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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Framic M Tablet 500mg/250mg is used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, it is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. It contains two medicines, namely Tranexamic acid and Mefenamic acid. It may cause common side effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache.

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Manufacturer/Marketer :

Surge Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Framic M Tablet 500mg/250mg

Framic M Tablet 500mg/250mg is a combination medicine used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, Framic M Tablet 500mg/250mg is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Menstrual cramps, also known as dysmenorrhea, are characterized by cramps and pain during menstruation. Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods.

Framic M Tablet 500mg/250mg is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

You are advised to take Framic M Tablet 500mg/250mg for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Framic M Tablet 500mg/250mg may cause dizziness, so drive with caution. Framic M Tablet 500mg/250mg should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Framic M Tablet 500mg/250mg as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Framic M Tablet 500mg/250mg

Framic M Tablet 500mg/250mg is used in the treatment of dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). The detailed uses of Framic M Tablet 500mg/250mg are as follows:

  • Management of Menstrual Disorders: Framic M Tablet 500mg/250mg is used to help regulate menstrual cycles in women experiencing irregular periods or hormonal imbalances.
  • Relief from Menopausal Symptoms: Framic M Tablet 500mg/250mg can alleviate symptoms associated with menopause, such as hot flashes and mood swings.
  • PMS Symptom Relief: Framic M Tablet 500mg/250mg is effective in minimising premenstrual syndrome (PMS) symptoms, including cramps, anxiety, and other mood-related issues associated with the menstrual cycle.

Directions for Use

• Framic M Tablet 500mg/250mg can be taken with or without food. • Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness. • Swallow Framic M Tablet 500mg/250mg as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

Framic M Tablet 500mg/250mg is a combination of two drugs, namely: Tranexamic acid and Mefenamic acid. Framic M Tablet 500mg/250mg is used to treat abdominal pain, dysmenorrhea (period pain), and menorrhagia (heavy menstrual bleeding). Additionally, Framic M Tablet 500mg/250mg is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Tranexamic acid is an anti-fibrinolytic agent that helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid is an NSAID that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Framic M Tablet 500mg/250mg helps treat heavy bleeding and pains/cramps during periods.

How Framic M Tablet 500mg/250mg Works

Framic M Tablet 500mg/250mg is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Framic M Tablet 500mg/250mg

Do not take more than the prescribed dose of Framic M Tablet 500mg/250mg as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Framic M Tablet 500mg/250mg if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Framic M Tablet 500mg/250mg may cause dizziness and drowsiness, so drive only if you are alert. Framic M Tablet 500mg/250mg should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Framic M Tablet 500mg/250mg as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Do not take any other NSAIDs for pain relief along with Framic M Tablet 500mg/250mg unless prescribed.

Drug-Drug Interactions

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Tranexamic acidEtonogestrel
Critical

Drug-Drug Interactions

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How does the drug interact with Framic M Tablet 500mg/250mg:
Taking Medroxyprogesterone acetate with Framic M Tablet 500mg/250mg may increase the risk of blood clots.

How to manage the interaction:
Taking Medroxyprogesterone with Framic M Tablet 500mg/250mg is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
Tranexamic acidEtonogestrel
Critical
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of Framic M Tablet 500mg/250mg may cause blood clotting when taken with Etonogestrel.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Etonogestrel is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
How does the drug interact with Framic M Tablet 500mg/250mg:
Taking Ethinylestradiol with Framic M Tablet 500mg/250mg may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ethinylestradiol with Framic M Tablet 500mg/250mg is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Taking Levonorgestrel with Framic M Tablet 500mg/250mg may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Levonorgestrel may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Taking drospirenone with Framic M Tablet 500mg/250mg may increase the risk of blood clot formation.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Drospirenone is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
How does the drug interact with Framic M Tablet 500mg/250mg:
Coadministration of Framic M Tablet 500mg/250mg with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of Framic M Tablet 500mg/250mg with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of tretinoin with Framic M Tablet 500mg/250mg may increase the risk of blood clots.

How to manage the interaction:
Taking tretinoin with Framic M Tablet 500mg/250mg is not recommended due to its increased effects, however, it can be taken only if your doctor has advised it. If you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidConjugated Estrogens
Severe
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of Conjugated estrogen with Framic M Tablet 500mg/250mg can increase the risk of blood clots.

