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  3. Espogen 10000 IU Injection 1 ml

Espogen 10000 IU Injection 1 ml, Pack of 1 INJECTION
Espogen 10000 IU Injection 1 ml, Pack of 1 INJECTION
Espogen 10000 IU Injection 1 ml, Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Espogen 10000 IU Injection 1 ml is used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, and bone marrow disorders. This medicine works by stimulating the bone marrow to produce more red blood cells, thereby correcting any low blood counts and anaemia. You may experience common side effects like vomiting, diarrhoea, fever, and nasal congestion.

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Composition :

RECOMBINANT HUMAN ERYTHROPOIETIN ALFA-10000IU

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Espogen 10000 IU Injection 1 ml

Espogen 10000 IU Injection 1 ml belongs to the group of hormones used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, bone marrow disorders, and those due to undergo major bone surgery. Anaemia refers to low blood counts due to a deficiency of the blood component haemoglobin, resulting in a reduced oxygen-carrying capacity of the blood.

Espogen 10000 IU Injection 1 ml contains Recombinant Human Erythropoietin Alfa, which works by stimulating the bone marrow to produce more red blood cells, thereby correcting low blood counts and anaemia.

In some cases, Espogen 10000 IU Injection 1 ml may cause specific common side effects such as vomiting, diarrhoea, fever, and nasal congestion. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects consistently.

Please inform the doctor of your detailed medical history, including hypertension, heart disease, heart attack, stroke, epilepsy, cancer, liver disease, thromboembolism, porphyria and/or pure red cell aplasia (where the bone marrow cannot produce enough RBCs). Consult your doctor before taking Espogen 10000 IU Injection 1 ml during pregnancy and nursing. Store this medicine at 2°C-8°C. Do not freeze.

Uses of Espogen 10000 IU Injection 1 ml

Espogen 10000 IU Injection 1 ml is used to treat anemia caused by chronic kidney illness, cancer, and HIV infection. It is also used in perioperative care for some surgical patients.

Directions for Use

Espogen 10000 IU Injection 1 ml will be administered by a healthcare professional. In some cases, depending on the need, you may have to self-inject Espogen 10000 IU Injection 1 ml. Do not self-inject without proper training. After an initial treatment, your doctor/nurse may train you on administering the injection.

Medicinal Benefits

Espogen 10000 IU Injection 1 ml is a blood hormone. It contains Recombinant Human Erythropoietin Alfa used to treat anaemia caused by chronic diseases and anaemia related to kidney disease, cancers, bone marrow disorders, chemotherapy, children and adults on dialysis, and in those due to undergo major bone surgery. Espogen 10000 IU Injection 1 ml stimulates the bone marrow to produce more red blood cells. In addition, it also corrects any dysregulated erythropoiesis (RBC formation) and remedies the formation of any defunct precursors of RBC’s, paving the way for healthy red blood cell production. Clinically, Espogen 10000 IU Injection 1 ml causes a direct increase in haemoglobin values and reduces the rates and requirement of blood transfusion.

How Espogen 10000 IU Injection 1 ml Works

Espogen 10000 IU Injection 1 ml contains Recombinant Human Erythropoietin Alfa that works by stimulating the bone marrow to produce more red blood cells, thereby correcting any low blood counts and anaemia.

Storage

Store in a cool and dry place away from sunlight
Side effects of Espogen 10000 IU Injection 1 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.

What if I have taken an overdose of Espogen 10000 IU Injection 1 ml

Overdose of Espogen 10000 IU Injection 1 ml increases blood viscosity and the risk of thrombosis by raising haemoglobin levels to dangerously high levels. Seek immediate medical help if you get an overdose of this medicine.

Drug Warnings

Inform the doctor if you have an allergy to any of its components. Proceed with caution in case of a latex allergy. Please inform the doctor of your detailed medical history, including hypertension, heart disease, myocardial infarction, stroke, epilepsy, head and neck cancers, liver disease, thromboembolism, porphyria and/or pure red cell aplasia (where the bone marrow cannot produce enough RBCs). Inform your doctor of any medicines you may be taking especially if you are on any immunosuppressants, blood thinners or blood stimulants. Please consult your doctor before taking Espogen 10000 IU Injection 1 ml during pregnancy and nursing.

