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  3. Ethide 250 Tablet 12's

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Ethide 250 Tablet 12's, Pack of 12 TabletS
Ethide 250 Tablet 12's, Pack of 12 TabletS
Ethide 250 Tablet 12's, Pack of 12 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Ethide 250 Tablet is an antibiotic used to treat tuberculosis (TB). It is used in combination with other tuberculosis medicines. It contains Ethionamide, which kills or prevents the growth of bacteria. It may cause common side effects such as nausea, vomiting, stomach pain, diarrhoea, increased saliva, strange metallic taste, or mouth sores.
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Composition :

ETHIONAMIDE-250MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Ethide 250 Tablet

Ethide 250 Tablet belongs to the group of medicines called antibiotic drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs. Ethide 250 Tablet should not be used alone and must be given in combination with other tuberculosis medications. Ethide 250 Tablet does not work against infections caused by the virus, including cold and flu.

Ethide 250 Tablet consists of a medicine called 'Ethionamide' that works by inhibiting bacteria's growth that causes tuberculosis (Mycobacterium tuberculosis).

The dose and duration of Ethide 250 Tablet can vary depending on your condition and the severity of the infection. In some cases, you may experience common side effects such as nausea, vomiting, abdominal pain, diarrhoea, increased saliva, strange metallic taste, or sores in the mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not stop taking Ethide 250 Tablet despite symptomatic relief. Treat your condition effectually, and continue taking Ethide 250 Tablet for as long as it has been prescribed. Take Ethide 250 Tablet with caution if you have diabetes. Consult your doctor before taking Ethide 250 Tablet if you are pregnant. Avoid breastfeeding while taking Ethide 250 Tablet as it passes into breast milk. Ethide 250 Tablet may rarely cause dizziness, and vision problems, so drive with caution if you experience these signs. Avoid consuming alcohol with Ethide 250 Tablet as it might lead to liver problems or mental/mood changes. Do not take Ethide 250 Tablet if you have severe liver disease. Inform your doctor immediately if you experience/notice confusion, seizure, dark urine, or clay-coloured stools after taking Ethide 250 Tablet .

Uses of Ethide 250 Tablet

Ethide 250 Tablet used in the treatment of Tuberculosis (TB). The detailed use of Ethide 250 Tablet is as follows:<br/>• Treatment of Tuberculosis (TB): Ethide 250 Tablet is used to treat tuberculosis (TB) by targeting active infections, eliminating TB-causing bacteria, addressing resistant strains, and preventing disease progression and transmission.<br/>

Directions for Use

• Take Ethide 250 Tablet with or without food as advised by your doctor.• Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.• Swallow Ethide 250 Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Ethide 250 Tablet contains ‘Ethionamide’ that works by inactivating a bacterial genetic material that allows TB bacteria (Mycobacterium tuberculosis) to make a copy of its protein for further growth inside the host cell (human). Ethionamide is indicated in treating active tuberculosis in patients with Mycobacterium tuberculosis infection resistant to rifampin or isoniazid.

How Ethide 250 Tablet Works

Ethide 250 Tablet consists of a medicine called 'Ethionamide' that works by inhibiting bacteria's growth that causes tuberculosis (Mycobacterium tuberculosis).

Storage

Keep Ethide 250 Tablet out of the sight and reach of children.
Side effects of Ethide 250 Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Regularly brush your tongue and teeth to prevent Excessive Saliva Production.
  • Avoid eating foods high in sugar or acid since these foods might increase saliva production, which increases the Excessive Saliva Production.
  • Keep your head up straight and maintain proper posture to prevent saliva from collecting in your mouth.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.
  • Frequent flossing and brushing can help remove bacteria and debris that can give your teeth a metallic taste.
  • The metallic flavor may be caused by a zinc deficiency. Eat foods like meat, chicken, and oysters that are high in zinc.
  • Reducing the intake of foods with strong aromas, like onions and garlic, as they may intensify the taste of metallic substances.
  • Avoid smoking and tobacco products as they may intensify the metallic flavor.

