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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Invokana 100 mg Tablet is used to treat type 2 diabetes in people whose sugar levels are too high and cannot be controlled by diet and exercise alone. It contains Canagliflozin, which works by inhibiting the reabsorption of glucose in the body, resulting in an increase in glucose excretion through urine. The removal of excessive glucose helps to lower the blood sugar level. Additionally, it also lowers high blood pressure due to increased diuretic effect (water loss) and reduced body weight due to a reduction in glucose availability. In some cases, you may experience urinary tract infections, changes in urination (urinating more frequently or in larger amounts, urgent need to urinate, need to urinate at night), constipation, feeling thirsty, nausea, dizziness, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

CANAGLIFLOZIN-100MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Invokana 100 mg Tablet

Invokana 100 mg Tablet is used to treat Type 2 diabetes. Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups to lead a normal life.

Invokana 100 mg Tablet contains empagliflozin, which works by blocking the sodium-glucose co-transporter-2 (SGLT-2) enzyme. This lowers renal reabsorption of glucose and increases urine excretion of glucose via inhibiting SGLT2. As a result, it lowers blood sugar levels in diabetics.

Not everyone who is taking Invokana 100 mg Tablet will get these side effects. In some cases, you may experience certain common side effects such as thrush, pain or a burning feeling when you pee, peeing more than normal, and mild skin rash or itchy skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently.

Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. The dosage is based on your medical condition and response to treatment. To help you remember, take it at the same time each day. Tell your doctor if your condition does not improve or worsens (if your blood sugar is too high or too low).

Do not consume Invokana 100 mg Tablet if you are allergic to any component present in Invokana 100 mg Tablet . If you are pregnant or breastfeeding, consult your doctor before taking Invokana 100 mg Tablet . Avoid drinking alcohol while taking Invokana 100 mg Tablet since it may produce unpleasant side effects. Inform your doctor about all of the medications you are taking, as well as your medical history, to rule out any undesirable side effects or interactions.

Uses of Invokana 100 mg Tablet

Invokana 100 mg Tablet is used in the treatment of Type 2 Diabetes Mellitus. The detailed uses of Invokana 100 mg Tablet are as follows:

  • Blood Sugar Control: Invokana 100 mg Tablet is primarily used to manage type 2 diabetes by lowering blood sugar levels when combined with a suitable diet and exercise regimen.
  • Weight Loss Aid: Invokana 100 mg Tablet medication may support weight loss in individuals with type 2 diabetes by reducing calorie absorption and food intake.
  • Cardiovascular Benefits: Invokana 100 mg Tablet has shown potential in lowering the risk of cardiovascular events in diabetic patients, making it particularly beneficial for those prone to heart-related conditions.
  • Kidney Health: Invokana 100 mg Tablet helps protect kidney function in individuals with type 2 diabetes, reducing the likelihood of developing diabetic nephropathy.
  • Improvement in Glycemic Control: Invokana 100 mg Tablet enhances glycemic control by enabling the body to excrete excess glucose through urine, effectively lowering overall blood sugar levels.

Directions for Use

• Invokana 100 mg Tablet can be taken with or without food, but it is best to take it before the first meal of the day. • It is usually taken once daily or as prescribed by your doctor. • Swallow Invokana 100 mg Tablet as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

  • Invokana 100 mg Tablet plays a vital role in managing diabetes and achieving good control of blood sugar levels by delaying the absorption of sugar and increasing insulin sensitivity in the body.
  • Invokana 100 mg Tablet does not cause a sudden lowering of the blood glucose level or cause significant hypoglycaemia.
  • In the prediabetic condition, Invokana 100 mg Tablet is the only recommended treatment available.
  • Invokana 100 mg Tablet also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), loss of sensation in your hands and feet (diabetic neuropathy) or even loss of a foot.

