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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Enzamide 40mg Capsule is used to treat prostate cancer. It contains Enzalutamide, an androgen receptor blocker (inhibitor) that blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow; this can slow the growth of the cancer and may shrink it. Enzalutamide is only for use in men. Men using this medication must use effective birth control whenever they have sex during their treatment and for three months after their final dose.

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Whats That

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Composition :

ENZALUTAMIDE-40MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Enzamide 40mg Capsule

Enzamide 40mg Capsule belongs to a group of medicines known as androgen receptor inhibitors. It is used to treat prostate cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.

Enzamide 40mg Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Use this medicine as directed by your doctor. You may sometimes experience trouble breathing (pneumonia), weakness or feeling more tired than usual, back pain, diarrhoea, pain in your joints, swelling (in your hands, arms, legs or feet), muscle or bone pain, muscle weakness, headache, cold-like symptoms, dizziness, high blood pressure and trouble falling or staying asleep (insomnia). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Enzalutamide is only for use in men. Men using this Enzamide 40mg Capsule must use effective birth control whenever they have sex during your treatment and for three months after their final dose. In rare cases, Enzamide 40mg Capsule may cause seizures, so tell your doctor if you have or have ever had seizures. Because of the risk of seizure associated with Enzamide 40mg Capsule use, patients should be advised of the risk of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Consumption of alcohol is strictly avoided.

Uses of Enzamide 40mg Capsule

Treatment of Prostate Cancer

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush or chew it.

Solution: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Medicinal Benefits

Enzamide 40mg Capsule contains Enzalutamide, which belongs to a group of medicines known as androgen receptor inhibitors. Most prostate cancers require testosterone to grow. In men, the testicles produce the majority of testosterone. Adrenal glands (Just above each kidney) produce a small quantity of testosterone. Enzalutamide is preventing testosterone from reaching cancer cells in the prostate. This can inhibit the growth of the cancer and even cause it to shrink.

How Enzamide 40mg Capsule Works

Enzamide 40mg Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Storage

Store in a cool and dry place away from sunlight
Side effects of Enzamide 40mg Capsule
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
  • Consume calcium-rich dairy products for bone health.
  • Eat green and leafy vegetables for essential nutrients.
  • Include lean protein sources like eggs and whole grains.
  • Use herbs and spices for added flavor and nutrition.
  • Choose fortified foods for extra nutritional benefits.
  • Get plenty of sleep for overall health and well-being.

What if I have taken an overdose of Enzamide 40mg Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Enzamide 40mg Capsule may include seizures. Seek immediate medical attention if you observe any symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Enzamide 40mg Capsule if you are allergic or hypersensitive to any component present in it. You must take Enzalutamide according to the instructions your doctor or pharmacist gives you. You must take Enzalutamide exactly as prescribed by your doctor or pharmacist. You must take the correct dose, not more or less. Consult your healthcare team before discontinuing Enzamide 40mg Capsule or missing a dose. Talk to your doctor before taking Enzamide 40mg Capsule if you have severe allergic reactions to medicines or foods or suffer from any medical illness. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Drug-Drug Interactions

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EnzalutamideDronedarone
Critical
EnzalutamideZiprasidone
Critical

Drug-Drug Interactions

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EnzalutamideDronedarone
Critical
How does the drug interact with Enzamide 40mg Capsule:
Co-administration of Enzamide 40mg Capsule and Dronedarone together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Enzamide 40mg Capsule and Dronedarone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideZiprasidone
Critical
How does the drug interact with Enzamide 40mg Capsule:
Taking Enzamide 40mg Capsule with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Enzamide 40mg Capsule with Ziprasidone is not recommended, as it may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
EnzalutamideRanolazine
Critical
How does the drug interact with Enzamide 40mg Capsule:
Taking Enzamide 40mg Capsule may decrease the blood levels of Ranolazine, which may make Ranolazine less effective.

How to manage the interaction:
Taking Enzamide 40mg Capsule with Ranolazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideRegorafenib
Critical
How does the drug interact with Enzamide 40mg Capsule:
Taking Enzamide 40mg Capsule with Regorafenib may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Enzamide 40mg Capsule with Regorafenib is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideLurasidone
Critical
How does the drug interact with Enzamide 40mg Capsule:
Co-administration of Lurasidone with Enzamide 40mg Capsule may result in significantly lower blood levels of Lurasidone, making the medication less effective.

