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compositionComposition:GLICLAZIDE-60MG
prescription
Prescription Medicine
info
Glizipol Tablet ER

Glizipol Tablet ER is used to treat type 2 diabetes mellitus when diet and exercise alone cannot control blood sugar levels. It contains Gliclazide, which works by increasing the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. It prevents the blood glucose level from rising, thus keeping your blood sugar level under control. In some cases, you may experience certain common side effects, such a stomach ache or indigestion, nausea, vomiting, and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

GLICLAZIDE-60MG

Manufacturer/Marketer :

Medipol Pharmaceutical India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Glizipol Tablet ER

Glizipol Tablet ER is an oral prescription medication used to help control blood sugar levels in adults with type 2 diabetes. It is prescribed when diet, exercise, and weight loss alone are not enough to keep blood sugar within a healthy range. By keeping your blood sugar under control, this medicine helps prevent long-term damage to your organs.

You will typically take Glizipol Tablet ER once daily, usually with breakfast or your first main meal of the day. To achieve the best results, it is essential to take it consistently at the same time every day. Combining this treatment with a balanced, low-sugar diet and regular physical activity is key to managing your condition effectively.

While taking Glizipol Tablet ER, some people may experience mild side effects like a temporary upset stomach or mild headaches. However, you must contact your doctor immediately if you experience signs of severe low blood sugar, such as sweating, shaking, or confusion, or signs of liver damage, like yellowing of your eyes or skin.

Do not take this if you have type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver disease. Before starting Glizipol Tablet ER, tell your doctor if you have a history of G6PD deficiency or thyroid disorders so they can determine if this treatment is safe for you.

This medicine can interact with several other drugs, including certain painkillers and antifungal treatments, which can increase the risk of low blood sugar. Avoid drinking alcohol while taking this medicine, as it can cause sudden and dangerous drops in your blood sugar. If you are pregnant, planning to become pregnant, breastfeeding, or over 65 years old, talk to your doctor or pharmacist before using this medicine.

Uses of Glizipol Tablet ER

Glizipol Tablet ER is used to treat Type 2 diabetes mellitus. The detailed uses of Glizipol Tablet ER are as follows:

  • Type 2 diabetes mellitus: It is used alongside healthy eating and regular exercise to lower high blood sugar levels in adults whose diabetes cannot be controlled by lifestyle changes alone.

Key Benefits

Glizipol Tablet ER helps lower and maintain healthy blood sugar levels in people with diabetes. By improving blood sugar control, it supports overall health and helps reduce the risk of complications associated with long-term elevated glucose levels. This medicine offers several key benefits:

  • Helps Maintain Healthy Blood Sugar Levels: Glizipol Tablet ER works to improve blood sugar control throughout the day, helping to keep glucose levels within the target range. Consistent blood sugar management is an important part of effective diabetes care.
  • Supports Protection Against Diabetes-Related Complications: By helping control blood sugar levels over the long term, Glizipol Tablet ER may reduce the risk of complications that can affect the nerves, kidneys, eyes, and other organs. Maintaining stable glucose levels is essential for preserving overall health and well-being.
  • Promotes Better Long-Term Cardiovascular Health: Good blood sugar control can contribute to a lower risk of cardiovascular complications associated with diabetes. By supporting overall metabolic health, Glizipol Tablet ER helps individuals maintain an active lifestyle and improve their long-term quality of life.

Directions for Use

Take this medicine exactly as your doctor has directed. Follow these steps for safe use:

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, especially if your doctor has prescribed a modified-release version.
  • Always take your dose with breakfast or your first main meal of the day to prevent your blood sugar from dropping too low.
  • Never skip a meal after taking this medicine.
  • Remember to follow your doctor's exact instructions regarding your daily schedule.

