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compositionComposition:INSULIN HUMAN-40IU
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Prescription Medicine
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Insugen-R 40IU/ml Injection is used for the treatment of diabetes mellitus in both children (above two years of age) and adults. It mimic the insulin in humans, which helps your body utilize glucose (sugar) for energy. It works by ensuring rapid and consistent sugar control. It is a fast-acting form of insulin that helps lower blood sugar levels after food intake. Prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses sugar production in the liver. It may cause common side effects such as hypokalaemia (low potassium), hypoglycaemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin) at the injection site.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

INSULIN HUMAN-40IU

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Insugen-R 40IU/ml Injection

Insugen-R 40IU/ml Injection is an injectable prescription medicine used to control high blood sugar in adults and children with diabetes. It helps manage both type 1 and type 2 diabetes by replacing or supplementing the body's natural hormone, helping to prevent long-term health complications. Regular use of this medication helps prevent long-term complications associated with poorly controlled blood sugar levels.

For the best results, you must inject Insugen-R 40IU/ml Injection consistently as directed by your doctor. The timing of your injection in relation to meals is crucial for preventing sudden drops or spikes in blood sugar. Along with regular injections, adopting a balanced diet and regular physical activity plays a critical role in managing your condition.

While using Insugen-R 40IU/ml Injection, you may experience mild side effects, with low blood sugar (hypoglycemia) being the most common. It is vital to monitor your blood sugar levels regularly and consult your doctor immediately if you experience serious symptoms like confusion, extreme sweating, or a fast heartbeat.

Talk to your doctor before starting Insugen-R 40IU/ml Injection if you have kidney problems, liver damage, or heart conditions. Do not take this if you are experiencing an episode of low blood sugar or if you have a known allergy to any of its ingredients.

Certain medications, alcohol, and smoking can significantly affect how Insugen-R 40IU/ml Injection works, which may lead to sudden blood sugar changes. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your healthcare provider before using Insugen-R 40IU/ml Injection. Insulin requirements may change throughout pregnancy, and more frequent blood sugar monitoring is often necessary to maintain optimal glucose control and support the health of both mother and baby. 

Uses of Insugen-R 40IU/ml Injection

Insugen-R 40IU/ml Injection is used to control blood sugar levels in people with diabetes by replacing or supplementing the insulin that the body needs to regulate glucose effectively.

  • Type 1 Diabetes Mellitus: Insugen-R 40IU/ml Injection replaces the insulin that the body can no longer produce, helping glucose move from the bloodstream into cells where it can be used for energy.
  • Type 2 Diabetes Mellitus: Insugen-R 40IU/ml Injection helps lower blood sugar levels when diet, exercise, and oral diabetes medications alone are not sufficient to achieve adequate glucose control.

Key Benefits

Insugen-R 40IU/ml Injection plays a vital role in maintaining healthy blood sugar levels and reducing the risk of diabetes-related complications.

  • Provides reliable blood sugar control: It helps keep blood glucose levels within the target range, reducing daily fluctuations and improving overall diabetes management.
  • Relieves symptoms of high blood sugar: Effective glucose control can help reduce symptoms such as excessive thirst, frequent urination, fatigue, and blurred vision.
  • Reduces the risk of long-term complications: Consistent blood sugar management helps lower the risk of diabetes-related complications affecting the nerves, kidneys, eyes, and cardiovascular system.
  • Supports overall health and wellbeing: Maintaining stable blood glucose levels can improve energy levels and help support normal daily activities.
  • Allows flexible diabetes management: Insugen-R 40IU/ml Injection can be tailored to individual treatment plans and adjusted according to blood sugar monitoring, diet, and lifestyle needs.
Side effects of Insugen-R 40IU/ml Injection 10 ml
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

To achieve effective blood sugar control, Insugen-R 40IU/ml Injection should be used exactly as prescribed by your doctor or diabetes care team.

