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Composition :

LETROZOLE-2.5MG

Manufacturer/Marketer :

Uniza Healthcare Llp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Folletro 2.5 Tablet

Folletro 2.5 Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.

Folletro 2.5 Tablet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. 

In some cases, Folletro 2.5 Tablet may cause common side effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.

You are advised to take Folletro 2.5 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. It can be taken with or without food with a glass of water. Do not chew, bite or crush the medicine.

Avoid taking Folletro 2.5 Tablet if you are allergic to it, or if you are pregnant or breastfeeding. Folletro 2.5 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Folletro 2.5 Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Folletro 2.5 Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Folletro 2.5 Tablet

Folletro 2.5 Tablet is used in the treatment of Breast cancer. The detailed uses of Folletro 2.5 Tablet are as follows:

  • Breast Cancer Treatment: Folletro 2.5 Tablet is primarily prescribed for postmenopausal women with hormone-receptor-positive breast cancer. It works by lowering estrogen levels, which helps slow or halt the growth of certain breast tumours.
  • Adjuvant Therapy: After surgery for early-stage breast cancer, Folletro 2.5 Tablet may be used as adjuvant therapy to reduce the risk of recurrence and improve survival rates.
  • Neoadjuvant Therapy: Folletro 2.5 Tablet can serve as a neoadjuvant treatment to shrink breast tumours before surgery, facilitating their removal.
  • Ovarian Function Suppression: Folletro 2.5 Tablet is occasionally used off-label during fertility treatments to suppress ovarian function, particularly in cases of polycystic ovary syndrome (PCOS).

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Directions for Use

  • Take Folletro 2.5 Tablet with or without food as advised by your doctor.
  • It is advised to take Folletro 2.5 Tablet once daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Folletro 2.5 Tablet as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

  • Folletro 2.5 Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors.
  • Folletro 2.5 Tablet is used to treat breast cancer in women who have gone through menopause (cessation of periods).
  • Folletro 2.5 Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

How Folletro 2.5 Tablet Works

Folletro 2.5 Tablet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Folletro 2.5 Tablet prevents the growth of cancer cells. Thereby Folletro 2.5 Tablet helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Folletro 2.5 Tablet

Do not take more than the prescribed dose of Folletro 2.5 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Folletro 2.5 Tablet if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods).
  • Talk to your doctor before taking Folletro 2.5 Tablet if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease.
  • Folletro 2.5 Tablet may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Folletro 2.5 Tablet.
  • Avoid taking Folletro 2.5 Tablet if you are pregnant or breastfeeding.
  • Folletro 2.5 Tablet may cause drowsiness and dizziness, so drive only if you are alert.
  • Folletro 2.5 Tablet is not recommended for use in children as safety has not been established.
  • Avoid consuming alcohol along with Folletro 2.5 Tablet as it could lead to increased drowsiness and dizziness. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Folletro 2.5 Tablet:
Folletro 2.5 Tablet may have a negative effect when used with Estradiol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Folletro 2.5 Tablet and estradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Folletro 2.5 Tablet:
Co-administration of Folletro 2.5 Tablet and Citalopram may raise the risk of a serious irregular heartbeat.

How to manage the interaction:
Although taking Folletro 2.5 Tablet and Citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleDiethylstilbestrol
Severe
How does the drug interact with Folletro 2.5 Tablet:
Co-administration of Folletro 2.5 Tablet may have an effect when used with Diethylstilbestrol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Folletro 2.5 Tablet and diethylstilbestrol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleEstrone
Severe
How does the drug interact with Folletro 2.5 Tablet:
When taken together Folletro 2.5 Tablet's function could be blocked by estrone, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Folletro 2.5 Tablet and estrone together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Folletro 2.5 Tablet:
Coadministration of thalidomide and Folletro 2.5 Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking Folletro 2.5 Tablet and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Folletro 2.5 Tablet:
when taken together Folletro 2.5 Tablet's function could be blocked by estramustine, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Folletro 2.5 Tablet and estramustine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Folletro 2.5 Tablet:
When taken together ethinyl estradiol may interfere with Folletro 2.5 Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Folletro 2.5 Tablet and ethinylestradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
LetrozoleConjugated Estrogens
Severe
How does the drug interact with Folletro 2.5 Tablet:
Coadministration of Conjugated estrogens with Folletro 2.5 Tablet may reduce the effect of Folletro 2.5 Tablet.

