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compositionComposition:ACARBOSE-25MG
prescription
Prescription Medicine
info
Glucobay 25 Tablet 10's
Glucobay 25 Tablet 10's
Glucobay 25 Tablet 10's
Glucobay 25 Tablet 10's
Glucobay 25 Tablet 10's

Glucobay 25 Tablet is used to treat type 2 diabetes. It contains Acarbose, which works by delaying the absorption of sugar into the blood and reducing the abnormal rise in blood sugar levels after meals. In some cases, you may experience side effects such as flatulence (gas), stomach pain, or diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ACARBOSE-25MG

Manufacturer/Marketer :

Bayer Zydus Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Glucobay 25 Tablet

Glucobay 25 Tablet is a prescription oral tablet used to manage blood sugar levels in adults with type 2 diabetes. It works by slowing down the digestion of carbohydrates, which helps prevent sharp spikes in your blood sugar after you eat. Keeping your blood sugar in a safe range is essential to lowering the risk of long-term diabetes complications like kidney damage or nerve problems.

To get the best results, you must take this medication consistently with your main meals, usually three times a day. You should take each tablet with the very first bite of your meal to ensure it works correctly in your digestive tract. Combining this medicine with a balanced diet and regular physical activity will significantly improve your overall blood sugar control.

The most common side effects of Glucobay 25 Tablet involve the digestive system, such as gas, stomach rumbling, and mild diarrhoea, which often improve as your body adjusts. However, if you experience persistent severe abdominal pain, worsening diarrhoea, or yellowing of your eyes and skin, you should consult your doctor immediately.

Do not take this if you have inflammatory bowel disease, severe liver disease like cirrhosis, blockages in your intestines, or chronic digestive disorders that affect how you absorb food. It is also not suitable for people with large hernias or conditions that might worsen due to increased intestinal gas. Always discuss your complete medical history with your healthcare provider before starting treatment.

This medication can interact with other drugs, including digestive enzymes, certain heart medications, and other diabetes medicines, which may increase your risk of low blood sugar. Avoid heavy alcohol use as it can affect your blood sugar levels, and consult your doctor if you are pregnant, breastfeeding, or managing other chronic health conditions at an older age.

Uses of Glucobay 25 Tablet

Glucobay 25 Tablet is used to help manage blood sugar levels in adults with type 2 diabetes. The detailed uses of Glucobay 25 Tablet are as follows: 

  • Type 2 diabetes mellitus: Glucobay 25 Tablet helps lower high blood sugar levels after meals by delaying the breakdown of complex sugars and starches in your gut.
  • Post-meal blood sugar management: It specifically targets and reduces post-meal glucose spikes, helping to maintain stable blood sugar readings throughout the day when used alongside diet and exercise.

Key Benefits

Glucobay 25 Tablet helps manage blood sugar levels by slowing the digestion and absorption of carbohydrates in the intestine. This leads to a more gradual rise in blood sugar after meals and provides several long-term benefits:

  • Reduces Post-Meal Blood Sugar Spikes: Helps slow the digestion of starches and sugars, promoting a smoother and more predictable increase in blood sugar levels after eating.
  • Supports Steady Energy Levels: By reducing sudden blood sugar fluctuations, it may help minimise energy crashes, fatigue, and difficulty concentrating that can occur after high blood sugar spikes.
  • Protects Long-Term Health: Maintaining more stable blood sugar levels over time may help reduce the risk of diabetes-related complications affecting the kidneys, eyes, heart, and blood vessels.
  • Lower Risk of Low Blood Sugar: When used on its own, Glucobay 25 Tablet has a lower risk of causing sudden low blood sugar because it works in the digestive tract rather than stimulating the pancreas to release more insulin.
Side effects of Glucobay 25 Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Directions for Use

To get the full benefit of Glucobay 25 Tablet , follow these step-by-step instructions carefully:

  • Take the tablet orally with the very first bite of your main meal.
  • Swallow the tablet whole with a sip of water, or chew it with your first mouthful of food as directed by your healthcare provider.
  • Do not take the tablet on an empty stomach or between meals, as it will not be effective.
  • If you find it difficult to swallow, talk to your pharmacist about alternative ways to take your medication safely.

