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Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is used for weight management in people with obesity or overweight when combined with a reduced-calorie diet and increased physical activity. By supporting weight loss and improving metabolic health, Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may help lower the risk of serious heart-related problems, such as heart attack and stroke, in certain individuals with heart disease. Common side effects may include nausea, diarrhoea, vomiting, constipation, abdominal pain, headache, fatigue, dizziness, bloating, and heartburn. 

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Glenmark Pharmaceutical Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is indicated for weight management when used together with a reduced-calorie diet and increased physical activity in individuals with obesity. It also helps to lower the risk of serious heart-related problems, such as heart attack and stroke, in people with obesity or overweight and established heart disease.

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's contains semaglutide, a GLP-1 receptor agonist that mimics a natural hormone involved in appetite regulation. It works by slowing the emptying of food from the stomach, increasing feelings of fullness, and reducing hunger, which helps lower calorie intake and support weight management. It also helps the body regulate blood sugar levels and supports overall metabolic health.

Additionally, by supporting weight loss and improving metabolic health, Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may help lower the risk of serious heart-related problems, such as heart attack and stroke, in people who are overweight or obese and have heart disease.

In some cases, Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may cause side effects such as nausea, vomiting, diarrhoea, constipation, abdominal discomfort, dizziness, or altered taste. Talk to your doctor if the side effects persist or worsen.

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is available in a pre-filled multi-dose pen that allows flexible dosing. It features an easy-to-use dialer for accurate dose delivery and is designed for convenient self-administration. Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is not recommended for use in children, during pregnancy, or while breastfeeding.

Uses of Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is used to treat various medical conditions. The detailed uses are as follows:

  • Chronic weight management: Used in individuals with obesity or overweight to help achieve and maintain weight loss when combined with a reduced-calorie diet and increased physical activity.
  • Cardiovascular risk reduction: Helps to lower the risk of serious heart-related problems, such as heart attack and stroke, in people with obesity or overweight and heart disease.

Key Benefits

  • Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's contains semaglutide, a GLP-1 receptor agonist that mimics a naturally occurring hormone that regulates appetite and digestion.
  • It helps reduce calorie intake by slowing gastric emptying, increasing feelings of fullness, and decreasing hunger and food cravings, thereby supporting weight loss.
  • Promotes long-term weight management when combined with a reduced-calorie diet and physical activity, helping patients achieve and maintain a healthy body weight.
  • Improves metabolic health by aiding in better blood sugar control, lowering cholesterol levels, and reducing blood pressure in patients with obesity or overweight.
  • Reduces cardiovascular risk by lowering the chance of major heart-related events (such as heart attack or stroke) in adults with established heart disease who are overweight or obese.

Directions for Use

  • A qualified healthcare professional will instruct you on how to administer Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's.
  • It is a once-weekly subcutaneous injection in the abdomen, thigh, or upper arm. It should not be injected intravenously or intramuscularly.
  • Kindly do not self-administer without proper training and medical guidance.

How Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's Works

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's contains semaglutide, which acts like a natural hormone in the body that helps control appetite. It works by slowing the movement of food from the stomach, helping you feel full for longer and reducing hunger. This can help you eat less and support weight loss. It also helps the body control blood sugar levels. By supporting weight loss and improving overall health, Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may help lower the risk of serious heart-related problems, such as heart attack and stroke, in certain individuals.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's. It could lead to increased adverse events.

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Pregnancy

Unsafe

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's should not be used during pregnancy as there is a potential risk of harm to the unborn baby. Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is not recommended for women who are pregnant, planning to conceive soon, or not using reliable contraception during therapy.

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Breast Feeding

Unsafe

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is not recommended during breastfeeding as its safety is not established.

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Driving

Caution

Generally does not impair ability to drive; however, dizziness or low blood sugar (if combined with other drugs) may affect alertness.

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Liver

Caution

Inform your doctor before receiving Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's if you have a pre-existing or a history of liver disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's if you have a pre-existing or a history of kidney disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Consult your doctor

It is not recommended for use in children under 18 years of age, as the safety and efficacy have not been established.

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Heart

Safe if prescribed

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is used in patients with heart disease to help reduce the risk of major adverse events such as heart attack and stroke. However, people who have an irregular heartbeat or a very fast heart rate may need closer monitoring during treatment to make sure the medicine is safe and working properly.

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Geriatrics

Caution

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's should be used with caution in elderly patients, as it may be associated with a higher risk of fractures.

What if I have taken an overdose of Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's

As Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is supplied in a pre-filled injection pen, the risk of accidental overdose is low when used as directed. However, an overdose may occur if more than the prescribed dose is taken, such as accidentally administering an extra dose. Symptoms of overdose may include severe nausea, vomiting, and other gastrointestinal symptoms. If an overdose is suspected, seek medical attention immediately. Patients should be monitored for symptoms, and appropriate supportive treatment should be provided.

