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  1. Home
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  3. Gleeza Mex XR Tablet 10's

Prescription drug
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Gleeza Mex XR Tablet 10's, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Gleeza Mex XR Tablet 10's is used to treat Type 2 diabetes. It contains Gliclazide and Metformin, which acts by increasing the amount of insulin released by the pancreas. Also, it lowers the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin. It shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, a healthy diet etc. A common side effect of this medicine is hypoglycaemia (low blood glucose levels) characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin etc. So, to avoid hypoglycaemia, you should not miss meals and also should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

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Composition :

GLICLAZIDE-60MG + METFORMIN-500MG

Manufacturer/Marketer :

Efrosine Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gleeza Mex XR Tablet 10's

Gleeza Mex XR Tablet 10's is used to treat type 2 diabetes mellitus. Type 2 diabetes develops when the body does not produce enough insulin or when your body's insulin does not work as well as it should. It can also develop if the body produces too much glucagon.

Gleeza Mex XR Tablet 10's is a combination of Gliclazide and Metformin. This medicine works by increasing the amount of insulin released by the pancreas and thus results in decreased blood sugar levels in the body. It also works by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin.

Not everyone who is taking Gleeza Mex XR Tablet 10's will get these side effects. In some cases, you may experience certain common side effects, such as stomach ache or indigestion, nausea, vomiting, and constipation. Most of these side effects do not require medical attention and resolve gradually over time. However, please consult your doctor if you experience these side effects persistently.

Gleeza Mex XR Tablet 10's should be taken with food to avoid an upset stomach. It is advised to take it at the same time each day for best results. For better advice, your doctor will determine the appropriate dose, which can change quickly depending on your condition. Do not skip your meals, and also carry a form of sugar with you to prevent low blood sugar levels.

Do not take Gleeza Mex XR Tablet 10's if you are allergic to any of its components, or if you have diabetic ketoacidosis (excess acids in your blood). Gleeza Mex XR Tablet 10's should not be stopped even if you feel better without consulting your doctor, as sugar levels may change. Consult the doctor if you are pregnant or planning to get pregnant or breastfeeding. Avoid alcohol consumption while taking Gleeza Mex XR Tablet 10's, as it might increase the side effects (hypoglycemia). 

Uses of Gleeza Mex XR Tablet 10's

Gleeza Mex XR Tablet 10's is used in the treatment of Type 2 diabetes mellitus. The detailed uses of Gleeza Mex XR Tablet 10's are as follows:

  • Diabetes Management: Gleeza Mex XR Tablet 10's is frequently prescribed to manage blood sugar levels in individuals with type 2 diabetes.
  • Cardiovascular Health: By enhancing blood sugar control, Gleeza Mex XR Tablet 10's contributes to better cardiovascular health and reduces the risk of heart disease in diabetic patients.
  • Improving Energy Levels: Stabilising blood sugar levels with Gleeza Mex XR Tablet 10's helps boost energy levels and supports overall well-being in those managing diabetes.

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Directions for Use

  • Gleeza Mex XR Tablet 10's should be taken with food to avoid stomach upset.
  • It is usually taken twice daily at the same time each day or as prescribed by your doctor.
  • Swallow Gleeza Mex XR Tablet 10's as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

  • Gleeza Mex XR Tablet 10's plays a vital role in decreasing the blood sugar level in the body as metformin lowers glucose production in the liver, whereas the other increases the amount of insulin released by the pancreas.
  • Gleeza Mex XR Tablet 10's also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), loss of sensation in your hands and feet (diabetic neuropathy) or even loss of the foot.
  • Gleeza Mex XR Tablet 10's also helps to reduce your chance of having a heart attack or stroke.
  • Being a combination of two drugs, it reduces the need to take multiple pills and hence makes it easier to remember to take the drugs.
  • The strict control of blood sugars is especially important to mention the many disabling side effects of diabetes.
  • Gleeza Mex XR Tablet 10's shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, a healthy diet, etc. 

How Gleeza Mex XR Tablet 10's Works

Gleeza Mex XR Tablet 10's is a combination of two anti-diabetic drugs: Gliclazide and Metformin. Gliclazide works by increasing the amount of insulin released by the pancreas. On the other hand, Metformin, works by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin. In a nutshell, the two medicines prevent blood glucose levels from rising to very high levels, thus keeping your Diabetes under control. Gleeza Mex XR Tablet 10's act together to keep your blood sugar levels under check.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Gleeza Mex XR Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Gleeza Mex XR Tablet 10's

