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  3. Fulvetraz 250 mg Injection 5 ml

Fulvetraz 250 mg Injection 5 ml, Pack of 1 INJECTION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Fulvetraz 250 mg Injection 5 ml is used to treat breast cancer in postmenopausal women. It contains Fulvestrant, which works by inhibiting some of the actions of estrogen (female sex hormone which may help cancer cells grow in women with breast cancer) and reducing the amount that is in the body. Thus, it helps in reducing breast cancer tumour growth. In some cases, Fulvetraz 250 mg Injection 5 ml may cause certain common side effects such as injection site reactions like pain and/or inflammation, weakness, nausea, tiredness, headache or joint and musculoskeletal pain.

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Composition :

FULVESTRANT-250MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fulvetraz 250 mg Injection 5 ml

Fulvetraz 250 mg Injection 5 ml belongs to the class of estrogen blockers used to treat breast cancer in postmenopausal women. Breast cancer is a type of cancer that develops when the breast cells begin to grow abnormally.

Fulvetraz 250 mg Injection 5 ml contains Fulvestrant, which works by inhibiting some of the actions of estrogen (female sex hormone which may help cancer cells grow in women with breast cancer) and reducing the amount that is in the body. Thus, it helps in reducing breast cancer tumour growth.

Fulvetraz 250 mg Injection 5 ml will be administered by a healthcare professional; do not self-administer. In some cases, Fulvetraz 250 mg Injection 5 ml may cause certain common side effects such as injection site reactions like pain and/or inflammation, weakness, nausea, tiredness, headache or joint and musculoskeletal pain. Most of these side effects of Fulvetraz 250 mg Injection 5 ml do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.

If you are allergic to Fulvestrant or any other medicines, please tell your doctor. Fulvetraz 250 mg Injection 5 ml is not recommended for pregnant women as it may harm an unborn baby. Fulvetraz 250 mg Injection 5 ml is contraindicated for use during lactation. Avoid alcohol consumption while receiving Fulvetraz 250 mg Injection 5 ml. Avoid driving or operating machinery if you feel tired or weak after receiving Fulvetraz 250 mg Injection 5 ml.

Uses of Fulvetraz 250 mg Injection 5 ml

Fulvetraz 250 mg Injection 5 ml is used in the treatment of Breast cancer in postmenopausal women. The detailed uses of Fulvetraz 250 mg Injection 5 ml are as follows:<br/>• Treatment of breast cancer: Fulvetraz 250 mg Injection 5 ml is used in the treatment of hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer in postmenopausal women.<br/>• Treatment of progressed cancer: Fulvetraz 250 mg Injection 5 ml is prescribed when the cancer has progressed following prior endocrine therapy.<br/>

Directions for Use

• Your doctor will decide the dosage and timing of Fulvetraz 250 mg Injection 5 ml based on the stage of cancer and your body's response to the treatment. Usually, it is given every two weeks for the first three doses, then once monthly.• Fulvetraz 250 mg Injection 5 ml will be administered by a doctor or nurse in a medical facility.• Do not self-administer.

Medicinal Benefits

Fulvetraz 250 mg Injection 5 ml contains Fulvestrant, used to treat breast cancer in postmenopausal women. Additionally, Fulvetraz 250 mg Injection 5 ml may be used in combination with palbociclib to treat women with a type of breast cancer called hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer that is locally advanced or has spread to other parts of the body (metastatic).

How Fulvetraz 250 mg Injection 5 ml Works

Fulvetraz 250 mg Injection 5 ml contains Fulvestrant, which works by inhibiting some of the actions of estrogen (female sex hormone which may help cancer cells grow in women with breast cancer) and reducing the amount that is in the body. Thus, it helps in reducing breast cancer tumour growth.

Storage

• Store in a cool and dry place away from sunlight.• Keep Fulvetraz 250 mg Injection 5 ml out of reach and sight of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Fulvetraz 250 mg Injection 5 ml
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

What if I have taken an overdose of Fulvetraz 250 mg Injection 5 ml

As Fulvetraz 250 mg Injection 5 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

If you are allergic to Fulvestrant or any other medicines, please tell your doctor. Fulvetraz 250 mg Injection 5 ml is not recommended for pregnant women as it may harm an unborn baby. Using effective contraception while being treated with Fulvetraz 250 mg Injection 5 ml and for two years after the last dose is advised. Fulvetraz 250 mg Injection 5 ml is contraindicated for use during lactation. Avoid alcohol consumption while receiving Fulvetraz 250 mg Injection 5 ml. Avoid driving or operating machinery if you feel tired or weak after receiving Fulvetraz 250 mg Injection 5 ml.