Drug-Drug Interactions

verifiedApollotooltip
ErythropoietinLenalidomide
Severe
ErythropoietinPomalidomide
Severe

Drug-Drug Interactions

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ErythropoietinLenalidomide
Severe
How does the drug interact with Espogen 10000 IU Injection 1 ml:
Combining Espogen 10000 IU Injection 1 ml with Lenalidomide can increase the risk of Thrombosis(formation of a blood clot ).

How to manage the interaction:
Although there is an interaction between Espogen 10000 IU Injection 1 ml and Lenalidomide, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ErythropoietinPomalidomide
Severe
How does the drug interact with Espogen 10000 IU Injection 1 ml:
Pomalidomide can cause serious blood clots and taking it alongside Espogen 10000 IU Injection 1 ml may enhance the risk.

How to manage the interaction:
Co-administration of Espogen 10000 IU Injection 1 ml with Pomalidomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ErythropoietinCarfilzomib
Severe
How does the drug interact with Espogen 10000 IU Injection 1 ml:
Carfilzomib can cause serious blood clots and taking it alongside Espogen 10000 IU Injection 1 ml may enhance the risk.

How to manage the interaction:
Co-administration of Espogen 10000 IU Injection 1 ml with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ErythropoietinThalidomide
Severe
How does the drug interact with Espogen 10000 IU Injection 1 ml:
Taking thalidomide with Espogen 10000 IU Injection 1 ml may increase the risk or severity of thromboembolism(a circulating blood clot that gets stuck and causes an obstruction).

How to manage the interaction:
Although taking Espogen 10000 IU Injection 1 ml and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • As nausea and vomiting may occur using Espogen 10000 IU Injection 1 ml, make sure to take it on light, small meals. 
  • To promote blood production, eat red fruits and vegetables, such as apples, pomegranates, dry fruits, beans, and nuts.
  • Avoid caffeine and alcohol as these can precipitate bleeding.
  • Take care of your mental health. Stress is a huge factor that can cause excessive bleeding. Make sure you meditate daily in the morning.
  • Yoga has also proven very effective in preventing excessive blood loss. The butterfly pose is one of the best poses for treating heavy periods.
  • Make sure you drink a lot of water and keep yourself hydrated. Fluid intake helps flush out toxins.

Habit Forming

No

Therapeutic Class

BLOOD DERIVATIVES

Espogen 10000 IU Injection 1 ml Substitute

Substitutes safety advice

  • Epofit 10000IU Injection 1 ml

    by Others

    ₹1984.50per tablet

  • Anfoe 10000IU Injection 1 ml

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    ₹1983.60per tablet

  • TRANSFER 10000IU INJECTION

    by Others

    ₹1983.60per tablet

  • Zyrop 10000 Injection 1's

    by Others

    ₹1984.50per tablet

  • Repomia 10000 Injection 1 ml

    by AYUR

    ₹1936.00per tablet

Product Substitutes

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Alcohol

Caution

There is not enough literature to explain the effects of alcohol. Consult your doctor if you have any concerns.

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Pregnancy

Caution

If you are pregnant or planning to become pregnant, inform your doctor. Your doctor will weigh the benefits against the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Espogen 10000 IU Injection 1 ml; your doctor will decide whether breastfeeding mothers can use Espogen 10000 IU Injection 1 ml or not.

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Driving

Caution

It's unclear whether Espogen 10000 IU Injection 1 ml affects driving abilities, so don't drive or operate machinery if you're having trouble concentrating or reacting.

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Liver

Caution

Espogen 10000 IU Injection 1 ml should be used with caution in patients suffering from liver diseases. Please inform your doctor before receiving it.

bannner image

Kidney

Caution

Espogen 10000 IU Injection 1 ml should be used with caution in patients suffering from kidney diseases. Please inform your doctor before receiving it.

bannner image

Children

Safe if prescribed

Espogen 10000 IU Injection 1 ml can be used in children in prescribed paediatric doses.

