How does Intacept 50mg Injection work?

Intacept 50mg Injection consists of Etanercept, which belong to TNF (Tumor necrosis factor) inhibitor class of drug. It works by inhibiting the TNF-ÃŽÂ± and TNF-ÃŽÂ² binding to the cell surface and therby makes the TNF cytokine inactive. This helps reduce inflammation and pain caused due to various autoimmune diseases.

Who should not take Intacept 50mg Injection?

Intacept 50mg Injection affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis, hepatitis B, or abnormal liver enzymes. Intacept 50mg Injection can also increase the risk of developing cancers; hence, mentioning your doctor if you have a history of any cancer is essential.

Is Intacept 50mg Injection a disease-modifying anti-rheumatic drug?

Yes, Intacept 50mg Injection is a disease-modifying anti-rheumatic drug (DMARD) that works by inhibiting tumour necrosis factor (TNF), a key protein involved in the inflammatory response. By blocking TNF, it helps reduce inflammation, manage symptoms of autoimmune diseases like rheumatoid arthritis, and slow disease progression.

Is Intacept 50mg Injection a steroid or monoclonal antibody?

Intacept 50mg Injection is neither a steroid nor a monoclonal antibody. It is a biological medicine classified as a TNF inhibitor. It is a fusion protein that binds to tumour necrosis factor (TNF) and prevents it from causing inflammation in autoimmune conditions like rheumatoid arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, and plaque psoriasis.

Is Intacept 50mg Injection safe?

Yes, Intacept 50mg Injection is safe as it is administered by the doctor or nurse in prescribed dose and duration. Ensure you do not skip scheduled appointments to maintain safety and monitor your progress effectively.

Does Intacept 50mg Injection cause weight gain?

Intacept 50mg Injection may cause weight gain if you use it for a longer duration. If you notice any weight changes, manage stress, exercise regularly, eat a nutritious-rich diet, take a fibre-rich diet, stay hydrated, and cut down on sugary foods and drinks.

Does Intacept 50mg Injection cause hair loss?

Intacept 50mg Injection may cause hair loss in some individuals. If you experience this symptom, manage stress, use gentle hair care practices, and eat nutritious rich food. However, if hair loss persists consult the doctor for further guidance.

How long does Intacept 50mg Injection take to work?

Intacept 50mg Injection typically starts to show some effects within one to two weeks. However, it may take 3 to 6 months for noticeable improvement.

What are the side effects of Intacept 50mg Injection?

The side effects of Intacept 50mg Injection include tingling or numbness, shortness of breath, bleeding, dizziness, pale skin, bruising, vision problems, redness on the skin and arms, and injection site reactions. Consult the doctor if any of these symptoms persist or worsen.

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Written By Lakshmithulasi Yarragunta ,

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Intacept 50mg Injection is used to treat Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, and Plaque psoriasis. It contains Etanercept, which works by blocking the effects of TNF-alpha, a pro-inflammatory cytokine that becomes elevated in psoriasis, rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, and ankylosing spondylitis. Common side effects of this medication include tingling or numbness, dizziness, shortness of breath, bleeding, pale skin, bruising, vision problems, redness on the skin and arms, and injection site reactions.

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About Intacept 50mg Injection

Intacept 50mg Injection is an immunosuppressant medicine that helps reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, and plaque psoriasis. Intacept 50mg Injection is generally used alone or in combination with methotrexate medicine.

Intacept 50mg Injection consists of Etanercept, which belongs to the TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused due to various autoimmune diseases.

Intacept 50mg Injection may cause certain side effects such as tingling or numbness, dizziness, shortness of breath, bleeding, pale skin, bruising, vision problem, redness on the skin and arms, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. Intacept 50mg Injection is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

Intacept 50mg Injection should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, Hepatitis B Virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. Intacept 50mg Injection may cause dizziness, so drive only if you are alert and focused. Intacept 50mg Injection should not be given to children under two years of age as safety has not been established. Avoid consuming alcohol along with Intacept 50mg Injection as it could lead to increased dizziness and risk of liver damage. Intacept 50mg Injection is not recommended for use in pregnant and nursing mothers as it can cause serious adverse effects on the baby.

Uses of Intacept 50mg Injection

Treatment of Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis and Plaque psoriasis

Directions for Use

Intacept 50mg Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Intacept 50mg Injection consists of Etanercept, which belongs to TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce pain, redness, and inflammation (swelling) in patients with rheumatoid arthritis, ankylosing spondylitis, and other autoimmune disorders.

How Intacept 50mg Injection Works

Intacept 50mg Injection consists of Etanercept, which belongs to the TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-Î± and TNF-Î² binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused due to various autoimmune diseases.

Storage

Store in a cool and dry place away from sunlight

Side effects of Intacept 50mg Injection

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Inflammation Of Air Passages In Lungs

Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:

If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
Regularly track your symptoms and report any changes or concerns to your healthcare provider.

Bladder Infection

Bladder infection needs immediate medical attention when you observe blood in urine or have any abnormal changes in your body.
Get a physical examination and blood tests to identify factors that led to infection and initiate the treatment process immediately.
Avoid anxiety and stress, as it can worsen your condition.
Follow your doctor's instructions, and there can be medication with antibiotics and other supportive vitamins.
Take a balanced diet to prevent negative changes in your body.

Redness Of The Skin

Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Itching

Here are the few steps for dealing with itching caused by drug use:

Report the itching to your doctor immediately; they may need to change your medication or dosage.
Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
Try not to scratch, as this can worsen the itching and irritate your skin.
If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Pain

Apply a hot/cold pack to the affected area.
Doing gentle exercises can help cope with pain by stretching muscles.
Get enough sleep. It helps enhance mood and lower pain sensitivity.
Avoid alcohol, smoking and tobacco as they can increase pain.
Follow a well-balanced meal.
Meditation and massages may also help with pain.

