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  3. Gobal 500mcg/100mg Tablet

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Gobal 500mcg/100mg Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Gobal 500mcg/100mg Tablet is used in the treatment of neuropathic pain. It contains Pregabalin and Methylcobalamin, which decreases the pain signals and helps rejuvenate and protect damaged nerve cells. It may cause common side effects such as dizziness, drowsiness, headache, loss of appetite, nausea or vomiting, diarrhea, headache, vision problems, and sweating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

METHYLCOBALAMIN-500MCG + PREGABALIN-100MG

Manufacturer/Marketer :

TNT Lifesciences

Consume Type :

ORAL

Return Policy :

Not Returnable

About Gobal 500mcg/100mg Tablet

Gobal 500mcg/100mg Tablet belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Gobal 500mcg/100mg Tablet is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

You should take this medicine as prescribed by your doctor. The common side-effects of Gobal 500mcg/100mg Tablet are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side effects persist.

Do not take Gobal 500mcg/100mg Tablet if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking Gobal 500mcg/100mg Tablet if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse.  It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as Gobal 500mcg/100mg Tablet may cause dizziness or drowsiness. Gobal 500mcg/100mg Tablet contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor. 

Uses of Gobal 500mcg/100mg Tablet

Gobal 500mcg/100mg Tablet is used in the treatment of Neuropathic pain. The detailed uses of Gobal 500mcg/100mg Tablet are as follows:<br/>•Anxiety Relief: Gobal 500mcg/100mg Tablet known is to help reduce anxiety and tension, fostering a sense of calm and relaxation.<br/>•Pain Management: Gobal 500mcg/100mg Tablet may provide effective relief from various types of pain, including headaches and muscle discomfort.<br/>•Sleep Aid: Gobal 500mcg/100mg Tablet can be beneficial for individuals experiencing sleep disturbances, helping to enhance sleep quality and duration.<br/>•Mood Stabilization: Gobal 500mcg/100mg Tablet may assist in managing mood swings and supporting individuals with depressive symptoms, promoting emotional balance.<br/>•Neuropathic Pain Relief: Gobal 500mcg/100mg Tablet helps reduce nerve pain by calming overactive nerves and supports nerve repair and regeneration.<br/>

Directions for Use

• Take Gobal 500mcg/100mg Tablet with or without food or as advised by a doctor.• Recommended to take the medicine twice a day, in the morning and evening or as advised by your doctor.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Gobal 500mcg/100mg Tablet is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, Gobal 500mcg/100mg Tablet helps in providing relief from neuropathic pain and improved nerve signal conduction.  

 

How Gobal 500mcg/100mg Tablet Works

Gobal 500mcg/100mg Tablet is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

Storage

Keep Gobal 500mcg/100mg Tablet out of the sight and reach of children.

What if I have taken an overdose of Gobal 500mcg/100mg Tablet

Do not take more than the prescribed dose of Gobal 500mcg/100mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Gobal 500mcg/100mg Tablet may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. Gobal 500mcg/100mg Tablet may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with Gobal 500mcg/100mg Tablet may need a change in diabetic medicines. If you notice decreased urination while taking Gobal 500mcg/100mg Tablet, inform your doctor as Gobal 500mcg/100mg Tablet may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing Gobal 500mcg/100mg Tablet. In such cases, inform your doctor immediately.  

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain.

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

 

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT
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Alcohol

Caution

Alcohol may worsen the condition by increasing the risk of side-effects.

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Pregnancy

Unsafe

Gobal 500mcg/100mg Tablet is a category C medicine. It is not recommended for use in pregnant women unless the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Gobal 500mcg/100mg Tablet should be used with caution in breastfeeding mothers unless the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Gobal 500mcg/100mg Tablet may cause dizziness and drowsiness. So, avoid driving or operating heavy machinery while using Gobal 500mcg/100mg Tablet.

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Liver

Caution

Gobal 500mcg/100mg Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Gobal 500mcg/100mg Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary

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Children

Unsafe

Gobal 500mcg/100mg Tablet is not recommended for anyone below the age of 18 years.

Have a query?

FAQs

Gobal 500mcg/100mg Tablet is used in the treatment of neuropathic pain, a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system&amp;#039;s malfunctioning.

