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  3. Estofol 2 mg Tablet 28's

Estofol 2 mg Tablet 28's, Pack of 28 TabletS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Estofol 2 mg Tablet is an hormone medicine used in the treatment of post-menopausal symptoms, osteoporosis, hypoestrogenism and advanced androgen-dependent carcinoma of the prostate. This medicine contains estradiol, which works by enhancing the lowered levels of the sex hormone oestrogen in the peri or post-menopausal female body, thus helps reduce symptoms of menopause such as vaginal dryness, hot flashes (hot face, neck and chest) and weak bones.
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Composition :

ESTRADIOL VALERATE-2MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Estofol 2 mg Tablet

Estofol 2 mg Tablet is a hormone replacement therapy used in the treatment of the symptoms of menopause, osteoporosis, hypoestrogenism due to hypogonadism, and advanced androgen-dependent carcinoma of the prostate. Menopause is the stopping of a woman’s period for life and is marked after an entire span of 12 months without periods.

Estofol 2 mg Tablet is composed of Estradiol valerate that works by enhancing the lowered levels of the sex hormone oestrogen in the peri or post-menopausal female body. This helps combat the various symptoms of menopause such as vaginal dryness, hot flashes (hot face, neck and chest) and weak bones. 

Take Estofol 2 mg Tablet as prescribed. In some cases, Estofol 2 mg Tablet may cause certain common side effects such as nausea, vomiting, breast soreness, headache and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.

Keep your doctor informed if you are allergic to any medicines. Discuss with the doctor if you have/had cardiovascular disease, thrombotic disorders, pulmonary embolism, mental health disorders, liver disease, gall bladder disease, anaemia, bleeding disorders, or breast/uterine/cervical cancer. Estofol 2 mg Tablet is intended for post-menopausal women; therefore, do not take Estofol 2 mg Tablet if you are pregnant or breastfeeding.

Uses of Estofol 2 mg Tablet

Treatment of Post-menopausal symptoms, Osteoporosis, Hypoestrogenism and Advanced androgen-dependent carcinoma of the prostate

Directions for Use

• Estofol 2 mg Tablet can be taken with or without food or as advised by the doctor. • Follow your doctor's instructions regarding dosage and timing to ensure optimal effectiveness. • Swallow Estofol 2 mg Tablet as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

Estofol 2 mg Tablet is a hormone replacement therapy (HRT) used in the treatment of the symptoms of menopause, osteoporosis, hypoestrogenism due to hypogonadism, and advanced androgen-dependent carcinoma of the prostate. Estofol 2 mg Tablet helps in the synthesis and maintenance of sex hormone oestrogen in the body, by acting as its precursor. It acts directly on plasma membrane receptors and promotes the conversion of oestradiol to its most potent counterpart, thereby enhancing the body’s levels of oestrogen and helping fight the symptoms of menopause.

How Estofol 2 mg Tablet Works

Estofol 2 mg Tablet is composed of Estradiol valerate that works by enhancing the lowered levels of the sex hormone oestrogen in the peri or post-menopausal female body. This helps combat the various symptoms of menopause such as vaginal dryness, hot flashes (hot face, neck and chest) and weak bones.

Storage

Store at 25°C. Protect from direct sunlight. Keep out of reach of children.
Side effects of Estofol 2 mg Tablet
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Estofol 2 mg Tablet

An overdose of Estofol 2 mg Tablet can cause symptoms such as bloating, nausea, vomiting, water retention, weight gain, breast tenderness, vaginal discharge, heavy legs, and cramping in the legs. Hence, take it only in prescribed doses.

