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  1. Home
  2. Medicine

  3. GP2-Med Tablet

GP2-Med Tablet, Pack of 1 TABLET
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Composition :

GLIMEPIRIDE-2MG

Manufacturer/Marketer :

3M India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About GP2-Med Tablet

GP2-Med Tablet belongs to a class of antidiabetic called 'sulfonylureas' used to lower raised blood sugar levels in Type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus - NIDDM). Type 2 diabetes develops if the body does not produce enough insulin or when your body's insulin does not work as well as it should. Insulin is a substance that helps to lower the level of sugar in your blood, especially after meals.

The GP2-Med Tablet contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. Therefore, it prevents symptoms of type 2 diabetes.

Take GP2-Med Tablet as prescribed by your doctor. Some people may experience an allergic reaction (skin rash, hives & sensitivity to sun rays), liver dysfunction (jaundice, bile duct blockage, and hepatitis), seizures, coma & low glucose levels. Most of these side effects of GP2-Med Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

GP2-Med Tablet should not be stopped even if you feel better without consulting your doctor as the sugar level keeps changing. If you stop taking GP2-Med Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). GP2-Med Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease or plan to get pregnant or breastfeed.

Uses of GP2-Med Tablet

Treatment of Type 2 diabetes

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

GP2-Med Tablet is used in people with type 2 diabetes to minimize elevated blood sugar levels with a balanced diet and exercise in combination. GP2-Med Tablet can be combined with insulin or other forms of oral antidiabetic medication. GP2-Med Tablet decreases blood sugar levels in a diabetic patient by increasing the production and secretion of insulin from the pancreas beta cells. Thus, it helps in controlling increased blood sugar levels after the meal.

How GP2-Med Tablet Works

The GP2-Med Tablet contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. Therefore, it prevents symptoms of type 2 diabetes.

Storage

Store in a cool and dry place away from sunlight
Side effects of GP2-Med Tablet
  • Apply an ice pack to slow bleeding and reduce swelling.
  • Keep your head raised to help blood drain away from your eye.
  • Take rest and avoid intense activities that raise pressure in the eye.
  • If the bleeding is severe or does not improve within 24 hours, consult a doctor.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.

What if I have taken an overdose of GP2-Med Tablet

Do not take more than the prescribed dose of GP2-Med Tablet as it may cause overdose leading to low blood sugar. Early signs of low blood sugar include sweating, feeling hungry, trembling or shaking, feeling confused, or having problems concentrating. If you suspect you low blood sugar, eat or drink something that quickly increases blood sugar levels such as fruit juice or sugar cubes. However, if your condition does not improve, please consult a doctor immediately.

Drug Warnings

Before taking GP2-Med Tablet, inform your doctor if you are healing from injury, had or going to have surgery, have fever infections or other sources of stress, then contact your doctor as it might be appropriate to adjust care temporarily. If you have a serious kidney/liver disease, breastfeeding or pregnant, consult the doctor before using GP2-Med Tablet. Do not take GP2-Med Tablet if you are allergic to sulpha drugs, glimepiride, or any other antidiabetic medicines or have a deficiency of glucose 6-phosphate dehydrogenase (G6PD). A heart disease patient should consult a doctor before taking the GP2-Med Tablet as it may worsen the heart disease's current conditions. Do not take GP2-Med Tablet with oral contraceptives as it may increase blood sugar levels. On the other hand, taking GP2-Med Tablet with pain killers like aspirin or ibuprofen can lower your blood sugar.

Drug-Drug Interactions

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TirofibanWarfarin
Severe
TirofibanDabigatran etexilate
Severe

Drug-Drug Interactions

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TirofibanWarfarin
Severe
How does the drug interact with GP2-Med Tablet:
Coadministration of warfarin with GP2-Med Tablet can increase the risk of bleeding.

How to manage the interaction:
Although taking GP2-Med Tablet and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
TirofibanDabigatran etexilate
Severe
How does the drug interact with GP2-Med Tablet:
Taking Dabigatran etexilate with GP2-Med Tablet can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with GP2-Med Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
TirofibanEnoxaparin
Severe
How does the drug interact with GP2-Med Tablet:
Combining GP2-Med Tablet with Enoxaparin can increase the risk of bleeding.