Common Cold

Here are the steps to manage the medication-triggered Upper respiratory tract infection:

Inform your doctor about the symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Intacept 50mg Injection

Since Intacept 50mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Intacept 50mg Injection should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, Hepatitis B Virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), and diabetes as it can worsen your health condition. Do not take live vaccines while being treated with Intacept 50mg Injection to prevent any serious consequences. Intacept 50mg Injection may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol along with Intacept 50mg Injection as it could lead to increased dizziness and risk of stomach bleeding/ulcers. Intacept 50mg Injection is not recommended for use in children below two years of age as safety and efficacy is not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interactions

EtanerceptHydrocortisone

Severe

EtanerceptAzathioprine

Severe

Drug-Drug Interactions

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EtanerceptHydrocortisone

Severe

How does the drug interact with Intacept 50mg Injection:
The use of Intacept 50mg Injection and Hydrocortisone can increase the risk of infections.

How to manage the interaction:
Co-administration of Intacept 50mg Injection and hydrocortisone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

EtanerceptAzathioprine

Severe

How does the drug interact with Intacept 50mg Injection:
When Intacept 50mg Injection is used with Azathioprine, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Azathioprine and Intacept 50mg Injection, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

EtanerceptAzacitidine

Severe

How does the drug interact with Intacept 50mg Injection:
When Intacept 50mg Injection is used with Azacitidine, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Intacept 50mg Injection and Azacitidine, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

EtanerceptCytarabine

Severe

How does the drug interact with Intacept 50mg Injection:
When Intacept 50mg Injection is used with Cytarabine, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Cytarabine with Intacept 50mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

EtanerceptBosutinib

Severe

How does the drug interact with Intacept 50mg Injection:
Using Intacept 50mg Injection together with bosutinib may increase the risk of infections.

How to manage the interaction:
Although there is an interaction between Bosutinib and Intacept 50mg Injection, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience diarrhea, sore throat, muscle aches, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.

EtanerceptFludarabine

Severe

How does the drug interact with Intacept 50mg Injection:
When Intacept 50mg Injection is used with Fludarabine, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Intacept 50mg Injection with Fludarabine can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

EtanerceptVoclosporin

Severe

How does the drug interact with Intacept 50mg Injection:
When Intacept 50mg Injection is used with Voclosporin, the risk of severe infections, as well as certain cancers, increases.

How to manage the interaction:
Although taking Intacept 50mg Injection and Voclosporin together can cause an interaction, it can be taken if a doctor has suggested it. If you develop a fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

EtanerceptCiclosporin

Severe

How does the drug interact with Intacept 50mg Injection:
When Intacept 50mg Injection is taken with cyclosporine, it can increase the risk of infections.

How to manage the interaction:
Although taking Intacept 50mg Injection and ciclosporin together can result in an interaction, it can be taken if a doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

EtanerceptOxaliplatin

Severe

How does the drug interact with Intacept 50mg Injection:
When Intacept 50mg Injection is used with Oxaliplatin, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Oxaliplatin and Intacept 50mg Injection, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

EtanerceptGemcitabine

Severe

How does the drug interact with Intacept 50mg Injection:
Taking Intacept 50mg Injection with Gemcitabine can increase the risk of infections.

How to manage the interaction:
Taking Intacept 50mg Injection with Gemcitabine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
Massages can also be helpful.
Avoid freezing and hot temperatures.
Avoid wearing tight-fitting clothes; instead, wear loose garments.
Rest well and get plenty of sleep.
To avoid developing pressure sores, change your position at least every two hours.
Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

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Alcohol

Unsafe

Avoid alcohol consumption as alcohol intake, along with Intacept 50mg Injection, may cause increased dizziness and risk of stomach bleeding/ulcers.

Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant, or planning pregnancy inform your doctor before receiving Intacept 50mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass in to breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Intacept 50mg Injection. Your doctor may suggest you to stop feeding while on treatment with this medicine

Driving

Unsafe

Intacept 50mg Injection may make you feel dizzy and sleepy. Do not drive or operate machinery if you experience dizziness or drowsiness.

Liver

Caution

Intacept 50mg Injection should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment. However, Intacept 50mg Injection is not recommended in patients with active liver diseases.

Kidney

Caution

Intacept 50mg Injection should be used with caution if you have kidney impairment. Dose adjustment may be needed in patients with liver impairment.

Children

Caution

Intacept 50mg Injection is not recommended in children below two years of age as the safety and efficacy is not established. In children above two years of age, it will be administered by the paediatrician.

FAQs

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Other Info - INT0366

Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:44 PM IST

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Intacept 50mg Injection Substitute

Etacept Pfs 50 mg Injection 1 ml

ENBREL 50MG INJECTION

Rymti 50 mg Injection 1 ml

Etacept Pfs 50 mg Injection 1 ml

ENBREL 50MG INJECTION

Rymti 50 mg Injection 1 ml

FAQs

What is the use of Intacept 50mg Injection?

How does Intacept 50mg Injection work?

Who should not take Intacept 50mg Injection?

Is Intacept 50mg Injection a disease-modifying anti-rheumatic drug?

Is Intacept 50mg Injection a steroid or monoclonal antibody?

Is Intacept 50mg Injection safe?

Does Intacept 50mg Injection cause weight gain?

Does Intacept 50mg Injection cause hair loss?

How long does Intacept 50mg Injection take to work?

What are the side effects of Intacept 50mg Injection?

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