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  3. Endset-MD Tablet

Endset-MD Tablet, Pack of 1 Tablet
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Endset-MD Tablet is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery. It contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause common side effects such as constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. Before taking this medication, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medicines you are taking and any pre-existing medical conditions.

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Composition :

ONDANSETRON-4MG

Manufacturer/Marketer :

Mathis Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

About Endset-MD Tablet

Endset-MD Tablet is primarily used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response of the body to expel the stomach contents from the mouth forcefully.

Endset-MD Tablet contains ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

You may experience common side effects such as constipation, headache, diarrhoea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. If the side effects persist or worsen, please consult your doctor.

Before using Endset-MD Tablet, inform your doctor if you are allergic to any of its ingredients. Endset-MD Tablet should be used during pregnancy and breastfeeding only if prescribed by a doctor.

Uses of Endset-MD Tablet

Endset-MD Tablet is used in the prevention of Nausea and Vomiting. The detailed uses of Endset-MD Tablet are as follows:

  • Chemotherapy-Induced Nausea: Endset-MD Tablet is frequently prescribed to alleviate nausea and vomiting caused by chemotherapy treatments.
  • Radiation Therapy Support: Endset-MD Tablet can help manage nausea and vomiting experienced by patients undergoing radiation therapy, improving treatment tolerance.
  • Postoperative Nausea Relief: Many patients experience nausea after surgical procedures, and Endset-MD Tablet is effective in controlling and reducing these symptoms.

Have a query?

Directions for Use

  • Endset-MD Tablet can be taken with or without food, as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Place Endset-MD Tablet on your tongue and allow it to dissolve before swallowing.
  • Do not swallow Endset-MD Tablet as a whole.
  • Make sure your hands are dry before handling Endset-MD Tablet.

Medicinal Benefits

  • Endset-MD Tablet is an antiemetic medication primarily used to prevent and treat nausea and vomiting associated with conditions such as cancer chemotherapy, radiation treatment, pregnancy, or motion sickness and surgery.
  • Endset-MD Tablet contains Ondansetron, which works by inhibiting the release of serotonin, thereby preventing nausea and vomiting.

How Endset-MD Tablet Works

Endset-MD Tablet contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Endset-MD Tablet prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Storage

• Store in a cool and dry place away from sunlight.• Keep Endset-MD Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Endset-MD Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Avoid rubbing or scratching the affected area, as this can cause further irritation and discomfort.
  • Consider using a humidifier to add moisture to the air and help reduce the sensation.
  • Seek medical attention if the sensation is severe, persistent, or worsens over time.
  • Avoid extreme temperatures, such as hot or cold showers, that can exacerbate the sensation.
  • Wear light, breathable clothing to help keep the body cool and reduce the sensation.
  • Avoid triggers that can cause the sensation, such as spicy foods or hot drinks.
  • Use cool compresses or fans to help lower body temperature and reduce the sensation.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Endset-MD Tablet

Do not take more than the prescribed dose of Endset-MD Tablet, as it may lead to an overdose. Symptoms of an overdose may include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness, or light-headedness. If you suspect that you have taken an overdose of this medication or notice any unusual symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not use Endset-MD Tablet if you are allergic to any of its ingredients.
  • Avoid using Endset-MD Tablet if you are taking apomorphine (a medicine used to treat Parkinson's disease), as it may cause a sharp drop in blood pressure and even fainting.
  • Inform your doctor before using Endset-MD Tablet if you have any medical conditions, such as severe constipation, bowel obstruction, depression, electrolyte imbalance, heart or blood vessel problems (such as irregular heartbeats and high blood pressure), diabetes, liver problems, or a history of tonsils or adenoid removal surgery.
  • Tell your doctor if you are taking any medications for depression, as using them alongside Endset-MD Tablet may increase the risk of serotonin syndrome, a potentially life-threatening condition.
  • Endset-MD Tablet is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.
  • Avoid breastfeeding while taking Endset-MD Tablet, as small amounts of the medicine may pass into breast milk.
  • Avoid consuming alcohol while taking Endset-MD Tablet, as it may worsen the side effects like drowsiness.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronBupropion
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Endset-MD Tablet:
Taking Endset-MD Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Endset-MD Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronBupropion
Severe
How does the drug interact with Endset-MD Tablet:
When bupropion, is combined with Endset-MD Tablet it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Endset-MD Tablet along with bupropion can lead to interaction, it can be taken if recommended by a doctor. If you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.
OndansetronCitalopram
Severe
How does the drug interact with Endset-MD Tablet:
When Endset-MD Tablet, is taken with citalopram, the risk of serotonin syndrome increases. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Endset-MD Tablet along with citalopram can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach pain, nausea, vomiting, and diarrhea while taking these medications, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronVenlafaxine
Severe
How does the drug interact with Endset-MD Tablet:
When Endset-MD Tablet is taken with venlafaxine, it can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Endset-MD Tablet along with venlafaxine can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking these medications. Do not discontinue any medications without a doctor's advice.
OndansetronBuspirone
Severe
How does the drug interact with Endset-MD Tablet:
Using Buspirone together with Endset-MD Tablet can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Co-administration of Endset-MD Tablet with buspirone can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
OndansetronIloperidone
Severe
How does the drug interact with Endset-MD Tablet:
Taking Endset-MD Tablet with Iloperidone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Endset-MD Tablet along with Iloperidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronMaprotiline
Severe
How does the drug interact with Endset-MD Tablet:
When Endset-MD Tablet is taken with maprotiline, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Endset-MD Tablet along with maprotiline can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
OndansetronAmiodarone
Severe
How does the drug interact with Endset-MD Tablet:
Coadministration of Endset-MD Tablet with amiodarone can lead to or increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Endset-MD Tablet with amiodarone together can result in interaction, it should be taken only if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
OndansetronEfavirenz
Severe
How does the drug interact with Endset-MD Tablet:
Taking Endset-MD Tablet with efavirenz increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Endset-MD Tablet along with efavirenz can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronChloroquine
Severe
How does the drug interact with Endset-MD Tablet:
Using chloroquine together with Endset-MD Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Endset-MD Tablet and chloroquine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals throughout the day and eat slowly to help digestion.
  • If you are sensitive to food smells, try eating cold or room-temperature foods instead of hot ones.
  • Avoid acidic foods or drinks like orange or grapefruit juice.
  • After your meals, rest with your head elevated about 12 inches above your head.
  • Drink liquids or water between meals rather than during meals.
  • Eat when you are least nauseated to help prevent discomfort.
  • Avoid consuming greasy or oily foods, as these foods can trigger nausea and vomiting.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid makeup that has been lost due to vomiting.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Endset-MD Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Alcohol has no known direct interaction with Endset-MD Tablet. However, it is advisable to avoid consuming alcohol while taking Endset-MD Tablet, as it may worsen the side effects like drowsiness.

