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compositionComposition:NINTEDANIB-100MG
prescription
Prescription Medicine
info
Fibnib 100mg Soft Gelatin Capsule

Fibnib 100mg Soft Gelatin Capsule is used to treat idiopathic pulmonary fibrosis (a disease that causes scarring of the lungs). It contains Nintedanib, which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. In some cases, this medicine may cause side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NINTEDANIB-100MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Fibnib 100mg Soft Gelatin Capsule

Fibnib 100mg Soft Gelatin Capsule is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, which makes it difficult to breathe deeply.

Fibnib 100mg Soft Gelatin Capsule contains nintedanib, which helps reduce the scarring and swelling in the lungs by decreasing the release of naturally occurring growth factors in the body, allowing you to breathe better.

In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to Fibnib 100mg Soft Gelatin Capsule. Consult your doctor before taking Fibnib 100mg Soft Gelatin Capsule if you are pregnant or breastfeeding. Fibnib 100mg Soft Gelatin Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Consult your doctor if you are breastfeeding; your doctor will decide whether Fibnib 100mg Soft Gelatin Capsule can be taken by breastfeeding mothers or not.

Uses of Fibnib 100mg Soft Gelatin Capsule

Fibnib 100mg Soft Gelatin Capsule is used in the treatment of Idiopathic pulmonary fibrosis. The detailed uses of Fibnib 100mg Soft Gelatin Capsule are as follows: Treatment of Idiopathic pulmonary fibrosis

  • Idiopathic pulmonary fibrosis: Fibnib 100mg Soft Gelatin Capsule aids in the breakdown and thinning of mucus in the airways, facilitating coughing and removal. It is especially beneficial in conditions like Idiopathic pulmonary fibrosis.

Key Benefits

  • Fibnib 100mg Soft Gelatin Capsule is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults.
  • Fibnib 100mg Soft Gelatin Capsule can help effectively slow the rate of lung function decline by 50%.
  • Fibnib 100mg Soft Gelatin Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better.
  • Fibnib 100mg Soft Gelatin Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

  • Fibnib 100mg Soft Gelatin Capsule should be taken with meals to enhance its effectiveness.
  • It is recommended to take Fibnib 100mg Soft Gelatin Capsule twice daily or as advised by your doctor.
  • Swallow Fibnib 100mg Soft Gelatin Capsule as a whole with a glass of water.
  • Do not crush, chew, or open it.

How Fibnib 100mg Soft Gelatin Capsule Works

Fibnib 100mg Soft Gelatin Capsule contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Fibnib 100mg Soft Gelatin Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.
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Alcohol

Caution

It is not known if alcohol interacts with Fibnib 100mg Soft Gelatin Capsule. However, as a precautionary measure, you are recommended not to consume alcohol with the Fibnib 100mg Soft Gelatin Capsule to avoid unpleasant side effects.

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Pregnancy

Unsafe

Fibnib 100mg Soft Gelatin Capsule is listed as pregnancy category D. Because Fibnib 100mg Soft Gelatin Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Fibnib 100mg Soft Gelatin Capsule.

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Breast Feeding

Consult your doctor

Consult your doctor if you are breastfeeding; your doctor will decide whether Fibnib 100mg Soft Gelatin Capsule can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Fibnib 100mg Soft Gelatin Capsule may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

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Liver

Consult your doctor

Dose adjustment may be needed. Fibnib 100mg Soft Gelatin Capsule is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Consult your doctor

Dose adjustment may be needed. Fibnib 100mg Soft Gelatin Capsule is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

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Children

Unsafe

Fibnib 100mg Soft Gelatin Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

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Heart

Caution

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Fibnib 100mg Soft Gelatin Capsule should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Fibnib 100mg Soft Gelatin Capsule.

What if I have taken an overdose of Fibnib 100mg Soft Gelatin Capsule

Take Fibnib 100mg Soft Gelatin Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause serious adverse effects. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

Have a query?

How Soon It Starts Working

The time required for Fibnib 100mg Soft Gelatin Capsule to start to work: The exact onset time of Fibnib 100mg Soft Gelatin Capsule has not been clinically established. 

The time for which the effects of Fibnib 100mg Soft Gelatin Capsule last: The duration of Fibnib 100mg Soft Gelatin Capsule’s effect is clinically not established.