How Invokana 100 mg Tablet Works

Invokana 100 mg Tablet contains Canagliflozin, a sodium-glucose cotransporters-2 (SGLT-2) (a protein present in the kidney) inhibitor that works by inhibiting the reabsorption of glucose in the body, resulting in an increase in glucose excretion through urine. The removal of excessive glucose helps to lower the blood sugar level. Additionally, it also lowers high blood pressure due to increased diuretic effect (water loss) and reduced body weight due to a reduction in glucose availability.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Invokana 100 mg Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • High sugar intake can promote yeast growth, which is a common cause of balanoposthitis. Reduce consumption of sugary drinks, processed foods, and excessive sweets.
  • A well-balanced diet rich in fruits, vegetables, whole grains, and lean protein supports overall health and immune function, which can help prevent infections.
  • Staying well-hydrated is important for overall health and may help prevent balanoposthitis by keeping the urinary tract healthy.
  • Take warm water sitz baths, use saline baths, and use over-the-counter talcum powders.
  • Thoroughly dry the area after washing.
  • Avoid harsh soaps, detergents, and scented products in the genital area.
  • Use topical antifungal agents like bacitracin.
  • Eat a balanced diet rich in fruits, vegetables, and whole grains to support overall health.
  • Incorporate probiotic-rich foods like yogurt or kefir into your diet to promote gut health.
  • Practice good genital hygiene by washing with warm water and avoiding harsh soaps.
  • Wear loose, breathable cotton underwear to reduce moisture buildup.
  • Avoid douching and scented soaps that can disrupt natural vaginal balance.
  • Stay dry and change out of wet clothes promptly to prevent yeast growth.
  • Limit excessive sugar consumption to reduce yeast growth.
  • Consider adding antifungal foods like garlic or turmeric to your diet.
  • Reduce stress levels by practicing calming techniques such as mindfulness, meditation, or controlled breathing exercises.
  • Complete the full course of prescribed antifungal treatment to prevent recurrence.
  • Consult your doctor if you experience frequent or severe yeast infections.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Invokana 100 mg Tablet

Do not take more than the prescribed dose of Invokana 100 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Before taking this medication, tell your doctor or pharmacist if you are allergic to any of its contents.
  • Invokana 100 mg Tablet should not be stopped even if you feel better, without consulting your doctor, as your sugar level keeps changing. If you stop taking Invokana 100 mg Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy).
  • Please inform your doctor if you have heart disease.
  • It may be harder to control your blood sugar when your body is stressed (such as when you have a fever, infection, injury, or surgery).
  • Also, if you eat less or cannot eat due to these conditions or any illness, this can lead to other side effects while taking this medication.
  • Before surgery, tell your doctor or dentist about all the products you use (including prescription, nonprescription, and herbal products).
  • Be alert for signs of low blood sugar (hypoglycemia), such as sweating, dizziness, dry mouth, dry skin, fast heartbeat, shivering, intense thirst, or frequent urination. If you experience any of these symptoms, take honey or sugar candies right away.
  • Invokana 100 mg Tablet works best when coupled with a healthy lifestyle like losing weight if you are overweight (BMI>25), eating fewer calories (low fat and sugary food), and being more physically active (at least 150min of activity every week).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Invokana 100 mg Tablet:
Co-administration of Invokana 100 mg Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Invokana 100 mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Invokana 100 mg Tablet:
Co-administration of Morphine with Invokana 100 mg Tablet may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Invokana 100 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should engage themself in regular exercise like cycling, running, walking, jogging, dancing, or swimming for at least 30 minutes. Try to invest at least 150 minutes weekly in exercise.
  • A person should also maintain a healthy body weight to avoid obesity or high blood sugar; it can increase the risk of the onset of diabetes.
  • A person should take low fat and a low sugar diet. For that, replace carbohydrates with whole grains, fruits, and vegetables as carbohydrates changed into sugars leading to high blood sugar levels.
  • Try to avoid potatoes as they are high glycaemic foods that increase the risk of high sugar in the blood.
  • A person should limit the consumption of alcohol and quit smoking.
  • Keep your blood pressure as normal (120/80) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Unsafe

You should avoid consuming alcohol with Invokana 100 mg Tablet as it may alter your blood sugar levels or lead to serious side effects.