  • Insugen-R 40IU/ml Injection is administered as a subcutaneous (under-the-skin) injection.
  • Follow your healthcare provider's instructions carefully regarding the dose, timing, preparation, and injection technique.
  • Inject the medication into recommended areas such as the abdomen, thigh, buttocks, or upper arm.
  • Clean the injection site before administering the dose.
  • Rotate injection sites regularly to help prevent skin thickening, hard lumps, or other injection-site changes.
  • Do not inject into skin that is bruised, tender, red, swollen, scarred, or otherwise damaged.
  • Avoid rubbing or massaging the injection site after administration, as this may affect insulin absorption.
  • Monitor your blood sugar levels as directed by your healthcare provider and follow any dietary or lifestyle recommendations that form part of your diabetes management plan.

How Insugen-R 40IU/ml Injection Works

Insugen-R 40IU/ml Injection works by mimicking the natural hormone produced by your pancreas. When you inject Insugen-R 40IU/ml Injection, it enters your bloodstream and binds to specific receptors on your cells. This action acts like a key, opening up the cells in your muscles and fat tissues so they can absorb sugar from your blood to use for energy. At the same time, Insugen-R 40IU/ml Injection signals your liver to stop producing and releasing extra sugar into the blood. By facilitating sugar absorption and stopping excess sugar production, it effectively lowers your overall blood sugar levels.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Insugen-R 40IU/ml Injection to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

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Pregnancy

Safe if prescribed

Insugen-R 40IU/ml Injection can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery.

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Breast Feeding

Safe if prescribed

Insugen-R 40IU/ml Injection can be given safely to nursing mothers but only under the supervision of a physician.

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Driving

Unsafe

Drive with caution, Insugen-R 40IU/ml Injection usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

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Liver

Caution

Insugen-R 40IU/ml Injection to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Insugen-R 40IU/ml Injection to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Insugen-R 40IU/ml Injection can be given safely to children provided; dose has to be prescribed by a child specialist.

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Heart

Caution

Insugen-R 40IU/ml Injection should be administered with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Insugen-R 40IU/ml Injection.

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Geriatrics

Caution

Insugen-R 40IU/ml Injection should be administered with caution in elderly patients. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Insugen-R 40IU/ml Injection

Do not take more than the prescribed dose of Insugen-R 40IU/ml Injection as it may cause overdose and lead to low blood sugar or low blood potassium. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Maintain Consistent Meal Timing: Eat your meals and snacks at consistent times throughout the day to match the activity of your Insugen-R 40IU/ml Injection injection and prevent sudden drops in blood sugar.
  • Monitor Carbohydrate Intake: Monitor your daily carbohydrate intake closely, as carbs have the most direct impact on your blood sugar levels.
  • Be Prepared for Low Blood Sugar: Always carry a fast-acting source of sugar, such as glucose tablets, candy, or fruit juice, to quickly treat unexpected episodes of low blood sugar.
  • Exercise Safely: Engage in regular physical activity, but monitor your blood sugar before, during, and after exercise, as physical exertion can lower your blood sugar levels.
  • Stay Hydrated and Limit Alcohol: Stay well-hydrated by drinking plenty of water, and limit your alcohol intake, as alcohol can unpredictably affect your blood sugar levels.

Have a query?

How Soon It Starts Working

The time required for Insugen-R 40IU/ml Injection to start to work: Insugen-R 40IU/ml Injection ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Insugen-R 40IU/ml Injection last: The effect of Insugen-R 40IU/ml Injection lasts for 6 to 8 hours.

What if you forget to take Insugen-R 40IU/ml Injection

If you are using this medication on a regular schedule and you miss a dose, consult your doctor. Do not double the dose to catch up.