Do not take more than the prescribed dose of Gleeza Mex XR Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Gleeza Mex XR Tablet 10's if you are allergic to any of its components. Also this medicine is not recommended in conditions like type 1 diabetes, diabetic pre-coma or coma, severe liver or kidney disease.
  • Inform the doctor if you have/had any medical history of heart, liver, and kidney diseases, glucose-6-phosphate dehydrogenase (G6PD) deficiency (abnormality of red blood cells), and hemolytic anemia.
  • Gleeza Mex XR Tablet 10's, when used with insulin, may extremely lower the blood sugar level, leading to a hypoglycemic condition, which can be fatal.
  • Inform your doctor if you are pregnant, planning for a pregnancy or breastfeeding before starting the treatment.
  • Gleeza Mex XR Tablet 10's may lower vitamin B12 levels, so try to have annual blood tests and vitamin tests.
  • Gleeza Mex XR Tablet 10's may lower your thyroid-stimulating hormone (TSH), so an annual check-up of TSH is suggested.
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).
  • Be alert for signs of low blood sugar (hypoglycemia), such as sweating, dizziness, dry mouth, dry skin, fast heartbeat, shivering, intense thirst, or frequent urination.

Drug-Drug Interactions

verifiedApollotooltip
MetforminIocarmic acid
Critical
MetforminMetrizamide
Critical

Drug-Drug Interactions

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MetforminIocarmic acid
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Gleeza Mex XR Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminMetrizamide
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Gleeza Mex XR Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIoxitalamic acid
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Gleeza Mex XR Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Iopydol with Gleeza Mex XR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Gleeza Mex XR Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Ioglycamic acid with Gleeza Mex XR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Iopamidol with Gleeza Mex XR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Ioversol with Gleeza Mex XR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIobenzamic acid
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Gleeza Mex XR Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Gleeza Mex XR Tablet:
Co-administration of Iotroxic acid with Gleeza Mex XR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gleeza Mex XR Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest at least 150 minutes of moderate-intensity physical activity and 15 minutes of high-intensity exercise weekly.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with whole grain foods and increase intake of fruits, veggies, and other fibre-enriched foods.
  • Reduce saturated fat intake (or hidden fats) in food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control pressure related to blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
  • Keep your blood pressure as normal (120/80) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Gleeza Mex XR Tablet 10's to avoid unpleasant side-effects.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Gleeza Mex XR Tablet 10's; your doctor will decide whether Gleeza Mex XR Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Caution

Gleeza Mex XR Tablet 10's may cause hypoglycaemia (low blood sugar levels), whose symptoms include unusual sleepiness, shivering, palpitations, sweating etc. This may affect your ability to drive. Use caution while driving or doing anything that requires concentration.

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Liver

Caution

Tell your doctor before prescribing the Gleeza Mex XR Tablet 10's if you have a history of liver disease. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Tell your doctor before receiving the Gleeza Mex XR Tablet 10's if you have a history of kidney disease. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Unsafe

The safety and efficacy of Gleeza Mex XR Tablet 10's in children have not been established. Gleeza Mex XR Tablet 10's is not recommended in children.

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Heart

Please consult your physician if you have any heart-related problems before taking Gleeza Mex XR Tablet 10's.

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Geriatrics

Consult your doctor

Your doctor will recommend Gleeza Mex XR Tablet 10's if needed in the geriatric population. Please consult your doctor.

FAQs

Gleeza Mex XR Tablet 10's is used to treat Type 2 diabetes.

Gleeza Mex XR Tablet 10's is a combination of two anti-diabetic drugs: Gliclazide and‚ Metformin. Gliclazide works by increasing the amount of insulin released by the pancreas. On the other hand, Metformin works by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin. In a nutshell, the two medicines prevent blood glucose levels from rising to very high levels, thus keeping your diabetes under control.

Hypoglycemia refers to low blood sugar levels and it is one of the side effects of Gleeza Mex XR Tablet 10's. Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. It is important to regularly monitor blood sugar levels.

No, Gleeza Mex XR Tablet 10's should not be used with other anti-diabetic medications as it may cause hypoglycemia (lowering of blood sugar level).

If you feel thirsty after taking Gleeza Mex XR Tablet 10's, it may be because of dehydration as Gleeza Mex XR Tablet 10's can lead to loss of fluids. Increase intake of fluids, if even then you feel thirsty please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Plot No 5332, EWS B Type Phase 1 & 2, Ayapakkam, Chennai, 600077
Other Info - GLE0153

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 14, 2025 | 1:12 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/5883/smpc
  2. https://www.medicines.org.uk/emc/files/pil.5883.pdf
  3. https://www.mrmed.in/molecule/gliclazide-metformin?srsltid=AfmBOorU4Y0TfrYa_n75Ue7WscJP-W-0i1pptwmIGMTUZOBSU7QlEZkC

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