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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Insed Nasal Spray 5 ml is used to treat Seizure clusters (acute repetitive seizures). It contains Midazolam, which increases GABA activity (a chemical messenger in the brain). Thus, it suppresses the excessive and abnormal activity of nerve cells in the brain and controls Seizures. Common side effects of Insed Nasal Spray 5 ml are headache, drowsiness, runny nose, throat irritation, and nasal discomfort.

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Whats That

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Composition :

MIDAZOLAM-0.5MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

About Insed Nasal Spray 5 ml

Insed Nasal Spray 5 ml belongs to a class of drugs called benzodiazepines used for the short-term treatment of seizure clusters. Seizure clusters are episodes of elevated seizure activity, defined as two or more seizures occurring within 24 hours. They are upsetting situations that can make you anxious, frustrated, or helpless.

Insed Nasal Spray 5 ml contains Midazolam which works by increasing GABA activity (a chemical messenger in the brain). Thus, Insed Nasal Spray 5 ml suppresses the excessive and abnormal activity of nerve cells in the brain and controls fits.

Use Insed Nasal Spray 5 ml as prescribed and for the duration as your doctor has prescribed it for you based on your medical condition. Sometimes, it may cause side effects such as headache, drowsiness, runny nose, throat irritation, and nasal discomfort. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Midazolam or other medicines. If you are pregnant, planning for pregnancy or are breastfeeding, please inform your doctor before taking Insed Nasal Spray 5 ml. Insed Nasal Spray 5 ml is not recommended for children below 12 years as the safety and effectiveness have not been established. Avoid consumption of alcohol with Insed Nasal Spray 5 ml as it may cause increased drowsiness. Avoid driving or operating machinery until you know how Insed Nasal Spray 5 ml affects you. Avoid using Insed Nasal Spray 5 ml if you have acute narrow-angle glaucoma (eye problem). Do not take Insed Nasal Spray 5 ml with opioids unless prescribed by a doctor, as it may increase the risk of breathing problems, severe drowsiness or coma.

Uses of Insed Nasal Spray 5 ml

Insed Nasal Spray 5 ml is used in the treatment of seizure clusters (acute repetitive seizures). The detailed uses of Insed Nasal Spray 5 ml are as follows:
• Conscious Sedation: Insed Nasal Spray 5 ml is used before diagnostic or therapeutic procedures to help patients feel relaxed and comfortable, and helps relieve anxiety and muscle tension before minor surgeries or dental procedures.
• Treatment of Seizure Clusters: Insed Nasal Spray 5 ml helps manage acute repetitive seizures, which involve multiple seizures within a short period and works by increasing GABA activity, a brain chemical that calms nerve cells and controls seizures.
• Pre-Surgical Sedation: Insed Nasal Spray 5 ml is administered before medical procedures to induce drowsiness and reduce discomfort and helps patients remain calm without the need for general anesthesia.

Directions for Use

• Follow your doctor's instructions regarding the dosage and duration. • Blow your nose to clear the nostrils before use. Insert the nozzle into one nostril while closing the other nostril. Spray the medicine while breathing in. Repeat for the other nostril if required. • Shake the nasal spray well before each use.

Medicinal Benefits

Insed Nasal Spray 5 ml contains Midazolam used to treat acute (sudden) repetitive fits. Insed Nasal Spray 5 ml increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent). Thus, it suppresses the excessive and abnormal activity of nerve cells in the brain and controls fits.

How Insed Nasal Spray 5 ml Works

Insed Nasal Spray 5 ml contains Midazolam which works by increasing GABA activity (a chemical messenger in the brain). Thus, Insed Nasal Spray 5 ml suppresses the excessive and abnormal activity of nerve cells in the brain and controls fits.

Storage

Store in a cool and dry place away from sunlight
Side effects of Insed Nasal Spray 5 ml
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
  • Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
  • Omega-3 supplements may support the transport of oxygen to tissues.
  • Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
  • Quit smoking, as it can worsen hypoxia.