What if you forget to take Fibnib 100mg Soft Gelatin Capsule

If you forget to take a dose of Fibnib 100mg Soft Gelatin Capsule, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not double the dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Fibnib 100mg Soft Gelatin Capsule out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not use Fibnib 100mg Soft Gelatin Capsule if you are allergic to any components present in Fibnib 100mg Soft Gelatin Capsule.
  • Fibnib 100mg Soft Gelatin Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Fibnib 100mg Soft Gelatin Capsule.
  • Consult your doctor if you are breastfeeding; your doctor will decide whether the Fibnib 100mg Soft Gelatin Capsule can be taken by breastfeeding mothers or not.
  • Keep your doctor informed about your health condition and medicines to rule out any side effects. 
  • Fibnib 100mg Soft Gelatin Capsule may cause tiredness and dizziness, so drive with caution.
  • Avoid consuming alcohol with Fibnib 100mg Soft Gelatin Capsule as it could lead to increased dizziness.
  • Fibnib 100mg Soft Gelatin Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

verifiedApollotooltip

Drug-Drug Interactions: Fibnib 100mg Soft Gelatin Capsule may have interaction with medicines used to treat fungal infections (e.g. ketoconazole), medications used to treat bacterial infections/CYP3A4 inhibitors (e.g. erythromycin), drugs that affect your immune system (e.g. cyclosporine), antibiotic medicines used to treat tuberculosis (e.g. rifampicin), medicines to treat seizures (e.g. carbamazepine, phenytoin), and herbal medicines to treat depression (e.g. St. John’s Wort).

Drug-Food Interactions: Avoid grapefruit juice and chargrilled meats.

Drug-Disease Interactions: Fibnib 100mg Soft Gelatin Capsule may interact with smoking and severe hepatic and end-stage renal impairment requiring dialysis.

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Fibnib 100mg Soft Gelatin Capsule is used to treat idiopathic pulmonary fibrosis (IPF), a disease marked by a progressive decline in lung function.
Fibnib 100mg Soft Gelatin Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helping you breathe better.
Avoid smoking before starting the treatment while taking Fibnib 100mg Soft Gelatin Capsule as smoking might alter the effectiveness of Fibnib 100mg Soft Gelatin Capsule.
Fibnib 100mg Soft Gelatin Capsule should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Fibnib 100mg Soft Gelatin Capsule until your doctor asks you to stop it.
If you have any surgery, including dental surgery, please inform your doctor if you are taking Fibnib 100mg Soft Gelatin Capsule as your doctor might stop Fibnib 100mg Soft Gelatin Capsule before undergoing surgery.
In elderly patients, the risk of side effects is higher if you are taking Fibnib 100mg Soft Gelatin Capsule. For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.
It is not recommended to discontinue the Fibnib 100mg Soft Gelatin Capsule without consulting your healthcare provider. Abruptly stopping the medication can lead to disease progression or other complications. Consult your healthcare provider for personalised guidance if you have concerns or experience side effects.
If you forget to take a dose of Fibnib 100mg Soft Gelatin Capsule, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for the missed one, as this can increase the risk of side effects.
Common side effects of Fibnib 100mg Soft Gelatin Capsule may include nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity in some individuals. Most of these side effects do not require medical attention and will resolve gradually over time. However, if you experience these side effects persistently, inform your doctor.
Fibnib 100mg Soft Gelatin Capsule is not recommended for use in patients with severe liver impairment. Please consult your doctor if you have a liver impairment or any concerns before Fibnib 100mg Soft Gelatin Capsule.

Disclaimer

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Reference

  1. National Health Service (NHS). Treatment - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Pil.1786 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Nintedanib Nintedanib. 2014. [Accessed on 26 Mar. 2019] Check here
  5. Nintedanib esilate. 2015. [Accessed on 26 Mar. 2019] Check here
  6. NINTIB Capsules [Internet]. CiplaMed. 2025 [Accessed on 27 March 2025] Check here
  7. Conditions G. Idiopathic pulmonary fibrosis: MedlinePlus Genetics [Internet]. Medlineplus.gov. 2025 [Accessed on 27 March 2025]Check here

Country of origin

India
Other Info - FI98946
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