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compositionComposition:CYPROTERONE-2MG+ETHINYLESTRADIOL-0.04MG
prescription
Prescription Medicine
info
Harmoni Tablet 21's

Harmoni Tablet 21's contains Ethylestradiol and Cyproterone. It is used to treat moderate to severe acne related to androgen sensitivity and/or hirsutism (excess hair growth) in women of reproductive age. It works by blocking the production of androgens (male hormones) in the ovaries, thereby helping reduce acne and hair growth. In some cases, this medication may cause nausea, abdominal pain, headache, weight gain and mood changes. Before starting this medicine, inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CYPROTERONE-2MG+ETHINYLESTRADIOL-0.04MG

Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Harmoni Tablet 21's

Harmoni Tablet 21's is an oral prescription medicine used primarily to treat skin and systemic conditions linked to hormone sensitivity, such as moderate to severe acne and excessive facial or body hair growth (hirsutism) in women. It is typically prescribed when other treatments, such as topical creams or oral antibiotics, have not worked. Because of how it works in the body, it also functions as an oral contraceptive, meaning you should not take other hormonal birth control pills alongside it.

For this medicine to work effectively, you must take it consistently at the same time every day. You can take Harmoni Tablet 21's with or without food, though taking it with food or at bedtime may help if you experience mild nausea. Making simple lifestyle adjustments, such as maintaining a gentle skincare routine and eating a balanced diet, can support your treatment results.

Some women may experience mild side effects, including nausea, stomach ache, breast tenderness, or slight changes in body weight. While these are often temporary, you must contact your doctor immediately if you experience signs of serious conditions, such as severe leg pain, sudden chest pain, or difficulty breathing, which could indicate a blood clot.

Before taking Harmoni Tablet 21's, tell your doctor if you have high blood pressure, diabetes, migraines, or a family history of blood clots. Do not take this medicine if you are pregnant, breastfeeding, or have a history of liver damage, unexplained vaginal bleeding, or blood circulation disorders.

This medication can interact with certain epilepsy drugs, tuberculosis treatments, and herbal remedies, which can make it less effective. Smoking while taking Harmoni Tablet 21's significantly increases your risk of serious cardiovascular side effects, so avoiding tobacco is highly recommended. It is not intended for use in males, pregnant or breastfeeding individuals, or postmenopausal elderly women.

Uses of Harmoni Tablet 21's

Harmoni Tablet 21's is used to treat skin and systemic conditions due to hormone sensitivity. The detailed uses of Harmoni Tablet 21's are as follows:

  • Severe Acne: Harmoni Tablet 21's helps treat painful, deep, or inflammatory acne in women by lowering the level of male hormones (androgens) in the body, which reduces excess skin oil production.
  • Hirsutism (Excessive Hair Growth): Harmoni Tablet 21's helps reduce coarse, dark, and unwanted facial or body hair growth in women by blocking the action of androgens at the hair follicles.
  • Polycystic Ovary Syndrome (PCOS) Symptoms: Harmoni Tablet 21's helps manage symptoms of PCOS, such as irregular periods, acne, and excessive hair growth, by restoring a more balanced hormonal state.
     

Key Benefits

Harmoni Tablet 21's helps manage hormone-related conditions by addressing the effects of excess androgen activity in the body. By helping restore hormonal balance, it can improve skin health, reduce unwanted hair growth, and support more regular menstrual cycles. This medicine offers several key benefits:

  • Supports Clearer and Healthier Skin: By targeting hormonal factors that contribute to acne, Harmoni Tablet 21's helps reduce the formation of pimples, inflammatory lesions, and deep acne breakouts. This can improve skin appearance while reducing discomfort associated with acne-related inflammation.
  • Helps Reduce Unwanted Hair Growth: Harmoni Tablet 21's may help decrease excessive facial and body hair growth associated with hormonal imbalances. With continued treatment, hair may become finer, softer, and less noticeable, reducing the need for frequent hair removal.
  • Promotes More Regular Menstrual Cycles: For individuals experiencing irregular periods due to hormonal disturbances, Harmoni Tablet 21's can help establish a more predictable menstrual cycle. It may also contribute to lighter periods and reduced menstrual discomfort in some patients.
     

Directions for Use

To get the full benefit of Harmoni Tablet 21's and minimise side effects, follow these simple guidelines:

  • Take Harmoni Tablet 21's exactly as directed by your doctor.
  • Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet.
  • Take this medicine at the same time each day to maintain a steady level of hormones in your body and ensure its effectiveness.
  • You can take Harmoni Tablet 21's with or without food. If you experience mild nausea, taking it after a meal or before bed can help.
  • Always follow the specific instructions on your prescription pack, and do not stop taking this medication without consulting your doctor.
     