How Glizipol Tablet ER Works

Glizipol Tablet ER belongs to a group of medicines that stimulate the pancreas. It works by prompting the insulin-producing cells in your pancreas to release more insulin, which is the natural hormone responsible for clearing sugar from your blood. By increasing the amount of insulin your body produces after meals, Glizipol Tablet ER helps move sugar from your bloodstream into your cells, where it can be used for energy. This action helps prevent the sharp spikes in blood sugar that typically occur after eating.
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Alcohol

Unsafe

Do not consume alcohol while taking Glizipol Tablet ER. Taking Glizipol Tablet ER with alcohol can cause hypoglycemia.

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Pregnancy

Unsafe

Glizipol Tablet ER is not recommended during pregnancy. Consult the doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Glizipol Tablet ER is not recommended during lactation. Consult the doctor if you are breastfeeding.

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Driving

Caution

Glizipol Tablet ER may cause hypoglycemia (low blood sugar levels). This may affect your ability to drive. Use caution while driving or doing anything that requires concentration or mental alertness.

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Liver

Caution

Glizipol Tablet ER may not be recommended for patients with severe liver disease. Consult the doctor if you have a history of liver diseases/conditions.

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Kidney

Caution

Glizipol Tablet ER may not be recommended for patients with severe kidney disease. Consult the doctor if you have a history of kidney diseases/conditions.

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Children

Unsafe

Glizipol Tablet ER is not recommended for children as the safety and effectiveness of have not been established.

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Heart

Consult your doctor

Please consult your doctor before using Glizipol Tablet ER if you have pre-existing heart problems. Your doctor will prescribe Glizipol Tablet ER if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Glizipol Tablet ER to geriatric patients. Your doctor will prescribe Glizipol Tablet ER if the benefits outweigh the risks.

What if I have taken an overdose of Glizipol Tablet ER

Do not take more than the prescribed dose of Glizipol Tablet ER as it may cause overdose. The signs of overdose include low blood sugar. The symptoms of low blood sugar can be reduced by taking sugar (4 to 6 lumps) or sugary drinks immediately, follwed by a substantial meal or snack. If the patient is unconscious, please seek medical help immediately.

Diet & Lifestyle Advise

  • Eat consistent meals: Do not skip meals, especially breakfast, as this medicine increases insulin production and skipping meals can trigger low blood sugar.
  • Carry fast-acting sugar: Always keep glucose tablets, fruit juice, or hard sweets with you to treat sudden drops in blood sugar.
  • Track your carbohydrates: Work with a dietitian to learn how to monitor your daily carbohydrate intake, which directly affects your blood sugar levels.
  • Exercise regularly: Aim for regular physical activity, but monitor your blood sugar before and after exercise, as physical exertion can lower your blood sugar.

Have a query?

How Soon It Starts Working

The time required for Glizipol Tablet ER to start to work: Glizipol Tablet ER ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Glizipol Tablet ER last: The effect of Glizipol Tablet ER lasts for 1 to 2 days.

What if you forget to take Glizipol Tablet ER

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store Glizipol Tablet ER tablets in their original packaging to protect them from moisture and light. Keep the medicine at room temperature, below 30°C. •Do not store them in the bathroom or near a sink.

Drug Warnings

  • Always check your blood sugar levels regularly as advised by your doctor, especially during times of stress, illness, or travel.
  • Carry a form of medical identification, such as a card or bracelet, that states you have diabetes and are taking Glizipol Tablet ER.
  • Be cautious when driving or operating machinery until you know how this medicine affects you, as low blood sugar can impair your concentration and reaction times.
  • Tell any healthcare professional treating you, including dentists and surgeons, that you are taking this medicine.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Other diabetes medications: Combining this medicine with insulin or other oral diabetes drugs may increase the risk of extremely low blood sugar.
  • Painkillers (NSAIDs): Certain pain-relieving medicines, like ibuprofen, can raise the active levels of this medicine in your blood, increasing the risk of low blood sugar.
  • Antifungal medicines: Drugs like fluconazole can slow down how your body processes this medicine, which may lead to severe low blood sugar.
  • Beta-blockers: These blood pressure medicines can mask the warning signs of low blood sugar, such as a rapid heart rate.