Storage

• Store unopened Insugen-R 40IU/ml Injection vials or pens in a refrigerator between 2°C and 8°C.• Do not freeze Insugen-R 40IU/ml Injection. Discard any insulin that has been frozen, even if it has thawed.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the medicine before use: Always inspect the solution before injecting; it should be clear and colourless (or uniformly cloudy if it is a pre-mixed suspension), without any unusual clumps or particles.
  • Rotate injection sites regularly: Always rotate your injection site with each dose to prevent skin thickening or lumpy deposits (lipodystrophy).
  • Do not reuse needles or syringes: Never reuse needles or syringes, as this increases the risk of infection and blockages in the needle.
  • Never share injection devices: Never share your Insugen-R 40IU/ml Injection pen, syringe, or needle with another person, even if the needle has been changed, to avoid spreading infections.
  • Verify your medicine before each injection: Always check the label of your medicine before injecting to ensure you are using the correct type and strength of Insugen-R 40IU/ml Injection.
  • Know your insulin formulation: Insugen-R 40IU/ml Injection is available in different formulations. Regular human insulin is a clear, short-acting insulin typically taken around mealtimes, while NPH insulin is a cloudy, intermediate-acting insulin that provides longer-lasting blood sugar control. Always verify which formulation you have been prescribed before administration.
  • Continue insulin during illness unless advised otherwise: Never stop taking insulin during illness unless specifically instructed by your doctor. During periods of fever, infection, vomiting, or other illnesses, your blood sugar levels may become more difficult to control and may require closer monitoring.
  • Seek medical advice if blood sugar becomes difficult to control: If you are unable to eat, have persistent vomiting, or notice consistently high blood sugar readings during illness, contact your healthcare provider promptly for advice.
  • Store insulin properly: If an unopened vial or pen has been left unrefrigerated, exposed to excessive heat, or left in a hot vehicle, consult your pharmacist or healthcare provider before using it, as the medication may no longer be effective.

Drug-Drug Interactions

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Drug-Drug Interactions

Insugen-R 40IU/ml Injection can interact with several medications that may either increase or decrease its blood sugar-lowering effects.

  • Other diabetes medications: Using Insugen-R 40IU/ml Injection together with other antidiabetic medicines may increase the risk of low blood sugar (hypoglycaemia).
  • Beta-blockers: These medicines can mask common warning signs of low blood sugar, such as a rapid heartbeat and tremors, making hypoglycaemia more difficult to recognise.
  • ACE inhibitors: In some patients, ACE inhibitors may enhance insulin sensitivity and increase the risk of hypoglycaemia, although this effect is generally less pronounced than with other glucose-lowering medications.
  • Corticosteroids: These medications can raise blood sugar levels and may reduce the effectiveness of Insugen-R 40IU/ml Injection.
  • Thyroid medications: Changes in thyroid hormone levels can affect blood glucose control and may alter insulin requirements.
  • Diuretics (water tablets): Certain diuretics may increase blood sugar levels, making diabetes management more challenging.


Drug-Food Interactions

Certain dietary factors can influence blood sugar control while using Insugen-R 40IU/ml Injection.

  • Alcohol: Drinking alcohol may increase the risk of low blood sugar and can impair your ability to recognise symptoms of hypoglycaemia. Alcohol consumption should be discussed with your healthcare provider.


Drug-Disease Interactions

Certain medical conditions may affect how your body responds to Insugen-R 40IU/ml Injection.

  • Kidney disease: Reduced kidney function may slow the removal of insulin from the body, increasing the risk of hypoglycaemia and potentially requiring dose adjustments.
  • Liver disease: Impaired liver function can affect blood sugar regulation and insulin metabolism, increasing the likelihood of low blood sugar episodes and the need for careful monitoring.

