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  3. Fleta Infusion 75Mg/100Ml Inj

Fleta Infusion 75Mg/100Ml Inj, Pack of 1 Injection
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Fleta Infusion 75Mg/100Ml Inj is used to treat Myocardial Infarction and Acute Coronary Syndrome. It contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This inhibits fibrinogen binding, reducing the chance of blood clot formation. Fleta Infusion 75Mg/100Ml Inj reduces the risk of cardiovascular events like myocardial infarction (heart attack).

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Composition :

EPTIFIBATIDE-0.75MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fleta Infusion 75Mg/100Ml Inj

Fleta Infusion 75Mg/100Ml Inj belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Fleta Infusion 75Mg/100Ml Inj is used in the treatment of Acute coronary syndrome (ACS) in both patients who need to be managed medically and also people undergoing percutaneous coronary intervention (PCI) procedures. ACS is defined as a group of serious cardiac conditions wherein the blood flow to the heart decreases due to plaque formation. Fleta Infusion 75Mg/100Ml Inj is also used in the treatment of patients undergoing urgent PCI procedures and also in patients undergoing intracoronary stenting.

Fleta Infusion 75Mg/100Ml Inj contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Fleta Infusion 75Mg/100Ml Inj reduces the risk of cardiovascular events like myocardial infarction (heart attack).

Fleta Infusion 75Mg/100Ml Inj may cause certain side effects, such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, decreased platelet count, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer Fleta Infusion 75Mg/100Ml Inj. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Fleta Infusion 75Mg/100Ml Inj should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Fleta Infusion 75Mg/100Ml Inj is known to cause bleeding problems. If you observe severe bleeding that cannot be controlled, it is advised to stop administering Fleta Infusion 75Mg/100Ml Inj immediately. Hence, close monitoring is needed for any bleeding conditions. Talk to your doctor before receiving Fleta Infusion 75Mg/100Ml Inj if you had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking Fleta Infusion 75Mg/100Ml Inj. Fleta Infusion 75Mg/100Ml Inj is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of Fleta Infusion 75Mg/100Ml Inj

Fleta Infusion 75Mg/100Ml Inj is used to prevent heart attacks in high-risk patients. The detailed uses of Fleta Infusion 75Mg/100Ml Inj are as follows:<br/>• Prevents early myocardial infarction: Fleta Infusion 75Mg/100Ml Inj is used for unstable angina or non-Q-wave myocardial infarction, especially within 24 hours of chest pain.<br/>• Recommended for high-risk patients: Fleta Infusion 75Mg/100Ml Inj is beneficial for those with ECG changes, elevated cardiac enzymes, or those likely to undergo early PTCA.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Fleta Infusion 75Mg/100Ml Inj will be administered in the hospital setting by a trained healthcare professional.• Do not self-administer.

Medicinal Benefits

Fleta Infusion 75Mg/100Ml Inj contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Fleta Infusion 75Mg/100Ml Inj results in reducing the risk of cardiovascular events like myocardial infarction (heart attack) and other cardiac events.

How Fleta Infusion 75Mg/100Ml Inj Works

Fleta Infusion 75Mg/100Ml Inj contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Fleta Infusion 75Mg/100Ml Inj reduces the risk of cardiovascular events like myocardial infarction (heart attack).

Storage

• Store in a cool and dry place away from sunlight.
• Keep Fleta Infusion 75Mg/100Ml Inj out of the sight and reach of children.
• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Fleta Infusion 75Mg/100Ml Inj
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

What if I have taken an overdose of Fleta Infusion 75Mg/100Ml Inj

As Fleta Infusion 75Mg/100Ml Inj is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Do not receive Fleta Infusion 75Mg/100Ml Inj if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Fleta Infusion 75Mg/100Ml Inj is known to cause bleeding problems. However, if you observe severe bleeding that cannot be controlled, it is advised to stop administering Fleta Infusion 75Mg/100Ml Inj immediately. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Fleta Infusion 75Mg/100Ml Inj if you had a recent severe injury or surgery due to the risk of severe bleeding problems. Before taking Fleta Infusion 75Mg/100Ml Inj inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding due to serious foetal harm. Fleta Infusion 75Mg/100Ml Inj is not recommended for children below 12 years of age as efficacy and safety have not been established. Talk to your doctor before receiving Fleta Infusion 75Mg/100Ml Inj if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems.