Gobal 500mcg/100mg Tablet is a combination of two medicines: Pregabalin and Methylcobalamin. Gobal 500mcg/100mg Tablet block the brain&amp;#039;s pain signals and protect nerve cells from further damage, thereby improving nerve signal conduction to the whole body parts. These effects help to reduce pain in patients with neuropathic pain.

Gobal 500mcg/100mg Tablet should not be given to children and adolescents under the age of 18 years as it may increase suicidal thoughts.

Gobal 500mcg/100mg Tablet should not be stopped abruptly as it may cause withdrawal reactions such as trouble sleeping, headache, nausea, feeling anxious, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. Gobal 500mcg/100mg Tablet should be stopped gradually over a minimum of 1 week.

Gobal 500mcg/100mg Tablet can be used in patients with diabetes if they have neuropathic pain. However, inform your doctor if you notice any weight gain while using Gobal 500mcg/100mg Tablet. Your doctor may change your diabetic medicines to stop weight gain. Also, take some measures to control weight such as eating a balanced diet and exercising regularly.

Gobal 500mcg/100mg Tablet may cause drowsiness. So, it is advised to refrain from activities such as driving or operating heavy machinery if you feel sleepy after taking Gobal 500mcg/100mg Tablet.

You may notice pain improvement within 2-3 days after taking Gobal 500mcg/100mg Tablet. However, it may take 2-3 months for your symptoms to improve depending on your health condition.

Gobal 500mcg/100mg Tablet may increase your appetite, which might make you eat more, and thus increases the risk of weight gain. However, it’s easier to prevent weight gain than losing the weight. Try to eat a healthy balanced diet. Avoid consuming high-calorie foods, such as soft drinks, chips, oily food, biscuits, cakes, and sweets. If you feel hungry between meals, do not eat junk food, instead eat vegetables, fruits, and low-calorie foods. Regular exercise helps to prevent weight gain. If you still have any concerns, discuss with your doctor.

Gobal 500mcg/100mg Tablet may rarely cause serious side effects such as allergic reaction, suicidal thoughts or swelling of limbs (legs, hands, or feet). If you experience any signs of these side effects, discontinue Gobal 500mcg/100mg Tablet and consult your doctor. Signs of an allergic reaction include swelling of your face, lips, mouth, tongue, gums, and neck. Allergic reactions can also lead to skin rash, difficulty breathing, hives (raised bumps) or blisters. Watch out for any changes, especially sudden changes in behaviors, mood, thoughts or feelings, or if you have suicidal thoughts.

Gobal 500mcg/100mg Tablet may show an initial benefit after 2 weeks of taking it. However, for full benefits, it may take around 2 to 3 months or more (in some patients).

If you forget to take a dose of Gobal 500mcg/100mg Tablet, take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.

You are advised to avoid alcohol consumption while taking Gobal 500mcg/100mg Tablet as it may increase the risk of side effects. However, if you have any concerns, please discuss with your doctor.

If you have started taking Gobal 500mcg/100mg Tablet, you may need to see your doctor regularly. However, if the recommended doses does not improve your symptoms or if the side effects persist or worsen which affect your routine activities, consult your doctor.

Store Gobal 500mcg/100mg Tablet at room temperature in a cool place. Protect from light and moisture. Keep it out of reach of children.

The side effects of Gobal 500mcg/100mg Tablet include nausea, vomiting, headache, dizziness, drowsiness, increased appetite, weight gain and vision problems. If these side effects persist or worsen, please consult your doctor.

You are recommended to take Gobal 500mcg/100mg Tablet only if it is advised by your doctor. Therefore, if you are pregnant or planning pregnancy, take your doctor’s advice.

You are recommended to avoid driving or using any tools or machines until you know how Gobal 500mcg/100mg Tablet affects you as it may cause dizziness or drowsiness in some people.

Manufacturer/Marketer address

Address : Plot No-110, Industrial Area, Phase-2, Panchkula New Delhi 134113 India
Other Info - GO45694

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 6:42 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.7011.pdf
  2. https://www.npra.gov.my/images/reg-and-noti/PI/non-poison/Mecobalamin-Template-oral-Website.pdf
  3. https://medlineplus.gov/druginfo/meds/a605045.html
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