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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Febuxostat Capsule is used to prevent severe gout attacks or flares. It contains Febuxostat, which reduces the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. It may cause common side effects such as nausea, rash, dizziness, diarrhoea, pain, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), and localised swelling due to retention of fluids in tissues (oedema). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

FEBUXOSTAT-40MG

Manufacturer/Marketer :

S N Medi Health Care

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Febuxostat Capsule

Febuxostat Capsule is used to prevent severe gout attacks or flares. Gout is a chronic condition caused by the deposition of uric acid crystals in the joints. It is characterised by intense pain and swelling at the affected joints.

Febuxostat Capsule contains febuxostat that works by inhibiting the enzyme xanthine oxidase (an enzyme that helps your body make uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints.

Not everyone who is taking Febuxostat Capsule will get these side effects. The common side effects of Febuxostat Capsule include nausea, rash, dizziness, diarrhoea, pain, and localised swelling due to fluid retention in tissues (oedema). Most of these side effects of Febuxostat Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Take this medication by mouth with or without food as directed by your doctor. The dosage is based on your medical condition and response to treatment. To help you remember, take it at the same time each day. Tell your doctor if your condition does not improve or worsens (if your blood sugar is too high or too low).

Inform your doctor if you are allergic to Febuxostat Capsule , have a heart problem (Febuxostat Capsule may cause heart problems that can lead to a heart attack), or have kidney/liver disease.. Do not stop taking a Febuxostat Capsule of your own. Stopping it may worsen your condition and increase the risk of increased uric acid levels and future gout attacks. The safety and effectiveness of children under 18 years of age have not been established, so Febuxostat Capsule should not be given to them. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Febuxostat Capsule .

Uses of Febuxostat Capsule

Febuxostat Capsule is used to treat severe gout and prevent gout attacks. The detailed uses of Febuxostat Capsule are as follows:
• Gout Management: Febuxostat Capsule helps to manage gout by lowering uric acid levels, reducing pain, redness, and swelling in the joints.
• Chronic Kidney Disease Support: Febuxostat Capsule also supports patients with chronic kidney disease by managing uric acid levels, which can help in protecting kidney function.
• Prevention of Gout Attacks: Febuxostat Capsule is also involved in preventing gout attacks by keeping uric acid levels normal, reducing the frequency of painful episodes.
• Uric Acid Nephrolithiasis Prevention: Febuxostat Capsule can prevent uric acid kidney stones by reducing uric acid levels, lowering the risk of related complications.
• Treatment of Tumor Lysis Syndrome: Febuxostat Capsule manages tumor lysis syndrome in chemotherapy patients by preventing high uric acid levels caused by rapid cell breakdown.

Directions for Use

• Febuxostat Capsule can be taken with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication. • Swallow Febuxostat Capsule as a whole with a glass of water. • Do not crush, break, or chew it.

Medicinal Benefits

Febuxostat Capsule is a class of medications called xanthine oxidase inhibitors (enzymes that help your body make uric acid). It works by inhibiting the enzyme xanthine oxidase, thereby reducing the level of uric acid that is made in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Febuxostat Capsule is used to prevent gout attacks or flares.

How Febuxostat Capsule Works

Febuxostat Capsule contains febuxostat. It works by inhibiting the enzyme xanthine oxidase (an enzyme that helps your body make uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Febuxostat Capsule is used to prevent gout attacks or flares.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Febuxostat Capsule

Do not take more than the prescribed dose of Febuxostat Capsule as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Febuxostat Capsule if you are allergic to Febuxostat Capsule , or have heart-related problems, as it increases the risk of a heart attack. Also, inform your doctor if you are allergic to any other medicines. It should be used cautiously in patients with kidney problems and blood disorders. Stopping it may worsen your condition and increase the risk of increased uric acid levels and future gout attacks.

Caution is required before taking Febuxostat Capsule if you are pregnant, planning to become pregnant, or are already breastfeeding. The safety and effectiveness of children under 18 years of age have not been established, so Febuxostat Capsule should not be given to them. Some people experience more gout flare-ups when they start taking Febuxostat Capsule . You should continue taking this drug even if gout flare-ups occur. Your doctor may prescribe a combination therapy to prevent flare-ups when you start Febuxostat Capsule .

Store Febuxostat Capsule at room temperature. You are advised not to chew, crush or break the medicine. Keep the medicine out of reach of children. Do not take more than the recommended dose of medicine, as it can cause undesirable effects. It is always important to check for the expiry of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Mercaptopurine with Febuxostat Capsule can increase the blood levels of mercaptopurine.

