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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Gedrot MF 40mg/250mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. It contains Drotaverine and Mefenamic acid, which works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Also, it blocks the effect of chemical messengers that cause pain and inflammation. In some cases, it may cause common side effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Not Returnable

About Gedrot MF 40mg/250mg Tablet

Gedrot MF 40mg/250mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Gedrot MF 40mg/250mg Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Gedrot MF 40mg/250mg Tablet helps in relieving pain.

You are advised to take Gedrot MF 40mg/250mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have/had asthma, peptic ulcers, porphyria, or bleeding problems. Consult your doctor if you are pregnant or breastfeeding. Gedrot MF 40mg/250mg Tablet may cause dizziness, so drive with caution. Gedrot MF 40mg/250mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Gedrot MF 40mg/250mg Tablet

Gedrot MF 40mg/250mg Tablet is used in pain management treatments. The detailed uses of Gedrot MF 40mg/250mg Tablet are as follows:
• Relief from Menstrual Cramps: Gedrot MF 40mg/250mg Tablet is frequently used to reduce extreme menstrual pain, which eases period discomfort and cramping.
• Abdominal Pain Treatment: It can help relieve muscle spasms in the gastrointestinal tract and effectively helps to manage abdominal pain due to various conditions.
• Postoperative Pain Management: Gedrot MF 40mg/250mg Tablet is occasionally recommended to help manage pain after surgery, especially in cases when muscle spasms are present.
• Improving Gastrointestinal Conditions: Gedrot MF 40mg/250mg Tablet can also be used to alleviate pain and discomfort caused by gastrointestinal conditions including irritable bowel syndrome.

Directions for Use

Take Gedrot MF 40mg/250mg Tablet with food to prevent stomach upset. Swallow Gedrot MF 40mg/250mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Gedrot MF 40mg/250mg Tablet is a combination of two drugs: Drotaverine and Mefenamic acid. Gedrot MF 40mg/250mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Drotaverine is an antispasmodic that reduces calcium reuptake by the cells, thereby correcting the calcium levels in the body and relieving contractions associated with smooth muscles. Mefenamic acid is an NSAID which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Gedrot MF 40mg/250mg Tablet helps in relieving pain.

How Gedrot MF 40mg/250mg Tablet Works

Gedrot MF 40mg/250mg Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Gedrot MF 40mg/250mg Tablet helps in relieving pain.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Gedrot MF 40mg/250mg Tablet

Do not take more than the prescribed dose of Gedrot MF 40mg/250mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Gedrot MF 40mg/250mg Tablet if you are allergic to any of its contents. Inform your doctor if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. If you have had any recent heart surgery, do not take Gedrot MF 40mg/250mg Tablet unless prescribed by the doctor, as Gedrot MF 40mg/250mg Tablet may increase the risk of heart attack or stroke. Inform your doctor if you have/had asthma, peptic ulcers, porphyria, bleeding problems, liver or kidney impairment. Consult your doctor if you are pregnant or breastfeeding. Gedrot MF 40mg/250mg Tablet may cause dizziness, so drive only if you are alert. Gedrot MF 40mg/250mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol as it could lead to increased drowsiness and may increase the risk of stomach bleeding. Stop taking Gedrot MF 40mg/250mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Gedrot MF 40mg/250mg Tablet unless prescribed.

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Co-administration of Gedrot MF 40mg/250mg Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Gedrot MF 40mg/250mg Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Coadministration of Gedrot MF 40mg/250mg Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Gedrot MF 40mg/250mg Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidSirolimus
Severe
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Co-administration of Gedrot MF 40mg/250mg Tablet with Sirolimus can increase the risk or severity of kidney disorders.

How to manage the interaction:
Taking Gedrot MF 40mg/250mg Tablet with Sirolimus together can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidWarfarin
Severe
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Coadministration of Gedrot MF 40mg/250mg Tablet with Warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Gedrot MF 40mg/250mg Tablet with Warfarin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Mefenamic acidPiroxicam
Severe
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Coadministration of Gedrot MF 40mg/250mg Tablet with Piroxicam can increase the risk side effects such as inflammation(swelling with redness and pain), bleeding, ulceration, and perforation leading to serious blood loss.

How to manage the interaction:
Taking Gedrot MF 40mg/250mg Tablet with Piroxicam together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidTeriflunomide
Severe
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Teriflunomide may cause liver damage and taking it with Gedrot MF 40mg/250mg Tablet may increase that risk.