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Pregnancy

Caution

Endset-MD Tablet should be used during pregnancy only if prescribed by a doctor. It is generally not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

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Breast Feeding

Caution

Avoid breastfeeding while taking Endset-MD Tablet, as small amounts of the medicine may pass into breast milk.

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Driving

Caution

Endset-MD Tablet does not affect your ability to drive. However, if you experience drowsiness or blurred vision after taking Endset-MD Tablet, avoid driving or operating any heavy machinery.

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Liver

Caution

In individuals with liver problems, the use of Endset-MD Tablet is allowed if prescribed by a doctor. However, patients with severe liver impairment should take a low dose of Endset-MD Tablet as much as possible. Do not take more than 8 mg of Endset-MD Tablet per day in case of liver disease.

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Kidney

Safe if prescribed

The use of Endset-MD Tablet is considered safe in patients with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

Endset-MD Tablet should not be given to children below 4 years of age, as its safety and effectiveness have not been established in this age group. The use of Endset-MD Tablet is safe in children above 4 years of age if prescribed by a doctor.

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Heart

Inform your doctor if you have any heart problems before using Endset-MD Tablet.

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Geriatrics

Consult your doctor

Limited information available about the use of Endset-MD Tablet in geriatric patients. Please consult your physician.

FAQs

Endset-MD Tablet is an antiemetic medication primarily used to prevent and treat nausea and vomiting associated with conditions such as cancer chemotherapy, radiation treatment, and surgery.

Endset-MD Tablet contains Ondansetron (an antiemetic) that works by blocking the action of a chemical (serotonin) in the body that triggers nausea and vomiting. As a result, Endset-MD Tablet helps prevent the sensation of nausea and vomiting.

The common side effects of Endset-MD Tablet may include constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. However, not every person experiences these side effects, and some of the unpleasant effects of Endset-MD Tablet do not require medical attention. If the side effects persist or worsen, please consult your doctor.

You should not use Endset-MD Tablet if you are allergic to any of its ingredients. Also, avoid using Endset-MD Tablet if you are taking apomorphine (a medicine used to treat Parkinson's disease), as it may cause a sharp drop in blood pressure and even fainting.

Endset-MD Tablet is an anti-emetic oral medication that rapidly dissolves in your mouth and works within a few seconds.

Always use Endset-MD Tablet exactly as instructed by your doctor. Check Endset-MD Tablet for any damage and use only undamaged strips/films. Make sure your fingers are dry and your mouth is empty before putting the strip/film on your tongue. The strip/film should melt on your tongue in a few seconds without using saliva or needing water, and it can then be swallowed.

Endset-MD Tablet should be used during pregnancy only if prescribed by a doctor. It is generally not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

Country of origin

India
Other Info - EN58505

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Reference

  1. https://pdf.hres.ca/dpd_pm/00064766.PDF
  2. https://pdf.hres.ca/dpd_pm/00072452.PDF
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020103s035_020605s019_020781s019lbl.pdf
  4. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=52dc6871-47d3-11dc-99cc-f742b487c00e
  5. https://www.nps.org.au/assets/medicines/3f23408b-a751-4a81-82af-a7d7009755a5-reduced.pdf
  6. https://medlineplus.gov/druginfo/meds/a601209.html
  7. https://www.drugs.com/ondansetron.html
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