Drug Warnings

Estofol 2 mg Tablet should not be used in case of any known allergy to any of the components. Inform your doctor if you have/had arterial or thrombotic disorders, cardiovascular health disorders, porphyria, anaemia, hypertension, diabetes, asthma, epilepsy, bleeding disorders, liver problem, kidney problem, depression, gallbladder disease, breast/uterine/cervical cancer or any hormone-sensitive cancer. Estofol 2 mg Tablet is intended for use in postmenopausal women, do not take Estofol 2 mg Tablet  if you are pregnant or breastfeeding. Estofol 2 mg Tablet should be used with caution if you are on any anti-epileptic, anti-tuberculosis, anti-hypertensive, cardiac, antifungal, antibiotic, anti-depressant or anti-retroviral therapy. Women with a tendency for chloasma/melasma (skin condition commonly seen in middle-aged women), should avoid sun exposure after taking Estofol 2 mg Tablet . Women with a history of angioedema should exercise caution while taking Estofol 2 mg Tablet as it may worsen the angioedema.

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
EstradiolThalidomide
Severe

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
How does the drug interact with Estofol 2 mg Tablet:
When Etodolac is taken with Bivalirudin, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Bivalirudin with Estofol 2 mg Tablet can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.
EstradiolThalidomide
Severe
How does the drug interact with Estofol 2 mg Tablet:
Taking thalidomide together with Estofol 2 mg Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Estofol 2 mg Tablet and thalidomide together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
EstradiolPomalidomide
Severe
How does the drug interact with Estofol 2 mg Tablet:
Co-administration of Estofol 2 mg Tablet and Pomalidomide can increase the risk of serious blood clots.

How to manage the interaction:
There may be a possibility of interaction between Estofol 2 mg Tablet and Pomalidomide, but it can be taken if prescribed by a doctor. However, if you experience symptoms like chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EstradiolTranexamic acid
Severe
How does the drug interact with Estofol 2 mg Tablet:
Co-administration of Estofol 2 mg Tablet with Tranexamic acid can increase the risk of blood clots.

How to manage the interaction:
Taking Estofol 2 mg Tablet with Tranexamic acid can lead to an interaction; however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolExemestane
Severe
How does the drug interact with Estofol 2 mg Tablet:
Using Estofol 2 mg Tablet with Exemestane may interfere with Exemestane's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Exemestane and Estofol 2 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EstradiolClindamycin
Severe
How does the drug interact with Estofol 2 mg Tablet:
When taken in combination, clindamycin can lower the amount or action of Estofol 2 mg Tablet.

How to manage the interaction:
Co-administration of Estofol 2 mg Tablet with Clindamycin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolCarfilzomib
Severe
How does the drug interact with Estofol 2 mg Tablet:
Carfilzomib can cause serious blood clots and taking it alongside Estofol 2 mg Tablet may enhance the risk.

How to manage the interaction:
Co-administration of Estofol 2 mg Tablet with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolLetrozole
Severe
How does the drug interact with Estofol 2 mg Tablet:
Letrozole may have a negative effect when used with Estofol 2 mg Tablet, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrozole and Estofol 2 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EstradiolLenalidomide
Severe
How does the drug interact with Estofol 2 mg Tablet:
Coadministration of Estofol 2 mg Tablet and Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Estofol 2 mg Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolAnastrozole
Severe
How does the drug interact with Estofol 2 mg Tablet:
Estofol 2 mg Tablet may interfere with anastrozole's function and make it less effective in treating your condition.

How to manage the interaction:
Co-administration of Anastrozole with Estofol 2 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • As nausea and vomiting may occur with the use of Estofol 2 mg Tablet , make sure to take it on light, small meals. 
  • Avoid grapefruit juice while taking Estofol 2 mg Tablet as this may interact with Estofol 2 mg Tablet and affect its absorption. 
  • Avoid smoking as it increases the risk of stroke. 
  • Keep your meals balanced and invest in a healthy diet to avoid any cardiovascular problems. 
  • Load up on meats, fatty fish, oranges and strawberries, sesame seeds, soybean and canola oil and pistachios to enhance anti-oxidation and overall health during menopause.

Habit Forming

No

Therapeutic Class

HORMONES

Estofol 2 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Caution should be exercised while consuming alcohol with Estofol 2 mg Tablet as there may be an interaction.

