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  3. Elava 2000 Injection 0.5 ml

Elava 2000 Injection 0.5 ml, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Elava 2000 Injection is used to treat anaemia due to chronic kidney disease and chemotherapy. It contains Erythropoietin alfa, human recombinant which works by stimulating the bone marrow to make more red blood cells. This medicine may sometimes cause side effects such as high blood pressure, nausea, vomiting and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ERYTHROPOIETIN ALFA, HUMAN RECOMBINANT-20000IU

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Elava 2000 Injection

Elava 2000 Injection belongs to a class of drugs known as erythropoiesis-stimulating agent (ESA) primarily used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and anaemia due to chemotherapy (cancer treatment). Anaemia is reduced levels of haemoglobin and red blood cells (RBCs) in the blood. Chronic kidney disease (CKD) patients slowly develop anaemia, which gets worse as the disease progresses. Also, the treatment of cancer, including chemotherapy and radiotherapy, causes anaemia in cancer patients.

Elava 2000 Injection contains ‘Erythropoietin alfa, human recombinant’. Elava 2000 Injection works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Elava 2000 Injection is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC), preventing anaemia (lack of haemoglobin and RBC in the blood).

Elava 2000 Injection will be administered by a healthcare professional; do not self-administer. You may experience high blood pressure, nausea, vomiting and fever. Most of these side effects of Elava 2000 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Elava 2000 Injection or any other medicines, please tell your doctor. Elava 2000 Injection should not be taken in conditions like heart disease, high blood pressure, or liver disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Elava 2000 Injection . Elava 2000 Injection may affect your ability to drive and use machines as Elava 2000 Injection may cause fits disorder during the first 90 days of treatment. 

Uses of Elava 2000 Injection

Treatment of Anemia due to chronic kidney disease, Anemia due to chemotherapy.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Elava 2000 Injection may be administered by your doctor, or you may be told to inject the medication yourself at home. Your doctor will train you on how to use Elava 2000 Injection at home. Check the label for directions and use it as advised by the doctor. Elava 2000 Injection should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm.• Rotate the injection site each time. Do not inject into the areas where the skin is tender, red, bruised, hard, scarred or has stretch marks.

Medicinal Benefits

Elava 2000 Injection helps in the treatment of anemia which may happen due to chronic kidney disease and cancer chemotherapy. Elava 2000 Injection works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Elava 2000 Injection is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood). Besides this Elava 2000 Injection is also used for the treatment of anemia caused by a medicine known as zidovudine for the treatment of HIV (human immunodeficiency viruses). Elava 2000 Injection  also decreases the requirement for blood cell transfusions.

How Elava 2000 Injection Works

Elava 2000 Injection contains ‘Erythropoietin alfa, human recombinant’. Elava 2000 Injection works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Elava 2000 Injection is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC), preventing anaemia (lack of haemoglobin and RBC in the blood).

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Elava 2000 Injection 0.5 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.

What if I have taken an overdose of Elava 2000 Injection

Since Elava 2000 Injection is administered by a healthcare professional, an overdose is unlikely to occur. Signs and symptoms of overdose may include excessive and/or rapid increase in haemoglobin concentration and cardiovascular events. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are known to be allergic to Elava 2000 Injection or any other medicines, please tell your doctor. Elava 2000 Injection should not be taken in conditions like high blood pressure, heart disease, heart attack, blood clot in the brain (stroke), fits disorder, liver disease, or kidney disease. Before taking Elava 2000 Injection inform your doctor if you have any type of cancer or skin reactions. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Elava 2000 Injection . Elava 2000 Injection may affect your ability to drive and using machines as Elava 2000 Injection may cause fits to disorder during the first 90 days of treatment. Elava 2000 Injection should not be used for children below 1 month of age during treatment of anemia due to chronic kidney disease. Elava 2000 Injection should not be used for children below 5 years of age during treatment of anemia due to chemotherapy.