How to manage the interaction:
Taking Conjugated estrogen with Framic M Tablet 500mg/250mg may result in interaction, it can be taken only if your doctor has advised it. However, if you experience chest pain, shortness of breath, coughing up blood, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of Carfilzomib with Framic M Tablet 500mg/250mg can increase the risk of blood clots.

How to manage the interaction:
Taking carfilzomib with Framic M Tablet 500mg/250mg is not recommended due to its increased effects, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.

  • Stay hydrated; drink plenty of water.

  • Cut down on sugars, salts, spicy food, coffee, and alcohol.

  • A heating pad can help ease the pain by placing it on the belly or lower back.

  • Exercise can help ease the pain of menstrual cramps.

  • Avoid stress by performing meditation or yoga.

  • Massage your lower back or abdomen to relieve the pain.

  • Take proper rest.

Habit Forming

No

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Framic M Tablet 500mg/250mg as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Framic M Tablet 500mg/250mg if you are breastfeeding, your doctor will decide if Framic M Tablet 500mg/250mg can be taken by breastfeeding mothers or not.

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Driving

Caution

Framic M Tablet 500mg/250mg may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Framic M Tablet 500mg/250mg should not be given to children as the safety and effectiveness were not established.

Have a query?

FAQs

Framic M Tablet 500mg/250mg is used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, it is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache.

Framic M Tablet 500mg/250mg contains Tranexamic acid and Mefenamic acid. Tranexamic acid helps the body's natural blood clot process by preventing the breakdown of fibrin, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

Diarrhoea might be a side-effect of Framic M Tablet 500mg/250mg. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.

Framic M Tablet 500mg/250mg should not be taken for longer durations unless prescribed by the doctor. Framic M Tablet 500mg/250mg is usually prescribed for a few days at the time of heavy bleeding and cramps.

Framic M Tablet 500mg/250mg is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Framic M Tablet 500mg/250mg only as prescribed and do not overdose.

Consult your doctor before taking contraceptive pills along with Framic M Tablet 500mg/250mg. When taken together, there is an increased risk of deep vein thrombosis (blood clot in the deep vein, usually legs).

Framic M Tablet 500mg/250mg contains mefenamic acid, an NSAID which might increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. Therefore, avoid taking Framic M Tablet 500mg/250mg if you have heart-related problems unless prescribed by the doctor.

Framic M Tablet 500mg/250mg typically starts to show its effects within 1-2 hours of taking it, and it helps to reduce heavy menstrual bleeding by improving blood clotting but does not stop bleeding. However, the exact duration for bleeding to stop can vary from one person to other.

Yes, Framic M Tablet 500mg/250mg can cause acidity. If you experience heartburn and indigestion, it's advisable to take Framic M Tablet 500mg/250mg with food to minimize discomfort. If the symptoms persist, please consult your doctor.

Yes, Framic M Tablet 500mg/250mg is safe if you take as per the dose and duration prescribed by your doctor. However, it's important to be aware of potential side effects and contraindications. Always consult your doctor before starting any new medication to ensure it is safe for you, especially if you have pre-existing conditions or are taking other medications.

Always follow your doctor's instructions regarding dosage and duration. Usually it is prescribed for a short duration. Do not exceed the prescribed duration. As overuse can lead to side effects and other health issues.

Framic M Tablet 500mg/250mg is a combination of two drugs, tranexamic acid (anti-fibrinolytic) and mefenamic acid (NSAID).

Yes, do not take Framic M Tablet 500mg/250mg if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Do not take any other NSAIDs for pain relief along with Framic M Tablet 500mg/250mg unless prescribed.

Store Framic M Tablet 500mg/250mg at a temperature not exceeding 25°C. Protect it from light and moisture. Keep out of reach of children.

Yes, you can take Framic M Tablet 500mg/250mg with food. It is often recommended to take it after a meal to avoid stomach upset or other gastrointestinal side effects.

Please consult your doctor if you are pregnant. Your doctor will prescribes Framic M Tablet 500mg/250mg only if the benefits outweigh the risks.

The common side effects of Framic M Tablet 500mg/250mg are nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. If any of these side effects persist or worsen, please consult your doctor.

You are recommended to consult your doctor before taking other medicines with Framic M Tablet 500mg/250mg to avoid possible interactions.

Country of origin

India
Other Info - FR12234

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