Always follow your doctor's exact instructions regarding how many tablets to take. Your doctor may start you on a lower dose and gradually increase your dose to help minimise stomach-related side effects.

How Glucobay 25 Tablet Works

Glucobay 25 Tablet contains acarbose, which works directly in your small intestine to change how your body processes carbohydrates. When you eat foods like bread, rice, or potatoes, your digestive system uses special enzymes to break down these complex starches into simple sugars that your body can absorb into the bloodstream. This medicine temporarily blocks these digestive enzymes, specifically alpha-glucosidase. By interfering with these enzymes, Glucobay 25 Tablet delays the digestion and absorption of carbohydrates. As a result, sugar enters your bloodstream much more slowly and gradually, which keeps your blood sugar levels from surging after your meal.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Glucobay 25 Tablet as it may cause high or low blood sugar levels.

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Pregnancy

Unsafe

Glucobay 25 Tablet is a Category B pregnancy drug and is generally not recommended for pregnant women, as there is no clinical data available on use in pregnant women.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Glucobay 25 Tablet as it may be excreted in breast milk.

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Driving

Safe if prescribed

Glucobay 25 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Glucobay 25 Tablet with caution, especially if you have a history of liver problems like cirrhosis, as it may worsen your condition. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Patients with diabetes who also have end-stage renal disease (ESRD) or chronic kidney disease (CKD) should not use Glucobay 25 Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

It is not recommended for children.

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Heart

Safe if prescribed

Glucobay 25 Tablet is generally safe and beneficial for many heart patients. However, it must be used under a doctor's supervision.

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Geriatrics

Safe if prescribed

Glucobay 25 Tablet is safe for use in geriatric patients if taken under medical supervision.

What if I have taken an overdose of Glucobay 25 Tablet

Take Glucobay 25 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause serious side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Treat lows with pure glucose: If you experience low blood sugar while taking Glucobay 25 Tablet alongside other diabetes medications, you must treat it with pure glucose (such as dextrose tablets or gels) rather than regular sugar. Because this medicine blocks the breakdown of table sugar, regular sweets, soda, or juice will not raise your blood sugar quickly enough in an emergency.
  • Manage carbohydrate portion sizes: Eat consistent, moderate portions of complex carbohydrates (like whole grains and vegetables) across your meals to help the medicine work steadily and minimise gas.
  • Monitor your blood sugar: Keep a regular log of your pre-meal and post-meal blood sugar levels as directed by your healthcare team to track how well your treatment plan is working.
  • Stay active: Engage in regular, moderate exercise like walking after meals to help your muscles burn glucose more efficiently, which works hand-in-hand with your medication.

Have a query?

How Soon It Starts Working

  • The time required for Glucobay 25 Tablet to start to work: The time required for Glucobay 25 Tablet to show its action is unknown.
  • The time for which the effects of Glucobay 25 Tablet last: The duration of action for Glucobay 25 Tablet is unknown.

What if you forget to take Glucobay 25 Tablet

If you miss a dose, don’t take it between meals. Just wait for your next scheduled dose with a meal. Do not take a double dose.

Storage

•Store Glucobay 25 Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Keep glucose tablets on hand: Always carry glucose gel or dextrose tablets with you. Regular table sugar, candy, or soda will not treat low blood sugar effectively while you are taking this medication.
  • Avoid digestive aids: Do not take over-the-counter enzyme supplements (like amylase or pancreatin) or charcoal tablets, as they can stop Glucobay 25 Tablet from working properly in your gut.
  • Watch for liver health: Your doctor may perform routine blood tests to check your liver function while you are taking this medicine, especially during the first year of treatment. Keep all scheduled laboratory appointments.
  • Watch your diet to reduce gas: Excessive intake of sugar or starches can worsen flatulence and bloating. Sticking to your recommended meal plan is the best way to keep these digestive side effects manageable.
  • Inform all healthcare providers: Let your dentist, surgeon, and any other doctors know that you are taking Glucobay 25 Tablet before undergoing any procedures or starting new treatments.

