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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Intalfa 5 miu Injection is used for the treatment of Follicular cancer, Hairy cell carcinoma, Malignant melanoma, AIDS-Related Kaposi's Sarcoma, Hodgkin's Lymphoma, Chronic hepatitis B, and Chronic hepatitis C. It contains Interferon alpha 2b as an active ingredient, which belongs to the class of immunomodulators. It works by inhibiting the abnormal growth of cancer cells. On the other hand, it also helps reduce the amount of hepatitis C virus (HCV) in the body.

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Intalfa 5 miu Injection

Intalfa 5 miu Injection is an anti-cancer medicine used in the treatment of hairy cell leukaemia, follicular leukaemia, malignant leukaemia, AIDS-Related Kaposi’s Sarcoma, Hodgkin’s Lymphoma in combination with anthracycline-containing chemotherapy medicine, chronic hepatitis B and C. Cancer is a disease where the cells grow abnormally and divide uncontrollably. It can also be used when the cancer has spread to other parts of the body.

Intalfa 5 miu Injection contains Interferon alpha 2b as an active ingredient, which belongs to the class of immunomodulators. It works by inhibiting the abnormal growth of cancer cells. It also helps reduce the amount of hepatitis C virus (HCV) in the body. 

Intalfa 5 miu Injection may cause certain side effects such as flu-like symptoms, diarrhoea, fatigue, nausea, headache, dizziness, vomiting, tiredness, and injection site reactions. If the side effects persist or bother you, consult your doctor. Intalfa 5 miu Injection will be administered by a trained doctor. Hence, do not self-administer.

Avoid taking it and inform your doctor if you are allergic to Intalfa 5 miu Injection or its components. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, autoimmune hepatitis, a history of autoimmune disease, or HIV infection, as it can cause adverse effects. $ is not recommended for use in pregnancy as it is known to cause fetal harm. Breastfeeding should be avoided when on treatment with Intalfa 5 miu Injection.

Uses of Intalfa 5 miu Injection

Intalfa 5 miu Injection is used in the treatment of Follicular cancer, Hairy cell carcinoma, Malignant melanoma, AIDS-Related Kaposi's Sarcoma, Hodgkin's Lymphoma, Chronic hepatitis B, and Chronic hepatitis C. The detailed uses of Intalfa 5 miu Injection are as follows:<br/>• Chronic Hepatitis B: Intalfa 5 miu Injection is used to manage chronic hepatitis B by stimulating the immune system to suppress viral replication. This helps reduce liver inflammation and lowers the risk of long-term liver damage. It's often used when other treatments aren't ideal or effective.<br/>• Chronic Hepatitis C: Intalfa 5 miu Injection is used alongside other antivirals, this medication enhances the body's antiviral defenses to lower HCV levels. It may slow the disease's progression and improve liver health over time.<br/>• Hairy Cell Leukemia: Intalfa 5 miu Injection slows the growth of abnormal white blood cells in this rare blood cancer. It's especially helpful in patients not eligible for more aggressive treatments. Over time, it can improve blood counts and disease control.<br/>• Follicular Lymphoma: In this slow-growing type of lymphoma, Intalfa 5 miu Injection is used to inhibit cancer cell activity. It may be given alone or with chemotherapy to improve response rates. It prolongs remission and helps maintain long-term disease control.<br/>• Malignant Melanoma: Intalfa 5 miu Injection reduces the risk of melanoma recurrence in high-risk patients. It works by boosting immune activity against cancer cells. Though side effects can be intense, it offers survival benefits for some.<br/>• Kaposi’s Sarcoma (AIDS-related): Especially helpful in AIDS patients, Intalfa 5 miu Injection helps reduce the size and spread of cancerous skin lesions. The drug activates the immune system to attack tumor cells. Its effectiveness may vary depending on immune status and HIV treatment.<br/>• Genital Warts (HPV-related): Intalfa 5 miu Injection used to treat stubborn or recurrent warts caused by human papillomavirus. It enhances immune recognition of infected cells to clear them more effectively. Usually used in patients who haven’t responded to topical therapies.<br/>• Multiple Myeloma: Intalfa 5 miu Injection inhibits the growth of malignant plasma cells. It may be used to maintain remission in select cases. More often, it complements other chemotherapy or immunotherapy strategies.<br/>• Non-Hodgkin’s Lymphoma: In some types of NHL, Intalfa 5 miu Injection acts as an immune modulator to inhibit cancer development. It may extend progression-free survival when used alongside chemotherapy. Its use depends on the subtype and stage of disease.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Intalfa 5 miu Injection will be administered by a doctor or nurse in a healthcare facility.• Do not self-administer.

