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  2. Human Mixtard 50 40IU/ml Injection 10ml

Human Mixtard 50 40IU/ml Injection 10ml

Manufacturer

NOVO NORDISK INDIA PVT LTD

Composition

BIPHASIC ISOPHANE INSULIN-50% + INSULIN HUMAN-50%

Pack Of

1 INJECTION

In Stock

Prescription Required
Product Details

About Human Mixtard 50 40IU/ml Injection 10ml

Human Mixtard 50 40IU/ml Injection 10ml is a combination of two medicines, an intermediate-acting and a short-acting type of insulin, primarily used for the treatment of both type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in adults and children.  Diabetes mellitus is a condition that affects the way your body processes glucose. In Diabetes Mellitus Type 1, the body does not make enough insulin to control blood sugar levels. In Diabetes Mellitus type 2, either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or there is resistance to the action of insulin. As a result, insulin is produced in large amounts but it is not able to act on the organs of the body.

Human Mixtard 50 40IU/ml Injection 10ml is a dual-acting insulin that helps to lower the blood sugar (glucose) level by facilitating the uptake of glucose. It is followed by the binding of insulin to the cells of muscle and fat cells thereby inhibiting glucose release from the liver. Thus, together Human Mixtard 50 40IU/ml Injection 10ml helps to decrease blood glucose levels after the intake of meals. Besides this, it also prevents the chances of developing serious complications of diabetes like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), diabetic foot ulcer and others.

Human Mixtard 50 40IU/ml Injection 10ml should never be administered intravenously or in the vein. It is administered subcutaneously in the abdomen or thigh region. However subcutaneous injection of Human Mixtard 50 40IU/ml Injection 10ml in the abdomen region ensures faster absorption compared to other injection sites. Human Mixtard 50 40IU/ml Injection 10ml is usually given once or twice daily when both rapid and prolonged effect of insulin is desired. In the initial requirement, the dose requirement is usually between 0.3 and 1.0 IU/kg per day. However, daily insulin need may be higher in patients with insulin resistance (in puberty or obesity) and lower in patients who are also taking oral anti-diabetic medicines. An injection of Human Mixtard 50 40IU/ml Injection 10ml should be followed within 30 minutes by a meal or snack containing sugar/glucose (carbohydrates). Liver or kidney disease may reduce the requirement of Human Mixtard 50 40IU/ml Injection 10ml. On the other hand, in the conditions of infection or fever requirement of the insulin might increase. If you are not well trained to self-administer Human Mixtard 50 40IU/ml Injection 10ml, ask a healthcare professional to administer it.

In some cases, injection site reactions may occur including swelling, pain, itching, and hives. This pain can be minimized by continuous rotation of the injection site after taking Human Mixtard 50 40IU/ml Injection 10ml. These local skin reactions usually resolve in a few days to a few weeks. Besides this, you may also experience symptoms of low blood sugar (hypoglycaemia) symptoms like cold sweat, cool pale skin, nervousness or tremor, anxious feeling, unusual tiredness or weakness, confusion, difficulty in concentration, drowsiness, excessive hunger, temporary vision changes, headache, nausea, and palpitation. Most of these side effects of Human Mixtard 50 40IU/ml Injection 10ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

In type 1 diabetes, untreated high blood sugar level can lead to a life-threatening condition known as diabetic ketoacidosis. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take this medicine if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with this medicine, you should take a healthy diet, do regular exercise, and maintain weight as advised by your doctor. Human Mixtard 50 40IU/ml Injection 10ml is a cold chain medicine and so it has to be stored in the refrigerator between 2-8 degree Celsius else its efficiency may be lost. Do not store in the freezer of the refrigerator.

Uses of Human Mixtard 50 40IU/ml Injection 10ml

Type 1 diabetes mellitus, Type 2 diabetes mellitus

Directions for Use

Human Mixtard 50 40IU/ml Injection 10ml should never be administered intravenously or in the vein. It is administered subcutaneously in the abdomen or thigh region. However subcutaneous injection of Human Mixtard 50 40IU/ml Injection 10ml in the abdomen region ensures faster absorption compared to other injection sites. Human Mixtard 50 40IU/ml Injection 10ml is usually given once or twice daily when both rapid and prolonged effect of insulin is desired. In the initial requirement, the dose requirement is usually between 0.3 and 1.0 IU/kg per day. An injection of Human Mixtard 50 40IU/ml Injection 10ml should be followed within 30 minutes by a meal or snack containing sugar/glucose (carbohydrates). If you are not well trained to self-administer Human Mixtard 50 40IU/ml Injection 10ml, ask healthcare professional to administer it. Procedure for self-injecting insulin•You should wash your hand first before injecting insulin.•Then roll the insulin bottle and wipe the bottle top. •Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed.•Push the needle into the bottle and push syringe plunger down.•Now once again pull the plunger down to an appropriate number of units as prescribed by the doctor. •Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin and push the needle into the skin and then push the plunger in.•The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected.•After injecting the insulin pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Side Effects of Human Mixtard 50 40IU/ml Injection 10ml

