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  3. Fluconazole 200 mg/100 ml I.V.

Fluconazole 200 mg/100 ml I.V., Pack of 1 INFUSION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Fluconazole 200 mg/100 ml I.V. is an antifungal medication used i the treatment of fungal and yeast infections. This medicine works by stopping the enzyme that is responsible for fungal growth and leading to the death of the microbes. Common side effects include headache, diarrhoea, nausea, stomach upset, dizziness, and stomach pain.
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Composition :

FLUCONAZOLE-200MG

Manufacturer/Marketer :

3M India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fluconazole 200 mg/100 ml I.V.

Fluconazole 200 mg/100 ml I.V. belongs to the class of medicines called 'antifungals' used to treat a broad range of infections caused by fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood.

Fluconazole 200 mg/100 ml I.V. contains ‘Fluconazole’ that kills or prevents fungi or yeast growth by inhibiting an enzyme responsible for its normal fat metabolism. This interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed or their growth is minimized.

Fluconazole 200 mg/100 ml I.V. may cause common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to any of the components in Fluconazole 200 mg/100 ml I.V.. Let your doctor know if you have any liver, kidney or heart problems before starting Fluconazole 200 mg/100 ml I.V.. Pregnant and breastfeeding women should consult their doctor before starting Fluconazole 200 mg/100 ml I.V.. It is advised to avoid alcohol intake while using Fluconazole 200 mg/100 ml I.V. to prevent any undesirable effects.

Uses of Fluconazole 200 mg/100 ml I.V.

Treatment of Fungal infections

Directions for Use

Fluconazole 200 mg/100 ml I.V. will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Fluconazole 200 mg/100 ml I.V. is used to treat various fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), oesophagal candidiasis (candida esophagitis), candida infections (urinary tract infections, peritonitis), and cryptococcal meningitis. Besides this, Fluconazole 200 mg/100 ml I.V. is also used to prevent candidiasis and coccidioidomycosis in patients who receive cancer or radiation treatment while undergoing bone marrow transplantation. Fluconazole 200 mg/100 ml I.V. is effective in treating soft tissue and pulmonary infections when compared to other azole antifungal drugs. It works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation.

How Fluconazole 200 mg/100 ml I.V. Works

Fluconazole 200 mg/100 ml I.V. contains ‘Fluconazole’ that kills or prevents fungi or yeast growth by inhibiting an enzyme responsible for its normal fat metabolism. This interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed or their growth is minimized.

Storage

Store in a cool and dry place away from sunlight
Side effects of Fluconazole 200 mg/100 ml I.V.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Fluconazole 200 mg/100 ml I.V.

Fluconazole 200 mg/100 ml I.V. is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. Overdose symptoms include seeing, hearing, or sensing things that are not there; feeling fearful, suspicious, or experiencing other mental changes. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Please inform your doctor if you use any prescription, or non-prescription medicines, including vitamin and herbal supplements before using Fluconazole 200 mg/100 ml I.V.. Do not use Fluconazole 200 mg/100 ml I.V. if you are allergic to any of its components. Let your doctor know if you have any liver, kidney, or heart problems, a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. Pregnant or lactating women should consult the doctor before taking Fluconazole 200 mg/100 ml I.V.. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Fluconazole 200 mg/100 ml I.V. to avoid undesirable effects.

Drug-Drug Interactions

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FluconazoleErythromycin
Critical
FluconazoleLomitapide
Critical

Drug-Drug Interactions

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FluconazoleErythromycin
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking Fluconazole 200 mg/100 ml I.V. with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Lomitapide is taken with Fluconazole 200 mg/100 ml I.V., may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleEliglustat
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Eliglustat and Fluconazole 200 mg/100 ml I.V. are taken together, Fluconazole 200 mg/100 ml I.V. can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Astemizole is taken with Fluconazole 200 mg/100 ml I.V., the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleDicoumarol
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking Fluconazole 200 mg/100 ml I.V. with Dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction, Fluconazole 200 mg/100 ml I.V. can be taken with Dicumarol if prescribed by the doctor. Consult the doctor if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue the medications without a doctor's advice.
FluconazoleGlibenclamide
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of Glibenclamide with Fluconazole 200 mg/100 ml I.V. may cause an increase in the blood levels and effects of Glibenclamide leading to low blood sugar levels.