Medicinal Benefits

Intalfa 5 miu Injection contains Interferon alpha 2B, which is used for treating patients with different types of cancer. This medicine works by inhibiting the abnormal growth of cancer cells. It also helps reduce the amount of hepatitis C virus (HCV) in the body.

How Intalfa 5 miu Injection Works

Intalfa 5 miu Injection contains Interferon alpha 2b as an active ingredient, which belongs to the class of immunomodulators. It works by inhibiting the abnormal growth of cancer cells. It also helps reduce the amount of hepatitis C virus (HCV) in the body.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Intalfa 5 miu Injection out of reach and sight of children.
• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Intalfa 5 miu Injection
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Try eating smaller meals (4-5 times) instead of large ones to make it easier on your stomach.
  • Avoid foods that are spicy, fatty, or high in insoluble fibre.
  • Consuming soluble fibre (such as psyllium) can help with constipation, and probiotics may reduce bloating and discomfort.
  • Stay away from carbonated drinks, alcohol, caffeine, and smoking, as they can upset your stomach.
  • Reducing stress, losing weight, and exercising regularly for 20-30 minutes can help improve digestion and reduce stomach issues.
  • Poor sleep can worsen stomach problems, so focus on good sleep habits or use tools like Sleepio to improve your sleep.

What if I have taken an overdose of Intalfa 5 miu Injection

As Intalfa 5 miu Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Intalfa 5 miu Injection may cause nausea/vomiting that doesn't stop, chest pain, stomach/abdominal pain, and dark urine.

Drug Warnings

Intalfa 5 miu Injection should be avoided if you are allergic to it or any other components of this medicine. Before taking Intalfa 5 miu Injection, inform your doctor if you have any cardiovascular conditions, liver/kidney disease, autoimmune hepatitis, a history of autoimmune disease, or HIV infection, as it can cause adverse effects.. Intalfa 5 miu Injection may cause fetal harm. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Breastfeeding should be discontinued in nursing mothers during the treatment. Intalfa 5 miu Injection is not recommended for use in children as the safety and efficacy are not established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Intalfa 5 miu Injection:
When Intalfa 5 miu Injection is taken with Eltrombopag, it can lower the metabolism of Eltrombopag.

How to manage the interaction:
There may be a possibility of interaction between Eltrombopag and Intalfa 5 miu Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to call a doctor right away. These symptoms include chronic hepatitis C, advanced liver disease, cirrhosis, liver failure, and other liver-related problems. You should also seek medical attention if you experience confusion, fever, joint pain, swelling, or any other unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Intalfa 5 miu Injection:
Coadministration of Intalfa 5 miu Injection with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Taking Baricitinib with Intalfa 5 miu Injection together can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
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Alcohol

Caution

It is unknown whether Intalfa 5 miu Injection interacts with alcohol. Consult your doctor for more information.

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Pregnancy

Unsafe

Intalfa 5 miu Injection is not recommended for use in pregnancy as it may cause fetal toxicity and harm your foetus. Hence, if you are pregnant or planning to be pregnant, inform your doctor before receiving Intalfa 5 miu Injection.

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Breast Feeding

Unsafe

Intalfa 5 miu Injection should not be taken if you are breastfeeding, as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine.

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Driving

Caution

Intalfa 5 miu Injection will be administered to hospitalized patients. Driving is not recommended.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Intalfa 5 miu Injection. Intalfa 5 miu Injection may cause liver impairment. Hence, inform your doctor if you observe any symptoms such as jaundice, dark-coloured urine, or nausea. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Limited data are available on the effect of Intalfa 5 miu Injection in kidney-impaired patients. If you have a pre-existing or a history of kidney disease, inform your doctor.

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Children

Unsafe

Intalfa 5 miu Injection is not recommended for use in children below 18 years as the safety and efficacy are not established.

Have a query?

FAQs

Intalfa 5 miu Injection is used to treat Follicular cancer, Hairy cell carcinoma, Malignant melanoma, AIDS-Related Kaposi’s Sarcoma, Hodgkin’s Lymphoma, Chronic hepatitis B, and Chronic hepatitis C

Intalfa 5 miu Injection contains Interferon alpha 2b, which works by inhibiting the abnormal growth of cancer cells. It also helps reduce the amount of hepatitis C virus (HCV) in the body.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - INT0226

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