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compositionComposition:GLIBENCLAMIDE-5MG
prescription
Prescription Medicine
info
Glipol Tablet

Glipol Tablet is used to treat type-2 diabetes. It contains Glibenclamide, which acts by increasing the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control. It shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, a healthy diet, etc. A common side effect of this medicine is low blood glucose levels characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. To avoid hypoglycaemia, you should not miss meals and should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GLIBENCLAMIDE-5MG

Manufacturer/Marketer :

Medipol Pharmaceutical India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Glipol Tablet

Glipol Tablet is an oral prescription medication used to manage and lower blood sugar levels in adults with type 2 diabetes. It is prescribed when diet, exercise, and lifestyle changes alone are not enough to control blood sugar. By keeping blood sugar in a healthy range, this medication helps prevent serious long-term complications of diabetes.

To get the best results, you must take Glipol Tablet consistently every day exactly as your doctor directs. It is typically taken once daily, right before or with your breakfast or your first main meal of the day. Combining this medication with a balanced diet and regular physical activity is essential for managing your condition effectively.

While taking Glipol Tablet, some people may experience mild side effects like nausea or a temporary upset stomach. The most common risk is low blood sugar, which can cause shakiness, sweating, or dizziness. If you experience severe symptoms of low blood sugar, yellowing of your skin or eyes, or severe skin rashes, seek medical attention immediately.

Do not take this if you have type 1 diabetes or diabetic ketoacidosis, which is a serious complication of diabetes. It is also important to tell your doctor before starting this medicine if you have kidney or liver problems or a genetic condition called 'G6PD deficiency'. Your doctor will help determine if this medication is safe for you.

Glipol Tablet can interact with alcohol, which may cause your blood sugar to drop dangerously low or lead to flushing and headaches. If you are pregnant, planning to become pregnant, breastfeeding, or an elderly individual, consult your doctor before using this medicine, as alternative treatments may be safer.

Uses of Glipol Tablet

Glipol Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Glipol Tablet are as follows:

  • Type 2 Diabetes Mellitus: Glipol Tablet is used to improve blood sugar control in adults with type 2 diabetes when dietary changes and physical exercise alone do not provide adequate control.

Key Benefits

Managing your blood sugar with Glipol Tablet offers several important health benefits that help you feel better and protect your long-term wellness:

  • Prevention of diabetes complications: By keeping your blood sugar stable, this medicine reduces the risk of serious complications like kidney damage, nerve pain, blindness, and cardiovascular issues.
  • More consistent daily energy: Stable blood sugar levels help prevent the extreme fatigue, sluggishness, and frequent urination often caused by high glucose levels, allowing you to go about your day with more consistent energy.
  • Effective blood sugar control: It provides a reliable way to manage daily blood sugar spikes, especially after meals, when combined with a healthy diet.
Side effects of Glipol Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Eat smaller meals, more often throughout the day to reduce stomach pressure.
  • Identify and avoid trigger foods like spicy, greasy foods or carbonated drinks.
  • Chew your food thoroughly to help digestion.
  • Make sure your intake of fiber is balanced to promote healthy digestion.
  • Take your medicine with food to minimize stomach irritation.
  • Consider over-the-counter antacids to neutralize stomach acid.
  • Drink lots of water throughout the day.
  • Practice relaxation methods to reduce stress as it can worsen digestive issues.
  • If the epigastric fullness persists or worsens, consult your doctor to discuss possible dosage adjustments or switching to alternative medicine.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

For the best and safest results, always follow these step-by-step instructions on how to take Glipol Tablet:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • Take your dose immediately before or during your breakfast or your first main meal of the day. Never take this medication on an empty stomach if you plan to skip a meal, as this can cause a severe drop in blood sugar.
  • Try to take your medicine at the same time every day to establish a consistent routine.
  • Always follow your doctor's exact instructions regarding your specific schedule. Do not adjust your dose without consulting your healthcare provider first.
     

How Glipol Tablet Works

Glipol Tablet belongs to a class of medications known as sulfonylureas. It works primarily by targeting the beta cells in your pancreas, which are responsible for producing insulin. The medication stimulates these cells to release more insulin into your bloodstream, helping your body process and remove sugar from the blood more effectively. Glipol Tablet blood sugar-lowering effect is mainly due to its ability to increase insulin secretion from the pancreas. By lowering the amount of sugar circulating in your blood, it helps maintain a healthier glucose balance and reduces the blood sugar spikes that can contribute to long-term diabetes complications. Glipol Tablet has a relatively long duration of action, with effects that may last up to 24 hours. Because of this prolonged action, it is associated with a higher risk of hypoglycaemia compared with some shorter-acting sulfonylureas, making regular meals and blood sugar monitoring especially important.
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Alcohol

Unsafe

Glipol Tablet should not be taken until prescribed if you are taking alcohol. Taking Glipol Tablet with alcohol can cause hypoglycemia. So, keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

As the data around the use of Glipol Tablet in pregnant women is limited, the use of Glipol Tablet in pregnancy is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

Tell your doctor if you are breastfeeding. Do not breastfeed while you are taking Glipol Tablet without advice from your doctor.