How to manage the interaction:
Although taking Gedrot MF 40mg/250mg Tablet and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away - liver problems, fever, feeling cold, pain in your joints, swelling, bruises, rash, itchy skin, not feeling hungry, feeling tired, feeling sick, throwing up, dark urine, or bleeding. Do not discontinue any medications without consulting a doctor.
Mefenamic acidNaproxen
Severe
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Coadministration of Gedrot MF 40mg/250mg Tablet with Naproxen can increase the risk or severity of stomach bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Gedrot MF 40mg/250mg Tablet with Naproxen together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidFlurbiprofen
Severe
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Co-administration of Gedrot MF 40mg/250mg Tablet with Flurbiprofen can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Gedrot MF 40mg/250mg Tablet with Flurbiprofen together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of dizziness, lightheadedness, unusual bleeding or bruising, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMethotrexate
Severe
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Coadministration of Gedrot MF 40mg/250mg Tablet with Methotrexate may increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between Gedrot MF 40mg/250mg Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Mefenamic acidPrasugrel
Severe
How does the drug interact with Gedrot MF 40mg/250mg Tablet:
Co-administration of Gedrot MF 40mg/250mg Tablet with Prasugrel can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Gedrot MF 40mg/250mg Tablet with Prasugrel together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Gedrot MF 40mg/250mg Tablet Substitute

Substitutes safety advice
  • Spasmoquick D 40mg/250mg Tablet

    by Others

    26.91per tablet
  • Rotaspas M 40 mg/250 mg Tablet

    by Others

    5.45per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Gedrot MF 40mg/250mg Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Gedrot MF 40mg/250mg Tablet if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Gedrot MF 40mg/250mg Tablet may cause drowsiness. Drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Gedrot MF 40mg/250mg Tablet should not be given to children as the safety and effectiveness were not established.

FAQs

Gedrot MF 40mg/250mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery.

Gedrot MF 40mg/250mg Tablet contains Drotaverine and Mefenamic acid. Drotaverine works by relieving contractions associated with smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

Diarrhoea might be a side-effect of Gedrot MF 40mg/250mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

Dry mouth could be a side-effect of Gedrot MF 40mg/250mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not take Gedrot MF 40mg/250mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Take Gedrot MF 40mg/250mg Tablet only for as long as your doctor has prescribed it.

Gedrot MF 40mg/250mg Tablet is generally prescribed for short durations and can be discontinued after pain relief. However, you are advised to continue taking Gedrot MF 40mg/250mg Tablet for as long as your doctor has prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Gedrot MF 40mg/250mg Tablet.

Gedrot MF 40mg/250mg Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Gedrot MF 40mg/250mg Tablet only as prescribed, and do not overdose.

Gedrot MF 40mg/250mg Tablet may cause dizziness, so drive with caution and only if you are alert. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Stop taking Gedrot MF 40mg/250mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

No, do not take Gedrot MF 40mg/250mg Tablet on an empty stomach. Take it with food to prevent stomach upset.

Gedrot MF 40mg/250mg Tablet usually starts working within an hour. However, this might vary individually based on the physical condition.

The doctor will determine the daily dose of Gedrot MF 40mg/250mg Tablet based on your condition. Please consult the doctor if you have any concerns.

Gedrot MF 40mg/250mg Tablet is a combination medicine containing Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). It is used to relieve abdominal pain associated with various conditions.

Yes, Gedrot MF 40mg/250mg Tablet is safe if taken in the dose and duration prescribed by the doctor.

Yes, Gedrot MF 40mg/250mg Tablet may cause nausea and vomiting as a side effect. If you have nausea and vomiting, get fresh air, take sips of water regularly, and eat smaller, frequent meals. Consult the doctor if the condition persists or worsens.

No, do not take a higher than the recommended dose of Gedrot MF 40mg/250mg Tablet as it may cause overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Store Gedrot MF 40mg/250mg Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.

Yes, Gedrot MF 40mg/250mg Tablet can be taken with food. Taking Gedrot MF 40mg/250mg Tablet with food helps prevent stomach upset.

Common side effects of Gedrot MF 40mg/250mg Tablet are gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Gedrot MF 40mg/250mg Tablet can be used during pregnancy or breastfeeding if advised by the doctor. The doctor will prescribe Gedrot MF 40mg/250mg Tablet only if the benefits outweigh the risks.

Do not take Gedrot MF 40mg/250mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Take Gedrot MF 40mg/250mg Tablet only for as long as your doctor has prescribed it.

If you miss a dose of Gedrot MF 40mg/250mg Tablet, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Country of origin

India
Other Info - GE86631

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