How to manage the interaction:
Taking Mercaptopurine with Febuxostat Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Febuxostat Capsule Capsule:
Taking azathioprine and Febuxostat Capsule together can increase the blood levels of azathioprine

How to manage the interaction:
Taking Azathioprine with Febuxostat Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FebuxostatLomitapide
Severe
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Febuxostat Capsule with lomitapide can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat Capsule with Lomitapide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Febuxostat Capsule with ketoconazole can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat Capsule with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Febuxostat Capsule with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat Capsule with Leflunomide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Teriflunomide with Febuxostat Capsule can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat Capsule and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
FebuxostatMipomersen
Severe
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Febuxostat Capsule with Mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Febuxostat Capsule with Mipomersen can result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Turmeric and fish can also help reduce inflammation in the tissue.

  • Please do not go for heavy exercise as it may increase your joint pain and arthritis. Instead, you can do low-impact aerobic movements like walking on a treadmill and swimming. You can also strengthen your muscles by lifting light weights.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use a back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. You can also use a footrest if required.
  • Avoid a high purine-rich diet, including organ meats (kidneys, liver, and sweetbreads) and oily fish (sardines, anchovies, and herring).
  • Limit meat in favour of plant-based proteins like beans and legumes.
  • Eat complex carbohydrates, such as whole-grain bread, fruits, and vegetables, rather than sugary sweets and refined carbohydrates like white bread.
  • Avoid drinking beer and alcoholic beverages, and drink plenty of water or other nonalcoholic beverages.

Habit Forming

No

Therapeutic Class

ANTI- GOUT MEDICATIONS
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Alcohol

Unsafe

You should avoid taking alcohol while taking Febuxostat Capsule because alcohol may affect Febuxostat Capsule effectiveness.

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Pregnancy

Consult your doctor

Febuxostat Capsule should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

There is limited data on how Febuxostat Capsule affects breastfeeding. Please consult your doctor before starting Febuxostat Capsule .

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Driving

Unsafe

Do not drive or operate machinery if you experience sleepiness, blurred vision and numbness or tingling sensation while using Febuxostat Capsule . Seek medical attention if the symptoms persist longer.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver disease. Your doctor will weigh the benefits and any potential risks before prescribing Febuxostat Capsule .

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Kidney

Consult your doctor

Febuxostat Capsule should be used with caution in patients with renal impairment. The doctor may adjust the dose depending on your condition.

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Children

Unsafe

Febuxostat Capsule is not recommended for children below the age of 18 years. The safety and efficacy of Febuxostat Capsule have not been established in children due to limited testing of this drug on children.

Have a query?

FAQs

Febuxostat Capsule is used to prevent severe gout attacks or flares. It prevents the sudden attacks of pain caused by severe gout and decreases pain, swelling, and inflammation.

Febuxostat Capsule is a class of antigout drugs called xanthine oxidase inhibitors. It works by decreasing a high amount of uric acid to the normal level that is made in the body. Febuxostat Capsule is used to prevent gout attacks but not to treat them once they occur.

No, Do not discontinue Febuxostat Capsule without consulting your doctor. To treat your condition effectively, continue taking Febuxostat Capsule for as long as prescribed. If you stop taking Febuxostat Capsule , your uric acid levels will likely remain high and continue to cause gout symptoms.

Febuxostat Capsule is not recommended if you have heart disease; taking Febuxostat Capsule may cause serious heart problems, which can be life-threatening in some cases. So, please consult your doctor before taking the Febuxostat Capsule .

Do not drive or operate machinery if you experience dizziness or drowsiness while using Febuxostat Capsule .

The dose and duration of Febuxostat Capsule depend upon your medical condition. It may take several months before Febuxostat Capsule begins to prevent gout attacks. Do not stop taking Febuxostat Capsule without the advice of your doctor even if you feel better.

It is best taken in the morning. You can take Febuxostat Capsule with or without food. Keep taking Febuxostat Capsule every day, to prevent gout attacks.

Chronic hyperuricemia is a condition in which serum uric acid levels are higher than normal.

Hyperuricemia occurs when the body produces too much uric acid or when the kidneys are unable to excrete it properly.

Side effects of Febuxostat Capsule include nausea, rash, dizziness, diarrhoea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localised swelling due to retention of fluids in tissues (oedema). Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Febuxostat Capsule may cause frequent urination, kidney stones, blood in urine, reduced ability to function properly, and abnormal urine tests. Talk to the doctor if you have any concerns.

You should know that Febuxostat Capsule may cause gout flares, cardiovascular events, and liver problems. Inform the doctor if you have kidney or liver problems, a history of heart disease or stroke, or if you are pregnant/breastfeeding.

Febuxostat Capsule may cause liver failure and liver function abnormalities. Consult the doctor if you notice signs of liver injury such as fatigue, right upper abdominal discomfort, jaundice, dark urine, or anorexia.

Country of origin

India
Other Info - FEB0050

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