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compositionComposition:ELTROMBOPAG-50MG
prescription
Prescription Medicine
info
Eltropag Tablet 7's

Eltropag Tablet is used to treat low platelet count. It contains Eltrombopag which works by causing the cells in the bone marrow to produce more platelets. In some cases, this medicine may cause side effects such as nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, and cough. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ELTROMBOPAG-50MG

Manufacturer/Marketer :

MEDICAMEN BIOTECH LTD

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Eltropag Tablet

Eltropag Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Eltropag Tablet is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused by the hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Eltropag Tablet contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone, stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Eltropag Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Eltropag Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

In some cases, Eltropag Tablet can cause common side effects like nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Eltropag Tablet or any other medicines before starting Eltropag Tablet. Consult the doctor if you are pregnant or planning to conceive. Eltropag Tablet is not indicated for use in breastfeeding since it passes into the breast milk.

Uses of Eltropag Tablet

Eltropag Tablet is used in the treatment of low platelet count (thrombocytopenia) in various blood-related disorders. The detailed uses of Eltropag Tablet are as follows:

  • Treats Chronic Immune Thrombocytopenia (ITP): Eltropag Tablet is used to treat chronic ITP in patients who have not responded adequately to treatments such as immunoglobulins, corticosteroids, and splenectomy (surgical removal of spleen).
  • Manages Thrombocytopenia in Hepatitis C Virus (HCV) infection: Eltropag Tablet helps increase platelet counts in chronic HCV patients, making it safer for them to start and continue treatment with interferon.
  • Treats Severe Aplastic Anaemia (SAA): Eltropag Tablet is used for patients with SAA who have not responded to immunosuppressive treatment, helping to stimulate bone marrow to produce more blood cells.
  • Prevents Bleeding Episodes: By increasing platelet count, Eltropag Tablet reduces the risk of bleeding associated with low platelet levels in various blood disorders.

Key Benefits

  • Eltropag Tablet contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults.
  • Eltropag Tablet works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets.
  • The increase in these bone marrow cells stimulates the production of platelets. Thus Eltropag Tablet prevents bleeding episodes by increasing the number of platelets in the blood.
Side effects of Eltropag Tablet
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Directions for Use

  • Eltropag Tablet can be taken on an empty stomach, at least 1 hour before or 2 hours after eating.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Eltropag Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Eltropag Tablet Works

Eltropag Tablet contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Eltropag Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Eltropag Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.
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Alcohol

Caution

Limit alcohol intake, along with Eltropag Tablet, to attain the maximum efficacy of Eltropag Tablet and rule out any possibility of worsening of side effects.

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Pregnancy

Unsafe

Eltropag Tablet is not recommended in pregnancy. It may affect and harm the developing baby. Please consult your doctor if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Eltropag Tablet is excreted into the breast milk. Please consult your doctor for more information before taking Eltropag Tablet if you are a nursing mother.

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Driving

Caution

Eltropag Tablet may cause dizziness and tiredness affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Eltropag Tablet. Eltropag Tablet may cause an increase in liver enzymes. Your doctor may start the treatment with a lower dose of Eltropag Tablet.

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Kidney

Consult your doctor

Eltropag Tablet should be used with caution in cases of renal impairment. It is advised to seek doctor advice before starting Eltropag Tablet if you have any kidney problems.

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Children

Caution

Eltropag Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Eltropag Tablet. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Safe if prescribed

Eltropag Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Eltropag Tablet

Take Eltropag Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include rash, slowed heartbeat, and excessive tiredness. It may also cause life-threatening blood clots. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat natural and healthy foods by cutting down on fatty and sodium-processed foods.
  • Exercise regularly to maintain good health.
  • Avoid smoking and alcohol intake.
  • Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
  • A high-protein diet, such as lean meat, chicken, crab, turkey, beef and fish, can help increase platelet count.
  • Eating Papayaa is the best natural remedy to increase your platelet count, and you can also use Papayaa leaves mixture.
  • Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
  • Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

Have a query?

How Soon It Starts Working

The time required for Eltropag Tablet to start to work: Eltropag Tablet ideally shows its action within 2 to 6 hours after administration. The time for which the effects of Eltropag Tablet last: The duration of action for Eltropag Tablet is clinically unknown.

What if you forget to take Eltropag Tablet

If you miss a dose, use it as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the next dose at the regular time.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • If you are known to be allergic to Eltropag Tablet or other medicines, please inform your doctor in advance.
  • Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Eltropag Tablet.
  • Take Eltropag Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Eltropag Tablet.
  • Eltropag Tablet is not recommended during pregnancy since it may have harmful effects on the foetus.
  • Consult your doctor before using Eltropag Tablet if you are a breastfeeding mother.
  • Do not drive or operate machinery since Eltropag Tablet may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive.
  • Avoid or limit alcohol consumption with Eltropag Tablet as it may affect the efficacy of Eltropag Tablet.
  • Eltropag Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

Drug-Drug Interactions

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Drug-Drug Interactions: Eltropag Tablet may interact with antacids, cholesterol-lowering drugs (statins), vitamin and mineral supplements (iron, calcium, magnesium, aluminium, selenium and zinc), anti-cancer drugs (methotrexate, topotecan), drugs for rheumatoid arthritis (ciclosporin, azathioprine), HIV/AIDS drugs (lopinavir, ritonavir), corticosteroids, and steroid hormones (danazol).