How to manage the interaction:
Taking Enoxaparin with GP2-Med Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away back pain, numbness, constipation, bleeding, bruises, dizziness, lightheaded, red or black stools, severe headache, weakness, or vomiting blood. Do not discontinue any medications without consulting a doctor.
TirofibanFondaparinux
Severe
How does the drug interact with GP2-Med Tablet:
Taking GP2-Med Tablet with Fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Fondaparinux and GP2-Med Tablet, it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TirofibanCangrelor
Severe
How does the drug interact with GP2-Med Tablet:
Co-administration of GP2-Med Tablet with Cangrelor can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between GP2-Med Tablet and Cangrelor, you can take these medicines together if prescribed by your doctor. However, consult doctor immediately if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
TirofibanIbrutinib
Severe
How does the drug interact with GP2-Med Tablet:
Co-administration of Ibrutinib with GP2-Med Tablet can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with GP2-Med Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
TirofibanRivaroxaban
Severe
How does the drug interact with GP2-Med Tablet:
Co-administration of GP2-Med Tablet and Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of GP2-Med Tablet and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
TirofibanDasatinib
Severe
How does the drug interact with GP2-Med Tablet:
Using dasatinib together with GP2-Med Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of GP2-Med Tablet with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
TirofibanAspirin
Severe
How does the drug interact with GP2-Med Tablet:
Using aspirin together with GP2-Med Tablet can cause you to bleed more easily.

How to manage the interaction:
Co-administration of Aspirin with GP2-Med Tablet can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, bruising, throwing up, headache, feeling dizzy, weakness, or seeing blood in your urine or stools. Do not stop using any medications without talking to a doctor.
TirofibanHeparin
Severe
How does the drug interact with GP2-Med Tablet:
Taking GP2-Med Tablet with Heparin can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Heparin and GP2-Med Tablet, you can take these medicines together if prescribed by a doctor. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.

  • Maintain healthy body weight as obesity is also related to the onset of diabetes.

  • Maintain a low fat and a low sugar diet. Replace carbohydrates containing foods with whole grains, fruits and vegetables as carbohydrates turn to sugars leading to high blood sugar.

  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS AND ANTIHYPERGLYCEMICS

GP2-Med Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Not recommended to take GP2-Med Tablet with alcohol. Alcohol intake may increase or decrease the blood sugar lowering action of GP2-Med Tablet in an unpredictable way resulting in a harmful event.

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Pregnancy

Caution

GP2-Med Tablet is a pregnancy Category C medicine which means that there are no well-controlled studies that have been done in pregnant women. However, if you are taking GP2-Med Tablet during pregnancy, stop taking it at least 2 weeks before your due date or as prescribed by your doctor.

bannner image

Breast Feeding

Caution

Not recommended to be taken by breastfeeding mothers. GP2-Med Tablet may pass into breast milk and may cause the risk of low blood sugar in the infant. Consult your doctor for further advice.

bannner image

Driving

Caution

Not recommended in patients with fluctuating glucose levels. GP2-Med Tablet can reduce the ability to concentrate or react, if your blood sugar is lowered (hypoglycemia) or raised (hyperglycemia) or if you develop visual problems as a result of such conditions. Thus not recommended as the patient can endanger himself or others (e.g. when driving a car or using machines).

bannner image

Liver

Caution

Not recommended in patients with liver dysfunction. A patient should consult a doctor before taking GP2-Med Tablet as it may cause liver damage.

bannner image

Kidney

Caution

Not recommended in patients with kidney dysfunction. A patient should consult a doctor before taking GP2-Med Tablet as it may cause kidney damage.

bannner image

Children

Unsafe

GP2-Med Tablet is not approved for use by a person less than 18 years old.

Have a query?

FAQs

GP2-Med Tablet is used to lower raised blood sugar levels in Type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus - NIDDM).

The GP2-Med Tablet contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. Therefore, it prevents symptoms of type 2 diabetes.

A patient is advised to take the missed dose as soon as possible or skip to the next dose if it's been too late. A patient should never attempt to take a double dose to compensate for the missed dose as it may prove harmful.

GP2-Med Tablet is not recommended with warfarin as these two drugs are contraindicated with each other and hence may result in any harmful symptom when taken together in heart patients.

Avoid intake of GP2-Med Tablet and consult a doctor if you have an allergy to sulfa drugs, diabetic ketoacidosis, heart disease, liver or kidney disease, an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).

Your blood sugar might get decreased, so regular blood glucose monitoring is required. Signs and symptoms of low blood sugar level are feeling very hungry, dizziness, irritability, confusion, anxiety or shakiness. Try to eat or drink a fast-acting sugar source (like fruit juice, hard candy, crackers, raisins or non-diet soda).

No, GP2-Med Tablet is only prescribed to treat type 2 diabetes and not type 1 diabetes. If you are type 1 diabetic patient consult with a doctor so that insulin forms can be prescribed for the same.

The patient is advised to talk to a doctor before taking contraceptive pills if he/she is already taking GP2-Med Tablet, then the doctor may change the dose of GP2-Med Tablet. This is because oral contraceptive pills change body responds to the sugar.

Take GP2-Med Tablet for as long as it is prescribed by your doctor. Do not discontinue GP2-Med Tablet without consulting your doctor.

The side effects of GP2-Med Tablet include nausea, headache, dizziness, and weight gain. If these side effects persist or worsen, please consult your doctor.