How to manage the interaction:
Taking Lurasidone with Enzamide 40mg Capsule is not recommended as it may lead to interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EnzalutamideSirolimus
Severe
How does the drug interact with Enzamide 40mg Capsule:
Coadministration of Enzamide 40mg Capsule with Sirolimus may decrease the blood levels of Sirolimus, which may lead to reduced treatment outcomes.

How to manage the interaction:
Although taking Enzamide 40mg Capsule and Sirolimus together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medication without consulting a doctor.
EnzalutamideNimodipine
Severe
How does the drug interact with Enzamide 40mg Capsule:
Co-administration of Nimodipine with Enzamide 40mg Capsule may make the medication less effective.

How to manage the interaction:
Although taking Nimodipine and Enzamide 40mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EnzalutamideIbrutinib
Severe
How does the drug interact with Enzamide 40mg Capsule:
Co-administration of Enzamide 40mg Capsule may decrease the blood levels of Ibrutinib, which may make Ibrutinib less effective in treating your condition.

How to manage the interaction:
Although taking Enzamide 40mg Capsule and Ibrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EnzalutamideTacrolimus
Severe
How does the drug interact with Enzamide 40mg Capsule:
Taking Tacrolimus with Enzamide 40mg Capsule may reduce the levels of Tacrolimus, which may make Tacrolimus less effective in treating your condition.

How to manage the interaction:
Although taking Tacrolimus and Enzamide 40mg Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnzalutamideFelodipine
Severe
How does the drug interact with Enzamide 40mg Capsule:
Taking Enzamide 40mg Capsule with Felodipine may decrease the blood levels of Felodipine, which may make Felodipine less effective in treating your condition.

How to manage the interaction:
Although taking Enzamide 40mg Capsule and Felodipine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking St. John's Wort products during Enzamide 40mg Capsule treatment may lead to decrease in the effectiveness of Enzamide 40mg Capsule. Avoid St. John's Wort products during Enzamide 40mg Capsule treatment

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Enzamide 40mg Capsule Substitute

Substitutes safety advice
  • Obnyx Capsule 4's

    by AYUR

    192.60per tablet
  • Azel 40 mg Capsule 28's

    by AYUR

    254.79per tablet
  • Xylutide 40 Softgel Cap 4'S

    by Others

    250.43per tablet
  • Adleap 40 mg Capsule 28's

    by Others

    140.29per tablet
  • Glenza 40 mg Capsule 28's

    by AYUR

    172.78per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Enzamide 40mg Capsule .

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Pregnancy

Unsafe

Enzalutamide is only for use in men. Women should not take this medication.

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Breast Feeding

Unsafe

Enzalutamide is only for use in men. Women should not take this medication.

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Driving

Caution

Enzamide 40mg Capsule may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Consult your doctor

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Consult your doctor

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Caution

The safety and effectiveness of Enzamide 40mg Capsule in pediatric patients have not been established.

FAQs

Enzamide 40mg Capsule is used to treat prostate cancer in men.

Most prostate cancers require testosterone to grow. Enzamide 40mg Capsule contains Enzalutamide, which blocks testosterone, a hormone, from reaching prostate cancer cells. Thus, Enzamide 40mg Capsule can slow the cancer's growth and cause it to shrink.

Enzamide 40mg Capsule is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.

In some cases, Enzamide 40mg Capsule may cause decreased fertility in men. However, you should not assume that your female partner cannot become pregnant. Please discuss with your doctor if you have any concerns.

Enzalutamide, a prostate cancer medication, is used to treat prostate cancer.

Seizures may occur in patients receiving Enzamide 40mg Capsule . So, patients who have had a seizure, please inform your doctor about your condition. Your doctor may monitor your condition closely.

Yes, Enzalutamide was generally a well-tolerated medication. Take Enzamide 40mg Capsule pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Enzamide 40mg Capsule unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Enzamide 40mg Capsule therapy or adjust your Enzamide 40mg Capsule dose.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ENZ0135

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