Drug-Food Interactions: Take Eltropag Tablet at least two hours before or four hours after consuming dairy products, calcium-enriched foods, and fortified juices, as these interfere with the absorption of Eltropag Tablet.

Drug-Disease Interactions: People with blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, and liver or kidney diseases should consult the doctor before taking Eltropag Tablet.

EltrombopagAluminium hydroxide
Critical
EltrombopagFerrous gluconate
Critical

Drug-Drug Interactions

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EltrombopagAluminium hydroxide
Critical
How does the drug interact with Eltropag Tablet:
Coadministration of Eltropag Tablet and aluminum hydroxide may interfere with the absorption of Eltropag Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Eltropag Tablet with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EltrombopagFerrous gluconate
Critical
How does the drug interact with Eltropag Tablet:
Ferrous gluconate can make Eltropag Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Eltropag Tablet with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Eltropag Tablet on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.
EltrombopagCalcium chloride
Critical
How does the drug interact with Eltropag Tablet:
When Eltropag Tablet is mixed with Calcium chloride, the amount of Eltropag Tablet in the blood can decrease. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Eltropag Tablet with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EltrombopagMagnesium citrate
Critical
How does the drug interact with Eltropag Tablet:
Taking magnesium citrate with Eltropag Tablet can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking Magnesium citrate with Eltropag Tablet is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Eltropag Tablet on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.
EltrombopagFerric maltol
Critical
How does the drug interact with Eltropag Tablet:
Ferric maltol can make Eltropag Tablet less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.

How to manage the interaction:
Taking Ferric maltol with Eltropag Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Eltropag Tablet on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.
EltrombopagMagnesium oxide
Critical
How does the drug interact with Eltropag Tablet:
Coadministration of Magnesium oxide with Eltropag Tablet can impair the absorption of Eltropag Tablet which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Eltropag Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EltrombopagInterferon alfacon-1
Severe
How does the drug interact with Eltropag Tablet:
Coadministration of Eltropag Tablet and Interferon alfacon-1 can increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Eltropag Tablet and Interferon alfacon-1 together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
EltrombopagInterferon alfa-2b
Severe
How does the drug interact with Eltropag Tablet:
When Interferon alfa-2b is taken with Eltropag Tablet, it can lower the metabolism of Eltropag Tablet.

How to manage the interaction:
There may be a possibility of interaction between Eltropag Tablet and Interferon alfa-2b, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to call a doctor right away. These symptoms include chronic hepatitis C, advanced liver disease, cirrhosis, liver failure, and other liver-related problems. You should also seek medical attention if you experience confusion, fever, joint pain, swelling, or any other unusual symptoms. Do not discontinue any medications without consulting a doctor.
EltrombopagPeginterferon alfa-2a
Severe
How does the drug interact with Eltropag Tablet:
Combining Eltropag Tablet with Peginterferon alfa-2a can lower the metabolism of Eltropag Tablet. This can increase the risk or severity of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Eltropag Tablet and Peginterferon alfa-2a, but it can be taken if prescribed by a doctor. If you have any of these symptoms like confusion, changes in consciousness, harmful substances in the blood, bleeding from enlarged veins, bleeding, infection of the abdominal wall, complications, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, feeling tired, feeling sick, throwing up, bleeding, pain, dark urine, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
EltrombopagTeriflunomide
Severe
How does the drug interact with Eltropag Tablet:
Coadministration of Eltropag Tablet with Teriflunomide can increase the risk or severity of liver damage.

How to manage the interaction:
Co-administration of Eltropag Tablet with Teriflunomide can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, bleeding, dark colored urine, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Eltropag Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. It is also used to treat severe aplastic anemia (SAA) in adults.
Eltropag Tablet contains Eltrombopag that stimulates platelet's production (helps in clotting) from megakaryocytes (bone marrow cells). Thus Eltropag Tablet lowers the risk of bleeding episodes in diseases like immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA).
Do not stop using Eltropag Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
Eltropag Tablet should be used with caution and only under doctor's supervision in cases of any allergic reactions, blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases.
Eltropag Tablet decreases the risk of bleeding by increasing the platelet count in your body. However, you are advised to stay away from activities that may increase your risk of bleeding like contact sports and using sharp objects like razors and nail cutters.
It is advised to take Eltropag Tablet on an empty stomach. Please take Eltropag Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Eltropag Tablet.
Eltropag Tablet should be swallowed whole. Do not chew or crush the tablets.
It is usually taken once a day on an empty stomach, at least 1 hour before or 2 hours after eating. Take Eltropag Tablet at around the same time every day.
It may take up to 2 weeks for patients to respond to Eltropag Tablet.
Eltropag Tablet should not be taken with foods, beverages, or other medicines that contain high concentrations of aluminium, calcium, iron, magnesium, selenium and zinc.
Eltropag Tablet should be stored in a cool and dry place away from sunlight. Keep out of sight and reach of children.
Eltropag Tablet can cause or increase the risk of severe liver issues. Check with your doctor straight away if you or your child experience nausea or vomiting, dark urine, light-coloured stools, right upper stomach pain, unusual exhaustion, or yellow eyes or skin while taking this medication.
Please take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

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Country of origin

India
Other Info - ELT0097

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