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Composition :

EMICIZUMAB-105MG

Manufacturer/Marketer :

Roche Products India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Hemlibra 105 mg Injection 0.7 ml

Hemlibra 105 mg Injection 0.7 ml is used to prevent or reduce bleeding episodes in individuals with haemophilia A. Haemophilia A is a genetic bleeding disorder caused by a deficiency or absence of clotting factor VIII that impairs blood clotting ability. It leads to prolonged bleeding episodes, often following injuries or surgeries, and can cause spontaneous internal bleeding.

Hemlibra 105 mg Injection 0.7 ml contains Emicizumab, which works by replicating the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with haemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.

The dose and duration of treatment with Hemlibra 105 mg Injection 0.7 ml may vary depending on your medical condition. The common side effects of Hemlibra 105 mg Injection 0.7 ml include redness, tenderness, warmth, or itching at the injection site, as well as joint pain and headache. Most of these side effects resolve gradually over time. However, consult the doctor if any of these persist or worsen.

Inform your doctor if you are pregnant or planning pregnancy or breastfeeding before treatment with Hemlibra 105 mg Injection 0.7 ml. Hemlibra 105 mg Injection 0.7 ml is safe for children if prescribed by the doctor. Avoid alcohol consumption while taking Hemlibra 105 mg Injection 0.7 ml to prevent unpleasant side effects. Hemlibra 105 mg Injection 0.7 ml may cause dizziness; therefore, avoid driving or operating heavy machinery unless fully alert. Inform your doctor about all the medicines you are taking and about your pre-existing health conditions.

Uses of Hemlibra 105 mg Injection 0.7 ml

Hemlibra 105 mg Injection 0.7 ml is used to prevent or reduce bleeding episodes in individuals with haemophilia A (a genetic bleeding disorder). The detailed uses of Hemlibra 105 mg Injection 0.7 ml are as follows:

  • Treatment of Hemophilia A:Hemlibra 105 mg Injection 0.7 ml is used in patients with factor VIII deficiency, reducing the frequency of spontaneous bleeding episodes.
  • Prevention of Bleeding Episodes:Hemlibra 105 mg Injection 0.7 ml helps stabilize clot formation, preventing excessive bleeding in hemophilia A patients and reduces the need for frequent factor VIII infusions, improving quality of life.

Have a query?

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Hemlibra 105 mg Injection 0.7 ml is to be used under medical supervision. With proper training in subcutaneous injection, patients may be allowed to administer it themselves.
  • Hemlibra 105 mg Injection 0.7 ml should not be injected into red or bruised areas.

Medicinal Benefits

Hemlibra 105 mg Injection 0.7 ml contains Emicizumab, which belongs to a group of medications called Monoclonal antibodies. It is used to prevent or reduce bleeding episodes in individuals with haemophilia A (a genetic bleeding disorder). Hemlibra 105 mg Injection 0.7 ml replicates the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with haemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.

How Hemlibra 105 mg Injection 0.7 ml Works

Hemlibra 105 mg Injection 0.7 ml contains Emicizumab. It works by replicating the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with hemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.

Storage

• Store in a cool and dry place away from sunlight.• Keep Hemlibra 105 mg Injection 0.7 ml out of reach and sight of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Hemlibra 105 mg Injection 0.7 ml

There is limited experience with Hemlibra 105 mg Injection 0.7 ml overdose. However, an accidental overdose could lead to increased blood clotting (hypercoagulability). In such cases, contact the doctor immediately and be closely monitored.

Drug Warnings

Inform your doctor if you are using factor VIII or a bypassing agent, as these may increase the risk of blood clots, particularly when combined with activated prothrombin complex concentrate (aPCC). You may need to stop using bypassing agents or adjust their dosage as instructed by your doctor. Also, inform your doctor about any pre-existing medical conditions and all medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements. Let your doctor know if you are pregnant or planning to become pregnant.

Diet & Lifestyle Advise

  • Eat a well-balanced diet by including plenty of fruits, vegetables, lean proteins, and whole grains to support overall health and maintain a healthy weight, which benefits joint health.
  • Stay active by choosing safe exercises to strengthen muscles and joints. This can help reduce the risk of bleeding. Consult a doctor or physical therapist for guidance.
  • Avoid risky activities by avoiding participating in sports or activities with a high risk of injury or bleeding.
  • Avoid alcohol as it may harm liver function and affect blood clotting.

Habit Forming

No

Therapeutic Class

MONOCLONAL ANTIBODIES
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Alcohol

Consult your doctor

The interaction of alcohol with Hemlibra 105 mg Injection 0.7 ml is unknown. If you have any concerns, please discuss them with your doctor.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning to become pregnant; your doctor will administer Hemlibra 105 mg Injection 0.7 ml only if the benefits outweigh the risks. Also, women who are capable of becoming pregnant must use effective contraception during and for a minimum of 6 months after stopping treatment with Hemlibra 105 mg Injection 0.7 ml.

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Breast Feeding

Consult your doctor

It is unknown if Hemlibra 105 mg Injection 0.7 ml passes into breast milk. Therefore, please inform your doctor if you are breastfeeding. Your doctor decides based on the benefits and risks of Hemlibra 105 mg Injection 0.7 ml to the mother and baby.

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Driving

Safe if prescribed

Hemlibra 105 mg Injection 0.7 ml usually does not affect your ability to drive or operate machines.

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Liver

Consult your doctor

Please inform your doctor if you have liver impairment/liver disease before receiving Hemlibra 105 mg Injection 0.7 ml.

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Kidney

Consult your doctor

Please inform your doctor if you have kidney impairment/kidney disease before receiving Hemlibra 105 mg Injection 0.7 ml.

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Children

Safe if prescribed

Hemlibra 105 mg Injection 0.7 ml is safe for children if prescribed by a doctor. The dose and duration may vary depending on the child’s weight and the severity of the child's medical condition.

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Heart

Please inform your doctor if you have heart problems before receiving Hemlibra 105 mg Injection 0.7 ml, as there is limited information available on its safety in such cases.

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Geriatrics

Safe if prescribed

Hemlibra 105 mg Injection 0.7 ml is generally safe for geriatric individuals. Please consult your doctor if you have any concerns.

FAQs

Hemlibra 105 mg Injection 0.7 ml belongs to the group of medications called Monoclonal antibodies used to prevent or reduce bleeding episodes in individuals with haemophilia A, a genetic bleeding disorder caused by a clotting factor VIII deficiency.

Hemlibra 105 mg Injection 0.7 ml contains Emicizumab. It replicates the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with hemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors.

If you use Hemlibra 105 mg Injection 0.7 ml with a bypassing agent and if you experience confusion, weakness, vomiting, stomach or back pain, less urination, chest pain, trouble breathing, coughing blood, fast heartbeat, swelling or redness in your arms or legs, eye pain, or vision issues, contact your doctor immediately.

Hemlibra 105 mg Injection 0.7 ml may cause common side effects like redness, tenderness, warmth, or itching at the injection site, joint pain, and headache. However, please consult your doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Other Info - HEM0428

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