Drug-Drug Interactions

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ErythropoietinPomalidomide
Severe
ErythropoietinThalidomide
Severe

Drug-Drug Interactions

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ErythropoietinPomalidomide
Severe
How does the drug interact with Elava 2000 Injection 0.5 ml:
Pomalidomide can cause serious blood clots and taking it alongside Elava 2000 Injection 0.5 ml may enhance the risk.

How to manage the interaction:
Co-administration of Elava 2000 Injection 0.5 ml with Pomalidomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ErythropoietinThalidomide
Severe
How does the drug interact with Elava 2000 Injection 0.5 ml:
Taking thalidomide with Elava 2000 Injection 0.5 ml may increase the risk or severity of thromboembolism(a circulating blood clot that gets stuck and causes an obstruction).

How to manage the interaction:
Although taking Elava 2000 Injection 0.5 ml and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ErythropoietinCarfilzomib
Severe
How does the drug interact with Elava 2000 Injection 0.5 ml:
Carfilzomib can cause serious blood clots and taking it alongside Elava 2000 Injection 0.5 ml may enhance the risk.

How to manage the interaction:
Co-administration of Elava 2000 Injection 0.5 ml with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ErythropoietinLenalidomide
Severe
How does the drug interact with Elava 2000 Injection 0.5 ml:
Combining Elava 2000 Injection 0.5 ml with Lenalidomide can increase the risk of Thrombosis(formation of a blood clot ).

How to manage the interaction:
Although there is an interaction between Elava 2000 Injection 0.5 ml and Lenalidomide, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  • Your doctor may get your blood tests done frequently to examine the levels of blood cells, hemoglobin, and electrolytes such as potassium in your blood.
  • Eat food that is rich in iron, vitamin B12, and folic acid.
  • Eat food like leafy, green vegetables, fish, eggs, and liver.
  • Do mild to moderate exercise.

Habit Forming

No

Therapeutic Class

ERYTHROPOIESIS STIMULATING AGENTS (ESAs)

Elava 2000 Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known that Elava 2000 Injection may interact with alcohol. Therefore, avoid drinking alcohol while using Elava 2000 Injection .

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Pregnancy

Caution

Elava 2000 Injection should not be taken until prescribed. Your doctor will decide what is the best treatment for you. Please consult your doctor.

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Breast Feeding

Caution

Inform your doctor before taking Elava 2000 Injection . Your doctor will advise you to either stop or continue treatment.

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Driving

Caution

Elava 2000 Injection may affect your ability to drive and using machines as Elava 2000 Injection may cause fits to disorder during the first 90 days of treatment.

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Liver

Caution

Take Elava 2000 Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Elava 2000 Injection is safely given to the kidney patients only if prescribed by your doctor.

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Children

Caution

Elava 2000 Injection should be used in children only when prescribed by a doctor.

Have a query?

FAQs

Elava 2000 Injection is used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and chemotherapy (cancer treatment).

Yes, Elava 2000 Injection can be used for children above 1 month of age during treatment of anemia due to chronic kidney disease. Elava 2000 Injection can be used for children above 5 years of age during treatment of anemia due to chemotherapy. The effectiveness of Elava 2000 Injection and side effects observed in children is the same as adults, and used only when prescribed by a doctor.

Yes, Elava 2000 Injection may increase the blood pressure. During initial treatment with Elava 2000 Injection , blood pressure should be examined and those who have high blood pressure should take proper methods to regulate blood pressure. Your doctor may stop Elava 2000 Injection if the blood pressure continues uncontrolled.

Elava 2000 Injection works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Elava 2000 Injection is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood).

The most common side effects of Elava 2000 Injection are high blood pressure, nausea, vomiting, and fever, diarrhea, feeling upset in the stomach, skin rashes, stuffy nose, sore throat, bone, or muscle pain. Most of these side effects of Elava 2000 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ELA0107

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:48 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.1193.pdf
  2. https://www.drugs.com/mtm/epoetin-alfa.html

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