablet may increase the risk of birth defects such as hypospadias (the opening of the urethra is not located at the tip of the penis) and congenital heart defects.

Dydrogesterone is a synthetic form of progesterone. Dydrogesterone is used in conditions when the body does not make enough progesterone.

Do not take Duphaston 5 mg Tablet if you are allergic to any of its components, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or are undergoing oestrogen plus progestin treatment.

If you forget a dose, take the missed dose as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose.

Duphaston 5 mg Tablet may cause breast pain and tenderness as a side effect. Consult the doctor if the condition persists or worsens or if you notice any other changes in your breast such as a lump.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot ? C, ?G? Block, Bandra-Kurla Complex, Bandra (East), Mumbai ? 400 051, India.
Other Info - DUP0011

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 15, 2025 | 11:02 AM IST

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Reference

  1. https://http://www.hpra.ie/img/uploaded/swedocuments/Licence_PA2010-010-001_21092021144738.pdf
  2. https://www1.ndmctsgh.edu.tw/pharm/pic/medinsert/005DUP05E.pdf
  3. https://data.health.gov.il/drugs/alonim/Duphaston_dr_1410193172635.pdf
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