What if I have taken an overdose of Ethide 250 Tablet

Do not take more than the prescribed dose of Ethide 250 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Before starting Ethide 250 Tablet , please inform your doctor if you have a medical history, especially of: liver disease, underactive thyroid (hypothyroidism), kidney disease, or eye problems (such as optic neuritis and cataracts). Take Ethide 250 Tablet with caution if you have diabetes. Ethide 250 Tablet may lower your blood sugar levels. Also, check your blood sugar level regularly as directed by your doctor. Consult your doctor before taking Ethide 250 Tablet if you are pregnant. This medication is not recommended for use in pregnant women. Avoid breastfeeding while taking Ethide 250 Tablet as it passes into breast milk. Ethide 250 Tablet may cause dizziness, and vision problems, so drive with caution. Avoid consuming alcohol with Ethide 250 Tablet as it might lead to liver problems or mental/mood changes.

Drug-Drug Interactions

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EthionamideLeflunomide
Severe
EthionamideKetoconazole
Severe

Drug-Drug Interactions

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EthionamideLeflunomide
Severe
How does the drug interact with Ethide 250 Tablet:
Coadministration of leflunomide with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although taking Ethide 250 Tablet with Leflunomide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.
EthionamideKetoconazole
Severe
How does the drug interact with Ethide 250 Tablet:
Coadministration of Ketoconazole and Ethide 250 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ethide 250 Tablet with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.
EthionamideMipomersen
Severe
How does the drug interact with Ethide 250 Tablet:
Taking mipomersen with Ethide 250 Tablet can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Ethide 250 Tablet and Mipomersen, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience fever, joint pain, swelling, skin rash, vomiting, abdominal pain, or dark urine. Do not stop using any medications without talking to your doctor.
EthionamideLomitapide
Severe
How does the drug interact with Ethide 250 Tablet:
Coadministration of lomitapide with Ethide 250 Tablet can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Ethide 250 Tablet and Lomitapide, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain, swelling, skin rash, itching, bleeding, tiredness, stomach ache, dark urine. Do not stop using any medications without a doctor's advice.
EthionamideEthanol
Severe
How does the drug interact with Ethide 250 Tablet:
Excessive alcohol use while taking Ethide 250 Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking Ethide 250 Tablet and Ethanol together can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience hallucinations(seeing & hearing things that do not exist) and abnormal thinking. Do not stop using any medications without consulting your doctor.
EthionamideRifampicin
Severe
How does the drug interact with Ethide 250 Tablet:
Taking rifampicin with Ethide 250 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Ethide 250 Tablet and Rifampicin, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, joint pain, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.
EthionamideTeriflunomide
Severe
How does the drug interact with Ethide 250 Tablet:
Taking Teriflunomide with Ethide 250 Tablet can increase the risk of liver problems.

How to manage the interaction:
Taking Ethide 250 Tablet with Teriflunomide together can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms - fever, joint pain, swelling, skin rash, vomiting, abdominal pain, dark-coloured urine - immediately contact your doctor. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help relieve a cough.
  • Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • To help prevent certain side effects (such as nerve problems) from this medication, your doctor may advise you to take vitamin B6 (pyridoxine).
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Ethide 250 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption while taking Ethide 250 Tablet as it could lead to increased dizziness or mental/mood changes.

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Pregnancy

Caution

Pregnancy Category C: There are no adequate and well-controlled studies in pregnant women. It is unknown whether Ethide 250 Tablet can cause fetal harm when administered to a pregnant woman. It should not be used in pregnant women.

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Breast Feeding

Unsafe

Ethide 250 Tablet may pass into breast milk. Do not breastfeed while taking Ethide 250 Tablet .

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Driving

Unsafe

Ethide 250 Tablet may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

bannner image

Liver

Unsafe

Do not use ethionamide if you have severe liver disease. consult your doctor if you have any concerns.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or kidney impairment/kidney disease before taking Ethide 250 Tablet .

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Children

Caution

Ethide 250 Tablet should not be used in children without a doctor's advice.