What if I have taken an overdose of Insed Nasal Spray 5 ml

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Insed Nasal Spray 5 ml may include agitation, changes in patterns and rhythms of speech, confusion, drowsiness, dullness, feeling of sluggishness, irritability, lack of coordination, loss of consciousness, loss of strength or energy, nervousness, nightmares, problems with muscle control or coordination, relaxed and calm feeling, restlessness, shakiness and unsteady walk, sleepiness, slurred speech, talkativeness, tiredness, trouble speaking, unsteadiness, unusual excitement, unusual weak feeling, and weakness. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are allergic to Midazolam or any other medicines, please tell your doctor. If you are pregnant, planning for pregnancy, or breastfeeding, please inform your doctor before using Insed Nasal Spray 5 ml. Insed Nasal Spray 5 ml is not recommended for children below 12 years as the safety and effectiveness were not established. Avoid consumption of alcohol with Insed Nasal Spray 5 ml as it may cause drowsiness. Avoid driving or operating machinery until you know how Insed Nasal Spray 5 ml affects you. Avoid using Insed Nasal Spray 5 ml if you have acute narrow-angle glaucoma (eye problem). Do not take Insed Nasal Spray 5 ml with opioids until and unless prescribed by a doctor, as it may increase the risk of breathing problems, severe drowsiness or coma. Get medical help immediately if you experience unusually excessive sleepiness or shallow or slowed breathing while using Insed Nasal Spray 5 ml.

Drug-Drug Interactions

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MidazolamAmprenavir
Critical

Drug-Drug Interactions

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How does the drug interact with Insed Nasal Spray 5 ml:
Co-administration of Mifepristone and Insed Nasal Spray 5 ml may significantly increase Insed Nasal Spray 5 ml blood levels and effects, which increases the risk of side effects.

How to manage the interaction:
Although taking Mifepristone and Insed Nasal Spray 5 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamAmprenavir
Critical
How does the drug interact with Insed Nasal Spray 5 ml:
Co-administration of Amprenavir and Insed Nasal Spray 5 ml may significantly increase the blood levels and effects of Insed Nasal Spray 5 ml.

How to manage the interaction:
Although taking Amprenavir along with Insed Nasal Spray 5 ml can possibly lead to an interaction, they can be taken if a doctor advices them. In case of increased or prolonged drowsiness and breathing difficulties, consult a doctor. Do not stop using any medications without talking to a doctor.
MidazolamBoceprevir
Critical
How does the drug interact with Insed Nasal Spray 5 ml:
Boceprevir and Insed Nasal Spray 5 ml co-administration may considerably enhance Insed Nasal Spray 5 ml blood levels and effects.

How to manage the interaction:
Although taking Boceprevir and Insed Nasal Spray 5 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamDelavirdine
Critical
How does the drug interact with Insed Nasal Spray 5 ml:
The negative effects of Insed Nasal Spray 5 ml and Delavirdine might be increased when used together.

How to manage the interaction:
Taking Insed Nasal Spray 5 ml together Delavirdine may cause an interaction. They can, however, be taken if a doctor has prescribed them. Consult a doctor if you have any of the following symptoms: excessive sleepiness, dizziness, confusion, or weak or rapid breathing. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Insed Nasal Spray 5 ml:
Taking ceritinib and Insed Nasal Spray 5 ml may significantly increase the blood levels and effects of Insed Nasal Spray 5 ml.

How to manage the interaction:
Although taking ceritinib and Insed Nasal Spray 5 ml together may result in an interaction, they can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
MidazolamCobicistat
Critical
How does the drug interact with Insed Nasal Spray 5 ml:
Cobicistat and Insed Nasal Spray 5 ml co-administration may considerably enhance Insed Nasal Spray 5 ml blood levels and effects.

How to manage the interaction:
Although taking Cobicistat and Insed Nasal Spray 5 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamTelaprevir
Critical
How does the drug interact with Insed Nasal Spray 5 ml:
Telaprevir and Insed Nasal Spray 5 ml co-administration may considerably enhance Insed Nasal Spray 5 ml blood levels and effects.