How Harmoni Tablet 21's Works

Harmoni Tablet 21's works through the combined action of two different hormonal components that target the root causes of hormone-related skin and hair issues. The first component is an anti-androgen. It works by blocking the effects of male hormones (androgens), which women naturally produce in small amounts. When these hormones are overactive, they overstimulate the oil glands in the skin and cause abnormal hair growth. By blocking them, this component reduces oiliness and slows down excess hair growth. The second component is a synthetic oestrogen. It supports this process by increasing the levels of a specific protein in the blood that binds to excess male hormones, making them inactive. Together, these two components regulate your hormone balance to clear your skin and manage unwanted hair.
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Alcohol

Consult your doctor

It is not known whether Harmoni Tablet 21's interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Harmoni Tablet 21's is not recommended during pregnancy. Please consult the doctor if you are pregnant or think you may be pregnant.

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Breast Feeding

Unsafe

Harmoni Tablet 21's is not recommended during lactation. Please consult the doctor if you are breastfeeding.

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Driving

Safe if prescribed

Harmoni Tablet 21's is unlikely to affect your ability to drive.

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Liver

Caution

Harmoni Tablet 21's may not be recommended for patients with severe liver disease. Please consult the doctor if you have liver problems.

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Kidney

Consult your doctor

Please consult the doctor if you have kidney problems.

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Children

Caution

Harmoni Tablet 21's is not recommended for children. It is only indicated after menarche.

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Heart

Caution

Please inform your doctor if you have heart problems before taking Harmoni Tablet 21's, as it may increase the risk of blood clots, stroke, or heart attack.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before taking Harmoni Tablet 21's, as age increases the risk of blood clots, stroke, or heart complications. A medical evaluation can help determine safer alternatives based on your health profile.

What if I have taken an overdose of Harmoni Tablet 21's

Do not take more than the prescribed dose. It is unlikely that taking more than one pill will do you any harm, but you may feel sick, vomit or have some vaginal bleeding. Talk to your doctor if you have any of these symptoms.

Diet & Lifestyle Advise

  • Maintain a gentle skincare routine: Avoid harsh scrubs or squeezing acne lesions, as this can worsen inflammation. Use non-comedogenic (won't clog pores) skincare and makeup products.
  • Focus on a low-glycaemic diet: Eating whole grains, lean proteins, and plenty of vegetables can help regulate insulin levels, which is highly beneficial if you are managing PCOS-related symptoms.
  • Stay active: Regular physical activity helps improve insulin sensitivity, manage weight, and support overall hormonal balance.
  • Limit dairy and processed sugars: Some clinical evidence suggests that reducing high-glycaemic foods and excessive dairy intake can help reduce the frequency and severity of hormonal acne breakouts.
  • Protect your skin from the sun: Hormonal therapies can sometimes make your skin more sensitive to sunlight, increasing the risk of dark patches (chloasma). Apply a broad-spectrum sunscreen daily.
     

Have a query?

How Soon It Starts Working

The time required for Harmoni Tablet 21's to start to work: The time required for Harmoni Tablet 21's to show its action is not clinically established.

The time for which the effects of Harmoni Tablet 21's last: The duration of action for Harmoni Tablet 21's is not clinically established.

What if you forget to take Harmoni Tablet 21's

If you miss a dose of Harmoni Tablet 21's, take it within the next 12 hours. If it has been more than 12 hours, skip the missed dose and take the next dose at the scheduled time.

Storage

•Store Harmoni Tablet 21's at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original blister packaging to protect them from moisture and direct light.

Drug Warnings

  • Watch for blood clot symptoms: This medication carries a small but serious risk of blood clots. Seek immediate medical care if you experience sudden chest pain, shortness of breath, or painful swelling in one leg.
  • Plan ahead for surgeries: If you are scheduled for a major surgery or will be immobilized for a long period, tell your doctor. You may need to stop taking Harmoni Tablet 21's temporarily to reduce your risk of blood clots.
  • Do not use duplicate contraception: Harmoni Tablet 21's acts as an oral contraceptive. Do not take other hormonal birth control pills, patches, or vaginal rings at the same time.
  • Attend regular health checkups: Your doctor will likely want to check your blood pressure, weight, and perform regular physical exams while you are taking this medication.
  • Do not share this medicine: This medication has been prescribed specifically for you based on your hormonal profile. Sharing it with others can be highly dangerous.
     