Drug-Food Interactions

  • Alcohol: Drinking alcohol while taking this medicine can interfere with your liver's ability to release sugar, raising the risk of severe and unpredictable low blood sugar.

Drug-Disease Interactions

  • Kidney or liver disease: Impaired kidney or liver function can cause the medicine to build up in your body, significantly increasing the risk of severe low blood sugar.
  • G6PD deficiency: People with this genetic condition may develop a serious blood disorder (haemolytic anaemia) when taking this class of medicine.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Glizipol Tablet ER is used to treat type 2 diabetes mellitus when diet and exercise alone cannot control blood sugar levels.
Glizipol Tablet ER works by increasing the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels.
In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed. In type 2 diabetes, though islet cells are working, the body does not respond to insulin as it becomes resistant to insulin.
Yes, Glizipol Tablet ER can cause indigestion. Eat a proper well-balanced diet and drink plenty of fluid to avoid it.
In some cases, hypoglycemia or low blood sugar may occur. If you feel your blood sugar level is going down and feel weak, immediately eat sugar candies. It helps balance the blood sugar level in your body.
No. Glizipol Tablet ER is only prescribed for the treatment of type 2 diabetes also called as 'non-insulin-dependent diabetes'.
The common side effects of Glizipol Tablet ER are stomach ache or indigestion, feeling sick (nausea), vomiting, and constipation. Most of these side effects do not require medical attention and resolve gradually over time. However, please consult your doctor if you experience these side effects persistently.
The best time to take Glizipol Tablet ER is before breakfast, or typically 30 minutes before the day's first meal. Taking Glizipol Tablet ER at this time helps control blood sugar levels throughout the day. However, following your doctor's or pharmacist's specific instructions for taking your medication is essential.
No, Glizipol Tablet ER and metformin are not the same. They are both used to manage type 2 diabetes, but they work in different ways. Glizipol Tablet ER belongs to a class of sulfonylureas, whereas metformin belongs to a class of biguanides. Both are effective, but they are prescribed to the patient's needs and conditions based on their mechanism.
Glizipol Tablet ER can be taken together with metformin. Your doctor may recommend combining these medications based on your individual condition and needs to improve blood sugar control and reduce complication risks. Do not take them together unless your doctor advises you to do so.
Glizipol Tablet ER is not recommended for use in patients with severe kidney impairment. Please consult your doctor if you have any concerns before using Glizipol Tablet ER.
No, you should avoid drinking alcohol while taking this medicine. Alcohol increases the risk of experiencing dangerous drops in blood sugar and can mask the warning signs of hypoglycemia. Talk to your doctor or pharmacist if you have concerns about this.
You should not take this medicine during pregnancy. Insulin is usually preferred to manage blood sugar during pregnancy to ensure the safety of the developing baby. If you are planning a pregnancy or become pregnant, talk to your doctor or pharmacist immediately.
This medicine starts working within a few hours of taking your first dose to help stimulate insulin release. However, it may take a few weeks of consistent use, alongside diet and lifestyle changes, to see a stable improvement in your overall blood sugar patterns. Talk to your doctor if your blood sugar remains high.
Yes, some people may experience mild weight gain when starting this medicine. This is because your body begins to process and store sugar more efficiently instead of losing it through your urine. Managing your calorie intake and staying active can help control your weight. Talk to your doctor or pharmacist for guidance.
You must inform your surgeon or anaesthesiologist that you are taking Glizipol Tablet ER well in advance. You may need to temporarily stop taking this medicine before your surgery to avoid low blood sugar while fasting. Talk to your doctor for specific instructions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Health Service (NHS). Gliclazide - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Gliclazide 40Mgs Leaflet Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. National Health Services National Health Services. 2022. [Accessed on 28 June 2023] Check here
  5. Ema.Ziclaseg 30mg Prolonged Release Tablet. [[Accessed on 7.Aug].2019] Check here
  6. Les Laboratoires Servier. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 17th January 2024] Check here
  7. Accord. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 17th January 2024]Check here

Country of origin

India
Other Info - GL78729
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