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compositionComposition:ITRACONAZOLE-200MG
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Prescription Medicine
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ITRACONAZOLE-200MG

Manufacturer/Marketer :

Maestro Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Itrafab-200 Capsule

Itrafab-200 Capsule is an antifungal medicine used to treat a wide variety of fungal infections. It is commonly prescribed for infections affecting the nails, skin, mouth, throat, or lungs. By stopping the growth of fungi, this medicine helps clear the infection and prevents it from spreading.

To get the best results, you must take Itrafab-200 Capsule consistently at the same times every day as directed by your healthcare provider. If you are taking the capsule form, it is highly recommended to take it with a full meal to ensure your body absorbs the medication properly. Keeping your skin clean and dry and wearing breathable cotton clothing can also support your recovery.

While taking Itrafab-200 Capsule , some people may experience mild side effects like an upset stomach, nausea, or headaches. However, you must contact your doctor immediately if you experience signs of liver damage, such as yellowing of the skin or eyes, dark urine, or severe fatigue.

Talk to your doctor before starting this medicine if you have a history of heart problems, liver disease, or kidney issues. Do not take this if you have heart failure or a history of congestive heart failure, as this medication can make these conditions worse.

Itrafab-200 Capsule can interact with several other medications, including certain blood thinners, cholesterol-lowering drugs, and acid reducers, which can lower its effectiveness. Avoid drinking alcohol while taking this medicine, as it can increase the risk of liver damage. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before using this medicine.

Uses of Itrafab-200 Capsule

Your doctor may prescribe Itrafab-200 Capsule to treat several conditions, including:

  • Fungal nail infections (onychomycosis): Itrafab-200 Capsule helps clear fungal infections in both toenails and fingernails, allowing healthy, normal nails to grow back over time.
  • Ringworm and athlete's foot (tinea infections): It treats stubborn skin infections by stopping the spread of the fungus on the surface of the skin, relieving itching and scaling.
  • Thrush (oral candidiasis): It clears yeast infections in the mouth and throat, reducing pain and making swallowing comfortable again.
  • Systemic fungal infections: It treats deeper, more serious fungal infections that can affect internal organs like the lungs, helping your body fight off the infection.

Key Benefits

Itrafab-200 Capsule offers reliable relief from the uncomfortable symptoms of fungal infections, helping you return to your normal daily routine.

  • Targeted clearance: It works directly at the site of the infection, whether deep in the nail bed or on the skin surface.
  • Convenient oral routine: Being an oral medication, it treats widespread or deep-seated infections that topical creams cannot reach.
  • Long-lasting protection: The medicine remains in your skin and nail tissues for some time even after you finish the course, helping prevent the infection from returning.
Side effects of Itrafab-200 Capsule
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Directions for Use

Itrafab-200 Capsule offers reliable relief from the uncomfortable symptoms of fungal infections, helping you return to your normal daily routine.

  • Targeted clearance: It works directly at the site of the infection, whether deep in the nail bed or on the skin surface.
  • Convenient oral routine: Being an oral medication, it treats widespread or deep-seated infections that topical creams cannot reach.
  • Long-lasting protection: The medicine remains in your skin and nail tissues for some time even after you finish the course, helping prevent the infection from returning.

How Itrafab-200 Capsule Works

Itrafab-200 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of the cell membranes of fungi). This weakens and damages the fungal cell membranes that are essential for their survival, as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.
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Alcohol

Unsafe

Avoid consumption of alcohol with Itrafab-200 Capsule as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Itrafab-200 Capsule is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Itrafab-200 Capsule .

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Breast Feeding

Consult your doctor

Itrafab-200 Capsule is excreted in human milk and may harm the baby. Therefore, Itrafab-200 Capsule is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Unsafe

Itrafab-200 Capsule may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Itrafab-200 Capsule .

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Liver

Caution

Take Itrafab-200 Capsule with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Itrafab-200 Capsule with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Itrafab-200 Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.

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Heart

Unsafe

Itrafab-200 Capsule is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Caution

Elderly patients taking Itrafab-200 Capsule should maintain caution during the treatment, as it is known to cause side effects like hearing loss or age-related problems.