Have a query?

FAQs

Ethide 250 Tablet is used to treat tuberculosis.

Ethide 250 Tablet is an antibiotic which works by inhibiting the synthesis of mycolic acid (a saturated fatty acid found in the bacterial cell wall), thereby stopping the synthesis of the bacterial cell wall. Eventually, this leads to bacterial cell wall disruption. Ethionamide may have bacteriostatic or bactericidal in action. Ethionamide indicated in the treatment of active tuberculosis in patients with Mycobacterium tuberculosis infection resistant to rifampin or isoniazid.

Do not stop taking Ethide 250 Tablet despite symptomatic relief. Treat your condition effectually, continue taking Ethide 250 Tablet for as long as it has been prescribed for you.

Ethide 250 Tablet might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking Ethide 250 Tablet . Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate contraception method.

Ethide 250 Tablet might affect vision rarely. It may cause blurred/decreased/double vision, colour blindness, or eye pain. Inform your doctor right away if you notice/experience any of these serious side effects. Do not drive if you experience any of these symptoms.

Ethionamide might interfere with live bacterial vaccines and cause them not to work as well. Do not have any immunizations/vaccinations while on this medication.

Yes, it is safe to use other tuberculosis medications with Ethide 250 Tablet if prescribed by the doctor.

Ethide 250 Tablet should not be given to children under 12 years of age as its safety and effectiveness were not established. Consult the doctor if you have any concerns.

Ethide 250 Tablet belongs to a group of medications called antibiotics. It treats tuberculosis, an infectious disease that primarily affects the lungs. It works by inhibiting the growth of the bacteria responsible for tuberculosis (Mycobacterium tuberculosis).

Ethide 250 Tablet contains ethionamide, which is classified as a second-line drug because it is used to treat tuberculosis (TB) when first-line drugs are ineffective, poorly tolerated, or result in resistance. These medications are generally reserved for more complex or drug-resistant TB cases.

Avoid breastfeeding while taking Ethide 250 Tablet as it passes into breast milk. Do not drink alcohol while taking Ethide 250 Tablet , as it may increase the risk of liver issues or cause changes in mood and mental state. Drive cautiously while taking Ethide 250 Tablet as it may cause dizziness and vision problems. If you have diabetes, check your blood sugar levels carefully. the doctor may suggest regular blood tests to monitor your liver and thyroid function, as well as frequent vision tests while taking Ethide 250 Tablet .

Ethide 250 Tablet should be taken for as long as it has been prescribed by the doctor. The dose and duration will be determined by the doctor based on your medical condition.

The doctor may suggest regular blood tests to monitor your liver and thyroid function, your health condition and the effectiveness of the medicine.

Contact the doctor immediately if you experience symptoms of liver toxicity like nausea, loss of appetite, dark urine, pale stools, jaundice (yellowing of the skin or eyes), or pain and tenderness in the upper right abdomen.

The doctor may recommend taking vitamin B6 (pyridoxine) with Ethide 250 Tablet , to help prevent certain side effects, such as nerve problems.

Ethide 250 Tablet may cause aggression as a side effect in some individuals. These symptoms may be related to Ethide 250 Tablet or other TB medications. It is important to discuss these changes with their family or doctor for proper management and care.

The side effects of Ethide 250 Tablet include diarrhoea, abdominal pain, nausea, vomiting, increased saliva, strange metallic taste, or sores in the mouth. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - ETH0265

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:46 AM IST

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Reference

  1. https://www.mayoclinic.org/drugs-supplements/ethionamide-oral-route/description/drg-20063736
  2. https://pubchem.ncbi.nlm.nih.gov/compound/Ethionamide#section=CAMEO-Chemicals
  3. https://www.drugs.com/mtm/ethionamide.html
  4. https://www.ncbi.nlm.nih.gov/books/NBK247426/
  5. https://www.webmd.com/drugs/2/drug-8779/ethionamide-oral/details
  6. https://www.pdr.net/drug-summary/Trecator-ethionamide-1952

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