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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

In Duct 500mg Injection is indicated for initiating general anaesthesia (a state of heavy sleep), providing hypnosis (partial sleepiness), treating cramps, and reducing pressure in the skull in patients with increased pressure (if respiratory assistance is provided). It is also used to control seizures. It contains Thiopental sodium, which works by slowing the activity of the brain or nervous system. It creates a sleep-like state and loss of consciousness to prevent pain and discomfort during surgery.

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Whats That

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Synonym :

THIOPENTONE SODIUM, THIOPENTONE

Manufacturer/Marketer :

Ranbaxy Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About In Duct 500mg Injection

In Duct 500mg Injection belongs to the group of medicines called thiobarbiturates indicated for initiation of general anaesthesia, to provide hypnosis, as a part of treatment for cramps, and to reduce pressure in the skull in patients where the pressure is increased (if respiratory assistance is provided). It is also used to control seizures.

In Duct 500mg Injection contains Thiopental sodium, which works by slowing the activity of the brain or nervous system. It creates a sleep-like state and loss of consciousness to prevent pain and discomfort during surgery.

In some cases, In Duct 500mg Injection may cause side effects like irregular heartbeat, low blood pressure, sleepiness, coughing, and shivering. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult the doctor if you are pregnant or think you may be pregnant. Avoid breastfeeding during treatment with In Duct 500mg Injection. Do not drive or operate machinery for 24 to 36 hours after receiving In Duct 500mg Injection. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of In Duct 500mg Injection

In Duct 500mg Injection is used in the treatment of General anaesthesia, Hypnosis, Muscle cramps, Increased intracranial pressure and Seizures. The detailed uses of In Duct 500mg Injection are as follows:<br/>• Induction of General Anesthesia: In Duct 500mg Injection is used to rapidly induce unconsciousness before administering other anesthetic agents for surgical, diagnostic, or therapeutic procedures.<br/>• Short-Term Anesthetic for Brief Procedures: In Duct 500mg Injection serves as the sole anesthetic for short interventions lasting up to 15 minutes, especially when minimal painful stimuli are involved.<br/>• Control of Seizures and Convulsive States: In Duct 500mg Injection is used to manage seizures during or after anesthesia, or in emergency neurological conditions requiring sedation.<br/>• Reduction of Intracranial Pressure in Neurosurgical Patients: In Duct 500mg Injection helps lower elevated intracranial pressure when adequate ventilation is maintained, supporting brain protection during critical care.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• A healthcare professional trained in anesthesiology will administer In Duct 500mg Injection.• Do not self-administer it.

Medicinal Benefits

In Duct 500mg Injection belongs to the group of medicines called thiobarbiturates indicated for initiation of general anaesthesia (a state of heavy sleep), to provide hypnosis (partial sleepiness), as a part of treatment for cramps, and to reduce pressure in the skull in patients where the pressure is increased (if respiratory assistance is provided). It is also used to control seizures. In Duct 500mg Injection contains Thiopental sodium, which works by slowing the activity of the brain or nervous system. It creates a sleep-like state and loss of consciousness to prevent pain and discomfort during surgery.

How In Duct 500mg Injection Works

In Duct 500mg Injection contains Thiopental sodium, which works by slowing the activity of the brain or nervous system. It creates a sleep-like state and loss of consciousness to prevent pain and discomfort during surgery.

Storage

• Store in a cool and dry place away from sunlight.
• Keep In Duct 500mg Injection out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of In Duct 500mg Injection

As In Duct 500mg Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. At higher doses, In Duct 500mg Injection may produce coma and death.

Drug Warnings

Do not use In Duct 500mg Injection if you are allergic to any of its components or if you have respiratory obstruction (obstruction of the airways), asthma, myotonic dystrophy (hereditary muscle degeneration), porphyria, or severe shock. Inform the doctor if you have increased pressure in the skull, asthma or severe respiratory disorders, inflammation in the mouth, throat or jaw, heart or blood vessel disease, high blood pressure, inflammation of heart sac, hypovolemia (low blood volume), dehydration, severe bleeding or burns, myasthenia gravis, reduced function of the adrenocortical gland, severe anaemia, shock, liver or kidney impairment, metabolic disorder, addicted to alcohol or drugs of abuse. Consult the doctor if you are pregnant or think you may be pregnant. Avoid breastfeeding for at least 12 hours after the use of In Duct 500mg Injection. Let your doctor know if you are taking any prescription/non-prescription medicines or herbal supplements.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with In Duct 500mg Injection:
Co-administration of Selegiline with In Duct 500mg Injection can reduce blood pressure.