How to manage the interaction:
Although taking Telaprevir and Insed Nasal Spray 5 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamSodium oxybate
Critical
How does the drug interact with Insed Nasal Spray 5 ml:
Sodium oxybate and Insed Nasal Spray 5 ml co-administration may considerably enhance Insed Nasal Spray 5 ml blood levels and effects.

How to manage the interaction:
Although taking Sodium oxybate and Insed Nasal Spray 5 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Insed Nasal Spray 5 ml:
Atazanavir and Insed Nasal Spray 5 ml co-administration may considerably enhance Insed Nasal Spray 5 ml blood levels and effects.

How to manage the interaction:
Although taking Atazanavir and Insed Nasal Spray 5 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Insed Nasal Spray 5 ml:
Indinavir and Insed Nasal Spray 5 ml co-administration may considerably enhance Insed Nasal Spray 5 ml blood levels and effects.

How to manage the interaction:
Although taking Indinavir and Insed Nasal Spray 5 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise and maintain a healthy body weight.
  • Maintain a diet rich in fruits, vegetables and whole grains. Avoid fried foods, high-fat dairy products, pastries and processed foods, as they may worsen anxiety.
  • Follow a regular sleep pattern. Do not take a nap during the daytime.
  • Avoid watching tv and using mobiles or laptops just before bedtime.
  • Avoid the consumption of alcohol as it may increase drowsiness.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

Avoid consumption of alcohol with Insed Nasal Spray 5 ml as it may increase drowsiness.

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Pregnancy

Caution

If you are pregnant or planning for pregnancy, inform your doctor before using Insed Nasal Spray 5 ml. Babies born to mothers receiving Insed Nasal Spray 5 ml late in pregnancy may be at risk of feeding or breathing problems, withdrawal symptoms or dangerously low body temperature.

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Breast Feeding

Caution

Insed Nasal Spray 5 ml may be excreted in breast milk and may harm your baby. Therefore, discuss with your doctor the best way to feed your baby if you use Insed Nasal Spray 5 ml.

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Driving

Caution

Avoid driving or operating machinery until you know how Insed Nasal Spray 5 ml affects you.

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Liver

Consult your doctor

If you have liver problems, consult your doctor before using Insed Nasal Spray 5 ml.

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Kidney

Consult your doctor

If you have kidney diseases/conditions, consult your doctor before using Insed Nasal Spray 5 ml.

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Children

Unsafe

Insed Nasal Spray 5 ml is not recommended for children below 12 years as the safety and effectiveness were not established.

Have a query?

FAQs

Insed Nasal Spray 5 ml is used to treat Seizure clusters (acute repetitive seizures).

Insed Nasal Spray 5 ml contains Midazolam, which works by increasing the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent). Thereby preventing fits by stabilizing the electrical activity of nerve cells in the brain.

If the seizure cluster continues after 10 minutes of the first dose, you can use the second dose of Insed Nasal Spray 5 ml if advised by your doctor. However, the second dose should be given in the other nostril. Do not use more than two doses to treat a seizure cluster.

You are not recommended to take Insed Nasal Spray 5 ml with opioids, alcohol or other central nervous system depressants as it may cause breathing problems, severe drowsiness or coma. Therefore, please consult your doctor before taking Insed Nasal Spray 5 ml with any other medicines.

You are not recommended to stop using Insed Nasal Spray 5 ml suddenly without consulting your doctor as it may cause withdrawal symptoms such as hallucinations, nervousness, shaking, muscle pain or cramps. Therefore, use Insed Nasal Spray 5 ml for as long as your doctor has prescribed it, and if you experience any difficulty while using Insed Nasal Spray 5 ml, please consult your doctor so that the dose may be reduced gradually.

Yes, Insed Nasal Spray 5 ml may cause physical dependence if used for prolonged periods. Therefore, use Insed Nasal Spray 5 ml only in the dose and for the duration as advised by your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - INS0039

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