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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Fungofine 50Mg Combipack Infusion is used to treat fungal infections. It contains Micafungin, which belongs to the group of medicines called anti-fungal agents, which are indicated in the treatment of fungal infections caused by fungal or yeast cells called Candida. It is effective in treating systemic infections (those that have penetrated within the body). Micafungin interferes with the production of a part of the fungal cell wall that is necessary for the fungus to survive and grow. Thereby, it helps treat fungal infections.

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Composition :

MICAFUNGIN-50MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Fungofine 50Mg Combipack Infusion

Fungofine 50Mg Combipack Infusion belongs to the group of medicines called anti-fungal agents indicated in the treatment of fungal infections caused by fungal or yeast cells called Candida. It is effective in treating systemic infections (those that have penetrated within the body).

Fungofine 50Mg Combipack Infusion contains Micafungin, which works by interfering with the production of a part of the fungal cell wall that is necessary for the fungus to survive and grow. Thereby, it helps treat fungal infections.

In some cases, Fungofine 50Mg Combipack Infusion may cause injection site reactions, nausea, vomiting, abdominal pain, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if any of the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Fungofine 50Mg Combipack Infusion. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medicines you are taking to rule out any side effects/interactions.

Uses of Fungofine 50Mg Combipack Infusion

Fungofine 50Mg Combipack Infusion is used in the treatment of Fungal infections. The detailed uses of Fungofine 50Mg Combipack Infusion are as follows:

  • Treatment of fungal infections: Fungofine 50Mg Combipack Infusion is used primarily to treat serious fungal infections, especially those caused by Candida species such as candidemia, acute disseminated candidiasis, esophageal candidiasis.
  • Prophylaxis of Candida infections: Fungofine 50Mg Combipack Infusion is used to treat prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation, especially those with neutropenia (low white blood cell count).

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Fungofine 50Mg Combipack Infusion is administered by the doctor or healthcare professional.
  • Do not self-administer.

Key Benefits

Fungofine 50Mg Combipack Infusion contains Micafungin, which belongs to the group of medicines called anti-fungal agents indicated in the treatment of fungal infections caused by fungal or yeast cells called Candida. It is effective in treating systemic infections (those that have penetrated within the body). Fungofine 50Mg Combipack Infusion interferes with the production of a part of the fungal cell wall that is necessary for the fungus to survive and grow. Thereby, it helps treat fungal infections.

How Fungofine 50Mg Combipack Infusion Works

Fungofine 50Mg Combipack Infusion contains Micafungin, which works by interfering with the production of a part of the fungal cell wall that is necessary for the fungus to survive and grow. Thereby, it helps treat fungal infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Fungofine 50Mg Combipack Infusion
  • Eat potassium-rich foods like avocados, bananas, spinach, and potatoes.
  • Stay hydrated by drinking plenty of water.
  • Exercise regularly and maintain healthy weight.
  • Manage stress.
  • Prioritize 7-9 hours of sleep each night to help your body and mind recharge.
  • Avoid smoking and limit intake of caffeine.
  • Practice stress-reducing activities like meditation, yoga, or deep breathing to help calm your mind and body.
  • Avoid stimulants and illegal drugs.
  • Call your doctor if it worsens.
  • Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve cramps.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Fungofine 50Mg Combipack Infusion

As Fungofine 50Mg Combipack Infusion is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Do not use Fungofine 50Mg Combipack Infusion if you are allergic to any of its components. Inform the doctor if you have/had haemolytic anaemia (anaemia due to the breakdown of red blood cells), kidney problems like kidney failure or abnormal kidney function, haemolysis (breakdown of red blood cells), liver problems such as liver failure, hepatitis or abnormal liver function tests. Consult the doctor if you are pregnant or breastfeeding. This medicine may cause severe inflammation/eruption of the skin and mucous membranes (Stevens-Johnson syndrome, toxic epidermal necrolysis).

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Taking Fungofine 50Mg Combipack Infusion and streptozocin together can enhance kidney injury and can cause damage to the ear.

How to manage the interaction:
Taking Streptozocin with Fungofine 50Mg Combipack Infusion is not recommended as it can result in an interaction, it can be taken if a doctor has advised it.
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Coadministration of Sirolimus with Fungofine 50Mg Combipack Infusion can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Fungofine 50Mg Combipack Infusion and sirolimus together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Coadministration of Fungofine 50Mg Combipack Infusion and Iohexol may increase the risk of kidney problems.