Drug-Drug Interactions

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How does the drug interact with Insugen-R 40IU/ml Injection 10 ml:
Coadministration of Gatifloxacin with Insugen-R 40IU/ml Injection 10 ml may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Insugen-R 40IU/ml Injection 10 ml can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised.
How does the drug interact with Insugen-R 40IU/ml Injection 10 ml:
Taking Insugen-R 40IU/ml Injection 10 ml with ciprofloxacin effects blood glucose levels, which may cause hyperglycemia (high blood sugar) or hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking ciprofloxacin and Insugen-R 40IU/ml Injection 10 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor if you experience headaches, dizziness, sleepiness, anxiety, disorientation, tremors, nausea, hunger, weakness, increased sweating, and a rapid heartbeat, increased hunger, increased thirst. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Insugen-R 40IU/ml Injection is used to treat Type 1 diabetes mellitus and type 2 diabetes mellitus.
Insugen-R 40IU/ml Injection can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Insugen-R 40IU/ml Injection can be given to you or not, depending on your present condition. Insugen-R 40IU/ml Injection should be avoided in patients who are allergic to Insugen-R 40IU/ml Injection or other forms of insulin, patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).
Cold sweat; cool pale skin; headache; rapid heartbeat; feeling sick; feeling very hungry; temporary vision changes; drowsiness; unusual tiredness and weakness; nervousness or tremor; feeling anxious; feeling confused; difficulty in concentrating are some of the common signs of the low blood sugar level in an individual.
If you experience low blood sugar, eat glucose tablets or another high sugar snack (e.g. sweets, biscuits, fruit juice). Measure your blood sugar if possible and rest. Always carry glucose tablets or high sugar snacks with you. You should give a call to any of your family members if you are feeling dizziness or drowsiness.
Local allergic reactions (pain, redness, hives, inflammation, bruising, swelling and itching) at the injection site may occur. These usually disappear after a few weeks of taking your insulin. If they do not disappear, or if they spread throughout your body, talk to your doctor immediately.
Human insulin is a laboratory created by growing insulin proteins within E-coli bacteria (Escherichia coli).
You are recommended to avoid white bread, maida, poori, naan, noodles, biryani, fried rice, corn flakes, cheese, ice creams, milkshakes, beef, pork, sugarcane juice, soft drinks, sweetened health drinks and beverages. Also, avoid mango, custard apple, jack fruit, fruit salads with ice cream, and fruit-based desserts.
No, do not stop taking Insugen-R 40IU/ml Injection without consulting your doctor as it may lead to high blood sugar levels and may worsen your condition resulting in complications. If you experience any side effects or discomfort, contact your doctor. You may need dose adjustment.
Taking Insugen-R 40IU/ml Injection at the same site may cause local irritation, itching and lump formation. Therefore, it is best to avoid taking injections at the same site or maintain a gap of at least one day.
Maintain a diet that includes chapatis, puffed rice with vegetables, multigrain bread, plain cooked dal, roasted grams soups, sprouts, cooked vegetables with less oil, steamed vegetables, orange, jamun, guava, watermelon, apple, papaya, curd, cow’s milk, thin buttermilk, fish (baked, grilled, or steamed), cashew nuts, peanuts, and walnuts (handful). Avoid alcohol consumption and quit smoking. Exercise regularly and brisk walk daily for 30 minutes. Also, limit intake of sugar.
The risk factors for developing low blood sugar levels include not taking adequate meals or skipping meals, excessive insulin use, too much alcohol intake, fever and too much exercise. Some medications, like other diabetes medicine glimepiride, medicines used for fever and pain (salicylates), ramipril, etc., can result in such episodes when used with insulin. Inform your doctor about these episodes as you may need dose adjustment.
The side effects of Insugen-R 40IU/ml Injection include local injection site reactions, low blood sugar, low potassium, itchy skin, rash, weight gain, and swelling due to fluid retention. If these side effects persist or worsen, please consult your doctor.
No, you should never use Insugen-R 40IU/ml Injection if it has been frozen, even if it has thawed. Freezing destroys the structure of the medicine, making it ineffective. Throw it away and use a new vial or pen. Talk to your pharmacist if you have questions about storage.
You should only mix Insugen-R 40IU/ml Injection with other insulins if your doctor has specifically instructed you to do so and showed you the correct technique. Some types of insulin cannot be mixed. Talk to your doctor or pharmacist for guidance.
The preferred injection sites are your abdomen (stomach area), thighs, buttocks, or the back of your upper arms. The abdomen absorbs the medicine fastest. Talk to your doctor about the best rotation routine for you.
Maintaining good blood sugar control is very important during pregnancy for both mother and baby. Insugen-R 40IU/ml Injection is commonly used during pregnancy, but your dose may need to be adjusted. Talk to your doctor to manage your treatment plan safely.
You should avoid or limit alcohol while using Insugen-R 40IU/ml Injection. Alcohol can cause your blood sugar to drop unexpectedly and can hide the warning signs of low blood sugar. Talk to your doctor before drinking alcohol.
If your medicine looks cloudy (when it is supposed to be clear), contains floating particles, has changed color, or has been frozen, it is no longer safe to use. Always inspect the vial or pen before each injection. Talk to your pharmacist if you are unsure.
Skipping a meal after injecting Insugen-R 40IU/ml Injection can lead to severe low blood sugar (hypoglycemia) because the medicine will lower your blood sugar without food to balance it. Always coordinate your injections with your meal times as directed by your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - INS0008
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