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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Intazumab 30 mg Injection 1's is used in the treatment of Breast cancer. It contains Pertuzumab as an active ingredient, which belongs to the class of monoclonal antibodies. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in mammalian cells; this causes inhibition of the cancer cell growth and, finally, initiating apoptosis. Intazumab 30 mg Injection 1's is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

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Composition :

PERTUZUMAB-30MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Intazumab 30 mg Injection 1's

Intazumab 30 mg Injection 1's is an anti-cancer medicine used in the treatment of Breast cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. The abnormal growth of cancer (malignant) cells in the breast is known as breast cancer. Intazumab 30 mg Injection 1's is combined with trastuzumab and docetaxel for treating patients with HER2-positive metastatic breast cancer who have not received any chemotherapy for metastatic breast cancer. This medicine is also used in combination with docetaxel and trastuzumab as a neoadjuvant treatment of breast cancer in patients with HER2-positive (human epidermal growth factor receptor 2) or as part of a complete treatment regimen for early breast cancer.

Intazumab 30 mg Injection 1's contains Pertuzumab as a active ingredient which belongs to the class of monoclonal antibodies. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Intazumab 30 mg Injection 1's may cause certain side effects such as fatigue, nausea, headache, vomiting, dizziness, hair loss, constipation, dry skin, myalgia, upper respiratory tract infections, diarrhea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Intazumab 30 mg Injection 1's. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Intazumab 30 mg Injection 1's should be avoided if you are allergic to it or any other components of this medicine. Intazumab 30 mg Injection 1's may cause left ventricular dysfunction, anaphylaxis, or hypersensitivity reactions during the treatment. Hence, careful observation should be performed for any reactions in the patient. If any changes or hypersensitivity reactions occur, treatment should be discontinued. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease, as it can cause adverse effects. Intazumab 30 mg Injection 1's is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. The use of Intazumab 30 mg Injection 1's along with the doxorubicin-containing regimen is not established. Hence, if you are on such treatment, inform your doctor before starting the treatment. Intazumab 30 mg Injection 1's is not recommended for use in children as the safety and efficacy are not established.

Uses of Intazumab 30 mg Injection 1's

Intazumab 30 mg Injection 1's is used in the treatment of Breast Cancer. The detailed uses of Intazumab 30 mg Injection 1's are as follows:

  • Metastatic HER2-Positive Breast Cancer: Intazumab 30 mg Injection 1's is used in combination with trastuzumab and docetaxel as a first-line treatment for patients who haven’t received prior anti-HER2 therapy for metastatic disease.
  • Neoadjuvant Therapy: Intazumab 30 mg Injection 1's is given before surgery to shrink tumors in locally advanced or early-stage HER2-positive breast cancer.
  • Adjuvant Therapy: Intazumab 30 mg Injection 1's is used after surgery in patients with early-stage HER2-positive breast cancer who are at high risk of recurrence.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Intazumab 30 mg Injection 1's will be administered by a nurse or doctor.
  • Do not self-administer.

Medicinal Benefits

Intazumab 30 mg Injection 1's contains Pertuzumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis. Intazumab 30 mg Injection 1's is used in combination with trastuzumab and docetaxel for the treatment of breast cancer.

How Intazumab 30 mg Injection 1's Works

Intazumab 30 mg Injection 1's contains Pertuzumab as a active ingredient which belongs to the class of monoclonal antibodies. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Intazumab 30 mg Injection 1's out of the sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Intazumab 30 mg Injection 1's

Since Intazumab 30 mg Injection 1's is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Intazumab 30 mg Injection 1's may cause diarrhoea, alopecia, neutropenia, nausea, fatigue, rash, and/or peripheral neuropathy, and left ventricular dysfunction (i.e. cardiotoxicity).

Drug Warnings

Intazumab 30 mg Injection 1's should be avoided if you are allergic to it or any other components of this medicine. Intazumab 30 mg Injection 1's may cause left ventricular dysfunction, anaphylaxis, or hypersensitivity reactions during the treatment. Hence, careful observation should be performed for any reactions in the patient. If any changes or hypersensitivity reactions occur, treatment should be discontinued. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease, as it can cause adverse effects. Intazumab 30 mg Injection 1's is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. The use of Intazumab 30 mg Injection 1's along with the doxorubicin-containing regimen is not established. Hence, if you are on such treatment, inform your doctor before starting the treatment. Intazumab 30 mg Injection 1's is not recommended for use in children as the safety and efficacy are not established.

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

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Alcohol

Unsafe

Alcohol intake might increase the risk of worsening your condition. Hence, avoid alcohol consumption till your condition improves.

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Pregnancy

Unsafe

Intazumab 30 mg Injection 1's is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Intazumab 30 mg Injection 1's. Use reliable methods of birth control while on treatment with Intazumab 30 mg Injection 1's.

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Breast Feeding

Caution

It is not known whether Intazumab 30 mg Injection 1's is excreted in breast milk. Hence, if you are breastfeeding, inform your doctor before receiving Intazumab 30 mg Injection 1's. Your doctor will weigh the benefits and the risks before prescribing this medicine.

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Driving

Caution

Intazumab 30 mg Injection 1's will be administered in the hospital setting. Driving is not recommended while on therapy.

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Liver

Caution

No clinical trials have assessed the impact of hepatic impairment on the pharmacokinetics of Intazumab 30 mg Injection 1's. Hence, if you have a pre-existing or a history of liver disease, inform your doctor.

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Kidney

Caution

Limited data are available on the effect of Intazumab 30 mg Injection 1's in kidney-impaired patients. Hence, if you have a pre-existing or a history of kidney disease, inform your doctor.

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Children

Unsafe

Intazumab 30 mg Injection 1's is not recommended for use in children as the safety and efficacy are not established.

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Heart

Intazumab 30 mg Injection 1's may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Intazumab 30 mg Injection 1's.

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Geriatrics

Safe if prescribed

Intazumab 30 mg Injection 1's is generally considered safe when used under medical supervision in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

FAQs

Intazumab 30 mg Injection 1's is used to treat Breast Cancer.

Intazumab 30 mg Injection 1's contains Pertuzumab, which works by inhibiting the excess production of a protein called human epidermal growth factor receptor 2 (HER2) in mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Inform your doctor whether you have received any other breast cancer treatment containing doxorubicin in your medication list. Intazumab 30 mg Injection 1's may cause left ventricular dysfunction, anaphylaxis, hypersensitivity reactions, and embryo-fetal toxicity during the treatment. Hence, inform your oncologist if you have any cardiovascular conditions, liver/kidney disease, are pregnant, are planning to become pregnant, or are breastfeeding before receiving Intazumab 30 mg Injection 1's.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - INT0632

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Keep Refrigerated. Do not freeze.

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