Drug-Drug Interactions

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Drug-Drug Interactions

Glucobay 25 Tablet is used to help manage blood sugar levels in adults with type 2 diabetes. The detailed uses of Glucobay 25 Tablet are as follows: 

  • Digestive enzymes and adsorbents: Medications containing digestive enzymes (such as amylase or pancreatin) and activated charcoal can significantly reduce the effectiveness of Glucobay 25 Tablet .
  • Sulfonylureas and insulin: Combining Glucobay 25 Tablet with these medications increases your risk of developing low blood sugar (hypoglycemia).
  • Digoxin: This medicine may reduce the absorption of digoxin, potentially lowering its effectiveness in managing heart conditions.
  • Thiazide diuretics and thyroid products: These medicines can raise blood sugar levels, which may require your doctor to adjust your diabetes treatment plan.

Drug-Food Interactions

Certain foods and beverages may affect how Glucobay 25 Tablet works or increase the risk of side effects. Examples include: 

  • Household sugar (sucrose): Consuming table sugar, cane sugar, or sweetened foods while experiencing low blood sugar will not work because Glucobay 25 Tablet delays the absorption of sucrose. Use pure dextrose or glucose instead.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Glucobay 25 Tablet , as it may worsen your condition or require additional monitoring: 

  • Inflammatory bowel disease (IBD) and intestinal blockages: Do not take this medicine if you have chronic bowel inflammation, ulcers, or a history of intestinal blockages, as increased gas production can worsen these conditions.
  • Severe kidney or liver damage: People with severe kidney impairment or liver diseases like cirrhosis should avoid this medication, as it has not been fully studied or may cause further complications in these groups.
AcarboseGatifloxacin
Critical
AcarboseMipomersen
Severe

Drug-Drug Interactions

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AcarboseGatifloxacin
Critical
How does the drug interact with Glucobay 25 Tablet:
Co-administration of Glucobay 25 Tablet with Gatifloxacin may cause high or low blood sugar in diabetic patients.

How to manage the interaction:
Although there is a possible interaction between Glucobay 25 Tablet and Gatifloxacin, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as sweating, shaking, nervousness, palpitations, or excessive hunger, please contact a doctor. Do not discontinue the medication without consulting a doctor.
AcarboseMipomersen
Severe
How does the drug interact with Glucobay 25 Tablet:
Co-administration of Mipomersen and Glucobay 25 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Glucobay 25 Tablet and Mipomersen together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like fever, joint pain, swelling, skin rash, itching, bleeding, vomiting, stomach pain, or dark urine, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
AcarboseLeflunomide
Severe
How does the drug interact with Glucobay 25 Tablet:
Co-administration of Glucobay 25 Tablet with leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Glucobay 25 Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AcarboseKetoconazole
Severe
How does the drug interact with Glucobay 25 Tablet:
Co-administration of Glucobay 25 Tablet with Ketoconazole may increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Glucobay 25 Tablet and Ketoconazole, you can take these medicines together if prescribed by your doctor. However, if you experience fever, skin rash, itching, decreased hunger, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, contact a doctor. Do not discontinue the medication without consulting a doctor.
AcarboseLomitapide
Severe
How does the drug interact with Glucobay 25 Tablet:
Co-administration of Glucobay 25 Tablet with Lomitapide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Glucobay 25 Tablet and Lomitapide you can take these medicines if prescribed by a doctor. However, if you have a fever, joint pain or swelling, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