The dosage of GP2-Med Tablet is decided by your doctor. Use it in the dose and duration as prescribed.

GP2-Med Tablet does not cause sleepiness by itself. However, it may cause low blood sugar when used with other anti-diabetic medicine. As a result, you may feel sleepy or have problems in sleeping.

GP2-Med Tablet is not recommended for patients with kidney dysfunction. Therefore, if you have any kidney problem, inform your doctor before taking GP2-Med Tablet.

No, GP2-Med Tablet does not cause memory loss. However, the use of GP2-Med Tablet may result in low blood sugar which could impair concentration and alertness.

If you are allergic to GP2-Med Tablet, have severe liver or kidney disease, G6PD-deficiency (an inherited condition affecting red blood cells), type 1 diabetes mellitus (insulin-dependent diabetes) or are about to undergo surgery, avoid taking GP2-Med Tablet. Additionally, patients who are pregnant or breastfeeding, or planning to conceive should also avoid taking GP2-Med Tablet.

GP2-Med Tablet takes 2 to 3 hours to lower blood sugar levels. Even if you don’t notice a difference, the medicine is still effective. Keep taking GP2-Med Tablet as advised by your doctor and if you have any concerns, please discuss with your doctor.

Overdose of GP2-Med Tablet may cause hypoglycaemia (low blood sugar), lasting from 12 to 72 hours, and may recur after an initial recovery. Symptoms may not appear for up to 24 hours after ingestion. Vomiting, nausea and epigastric pain may occur. In case of overdose, please seek medical help immediately.

No, do not take GP2-Med Tablet on empty stomach as it may cause too low blood sugar levels and the symptoms include anxiety, dizziness, irritability, shaking, confusion and a fast heartbeat. Therefore, you always take GP2-Med Tablet with breakfast or the first meal of the day. It is important that you eat every meal when you are on GP2-Med Tablet.

Yes, GP2-Med Tablet may cause weight gain. It stimulates the pancreas to release insulin. It may stimulate hunger and cause mild weight gain in some people. To maintain a stable weight, patients are advised to eat a healthy balanced diet and exercise regularly. However, if you notice changes in your weight, or if you change your lifestyle, or you are in a stress situation, inform your doctor as this may require dose adjustment.

Yes, GP2-Med Tablet may cause dizziness as a side effect. If you experience this side effect, sit or lie down until the symptoms pass. Also, always carry some sugary food or fruit juice with you in case you experience dizziness while travelling.

It is advisable to avoid high saturated and trans fats foods. Instead, consume fats from nuts and fish. Also, control your intake of carbohydrate as this directly affects your blood sugar.

Yes, GP2-Med Tablet is safe to use in prescribed dose and duration. The patient should follow doctor’s recommendations.

Yes, in addition to other necessary nutrients, proteins must be a part of a diabetic's regular diet. Among all the essential nutrients, proteins are one of the main sources of energy. In addition, proteins, which are the building blocks of the human body, decompose into glucose to produce energy. Proteins metabolize significantly more slowly into glucose than carbohydrates do. As a result, it often takes many hours after consumption for the release of energy. Thus, after following a high-protein diet, the blood sugar levels might spike after a few hours.

No, artificial sweeteners are not good for diabetic people. They are made of chemicals that can cause mild to severe side effects. Thus, it is preferable to limit or avoid their use as much as you can.

Yes, uncontrolled diabetes can cause kidney failure. Diabetes over the time may have impact on the kidneys, resulting in a condition called diabetic nephropathy, which is a major cause of kidney failure in diabetic patients. The best way to prevent kidney damage is managing diabetes, changing one’s diet, regular monitoring of sugar levels, routine blood tests, and taking prescribed medications on time.

There is no cure for diabetes. Medication only helps to control diabetes. However, it is advised to maintain proper diet and exercise along with medication to control blood sugar levels.

You are not recommended to consume alcohol while taking GP2-Med Tablet as it may increase the hypoglycaemic (blood sugar lowering) action of GP2-Med Tablet in an unpredictable way.

GP2-Med Tablet should not be taken by pregnant women as there are no adequate data on use of Glimepiride in pregnant women. In case if the patient plans to become pregnant or if a pregnancy is discovered while on treatment with Glimepiride, the treatment should be switched as soon as possible to insulin therapy. Therefore, please discuss with your doctor before taking GP2-Med Tablet if you are pregnant or planning pregnancy.

Country of origin

India

Manufacturer/Marketer address

3M India Ltd, Concorde Block, Ub City, #24, Vittal Mallya Road, Bangalore, Karnataka - 560001 India.
Other Info - GP20003

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:49 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.6048.pdf
  2. https://www.drugs.com/disease-interactions/glimepiride.html
  3. https://www.nhs.uk/medicines/glimepiride/

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