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Driving

Caution

Glipol Tablet may cause hypoglycemia (low blood sugar levels) whose symptoms include unusual sleepiness, shivering, palpitations, sweating, etc. This may affect your ability to drive. Use caution while driving or doing anything that requires concentration or mental alertness.

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Liver

Caution

Glipol Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor, depending on your liver function tests.

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Kidney

Unsafe

Glipol Tablet is unsafe, especially if you have a history of kidney diseases/conditions.

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Children

Unsafe

Glipol Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Glipol Tablet have not been established in children due to limited evidence. So, only take Glipol Tablet if the doctor has prescribed you.

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Heart

Consult your doctor

Please consult your doctor before using Glipol Tablet if you have pre-existing heart problems. Your doctor will prescribe Glipol Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Glipol Tablet to geriatric patients. Your doctor will prescribe Glipol Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Glipol Tablet

Do not take more than the prescribed dose of Glipol Tablet as it may cause overdose resulting in severe low blood sugar. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eat meals regularly: Do not skip meals, especially after taking your medication. Skipping meals while taking Glipol Tablet greatly increases the risk of low blood sugar.
  • Carry fast-acting sugar: Always keep a source of fast-acting sugar with you, such as glucose tablets, fruit juice, or hard candy, to treat sudden low blood sugar symptoms.
  • Monitor blood sugar: Check your blood sugar levels regularly as advised by your doctor, especially during times of stress, illness, or changes in exercise.
  • Exercise safely: Engage in moderate physical activity daily, but check your blood sugar before and after exercising. Have a carbohydrate snack nearby in case your blood sugar drops during physical activity.

Have a query?

How Soon It Starts Working

The time required for Glipol Tablet to start to work: Glipol Tablet ideally shows its action within 15 to 60 minutes after administration. The time for which the effects of Glipol Tablet last: The effect of Glipol Tablet lasts for 24 hours.

What if you forget to take Glipol Tablet

If you miss a dose of Glipol Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Glipol Tablet tablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F). •Keep the medicine in its original container to protect it from direct light, heat, and moisture.

Drug Warnings

  • Always inspect the packaging and tablets before use to ensure they have not expired or been damaged.
  • Be aware that alcohol can unpredictably alter your blood sugar levels and increase the risk of severe low blood sugar or cause flushing and sweating.
  • Wear a medical identification bracelet or carry a card in your wallet stating that you have diabetes and are taking Glipol Tablet.
  • Avoid driving or operating machinery if you feel dizzy, shaky, or weak, as these are signs of low blood sugar.
  • Inform any healthcare professional you visit, including dentists and surgeons, that you are taking this medication before undergoing any procedures.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Pain relievers (NSAIDs): May increase the risk of low blood sugar when combined with Glipol Tablet.
  • Beta-blockers: Can mask the warning signs of low blood sugar, such as a rapid heart rate.
  • Water pills (diuretics) and steroids: May decrease the effectiveness of Glipol Tablet, causing your blood sugar to rise.
  • Other diabetes medicines: Combining these can significantly increase the risk of low blood sugar.

Drug-Food Interactions

  • Alcohol: Drinking alcohol while taking this medicine can lead to severe low blood sugar or an unpleasant physical reaction, including headaches and flushing.

Drug-Disease Interactions

  • Type 1 Diabetes and Diabetic Ketoacidosis: Do not take this medicine if you have these conditions, as it is not effective and can be dangerous.
  • Severe Kidney or Liver Disease: These conditions can increase the risk of the drug building up in your body, leading to severe and prolonged low blood sugar.
  • G6PD Deficiency: Taking this medicine with this genetic condition may cause red blood cells to break down prematurely.
GlibenclamideCinoxacin
Severe
GlibenclamideNorfloxacin
Severe

Drug-Drug Interactions

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GlibenclamideCinoxacin
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Glipol Tablet with Cinoxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Co-administration of Glipol Tablet with Cinoxacin can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your urination and if you notice any changes, let your doctor know. If you experience any of these symptoms - high or low blood sugar, severe infections, headaches, dizziness, confusion, or feeling shaky, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
GlibenclamideNorfloxacin
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Norfloxacin with Glipol Tablet may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glipol Tablet can be taken with Norfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
GlibenclamideGrepafloxacin
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Glipol Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Co-administration of Glipol Tablet with Grepafloxacin can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience any of these symptoms - severe infections, headaches, dizziness, drowsiness, confusion, trembling, nausea, hunger, weakness, fast heartbeat, or excessive thirst - it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.
GlibenclamideNalidixic acid
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Nalidixic acid can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glipol Tablet can be taken with Nalidixic acid if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
GlibenclamideMiconazole
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Miconazole with Glipol Tablet may increase the blood levels and effects of Glipol Tablet leading to low blood glucose levels.