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Pregnancy

Consult your doctor

Invokana 100 mg Tablet is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels the benefit outweighs the risk. You should not take Invokana 100 mg Tablet without a doctor's advice.

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Breast Feeding

Consult your doctor

There is no sufficient data on how Invokana 100 mg Tablet affects breastfeeding. It is safe to seek medical advice before you start Invokana 100 mg Tablet if you are breastfeeding.

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Driving

Caution

Invokana 100 mg Tablet should not affect your ability to drive or operate machinery/tools.

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Liver

Caution

Invokana 100 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Invokana 100 mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor depending on your renal functions. Invokana 100 mg Tablet is not recommended in severe kidney disease. Regular monitoring of kidney function tests is therefore important if you're taking Invokana 100 mg Tablet .

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Children

Caution

Invokana 100 mg Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

Have a query?

FAQs

Invokana 100 mg Tablet is used to treat type 2 diabetes, also called 'non-insulin-dependent diabetes.

Invokana 100 mg Tablet is a type of medicine known as a sodium-glucose cotransporter-2 (SGLT2) inhibitor used for the treatment of type -2 diabetes. It lowers blood sugar levels by blocking the action of SGLT-2 in the kidney and removing excess sugar from your body through urination.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Do not stop taking Invokana 100 mg Tablet until your prescribed course is finished, even if you feel better.

Once blood sugar goes below the normal range (70mg/dl), it is called hypoglycemia or low blood sugar. If you feel your sugar level is going down and feel weak, immediately eat sugar candies. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you if you have diabetes.

Type 2 diabetes mellitus is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. The symptoms include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision.

During the treatment with Invokana 100 mg Tablet , maintain a healthy diet and do regular exercise to control blood sugar levels. Avoid skipping any dose of Invokana 100 mg Tablet , as it may cause fluctuations in your blood sugar levels. Tell your doctor about all of your medical conditions and any other medications that you are taking.

No, Invokana tablet and metformin are not the same. Though, both the medicines are used to treat Type 2 diabetes mellitus, their mechanisms of action are different.

Take Invokana 100 mg Tablet with or without food as prescribed by your doctor. Try to take it at the same time every day. Swallow it as whole with a glass of water. Do not crush, break or chew it.

Record your blood sugar levels, either daily or on a regular basis so that you can show them to your doctor on your next visit. Your doctor will examine these reports and let you know whether Invokana 100 mg Tablet is working or not.

Patients with a history of amputation are more prone to lower limb amputation. Patients with foot ulcers or sores, as well as those who have or had heart disease, are also at high risk. Additionally, patients who have or have suffered from neuropathy (nerve damage that causes numbness, tingling, and pain, usually in your hands and feet) and peripheral vascular disease (narrowing of blood vessels in feet, legs, or arms causing numbness, pain, or coldness) are also at high risk of lower limb amputation.

Invokana 100 mg Tablet usually causes loss of fat mass which typically results in weight loss. However, this may differ from person to person depending upon the doses and whether it is being used alone or with other diabetes medications.

The serious side effects of Invokana 100 mg Tablet are sudden kidney impairment, ketoacidosis (increased ketones in your blood or urine), low blood sugar, some allergic reaction, and serious urinary tract infections. Although it is rare, Invokana 100 mg Tablet may also cause a severe bacterial infection that may damage the tissue beneath the skin in the perineum (area between and around the anus and genitals). Invokana 100 mg Tablet may weaken your bones, increasing the risk of fractures, especially in the wrists, upper arms, or hands.

Country of origin

Italy

Manufacturer/Marketer address

Corporate Communications, Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - INV0037

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