How to manage the interaction:
Although taking Conjugated estrogen and Folletro 2.5 Tablet together can result in an interaction, it can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Folletro 2.5 Tablet:
Co-administration of Desogestrel together with Folletro 2.5 Tablet may decrease the effects of Folletro 2.5 Tablet.

How to manage the interaction:
Although taking Folletro 2.5 Tablet and Desogestrel together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.

  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.

  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Folletro 2.5 Tablet to avoid unpleasant side effects. Alcohol intake, along with Folletro 2.5 Tablet, may cause increased drowsiness.

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Pregnancy

Unsafe

Folletro 2.5 Tablet is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

Folletro 2.5 Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Unsafe

Folletro 2.5 Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take Folletro 2.5 Tablet if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take Folletro 2.5 Tablet if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Folletro 2.5 Tablet should not be used by children, as the efficacy and safety have not been established.

FAQs

Folletro 2.5 Tablet belongs to the group of anti-cancer medicines used to treat breast cancer in women.

Folletro 2.5 Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Folletro 2.5 Tablet prevents the growth of cancer cells. Thereby, Folletro 2.5 Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Folletro 2.5 Tablet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

High blood pressure could be a side-effect of Folletro 2.5 Tablet. Regularly monitor blood pressure levels while taking Folletro 2.5 Tablet. Consult your doctor if you regularly notice high blood pressure levels.

Do not stop taking Folletro 2.5 Tablet on your own. You are advised to take Folletro 2.5 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Folletro 2.5 Tablet.

Folletro 2.5 Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Folletro 2.5 Tablet.

Folletro 2.5 Tablet may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.

Folletro 2.5 Tablet should be swallowed as a whole with water; do not crush or chew it.

Folletro 2.5 Tablet can be taken with or without food.

Folletro 2.5 Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Folletro 2.5 Tablet is prescribed to treat breast cancer in women who have gone through menopause.

Folletro 2.5 Tablet may cause high blood pressure. Therefore, irbesartan should be taken with Folletro 2.5 Tablet only if prescribed by the doctor. Regularly monitor blood pressure levels while taking Folletro 2.5 Tablet.

Folletro 2.5 Tablet may cause eye problems like blurred vision and cataracts. Consult the doctor if you experience blurred vision or eye irritation.

Folletro 2.5 Tablet may cause hot flushes leading to sweating. These symptoms usually improve during the first few months. However, if the symptoms persist or worsen, consult the doctor.

Serious side effects of Folletro 2.5 Tablet are difficulty breathing, chest pain, fainting, rapid heart rate, formation of blood clots (bluish skin discolouration, or sudden arm, leg or foot pain) and rupture of a tendon. These side effects are rare and may not occur in everyone taking Folletro 2.5 Tablet.

Letrozole may induce ovulation in anovulatory infertility patients and augment follicles for ovulatory women. However, it is an off-label use. Talk to the doctor if you have any concerns.

Folletro 2.5 Tablet is not recommended for use during pregnancy or while breastfeeding.

The time required for Folletro 2.5 Tablet to show its effects depends upon your condition and severity. Consult the doctor if you have any concerns.

If you miss a dose of Folletro 2.5 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Folletro 2.5 Tablet may interact with antidepressants (citalopram, escitalopram) and anticancer medicines (tamoxifen). Let the doctor know if you are taking these medicines.

Store Folletro 2.5 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

C-401, Ganesh Meridian, Opp. Gujarat High Court, Sarkhej - Gandhinagar Hwy, Sola, Ahmedabad, Gujarat 380060
Other Info - FOL0839

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