How to manage the interaction:
Although there is a possible interaction, Glipol Tablet can be taken with miconazole if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlibenclamideMoxifloxacin
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Moxifloxacin may affect blood glucose levels. Both high blood glucose and low blood glucose.

How to manage the interaction:
Although there is a possible interaction, Glipol Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, rapid heartbeat, increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
GlibenclamideSparfloxacin
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Sparfloxacin can sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glipol Tablet can be taken with sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
GlibenclamideFluconazole
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Glipol Tablet with Fluconazole may cause an increase in the blood levels and effects of Glipol Tablet leading to low blood sugar levels.

How to manage the interaction:
Although there is a possible interaction, Glipol Tablet can be taken with Fluconazole if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlibenclamideLevofloxacin
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Levofloxacin with Glipol Tablet may affect blood glucose levels.

How to manage the interaction:
Although there is a possible interaction, Glipol Tablet can be taken with levofloxacin if prescribed by the doctor. Consult the prescriber if you experience nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, pulse, rapid heartbeat, increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlibenclamideLomefloxacin
Severe
How does the drug interact with Glipol Tablet:
Co-administration of Lomefloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glipol Tablet can be taken with lomefloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Glipol Tablet is used to treat type-2 diabetes, a chronic or lifelong condition affecting how the body processes glucose.
Glipol Tablet contains Glibenclamide, which increases the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control.
Yes, Glipol Tablet can cause constipation. Eat a proper well-balanced diet and drink plenty of fluid to avoid it.
Yes, Glipol Tablet is known to cause an upset stomach if taken empty stomach. So, it should be preferably taken with a meal or just after a meal to avoid an upset stomach.
No, Glipol Tablet is only prescribed for the treatment for the type 2 diabetes along with a healthy diet and lifestyle. It should not be taken for the treatment of type 1 diabetes.
Hypoglycemia refers to low blood sugar levels. The symptoms of hypoglycemia (low blood sugar) include sweating, feeling shaky or anxious, looking pale, feeling hungry, feeling dizzy, and feeling that your heart is pounding (palpitations). Glipol Tablet can cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with Glipol Tablet. People with diabetes are advised to keep a quick sugar source like glucose tablets, honey or fruit juice.
It is highly recommended to avoid or strictly limit alcohol while taking Glipol Tablet. Alcohol can unpredictably lower your blood sugar levels and increase the risk of severe hypoglycaemia. It can also cause an unpleasant reaction involving flushing, nausea, and a rapid heartbeat. Talk to your doctor for personalised advice.
If you feel symptoms of low blood sugar (shakiness, sweating, dizziness, or confusion), immediately consume 15 grams of fast-acting carbohydrates, such as half a cup of fruit juice, three to four glucose tablets, or hard candy. Check your blood sugar again after 15 minutes. If symptoms persist or worsen, contact emergency medical services or talk to your doctor.
Yes, mild weight gain is a known side effect of medications in this class, as they help your body store glucose more efficiently. Following a balanced diet and regular exercise routine can help manage your weight while taking this medicine. Talk to your doctor or a dietitian for support.
This medication is generally not recommended during pregnancy or breastfeeding, as keeping blood sugar levels stable during these times is crucial, and other treatments like insulin are typically preferred. Talk to your doctor immediately if you are pregnant, planning to become pregnant, or breastfeeding.
Glipol Tablet typically begins to lower blood sugar levels within a few hours of taking your first dose. However, it may take several days or weeks of consistent use, alongside dietary adjustments, to see the full benefits in your overall blood sugar control. Talk to your doctor if you do not see improvement.
No, you should not stop taking Glipol Tablet without consulting your healthcare provider. Normal blood sugar levels mean the medication is working effectively. Stopping it suddenly can cause your blood sugar to rise quickly again, increasing the risk of long-term complications. Talk to your doctor before making any changes.
If you have a scheduled surgery or medical procedure, inform your surgeon and doctor well in advance that you are taking Glipol Tablet. You may need to temporarily stop taking the medication or adjust your dose, especially if you are required to fast before the procedure. Talk to your doctor for specific instructions.
While Glipol Tablet does not typically cause kidney damage, it is processed by the kidneys and liver. If you have pre-existing kidney or liver problems, the medication can accumulate in your body, increasing the risk of severe low blood sugar. Rarely, liver damage can occur. Regular blood tests may be needed, so talk to your doctor about monitoring your kidney and liver health.

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Country of origin

India

Manufacturer/Marketer address

5, Cubit House, 13/369, Panchratna Estate, B/H Ankoor Oil Factory, Opp. Bhagyoday Hotel, Changodar, Ahmedabad-382210 (Guj.) India.
Other Info - GL36609
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