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Pregnancy

Unsafe

Estofol 2 mg Tablet is indicated for use only in menopausal conditions and is not recommended for use during pregnancy.

bannner image

Breast Feeding

Unsafe

Estofol 2 mg Tablet is indicated for use only in menopausal conditions and is not recommended for use during breastfeeding.

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Driving

Safe if prescribed

Estofol 2 mg Tablet does not normally affect your ability to drive.

bannner image

Liver

Caution

Take Estofol 2 mg Tablet with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Estofol 2 mg Tablet should be used with caution in patients suffering from kidney disease. Please consult your doctor in case of any concerns.

bannner image

Children

Unsafe

Estofol 2 mg Tablet is not meant for use by children or adolescents.

Have a query?

FAQs

Estofol 2 mg Tablet is a hormone replacement therapy used in the treatment of the symptoms of menopause, osteoporosis, hypoestrogenism due to hypogonadism, and advanced androgen-dependent carcinoma of the prostate.

Estofol 2 mg Tablet works by enhancing the levels of the sex hormone oestrogen in the female body. Thereby, helps treat menopausal symptoms.

Yes, Estofol 2 mg Tablet is very effective in combating hot flashes in menopausal women.

Estofol 2 mg Tablet helps with various symptoms of menopause including osteoporosis and weakened bones. However, you may need Vitamin D supplements to address this issue. Discuss with your physician.

You may be advised to stop taking Estofol 2 mg Tablet about 4 to 6 weeks before surgery to decrease the risk of a blood clot. Therefore, inform your doctor that you are taking Estofol 2 mg Tablet before undergoing any surgery.

Estofol 2 mg Tablet is not a contraceptive. Estofol 2 mg Tablet is a hormone replacement therapy. Therefore, if you are less than 50 years old or if it is less than 12 months since your last period, you are advised to use additional contraceptive measures to avoid pregnancy. However, discuss with a doctor if you have any concerns regarding this.

Estofol 2 mg Tablet comprises the active ingredient Estradiol valerate, which is used as a hormone therapy for menopausal symptoms and hypoestrogenism (low estrogen levels).

If you miss a dose of Estofol 2 mg Tablet , take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the usual time. Do not take two doses at once to make up for a missed dose. Always follow your doctor's instructions for dosing.

Estofol 2 mg Tablet may cause common side effects such as nausea, vomiting, breast soreness, headache, and bloating. Most of these side effects do not require medical attention and will resolve on their own over time. However, please consult your doctor if these side effects persist or become bothersome.

For estrogen deficiency, treatments may include hormone replacement therapy (HRT), such as Estofol 2 mg Tablet , which can be prescribed by your doctor. Other options include non-hormonal medications, lifestyle changes, and dietary adjustments. It is important to consult with your doctor to determine the most suitable treatment based on your specific health condition.

Estofol 2 mg Tablet should not be taken by individuals who are allergic to any of its ingredients. It is also not recommended for people with a history of certain health conditions, such as breast cancer, abnormal genital bleeding, blood clots, stroke, myocardial infarction, or liver disease. Always consult your doctor before starting this medication to ensure it is safe for you. Estofol 2 mg Tablet is intended for use in postmenopausal women and should not be taken if you are pregnant or breastfeeding.

Estofol 2 mg Tablet , a form of estrogen used in hormone therapy, may cause weight changes in some individuals, but weight gain is not a guaranteed side effect. If you notice significant changes in your weight, please consult your doctor.

Estofol 2 mg Tablet should be taken exactly as directed by your doctor. It is usually taken orally, with or without food, at the same time each day. Swallow the medication as a whole with a glass of water. Do not crush, chew, or break it.

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - EST0204

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:56 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.1417.pdf
  2. https://www.webmd.com/drugs/2/drug-6787/estradiol-valerate-intramuscular/details#:~:text=This%20medication%20is%20a%20female,the%20body%20making%20less%20estrogen
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/009402s052lbl.pdf

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