Diet & Lifestyle Advise

  • Follow a calorie-controlled, balanced diet as advised by your doctor or dietitian. This is essential for weight loss and to maximise the effect of Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's.
  • Choose high-fibre, nutrient-dense foods like vegetables, fruits, whole grains, and lean proteins. These help you feel full longer and support blood sugar control.
  • Avoid high-sugar and high-fat foods, which can slow weight loss and affect blood sugar levels. Limit processed snacks, fried foods, and sugary drinks.
  • Eat smaller, frequent meals and chew slowly to reduce nausea and discomfort, as Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's slows stomach emptying.
  • Stay hydrated by drinking plenty of water throughout the day. This helps prevent dehydration, especially if you experience vomiting or diarrhoea, which are possible side effects.
  • Limit or avoid alcohol, as it can increase the risk of low blood sugar (if you have diabetes or take insulin/sulfonylureas) and may worsen gastrointestinal side effects.
  • Be physically active for at least 150 minutes a week (e.g., brisk walking, cycling, swimming), as regular exercise enhances weight loss and improves blood pressure, cholesterol, and blood sugar.
  • Monitor your blood sugar regularly if you have type 2 diabetes or are taking other diabetes medications, as weight loss and Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may change your medication needs.
  • Keep regular follow-up appointments so your doctor can track your progress, adjust your dose if necessary, and check for side effects or complications.
  • Adopt long-term healthy habits, to help keep the weight off after stopping Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's, continue following a healthy diet and regular physical activity.

Have a query?

How Soon It Starts Working

  • The time required for Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's to start to work: Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's ideally shows its action within 1 hour after administration.
  • The time for which the effects of Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's last: The duration of action for Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is about 24-48 hours.

What if you forget to take Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's

If you miss a dose of Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's, consult your doctor or healthcare professional. They will reschedule the missed dose and may adjust the timing of your next doses if necessary.

Storage

• Store in a refrigerator (2°C to 8°C).
• Do not freeze or use if previously frozen.
• Keep this medicine out of the sight and reach of children.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Do not use Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's if you or a close family member has ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or if you have ever experienced a severe allergic reaction to semaglutide or any of its ingredients.
  • Let your doctor know about all your medical conditions before using Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's, including if you have or have ever had pancreatitis (inflamed pancreas), gallbladder problems or gallstones, kidney disease, severe digestive issues like gastroparesis (slow stomach emptying), diabetic eye disease (retinopathy), or any mental health concerns such as depression or suicidal thoughts.
  • Inform your doctor about every medicine, vitamin, or herbal supplement you are taking, as Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may change how other medicines are absorbed. For instance, using Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's with insulin or sulfonylureas can increase the risk of low blood sugar, so your doctor may need to adjust other treatments.
  • Do not use Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's if you are pregnant, planning pregnancy, or breastfeeding. Stop the medicine at least 2 months before trying to conceive due to its long-lasting effect in the body. If you find out you are pregnant while using Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's, stop it immediately and call your doctor.
  • It is not recommended for use in children under 18 years of age.
  • Contact your doctor immediately if you experience any severe or persistent side effects, such as ongoing stomach pain (which may signal pancreatitis), signs of an allergic reaction (swelling, rash, difficulty breathing), severe vomiting or diarrhoea leading to dehydration, or mood changes such as depression or suicidal thoughts.

verifiedApollotooltip

Drug-Drug Interactions: Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's potentially interacts with certain medications used to treat certain cancers (e.g., bexarotene, capivasertib), certain general anaesthetics (e.g., desflurane, enflurane, etomidate, fospropofol, halothane, isoflurane, ketamine), antibiotics (e.g., gatifloxacin), certain insulin or sulfonylureas (e.g., glimepiride, glyburide) and certain GLP‑1 receptor agonists or similar weight-loss medications (e.g., liraglutide, tirzepatide).

Drug-Food Interactions: There are no significant food restrictions with Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's. However, limit alcohol intake as it can worsen nausea and vomiting and may increase the risk of low blood sugar, particularly if you are using other diabetes medicines.

Drug-Disease Interactions: If you have a history of suicidal behaviour and ideation, thyroid cancer, hypoglycemia, pancreatitis, retinopathy and GI adverse reactions. Inform your doctor before starting treatment with Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's. These conditions may require close monitoring or adjustments to your therapy.

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's is used for weight management in people with obesity when combined with a reduced-calorie diet and increased physical activity. It may also help lower the risk of serious heart-related problems, such as heart attack and stroke, in people who are overweight or obese and have heart disease.

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's works by acting like a natural hormone in the body that helps control appetite. It helps you feel full for longer, reduces hunger, and slows down the movement of food from the stomach. This can help you eat less and manage your weight more effectively. It also helps the body regulate blood sugar levels. By supporting weight loss and improving metabolic health, Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may help lower the risk of serious heart-related problems, such as heart attack and stroke, in certain individuals with heart disease.

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may cause side effects such as nausea, diarrhoea, vomiting, constipation, abdominal pain, headache, fatigue, upset stomach, dizziness, bloating, belching, low blood sugar (in people with type 2 diabetes), gas, gastroenteritis (stomach flu), heartburn, runny nose, and sore throat. Side effects may vary from person to person depending on individual factors. Consult your doctor if any side effects persist, worsen, or become bothersome.

Pancreatitis (inflammation of the pancreas) is a possible side effect of Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's. Stop using Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's and contact your healthcare provider immediately if you develop severe, persistent stomach pain, with or without nausea or vomiting. The pain may also spread from your abdomen to your back.

Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's may increase the risk of low blood sugar, especially in people with type 2 diabetes who also take insulin or certain diabetes medicines such as sulfonylureas. Checking your blood sugar levels before starting Glipiq 0.25mg/0.5mg (2mg/1.5ml) Injection 1's and during treatment is recommended. Symptoms of low blood sugar may include dizziness, sweating, shakiness, blurred vision, weakness, hunger, headache, anxiety, irritability, confusion, drowsiness, a fast heartbeat, slurred speech, or feeling jittery. If you experience these symptoms, contact your healthcare provider for advice on managing low blood sugar.

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Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - GLI3319
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