FAQs

Espogen 10000 IU Injection 1 ml belongs to the group of hormones used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, bone marrow disorders and in those due to undergo major bone surgery.

Espogen 10000 IU Injection 1 ml works by stimulating the bone marrow to produce healthy red blood cells (RBC’s) and thus enhances blood production.

Consult your doctor before taking iron supplements along with Espogen 10000 IU Injection 1 ml as they might increase the effectiveness of Espogen 10000 IU Injection 1 ml when taken together.

Espogen 10000 IU Injection 1 ml might affect other treatments or tests. Therefore, inform the doctor/lab assistant that you are taking Espogen 10000 IU Injection 1 ml.

Not commonly. However, cases of Steven Johnson’s syndrome and Toxic Epidermal Necrosis (TEN), have been reported in rare instances. Consult your doctor immediately if you notice symptoms such as reddish-circular patches, skin peeling, fever, flu, ulcers of throat, mouth, nose, eyes or genitals.

Espogen 10000 IU Injection 1 ml may cause blood clots (deep vein thrombosis and embolism). Consult your doctor if you experience symptoms such as breathlessness, chest pain, painful swelling and redness in the legs.

The common side effects of Espogen 10000 IU Injection 1 ml may include vomiting, diarrhoea, fever, and nasal congestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.

Espogen 10000 IU Injection 1 ml contains Recombinant Human Erythropoietin Alfa. A hormone medication that stimulates the bone marrow to produce more red blood cells, correcting low blood counts and anaemia.

Don't stop taking your medication just because you're feeling better! This is a crucial moment in your recovery. Stopping too soon can lead to incomplete recovery and the return of symptoms. Instead, report your progress to your doctor and follow their advice. They will guide you on how to safely taper off the medication, if necessary, monitor for any potential side effects, and ensure the infection is fully cleared.

Espogen 10000 IU Injection 1 ml is usually given to you by a healthcare professional through an Intravenous(veins). In some cases, you may need to go to a local clinic or learn to self-inject, but only after proper training from a doctor or nurse.

You can store Espogen 10000 IU Injection 1 ml in the refrigerator or a cool, dry place away from sunlight. Do not freeze. Use at room temperature only.

Store Espogen 10000 IU Injection 1 ml in a refrigerator or in a cool, dry place away from sunlight. Keep it out of reach of children. Do not freeze it.

Taking more than the prescribed dose doesn't provide extra relief; instead, it may increase the risk of adverse effects, potentially harming your health.

Don't use Espogen 10000 IU Injection 1 ml if the solution is expired, frozen, or allergic to it. It's also not recommended for those with hypersensitivity disorders, thromboembolism, and red cell aplasia. Pregnant or breastfeeding women or children unless the doctor suggests it. Always consult your doctor before using.

Espogen 10000 IU Injection 1 ml can be used in children under a doctor's guidance and in prescribed pediatric doses.

Espogen 10000 IU Injection 1 ml may increase blood pressure or worsen existing high blood pressure, especially in patients with kidney failure, due to the rapid increase in red blood cells. Inform your doctor beforehand if you have any blood pressure issues. Your doctor will adjust the dose if the benefits outweigh the risks.

Country of origin

INDIA

Manufacturer/Marketer address

LG Life Sciences India Pvt. Ltd., Unit No. 201, 2nd Floor, BPTP Park Centra, Sec 30, Gurgaon 122001, Haryana, India
Other Info - ESP0003

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Doctor imageDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 11, 2025 | 12:04 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.webmd.com/drugs/2/drug-1023/epoetin-alfa-injection/details
  2. https://www.medicines.org.uk/emc/files/pil.3442.pdf
  3. https://www.sciencedirect.com/topics/medicine-and-dentistry/recombinant-erythropoietin
  4. https://pubmed.ncbi.nlm.nih.gov/12735213/
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