Glucobay 25 Tablet is used to treat type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.
No, you are not recommended to take Glucobay 25 Tablet with digoxin (used to treat heart problems) as co-administration of these two medicines may decrease the effectiveness of digoxin by reducing its amount in the blood. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately and used safely.
Glucobay 25 Tablet works by inhibiting the action of intestinal enzymes that break down complex sugars and starches into simple sugars. This delays the absorption of sugar into the blood and reduces the abnormal rise in blood sugar levels after meals.
Yes, Glucobay 25 Tablet may cause diarrhoea as a common side effect. Intake of household sugar (cane sugar) or foods containing it can also lead to diarrhoea or severe discomfort in the stomach. However, if the condition worsens or persists for more than 2 or 3 days, please consult your doctor.
No, Glucobay 25 Tablet alone does not cause low blood sugar. However, low blood sugar may occur if Glucobay 25 Tablet is taken along with other antidiabetic medicines, alcohol intake, exercise more than usual, delay or miss snacks or meals. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
You are not advised to take more than the recommended dose of Glucobay 25 Tablet as it may cause Glucobay 25 Tablet overdose, resulting in increased flatulence (gas), stomach discomfort, and diarrhoea. In case of overdose, avoid intake of drinks and foods containing carbohydrates for the next 4 to 6 hours. However, if the symptoms persist or worsen, please consult a doctor.
No, you are not recommended to stop taking Glucobay 25 Tablet on your own, as discontinuing Glucobay 25 Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glucobay 25 Tablet , please consult your doctor so that an alternate medicine may be prescribed.
The side effects of Glucobay 25 Tablet include stomach pain, diarrhoea and flatulence (gas). If these side effects persist or worsen, please consult your doctor.
Glucobay 25 Tablet should be taken with meals either chewed with the first bite of food or swallowed whole with water. Use as advised by the doctor.
If you forget to take a dose of Glucobay 25 Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
Patients who are allergic to Glucobay 25 Tablet , have inflammation or ulceration of the intestine (eg Crohn’s disease), severe liver disease, or intestinal obstruction (cramping pain, vomiting, severe constipation, and lack of flatus), large hernia or an intestinal disease where food is not digested or absorbed properly should avoid taking Glucobay 25 Tablet . Also, pregnant or breastfeeding women should avoid taking Glucobay 25 Tablet .
No, taking Glucobay 25 Tablet on an empty stomach is not effective. This medicine must be taken with the first bite of a main meal so it can interact with the digestive enzymes and food in your intestine. If you skip a meal, you should skip the dose. Talk to your doctor or pharmacist for more personalised advice.
If you experience low blood sugar (hypoglycemia) while taking Glucobay 25 Tablet alongside other diabetes drugs, you must treat it immediately with pure glucose, such as dextrose tablets or glucose gel. Regular sugar, soda, or candy will not work quickly enough because Glucobay 25 Tablet blocks their breakdown. Talk to your doctor if you experience frequent low blood sugar episodes.
Glucobay 25 Tablet slows down the digestion of carbohydrates, which means some undigested starches reach your large intestine. The natural bacteria in your colon ferment these starches, producing gas, bloating, and stomach rumbling. These symptoms are usually mild and improve over time as your body adjusts. Talk to your doctor if these symptoms become severe.
It is best to limit or avoid alcohol while taking Glucobay 25 Tablet . Alcohol can affect your liver function and make your blood sugar levels more unpredictable, increasing your risk of experiencing low blood sugar. Talk to your doctor about what is safe for you.
Glucobay 25 Tablet begins working with your very first dose to slow down carbohydrate digestion during that meal. However, it may take several weeks of consistent use, alongside diet and exercise, to see a significant improvement in your overall blood sugar levels. Talk to your doctor to monitor your progress.
There is limited clinical data on the safety of Glucobay 25 Tablet during pregnancy. Generally, other treatments are preferred to manage diabetes during pregnancy. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor to determine the safest treatment plan.
Yes, Glucobay 25 Tablet is frequently prescribed alongside other diabetes medications like metformin, sulfonylureas, or insulin. However, combining these treatments can increase your risk of low blood sugar, which must be treated specifically with pure glucose. Talk to your doctor before changing your medication regimen.
Glucobay 25 Tablet is not a weight-loss medication, and its primary purpose is to control blood sugar levels. While some patients may notice modest changes in weight due to improved blood sugar management and dietary adjustments, it is not prescribed for weight loss. Talk to your doctor about safe strategies for weight management.

Disclaimer

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.10000 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. U.S. Food and Drug Administration (FDA). 020482S024Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Acarbose Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 18 Feb. 2020] Check here
  5. Acarbose [EMC Label]. 2018. [Accessed on 20 Sep. 2021] Check here
  6. DailyMed DailyMed. [Accessed on 20 Sept. 2021] Check here
  7. Acarbose 50 mg Tablets- Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 2026 Feb 16]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Bayer AG, Müllerstr. 178, 13353 Berlin
Other Info - GLU0003

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