How to manage the interaction:
Although there is a possible interaction, Glibenclamide can be taken with Fluconazole 200 mg/100 ml I.V. if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
FluconazoleSimvastatin
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of Simvastatin together with Fluconazole 200 mg/100 ml I.V. can increase the blood levels of Simvastatin and can increase the risk of liver damage.

How to manage the interaction:
Co-administration of Simvastatin and Fluconazole 200 mg/100 ml I.V. can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, fever, dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FluconazoleDolasetron
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of Dolasetron taken with Fluconazole 200 mg/100 ml I.V. can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Fluconazole 200 mg/100 ml I.V. and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms - like an irregular heart rhythm, a heart condition, or prolonged diarrhea - it's best to call a doctor right away. Other symptoms to watch out for include sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
FluconazoleRuxolitinib
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of Ruxolitinib with Fluconazole 200 mg/100 ml I.V. may increase the blood levels of Ruxolitinib.

How to manage the interaction:
Although there is a possible interaction, Fluconazole 200 mg/100 ml I.V. can be taken with Ruxolitinib if prescribed by the doctor. Consult the doctor if you experience signs and symptoms such as paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms. Do not discontinue the medications without consulting a doctor.
FluconazoleClopidogrel
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of clopidogrel with Fluconazole 200 mg/100 ml I.V. can reduce the effectiveness of clopidogrel.

How to manage the interaction:
Clopidogrel and Fluconazole 200 mg/100 ml I.V. may interact, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Avoid or limit the intake of alcohol and caffeine.
  • Take non-starchy vegetables and gluten-free foods.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Fluconazole 200 mg/100 ml I.V. Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is advisable to avoid or limit the intake of alcohol while on treatment with Fluconazole 200 mg/100 ml I.V..

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Pregnancy

Caution

Please consult your doctor if you are pregnant or are planning to conceive before starting Fluconazole 200 mg/100 ml I.V..

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Breast Feeding

Caution

Fluconazole 200 mg/100 ml I.V. should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.

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Driving

Caution

Fluconazole 200 mg/100 ml I.V. may sometimes cause dizziness or other side effects that may affect your mental ability to drive. Hence do not drive or operate machinery if you are not mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases when you are prescribed Fluconazole 200 mg/100 ml I.V..

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases when you are prescribed Fluconazole 200 mg/100 ml I.V..

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Children

Caution

Fluconazole 200 mg/100 ml I.V. should be given to children only when prescribed by a doctor. The doctor decides the right dose for a child based on his/her age and weight.

Have a query?

FAQs

Fluconazole 200 mg/100 ml I.V. belongs to the class of medicines called 'antifungals' used to treat a broad range of infections caused by fungi and yeast.

Fluconazole 200 mg/100 ml I.V. works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections.

Co-administration of terfenadine (anti-histamine), cisapride (antacid) with Fluconazole 200 mg/100 ml I.V. is not recommended. However, consult your doctor before taking Fluconazole 200 mg/100 ml I.V. with other medicines.

Fluconazole 200 mg/100 ml I.V. may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. However, seek a doctor's advice before using Fluconazole 200 mg/100 ml I.V. if you have a previous medical history.

Diarrhoea could be a side effect of Fluconazole 200 mg/100 ml I.V.. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if your condition does not improve or if it worsens.

Country of origin

India

Manufacturer/Marketer address

3M India Ltd, Concorde Block, Ub City, #24, Vittal Mallya Road, Bangalore, Karnataka - 560001 India.
Other Info - FLU0012

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jan 1, 2025 | 2:45 PM IST

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Reference

  1. https://www.drugs.com/mtm/fluconazole.html
  2. https://www.nhs.uk/medicines/fluconazole
  3. https://cdn.pfizer.com/pfizercom/products/uspi_fluconazole.pdf
  4. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d3ca59bd-ae00-48ab-89aa-87c7f56e9989&type=display
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