What if I have taken an overdose of Itrafab-200 Capsule

Do not take more than the prescribed dose of Itrafab-200 Capsule as it may cause serious adverse effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Take with acidic drinks if needed: If you take stomach acid reducers, taking Itrafab-200 Capsule capsules with an acidic drink like cola can help your body absorb the medicine better.
  • Keep infected areas dry: Fungi thrive in warm, moist environments. Dry your skin thoroughly after showering, especially between your toes and in skin folds.
  • Wear breathable clothing: Choose loose-fitting cotton clothing and breathable leather or canvas shoes to reduce moisture buildup.
  • Avoid sharing personal items: Do not share towels, nail clippers, socks, or footwear with others to prevent spreading or re-infecting yourself.

Have a query?

How Soon It Starts Working

  • The time required for Itrafab-200 Capsule to start to work: Itrafab-200 Capsule ideally shows its action within 5 hours after administration.
  • The time for which the effects of Itrafab-200 Capsule last: The effect of Itrafab-200 Capsule lasts for 16 to 28 hours.

What if you forget to take Itrafab-200 Capsule

If you miss a dose of Itrafab-200 Capsule , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Itrafab-200 Capsule at room temperature, ideally between 15°C and 25°C (59°F to 77°F). • Keep the medication in its original container, tightly closed, to protect it from light and direct moisture.

Drug Warnings

  • Monitor your liver: Your doctor may require regular blood tests to check your liver function while you are taking this medicine.
  • Check the oral liquid: If you are using the liquid form, inspect the solution before use; it should be clear and free of particles.
  • Watch for heart failure signs: Stop taking the medication and seek emergency care if you develop unexpected shortness of breath or swelling in your ankles.
  • Limit acid reducers: Avoid taking antacids within 2 hours of taking Itrafab-200 Capsule capsules, as they can prevent the medicine from being absorbed properly.

Drug-Drug Interactions

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Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Acid reducers (antacids, PPIs): May lower the absorption of Itrafab-200 Capsule , making it less effective.
  • Statins (cholesterol-lowering drugs): Itrafab-200 Capsule can increase the levels of these drugs in your blood, increasing the risk of muscle damage.
  • Blood thinners: Taking Itrafab-200 Capsule with certain blood thinners can increase the risk of bleeding.
  • Heart rhythm medications: Combining these can lead to serious, life-threatening heart rhythm issues.

 

Drug-Food Interactions:

  • Grapefruit juice: Avoid drinking grapefruit juice, as it can interfere with how your body processes Itrafab-200 Capsule and increase the risk of side effects.
  • Full meals: Itrafab-200 Capsule capsules require food in the stomach to be properly absorbed, whereas the oral solution should not be taken with food.

 

Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking Itrafab-200 Capsule , as it may worsen your condition or cause complications.

  • Heart failure: May worsen heart failure symptoms; avoid use if you have active heart failure.
  • Liver disease: Itrafab-200 Capsule is processed by the liver, so existing liver disease increases the risk of serious liver damage.
  • Kidney disease: May affect how the medicine is cleared from your body, requiring careful monitoring by your doctor.
ItraconazoleErgotamine
Critical

Drug-Drug Interactions

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How does the drug interact with Itrafab-200 Capsule:
The blood levels and effects of ticagrelor may be greatly increased when combined with Itrafab-200 Capsule.

How to manage the interaction:
Itrafab-200 Capsule and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleErgotamine
Critical
How does the drug interact with Itrafab-200 Capsule:
The blood levels and effects of ergotamine may be greatly increased when combined with Itrafab-200 Capsule.

How to manage the interaction:
Ergotamine and Itrafab-200 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you experience a severe headache, shortness of breath, blurred vision, confusion, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of the fingers or toes, pale or cold skin, or chest pain or tightness. Without first consulting your doctor, never stop taking medicines.
How does the drug interact with Itrafab-200 Capsule:
The blood levels and effects of solifenacin may be greatly increased when combined with Itrafab-200 Capsule.