Like all medicines, Human Mixtard 50 40IU/ml Injection 10ml can cause side effects, although not everybody gets them. You may observe common side effects such as hypoglycemia, the symptoms include cold sweat, cool pale skin, nervousness or tremor, anxious feeling, unusual tiredness or weakness, confusion, difficulty in concentration, drowsiness, excessive hunger, temporary vision changes, headache, nausea, and palpitation. All these side effects are of signs of low blood sugar level in our body known as hypoglycemia. Sometimes, hypoglycemia may lead to an unconsciousness state and may result in temporary or permanent impairment of brain function or even death. Other side effects include oedema (tissue filled with too much fluid), allergic reactions (like redness, swelling, itching and lipodystrophy or deposition of fat tissue around the injection site) might occur at the injection site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

In-Depth Precautions and Warning

Drug Warning

Human Mixtard 50 40IU/ml Injection 10ml is for subcutaneous use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin especially in patients who are at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. You are recommended not to consume alcohol as it may elevate blood glucose level. Care should be taken when you are travelling across more than 2 time zones. Your doctor may adjust your insulin schedule. Human Mixtard 50 40IU/ml Injection 10ml may decrease the level of potassium leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take this medicine if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. 

Safety Advice

  • Alcohol

    Consult Your Doctor

    You are recommended not to consume alcohol along with Human Mixtard 50 40IU/ml Injection 10ml to avoid unpleasant side-effects. Alcohol may intensify and prolong the hypoglycemic effect of insulin.

  • Pregnancy

    Please inform your doctor if you are pregnant as a dose adjustment may be required. The amount of insulin you need usually falls during the first three months of pregnancy and increases for the remaining six months.

  • Breast Feeding

    Please inform your doctor if you are breastfeeding as a dose adjustment may be required. You may be advised to alter your insulin intake or to modify your diet.

  • Driving

    Drive with caution, Human Mixtard 50 40IU/ml Injection 10ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycemia (low blood sugar).

  • Liver

    Human Mixtard 50 40IU/ml Injection 10ml to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

  • Kidney

    Human Mixtard 50 40IU/ml Injection 10ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

Other Information (HUM0056)

This item is Not Returnable.

Expires on or after - September 2021

Patients Concern

FAQs

Human Mixtard 50 40IU/ml Injection 10ml shows its effect within ½ an hour after you take it. It shows maximum effect between 2-8 hours after you take it which lasts up to 24 hours.

Insulin kept out of the refrigerator will not poison you or even make you sick. It just means that your Human Mixtard 50 40IU/ml Injection 10ml will not work as well or deliver its full potential dose. In simple terms, if your blood sugar is high, and you use the insulin that has been kept out, your blood sugar may not be lowered. In short efficacy of Human Mixtard 50 40IU/ml Injection 10ml will be decreased if not kept in the refrigerator between 2-8 degree Celsius.

The common side effects associated with Human Mixtard 50 40IU/ml Injection 10ml include low blood sugar level (which can impact the proper functioning of vital organs), stomach pain, and diarrhoea. Very rare side effects include headache, low levels of sodium, confusion, double vision, constipation, feeling unwell, redness of the skin, increased sensitivity of the skin to sunlight, itchy skin, rashes, raised, pale, red itchy bumps, and abnormal functioning of the liver.

Yes. In some cases, Human Mixtard 50 40IU/ml Injection 10ml can lower the level of potassium leading to a state of hypokalaemia. In this case, you may feel dizziness, thirst and general weakness. So, it is advisable to have regular blood sugar and potassium level check-up regularly.

Hypoglycemia refers to low blood sugar levels. Human Mixtard 50 40IU/ml Injection 10ml can cause hypoglycemia. The symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicine along with this medicine. Therefore, it is important to regularly monitor blood sugar levels. People with diabetes are advised to keep a quick source of sugar like glucose tablets, chocolate, glucose biscuits, honey, or fruit juice with them. If you experience any of the symptoms of hypoglycemia, inform your health care professional who may then adjust the dose of the medicine to better suit your needs.

Human Mixtard 50 40IU/ml Injection 10ml should be avoided in patients who are allergic to any of the components or excipients of this medicine. It should be avoided in patients suffering from moderate to severe kidney disease or liver disease. It is also not advised to use this drug if you drink too much alcohol. Make sure to inform your health care professional if you are pregnant or breastfeeding.

If Human Mixtard 50 40IU/ml Injection 10ml is taken in more than the recommended doses, it can cause mild to severe hypoglycemic episodes.

Human Mixtard 50 40IU/ml Injection 10ml

Human Mixtard 50 40IU/ml Injection 10ml

MRP: 199.70

Vial
1

10 ml Injection in 1 Vial