Drug-Drug Interactions

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FulvestrantFluoroestradiol (18f)
Severe

Drug-Drug Interactions

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FulvestrantFluoroestradiol (18f)
Severe
How does the drug interact with Fulvetraz 250 mg Injection 5 ml:
Coadministration of Fulvetraz 250 mg Injection 5 ml with Fluoroestradiol (18f) can reduce the action of Fluoroestradiol (18f) in detecting cancer.

How to manage the interaction:
Taking Fulvetraz 250 mg Injection 5 ml with Fluoroestradiol (18f) together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fibre-rich foods such as whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks, as they can worsen the symptoms.
  • Maintain a healthy weight and do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Fulvetraz 250 mg Injection 5 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid alcohol consumption while receiving this medicine. If you have any concerns, please discuss them with your doctor.

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Pregnancy

Unsafe

Fulvetraz 250 mg Injection 5 ml is not recommended for use during pregnancy as it may harm the unborn baby. You are advised to use effective contraception while being treated with Fulvetraz 250 mg Injection 5 ml and for two years after your last dose.

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Breast Feeding

Unsafe

Fulvetraz 250 mg Injection 5 ml is contraindicated for use during lactation, or you are recommended to avoid breastfeeding while on treatment with Fulvetraz 250 mg Injection 5 ml.

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Driving

Safe if prescribed

Fulvetraz 250 mg Injection 5 ml usually does not affect your ability to drive or operate machinery. However, avoid driving or operating machinery if you feel tired or weak after receiving Fulvetraz 250 mg Injection 5 ml.

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Liver

Caution

Fulvetraz 250 mg Injection 5 ml is not recommended for patients with severe liver problems. Therefore, if you have liver problems, inform your doctor before receiving Fulvetraz 250 mg Injection 5 ml.

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Kidney

Caution

If you have kidney problems, inform your doctor before receiving Fulvetraz 250 mg Injection 5 ml.

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Children

Unsafe

Fulvetraz 250 mg Injection 5 ml is not recommended for children and adolescents below 18 years of age.

Have a query?

FAQs

Fulvetraz 250 mg Injection 5 ml is used to treat Breast cancer in postmenopausal women.

Fulvetraz 250 mg Injection 5 ml contains Fulvestrant which works by inhibiting some of the actions of estrogen (female sex hormone) and reducing the amount that is in the body. Thus, it helps in reducing breast cancer tumour growth.

Fulvetraz 250 mg Injection 5 ml is not recommended for patients with severe liver problems. Therefore, if you have any liver problems, inform your doctor before receiving Fulvetraz 250 mg Injection 5 ml.

Fulvetraz 250 mg Injection 5 ml may cause weakness or tiredness as a common side effect. However, if weakness persists or worsens, please consult your doctor.

Fulvetraz 250 mg Injection 5 ml contains Fulvestrant, which belongs to a class of medications called estrogen receptor antagonists. It helps to slow or stop the growth of specific breast tumours that depend on estrogen (a female sex hormone) to grow.

Fulvetraz 250 mg Injection 5 ml is administered as a liquid injection into a muscle in the buttocks by a doctor in a medical setting. It is typically injected slowly over 1 to 2 minutes. For the first three doses, you will receive an injection every two weeks (on days 1, 15, and 29). After that, it is usually given once a month. Your doctor will determine the exact schedule based on your condition and how you respond to the medication. The injection will be given as two separate shots (one in each buttock). Please do not self-administer it.

Fulvetraz 250 mg Injection 5 ml may cause common side effects, such as injection site reactions like pain and inflammation, weakness, nausea, tiredness, headache, or joint and musculoskeletal pain in some individuals. Most of these side effects of Fulvetraz 250 mg Injection 5 ml do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - FUL0117

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:05 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/68/pil
  2. https://www.astrazeneca.ca/content/dam/az-ca/downloads/productinformation/faslodex-consumer-information-leaflet-en.pdf
  3. https://www.medsafe.govt.nz/consumers/cmi/f/faslodex.pdf

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