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  1. Home
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  3. Folletro Tablet 5's

Prescription drug
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Folletro Tablet 5's, Pack of 5
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Folletro Tablet 5's is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). It contains Letrozole, which prevents the growth of cancer cells. Thereby, it helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts. It may cause certain common side effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

LETROZOLE-5MG

Manufacturer/Marketer :

Uniza Healthcare Llp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Folletro Tablet 5's

Folletro Tablet 5's is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.

Folletro Tablet 5's contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. 

In some cases, Folletro Tablet 5's may cause common side effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.

You are advised to take Folletro Tablet 5's for as long as your doctor has prescribed it for you, depending on your medical condition. It can be taken with or without food with a glass of water. Do not chew, bite or crush the medicine.

Avoid taking Folletro Tablet 5's if you are allergic to it, or if you are pregnant or breastfeeding. Folletro Tablet 5's may cause drowsiness and dizziness, so drive only if you are alert. Folletro Tablet 5's should not be given to children as safety has not been established. Avoid consuming alcohol along with Folletro Tablet 5's as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Folletro Tablet 5's

Folletro Tablet 5's is used in the treatment of Breast cancer. The detailed uses of Folletro Tablet 5's are as follows:

  • Breast Cancer Treatment: Folletro Tablet 5's is primarily prescribed for postmenopausal women with hormone-receptor-positive breast cancer. It works by lowering estrogen levels, which helps slow or halt the growth of certain breast tumours.
  • Adjuvant Therapy: After surgery for early-stage breast cancer, Folletro Tablet 5's may be used as adjuvant therapy to reduce the risk of recurrence and improve survival rates.
  • Neoadjuvant Therapy: Folletro Tablet 5's can serve as a neoadjuvant treatment to shrink breast tumours before surgery, facilitating their removal.
  • Ovarian Function Suppression: Folletro Tablet 5's is occasionally used off-label during fertility treatments to suppress ovarian function, particularly in cases of polycystic ovary syndrome (PCOS).

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Directions for Use

  • Take Folletro Tablet 5's with or without food as advised by your doctor.
  • It is advised to take Folletro Tablet 5's once daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Folletro Tablet 5's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Folletro Tablet 5's belongs to the group of anti-cancer medicines called aromatase inhibitors.
  • Folletro Tablet 5's is used to treat breast cancer in women who have gone through menopause (cessation of periods).
  • Folletro Tablet 5's helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

How Folletro Tablet 5's Works

Folletro Tablet 5's contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Folletro Tablet 5's prevents the growth of cancer cells. Thereby Folletro Tablet 5's helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Folletro Tablet 5's

Do not take more than the prescribed dose of Folletro Tablet 5's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Folletro Tablet 5's if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods).
  • Talk to your doctor before taking Folletro Tablet 5's if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease.
  • Folletro Tablet 5's may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Folletro Tablet 5's.
  • Avoid taking Folletro Tablet 5's if you are pregnant or breastfeeding.
  • Folletro Tablet 5's may cause drowsiness and dizziness, so drive only if you are alert.
  • Folletro Tablet 5's is not recommended for use in children as safety has not been established.
  • Avoid consuming alcohol along with Folletro Tablet 5's as it could lead to increased drowsiness and dizziness. 

Drug-Drug Interactions

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LetrozoleCitalopram
Severe
LetrozoleThalidomide
Severe

Drug-Drug Interactions

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LetrozoleCitalopram
Severe
How does the drug interact with Folletro Tablet:
Co-administration of Folletro Tablet and Citalopram may raise the risk of a serious irregular heartbeat.

How to manage the interaction:
Although taking Folletro Tablet and Citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleThalidomide
Severe
How does the drug interact with Folletro Tablet:
Coadministration of thalidomide and Folletro Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking Folletro Tablet and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleDiethylstilbestrol
Severe
How does the drug interact with Folletro Tablet:
Co-administration of Folletro Tablet may have an effect when used with Diethylstilbestrol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Folletro Tablet and diethylstilbestrol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleEstrone
Severe
How does the drug interact with Folletro Tablet:
When taken together Folletro Tablet's function could be blocked by estrone, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Folletro Tablet and estrone together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleEstramustine
Severe
How does the drug interact with Folletro Tablet:
when taken together Folletro Tablet's function could be blocked by estramustine, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Folletro Tablet and estramustine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleEthinylestradiol
Severe
How does the drug interact with Folletro Tablet:
When taken together ethinyl estradiol may interfere with Folletro Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Folletro Tablet and ethinylestradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
LetrozoleConjugated Estrogens
Severe
How does the drug interact with Folletro Tablet:
Coadministration of Conjugated estrogens with Folletro Tablet may reduce the effect of Folletro Tablet.