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Drug-Drug Interactions

  • Epilepsy and seizure medications (such as carbamazepine, phenytoin, or phenobarbital): These can speed up the removal of Harmoni Tablet 21's from your body, making it less effective.
  • Certain antibiotics and tuberculosis medications (such as rifampicin): These can reduce the therapeutic effect and contraceptive protection of Harmoni Tablet 21's.
  • Herbal supplements: Taking them can significantly lower the effectiveness of this medicine and lead to breakthrough bleeding.

Drug-Food Interactions

  • Grapefruit juice: Consuming large amounts of grapefruit juice may increase the concentration of hormones in your blood, potentially increasing the risk of side effects.

Drug-Disease Interactions

  • Circulatory and blood vessel disorders: Harmoni Tablet 21's must not be used if you have a history of deep vein thrombosis, pulmonary embolism, heart attack, or stroke, as it can increase the risk of these conditions.
  • Liver disease: If you have active liver damage or a history of liver tumours, taking this medicine can worsen your condition.
  • Severe diabetes: If you have diabetes with damaged blood vessels, this medication can worsen circulation issues.
     

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Harmoni Tablet 21's is used to treat moderate to severe symptoms of PCOS, particularly androgen-sensitive acne and hirsutism (excess hair growth) in women of reproductive age. It works by reducing the effects of male hormones (androgens), which contribute to these symptoms.
Harmoni Tablet 21's works by blocking the production of androgens (male hormones) in the ovaries.
Harmoni Tablet 21's is also a hormonal contraceptive; it should not be used in combination with other hormonal contraceptives, as this will expose the patient to an excessive dose of hormones and is not necessary for effective contraception.
Harmoni Tablet 21's does not protect against sexually transmitted diseases like HIV or Chlamydia. Only condoms can help do this.
Avoid using sunbeds or sunlamps and prolonged sunbathing whilst on treatment with Harmoni Tablet 21's as it might increase the chance of chloasma (patchy discolouration of the skin).
Harmoni Tablet 21's should be swallowed as a whole with water; do not crush or chew it. The dose will be determined by the doctor based on your condition.
If you miss a dose of Harmoni Tablet 21's, take it within the next 12 hours. If it has been more than 12 hours, skip the missed dose and take the next dose at the scheduled time.
Repeat the dose if you have vomited within 3-4 hours of taking Harmoni Tablet 21's. If it has been more than 4 hours, take the next dose at the scheduled time.
Yes, Harmoni Tablet 21's works as an oral contraceptive by preventing ovulation and reducing the likelihood of pregnancy. However, it is prescribed primarily for women with PCOS who require treatment for androgen-related symptoms such as acne or excess hair growth, rather than solely for contraception.
Harmoni Tablet 21's may cause nausea, abdominal pain, headache, weight gain and mood changes. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to consult the doctor if the side effects persist or worsen.
Improvement in acne may begin within a few weeks of starting treatment. However, hormonal treatments generally require consistent use for several months, and it may take 3 to 6 months to experience the full benefits. Continue taking the medicine as prescribed and consult your doctor if you do not notice improvement after several months.
Some women may experience minor weight changes or fluid retention when they start taking Harmoni Tablet 21's. This is usually temporary as your body adjusts to the hormones. If you notice rapid or significant weight gain, talk to your doctor.
Spotting or breakthrough bleeding between periods is common during the first few months of taking Harmoni Tablet 21's. If the bleeding is heavy, lasts for more than a few days, or occurs after you have been taking the medicine for several months, talk to your doctor.
You should highly avoid smoking while taking Harmoni Tablet 21's. Smoking significantly increases the risk of serious cardiovascular side effects, including blood clots, heart attacks, and strokes, particularly in women over the age of 35. Talk to your doctor for support with smoking cessation.
No, you must not take Harmoni Tablet 21's if you are pregnant or planning to become pregnant. If you suspect you might be pregnant while taking this medication, stop taking it immediately and talk to your doctor.
While there is no direct interaction between alcohol and Harmoni Tablet 21's, excessive alcohol intake can affect your liver function and may increase some side effects like headaches or nausea. It is always best to consume alcohol in moderation. Talk to your doctor if you have concerns about alcohol use.
You must inform your surgeon or doctor that you are taking Harmoni Tablet 21's well in advance of any planned surgery. Because of the risk of blood clots during periods of inactivity, you may need to stop taking the medication several weeks before and after the procedure. Talk to your doctor to plan this safely.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,India
Other Info - HAR0182

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