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  3. Glubreak M 50/500 Tablet 10's

Glubreak M 50/500 Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Glubreak M 50/500 Tablet 10's is used for the management and treatment of type 2 diabetes, especially in people whose sugar levels are too high and cannot be controlled by diet and exercise alone. It contains Metformin and Acarbose, which works by reducing the amount of blood sugar released in the bloodstream by the liver, thereby making the body respond in a better way to insulin. Also, it slows down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose. Thereby, slows down and reduces the absorption of sugar into the blood after every meal. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ACARBOSE-50MG + METFORMIN-500MG

Manufacturer/Marketer :

N Line Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Glubreak M 50/500 Tablet 10's

Glubreak M 50/500 Tablet 10's is primarily used for the management and treatment of type 2 diabetes, especially in people whose sugar levels are too high and cannot be controlled by dieting and exercising alone. Type 2 diabetes is a condition which occurs when there is either less insulin or available insulin is not properly utilized by our body cells for lowering raised blood glucose. It is the most common type of diabetes, accounting for around 90% of total diabetes cases found commonly in middle-aged people. So it is also called adult-onset diabetes or non-insulin-dependent diabetes mellitus (NIDDM).

Glubreak M 50/500 Tablet 10's contains two medicines namely: 'Metformin' and 'Acarbose'. Metformin is a 'biguanides' that works by reducing the amount of blood sugar released in the bloodstream by the liver, thereby making the body respond in a better way to insulin. On the other hand, 'Acarbose; is an ‘alpha glucosidase inhibitor’ which works by slowing down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose thereby slowing and reducing the absorption of sugar into the blood after every meal.

Take Glubreak M 50/500 Tablet 10's as prescribed. Your doctor will recommend how often you need to take Glubreak M 50/500 Tablet 10's based on your medical condition. Some people may experience some unpleasant effects at the beginning of the treatment with Glubreak M 50/500 Tablet 10's such as increased wind, rumbling in the stomach and abdominal cramps, which happen as the body adjusts to the new medicine. However, if these unpleasant effects continue for more than days or become severe or you experience diarrhoea, then seek medical attention immediately.

If you are hypersensitive to any of the components present in these medicines, then please tell your doctor before taking this drug. Glubreak M 50/500 Tablet 10's is not recommended for use in children. If you are pregnant, breastfeeding, or planning to be pregnant, then tell your doctor before they prescribe this medicine to you. Limit your alcohol consumption with Glubreak M 50/500 Tablet 10's, as alcohol may cause a rapid increase or decrease in blood sugar levels.

Uses of Glubreak M 50/500 Tablet 10's

Treatment of Type 2 diabetes mellitus.

Directions for Use

• Glubreak M 50/500 Tablet 10's should be taken with meals to prevent stomach upset.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Glubreak M 50/500 Tablet 10's as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Glubreak M 50/500 Tablet 10's is an anti-diabetic drug indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). This medicine is primarily prescribed to persons whose blood sugar levels are high and are not even controlled by diet and exercise alone. Glubreak M 50/500 Tablet 10's consists of Acarbose and Metformin, used for controlling raised blood sugar in type 2 diabetes patients. Acarbose is an ‘alpha-glucosidase inhibitor’ responsible for the inhibition of intestinal enzymes that delay the digestion of carbohydrates taken through the meal. Metformin belongs to a group of medications called 'biguanides' that works by improving glucose tolerance in patients dealing with type 2 diabetes. It also reduces the intestinal absorption of glucose and thus increases the utilization of glucose. Together, they avoid the additional risk of disease associated with diabetes, such as eye problems (diabetes retinopathy), kidney damage (diabetic nephropathy), nerve damage (diabetic neuropathy), diabetic foot ulcers, delayed wound healing and other diabetic complications.

How Glubreak M 50/500 Tablet 10's Works

Glubreak M 50/500 Tablet 10's contains two medicines namely: 'Metformin' and 'Acarbose'. Metformin is a 'biguanides' that works by reducing the amount of blood sugar released in the bloodstream by the liver, thereby making the body respond in a better way to insulin. On the other hand, 'Acarbose; is an ‘alpha glucosidase inhibitor’ which works by slowing down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose thereby slowing and reducing the absorption of sugar into the blood after every meal.

Storage

Keep Glubreak M 50/500 Tablet 10's out of the sight and reach of children.

What if I have taken an overdose of Glubreak M 50/500 Tablet 10's

Do not take more than the prescribed dose of Glubreak M 50/500 Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Tell your doctor if you have kidney disease, high ketone levels in blood or urine,  heart disease, congestive heart failure, liver disease or you are using insulin, or other oral diabetes medications. A person should keep taking Glubreak M 50/500 Tablet 10's even if they are feeling that their blood sugar levels are under control as it may again spike the level of sugar in the blood. Try to take a dose at the right time so that you did not forget to take a dose, ask your doctor for advice. It may be possible that a person may develop lactic acidosis, which happens due to the overproduction of lactic acid in the blood so tell your doctor if you are noticing any symptoms of it. You should take small frequent meals and don't fast while being treated with Glubreak M 50/500 Tablet 10's. Try to notice if you are developing the symptoms of hypoglycemia (low blood sugar) like sweating, dizziness,  dry mouth, dry skin, palpitations, shivering, intense thirst, frequent urination, etc. If you notice any of the mentioned symptoms, then immediately take 5-6 candies or honey/sugar and consult with a physician. 
 