How to manage the interaction:
Although taking Conjugated estrogen and Folletro Tablet together can result in an interaction, it can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
LetrozoleDesogestrel
Severe
How does the drug interact with Folletro Tablet:
Co-administration of Desogestrel together with Folletro Tablet may decrease the effects of Folletro Tablet.

How to manage the interaction:
Although taking Folletro Tablet and Desogestrel together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any medications.
LetrozoleEstradiol
Severe
How does the drug interact with Folletro Tablet:
Folletro Tablet may have a negative effect when used with Estradiol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Folletro Tablet and estradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.

  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.

  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Folletro Tablet 5's to avoid unpleasant side effects. Alcohol intake, along with Folletro Tablet 5's, may cause increased drowsiness.

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Pregnancy

Unsafe

Folletro Tablet 5's is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

Folletro Tablet 5's should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Unsafe

Folletro Tablet 5's may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take Folletro Tablet 5's if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take Folletro Tablet 5's if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Folletro Tablet 5's should not be used by children, as the efficacy and safety have not been established.

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Heart

Folletro Tablet 5's is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Caution

Caution should be exercised while taking Folletro Tablet 5's in geriatric patients, as it can lead to adverse effects.

FAQs

Folletro Tablet 5's belongs to the group of anti-cancer medicines used to treat breast cancer in women.

Folletro Tablet 5's works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Folletro Tablet 5's prevents the growth of cancer cells. Thereby, Folletro Tablet 5's helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Folletro Tablet 5's causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

High blood pressure could be a side-effect of Folletro Tablet 5's. Regularly monitor blood pressure levels while taking Folletro Tablet 5's. Consult your doctor if you regularly notice high blood pressure levels.

Do not stop taking Folletro Tablet 5's on your own. You are advised to take Folletro Tablet 5's for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Folletro Tablet 5's.

Folletro Tablet 5's may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Folletro Tablet 5's.

Folletro Tablet 5's may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.

Folletro Tablet 5's should be swallowed as a whole with water; do not crush or chew it.

Folletro Tablet 5's can be taken with or without food.

Folletro Tablet 5's should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Folletro Tablet 5's is prescribed to treat breast cancer in women who have gone through menopause.

Folletro Tablet 5's may cause high blood pressure. Therefore, irbesartan should be taken with Folletro Tablet 5's only if prescribed by the doctor. Regularly monitor blood pressure levels while taking Folletro Tablet 5's.

Folletro Tablet 5's may cause eye problems like blurred vision and cataracts. Consult the doctor if you experience blurred vision or eye irritation.

Folletro Tablet 5's may cause hot flushes leading to sweating. These symptoms usually improve during the first few months. However, if the symptoms persist or worsen, consult the doctor.

Serious side effects of Folletro Tablet 5's are difficulty breathing, chest pain, fainting, rapid heart rate, formation of blood clots (bluish skin discolouration, or sudden arm, leg or foot pain) and rupture of a tendon. These side effects are rare and may not occur in everyone taking Folletro Tablet 5's.

Letrozole may induce ovulation in anovulatory infertility patients and augment follicles for ovulatory women. However, it is an off-label use. Talk to the doctor if you have any concerns.

Folletro Tablet 5's is not recommended for use during pregnancy or while breastfeeding.

The time required for Folletro Tablet 5's to show its effects depends upon your condition and severity. Consult the doctor if you have any concerns.

If you miss a dose of Folletro Tablet 5's take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Folletro Tablet 5's may interact with antidepressants (citalopram, escitalopram) and anticancer medicines (tamoxifen). Let the doctor know if you are taking these medicines.

Store Folletro Tablet 5's at room temperature, in a dry place. Keep out of sight and reach of children.

Country of origin

INDIA

Manufacturer/Marketer address

C-401, Ganesh Meridian, Opp. Gujarat High Court, Sarkhej - Gandhinagar Hwy, Sola, Ahmedabad, Gujarat 380060
Other Info - FOL1050

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:33 AM IST

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Reference

  1. https://mri.cts-mrp.eu/human/downloads/NL_H_1179_001_FinalPI.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/020726s014lbl.pdf
  3. https://www.novartis.com.sg/system/files/product-info/Femera%20PI%20Dec%202016.SIN_.pdf
  4. https://www.drugs.com/mtm/letrozole.html
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