How to manage the interaction:
Taking Selegiline with In Duct 500mg Injection together can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any symptoms like lightheadedness, blurred vision, fainting or confusion, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with In Duct 500mg Injection:
Co-administration of tranylcypromine and In Duct 500mg Injection may significantly affect your blood pressure.

How to manage the interaction:
Taking tranylcypromine with In Duct 500mg Injection is not recommended as it can possibly result in an interaction. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with In Duct 500mg Injection:
Taking warfarin and In Duct 500mg Injection can reduce the blood levels of warfarin, which may make the medication less effective.

How to manage the interaction:
Although taking In Duct 500mg Injection together with Warfarin can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience chest pain, shortness of breath, sudden loss of vision, pain, redness, or swelling in an extremity, consult a doctor immediately. Do not discontinue any medicine without consulting a doctor.
ThiopentalTirzepatide
Severe
How does the drug interact with In Duct 500mg Injection:
Tirzepatide is one medication that can cause your stomach to empty more slowly. Even if you follow your doctor's orders to fast, you can still have stomach contents if you have a surgery or treatment that calls for general anesthesia with In Duct 500mg Injection. This may make indigestion more likely while under anesthesia.

How to manage the interaction:
The doctor may advise you to temporarily stop taking tirzepatide beforehand, or they may take extra precautions during anesthesia and your operation or procedure to reduce the dangers, depending on your condition and unique situation. If you have any queries or worries, speak with your physician. Your physician might be able to recommend substitutes that don't compromise the security of your anesthetic.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

SEIZURES:

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, and get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.

  • Have a seizure response plan; this helps those around you know what to do.

  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health, as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

Yes

Therapeutic Class

GENERAL ANESTHETICS

In Duct 500mg Injection Substitute

Substitutes safety advice
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Alcohol

Caution

The dose of In Duct 500mg Injection may need to be adjusted if you are addicted to alcohol or regularly consume large amounts of alcohol. Inform the doctor if you consume alcohol.

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Pregnancy

Caution

Thiopental sodium belongs to pregnancy category C. It should be used during pregnancy only if clearly needed.

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Breast Feeding

Unsafe

Thiopental sodium passes into breast milk. Avoid breastfeeding for at least 12 hours after receiving In Duct 500mg Injection.

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Driving

Unsafe

In Duct 500mg Injection has a major influence on your ability to drive and use machines. Therefore, avoid driving and operating machinery for 24 to 36 hours after receiving In Duct 500mg Injection.

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Liver

Caution

If you have a history of liver impairment, inform the doctor before receiving In Duct 500mg Injection. Your doctor may adjust the dose depending on your condition.

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Kidney

Caution

If you have a history of kidney impairment, inform the doctor before receiving In Duct 500mg Injection. Your doctor may adjust the dose depending on your condition.

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Children

Caution

Please consult the doctor if you have any concerns regarding the usage of In Duct 500mg Injection in children. The doctor may adjust the dose depending on the condition.

Have a query?

FAQs

In Duct 500mg Injection is used for initiating general anaesthesia (a state of heavy sleep), providing hypnosis (partial sleepiness), treating cramps, and reducing pressure in the skull in patients with increased pressure (if respiratory assistance is provided). It is also used to control seizures.

In Duct 500mg Injection works by slowing the activity of the brain or nervous system. Thereby, it prevents pain and discomfort during surgery.

In Duct 500mg Injection may cause low blood pressure. Therefore, if you have hypotension/low blood pressure, inform the doctor.

In Duct 500mg Injection may cause breathing difficulty. However, consult the doctor immediately if you experience difficulty breathing, rash, wheezing, hives, itching, and dizziness, as these may be signs of a severe allergic reaction.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - IND0161

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