Drug-Drug Interactions

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EptifibatideProtamine
Critical
EptifibatideDabigatran etexilate
Severe

Drug-Drug Interactions

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EptifibatideProtamine
Critical
How does the drug interact with Fleta Infusion 75Mg/100Ml Inj:
Coadministration of protamine and Fleta Infusion 75Mg/100Ml Inj may increase the risk of bleeding

How to manage the interaction:
Taking Fleta Infusion 75Mg/100Ml Inj with Protamine is not recommended, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
EptifibatideDabigatran etexilate
Severe
How does the drug interact with Fleta Infusion 75Mg/100Ml Inj:
Taking Dabigatran etexilate with Fleta Infusion 75Mg/100Ml Inj can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Fleta Infusion 75Mg/100Ml Inj together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
EptifibatideApixaban
Severe
How does the drug interact with Fleta Infusion 75Mg/100Ml Inj:
Coadministration of Fleta Infusion 75Mg/100Ml Inj and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Fleta Infusion 75Mg/100Ml Inj and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
EptifibatidePrasugrel
Severe
How does the drug interact with Fleta Infusion 75Mg/100Ml Inj:
Co-administration of Fleta Infusion 75Mg/100Ml Inj with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel with Fleta Infusion 75Mg/100Ml Inj can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
EptifibatideIbrutinib
Severe
How does the drug interact with Fleta Infusion 75Mg/100Ml Inj:
Co-administration of Ibrutinib with Fleta Infusion 75Mg/100Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Ibrutinib with Fleta Infusion 75Mg/100Ml Inj together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Fleta Infusion 75Mg/100Ml Inj Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption. Consult your doctor for more information.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Fleta Infusion 75Mg/100Ml Inj. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Fleta Infusion 75Mg/100Ml Inj. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Not applicable

Fleta Infusion 75Mg/100Ml Inj is used in PCI procedures in a hospital setting. Driving is not recommended.

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Liver

Caution

If you have liver problems, inform your doctor beforehand.

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Kidney

Caution

If you have kidney impairment, inform your doctor beforehand. Fleta Infusion 75Mg/100Ml Inj is not recommended for use in patients with renal toxicity.

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Children

Unsafe

Fleta Infusion 75Mg/100Ml Inj is not recommended for use in children below 12 years of age, as efficacy and safety have not been established.

Have a query?

FAQs

Fleta Infusion 75Mg/100Ml Inj is used to treat Myocardial Infraction and Acute Coronary Syndrome.

Fleta Infusion 75Mg/100Ml Inj contains Eptifibatide (anti-glycoprotein IIb/IIIa receptor), which works by blocking the glycoprotein IIb/IIIa receptor&#039;s activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.

Fleta Infusion 75Mg/100Ml Inj is known to increase the risk of bleeding. However, if the patient has uncontrollable bleeding, discontinue the medicine immediately.

Fleta Infusion 75Mg/100Ml Inj may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.

Country of origin

India

Manufacturer/Marketer address

3M India Ltd, Concorde Block, UB City, #24, Vittal Mallya Road, Bangalore, Karnataka - 560001 India
Other Info - FLE0036

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.ncbi.nlm.nih.gov/books/NBK541066/
  2. https://go.drugbank.com/drugs/DB00063
  3. https://reference.medscape.com/drug/integrilin-eptifibatide-342149#4
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020718s037lbl.pdf
  5. https://www.rxlist.com/integrilin-drug.htm

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