How to manage the interaction:
Although taking Fungofine 50Mg Combipack Infusion and Iohexol together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Using arsenic trioxide together with Fungofine 50Mg Combipack Infusion cholesteryl sulfate can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Fungofine 50Mg Combipack Infusion with Arsenic trioxide can result in an interaction, but it can be taken if a doctor has advised it. If you experience irregular heartbeat, feeling suddenly dizzy or lightheaded, fainting, a fast or strong heartbeat, feeling weak or tired, feeling sleepy or confused, muscle pain, or feeling sick to your stomach. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Using foscarnet together with Fungofine 50Mg Combipack Infusion can cause serious side effects to the kidneys. Using these drugs together can also increase the risks of seizures (fits) and an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Fungofine 50Mg Combipack Infusion and Foscarnet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: seizures, an irregular heart rhythm, feeling sick, swelling, sudden weight gain or loss, severe pain in your upper stomach that spreads, strong heartbeats, feeling dizzy, or chest pain. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Coadministration of Fungofine 50Mg Combipack Infusion and Iopromide may increase the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Fungofine 50Mg Combipack Infusion and Iopromide, but it can be taken if prescribed by a doctor. If you notice any changes, like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Coadministration of Fungofine 50Mg Combipack Infusion and Ioversol may increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Fungofine 50Mg Combipack Infusion and Ioversol, but it can be taken if prescribed by a doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Coadministration of Fungofine 50Mg Combipack Infusion and Ioxilan may increase the risk of kidney problem.

How to manage the interaction:
Taking Fungofine 50Mg Combipack Infusion with Ioxilan together can result in an interaction, but it can be taken if a doctor has advised it. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Taking cidofovir with Fungofine 50Mg Combipack Infusion can increase the risk of kidney problems.

How to manage the interaction:
Although taking Fungofine 50Mg Combipack Infusion and cidofovir together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Fungofine 50Mg Combipack Infusion:
Coadministration of Fungofine 50Mg Combipack Infusion and Iodamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Fungofine 50Mg Combipack Infusion and Iodamide, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much you pee. If you notice any changes, let the doctor know. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a balanced diet and maintain a healthy weight.
  • Follow a low-sugar diet.
  • A diet supporting gut health may help prevent infections.
  • Include fresh fruits, vegetables and good fats.
  • Avoid gluten, alcohol, and certain dairy products.

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

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Alcohol

Safe if prescribed

It is not known whether Fungofine 50Mg Combipack Infusion interacts with alcohol. Please consult your doctor.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant. It should be used during pregnancy only if clearly needed.

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Breast Feeding

Consult your doctor

Please consult the doctor if you are breastfeeding. Your doctor will decide if Fungofine 50Mg Combipack Infusion can be administered to lactating mothers.

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Driving

Safe if prescribed

Fungofine 50Mg Combipack Infusion is unlikely to have an effect on driving. However, some people may experience dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Fungofine 50Mg Combipack Infusion.

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Kidney

Consult your doctor

If you have a history of kidney problems, inform the doctor before receiving Fungofine 50Mg Combipack Infusion.

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Children

Safe if prescribed

Please consult the doctor if you have any concerns regarding the usage of Fungofine 50Mg Combipack Infusion in children.

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Heart

Fungofine 50Mg Combipack Infusion should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Fungofine 50Mg Combipack Infusion.

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Geriatrics

Consult your doctor

Fungofine 50Mg Combipack Infusion is generally considered safe when used under medical supervision in geriatric patients. However, please consult your doctor if you have any concerns.

FAQs

Fungofine 50Mg Combipack Infusion is used to treat Fungal infections.

Fungofine 50Mg Combipack Infusion works by causing defects in the fungal cell wall, making them unable to live and grow. Thereby, it helps treat fungal infections.

Fungofine 50Mg Combipack Infusion may cause abnormal blood tests (decreased white/red blood cells and platelets), abnormal liver function tests (increased alkaline phosphatase, increased alanine aminotransferase, increased aspartate aminotransferase) or abnormal kidney function tests (increased urea in the blood, increased blood creatinine). If you are undergoing any tests, inform the doctor that you are on treatment with Fungofine 50Mg Combipack Infusion.

The efficacy of Fungofine 50Mg Combipack Infusion against infections caused by fungi other than Candida has not been established. Consult the doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - FUN0148

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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