Drug-Drug Interactions

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AcarboseGatifloxacin
Critical
MetforminMetrizamide
Critical

Drug-Drug Interactions

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AcarboseGatifloxacin
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Glubreak M 50/500 Tablet with Gatifloxacin may cause high or low blood sugar in diabetic patients.

How to manage the interaction:
Although there is a possible interaction between Glubreak M 50/500 Tablet and Gatifloxacin, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as sweating, shaking, nervousness, palpitations, or excessive hunger, please contact a doctor. Do not discontinue the medication without consulting a doctor.
MetforminMetrizamide
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Glubreak M 50/500 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Glubreak M 50/500 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Glubreak M 50/500 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Glubreak M 50/500 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Iopamidol with Glubreak M 50/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glubreak M 50/500 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopromide
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Iopromide with Glubreak M 50/500 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Glubreak M 50/500 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIomeprol
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Iomeprol with Glubreak M 50/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glubreak M 50/500 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Ioversol with Glubreak M 50/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glubreak M 50/500 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Iopentol with Glubreak M 50/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glubreak M 50/500 Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Iohexol with Glubreak M 50/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glubreak M 50/500 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Glubreak M 50/500 Tablet:
Co-administration of Iopanoic acid with Glubreak M 50/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glubreak M 50/500 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should engage themself in regular exercise like cycling, running, walking, jogging, dancing, or swimming for at least 30 minutes. Try to invest at least 150 minutes weekly in exercise.

  • A person should also maintain healthy body weight to avoid obesity or high blood sugar it can increase the risk of the onset of diabetes.

  • A person should take low fat and a low sugar diet. For that replace carbohydrates with whole grains, fruits, and vegetables as carbohydrates changed into sugars leading to high blood sugar levels.

  • Try to avoid potatoes as they are high glycemic foods that increase the risk of high sugar in the blood.

  • A person should limit the consumption of alcohol and quit smoking.

 

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Glubreak M 50/500 Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are should avoid consuming alcohol with Glubreak M 50/500 Tablet 10's as it may lead to high or low blood sugar levels.

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Pregnancy

Caution

Glubreak M 50/500 Tablet 10's is a Category B pregnancy drug that is not recommended for pregnant women or given only when strictly guidance of the doctor as there is no clinical data available on use in pregnant women.

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Breast Feeding

Caution

Avoid nursing your baby while taking Glubreak M 50/500 Tablet 10's as this medicine may pass in breast milk.

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Driving

Safe if prescribed

Glubreak M 50/500 Tablet 10's is safe to take before driving as it does not affect your thinking ability.

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Liver

Caution

Take Glubreak M 50/500 Tablet 10's only after the doctor's prescription, especially if you are dealing with Liver diseases/conditions as your doctor may adjust the dose as required.

bannner image

Kidney

Caution

Take Glubreak M 50/500 Tablet 10's after the recommendation of a doctor, especially if you have a history of Kidney diseases/conditions. The dosing strength needs to be adjusted by your doctor as required.

bannner image

Children

Unsafe

The use of Glubreak M 50/500 Tablet 10's is unsafe for children below 12 years.

Have a query?

FAQs

Glubreak M 50/500 Tablet 10's is used for the management and treatment of type 2 diabetes. It works by reducing the amount of blood sugar released in the bloodstream by the liver and slowing down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose.

The use of Glubreak M 50/500 Tablet 10's is strictly prohibited in persons already taking 'digoxin' for treating heartbeats as it may lead to serious drug interaction. One should tell their doctor. If a person needs to take both medicines together, then they need to consult with their doctor so that their doctor may adjust the dose appropriately to use safely.

Glubreak M 50/500 Tablet 10's is contraindicated in the condition of 'diabetic ketoacidosis' or 'lactic acidosis' as it may lead to overload of acids or ketones in your blood and kidney is unable to remove it leading to sever life threatening conditions.

You should try to take small meals at regular intervals and should not skip your meals as it can help Glubreak M 50/500 Tablet 10's to work more effectively by utilizing glucose in the right manner. Fasting is dangerous for diabetes patient taking Glubreak M 50/500 Tablet 10's as it would lower blood sugar level leading to hypoglycemia.

No, a person should continue taking Glubreak M 50/500 Tablet 10's as much doctor has prescribed for the treatment of type 2 diabetes. You should not stop discontinuing Glubreak M 50/500 Tablet 10's suddenly as it may worsen the symptoms of type 2 diabetes and increase the blood sugar level leading to hyperglycemia.

Country of origin

India

Manufacturer/Marketer address

N Line Healthcare
Other Info - GLU1166

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:38 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.9999.pdf
  2. https://www.drugs.com/food-interactions/acarbose.html

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