How to manage the interaction:
Solifenacin and Itrafab-200 Capsule may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Itrafab-200 Capsule:
The blood levels and effects of felodipine may be considerably increased by taking Itrafab-200 Capsule together with felodipine.

How to manage the interaction:
Although there is a possible interaction between felodipine and Itrafab-200 Capsule, they can be taken if prescribed by a doctor. Consult a physician if you have an irregular heartbeat, Edema (accumulation of fluid in hands or legs), or abnormally low blood pressure. Without first consulting a doctor, never stop taking medicines.
ItraconazoleNisoldipine
Critical
How does the drug interact with Itrafab-200 Capsule:
The blood levels and effects of nisoldipine may be greatly increased when used with Itrafab-200 Capsule.

How to manage the interaction:
Nisoldipine and Itrafab-200 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Itrafab-200 Capsule:
The blood level of Cisapride may be significantly raised by combining Cisapride with Itrafab-200 Capsule.

How to manage the interaction:
Despite the possibility of an interaction when cisapride and Itrafab-200 Capsule are combined, they can be taken if a doctor prescribes them. Consult a doctor if you develop any side symptoms, such as fainting, lightheadedness, dizziness, or rapid or pounding heartbeats. Without consulting a doctor, never stop taking any medication. Note: Cisapride is no longer available in the market.
How does the drug interact with Itrafab-200 Capsule:
Coadministration of Itrafab-200 Capsule with Silodosin can increase the blood levels and effects of Silodosin, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Itrafab-200 Capsule with Silodosin together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Itrafab-200 Capsule:
Co-administration of Tolvaptan and Itrafab-200 Capsule may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Itrafab-200 Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Itrafab-200 Capsule:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Itrafab-200 Capsule along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Itrafab-200 Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Itrafab-200 Capsule:
Co-administration of Methylergometrine and Itrafab-200 Capsule may increase the blood levels of Methylergometrine.

How to manage the interaction:
Methylergometrine and Itrafab-200 Capsule may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Itrafab-200 Capsule may impair the absorption of Itrafab-200 Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Itrafab-200 Capsule.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Itrafab-200 Capsule is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.

You are not recommended to take Itrafab-200 Capsule with simvastatin, as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark-coloured urine, fever, or flu-like symptoms. However, please consult a doctor before using Itrafab-200 Capsule with other medicines.

Itrafab-200 Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itrafab-200 Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itrafab-200 Capsule and consult a doctor immediately.

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Itrafab-200 Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Itrafab-200 Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itrafab-200 Capsule , please consult your doctor.

Inform your doctor if you are sexually active and discuss effective contraception methods. Itrafab-200 Capsule may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Itrafab-200 Capsule .

Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Itrafab-200 Capsule may interact with other medicines. Also, let your doctor know if you are stopping any medicine.

Itrafab-200 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.

The side effects of Itrafab-200 Capsule include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.

If you have taken overdose of Itrafab-200 Capsule , please consult your doctor immediately.

Store Itrafab-200 Capsule at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

It is best to avoid alcohol while taking Itrafab-200 Capsule . Both alcohol and this medicine are processed by the liver, and combining them can increase your risk of liver damage. Talk to your doctor if you have concerns.

Nail infections take time to clear because the healthy nail must grow out. While the medicine starts working immediately to stop the fungus, you may not see the full results until several months after completing your treatment. Talk to your doctor if you do not notice improvement.

No, Itrafab-200 Capsule is generally not recommended during pregnancy as it can harm an unborn baby. You should use effective birth control while taking this medicine and for several weeks after stopping it. Talk to your doctor for safer alternatives.

Yes, if you are taking the capsule form, you should take it with a full meal to help your body absorb it. If you are taking the oral solution, it should be taken on an empty stomach. Talk to your doctor or pharmacist to confirm which form you have.

Mild stomach upset or nausea is common when first starting this medicine. Taking the capsule form with a meal can help reduce these side effects. If your stomach issues are severe or do not go away, talk to your doctor.

Antacids and other acid reducers can stop your body from absorbing Itrafab-200 Capsule capsules. You should take antacids at least 2 hours after taking this medicine, or take the capsules with an acidic beverage like cola. Talk to your pharmacist for specific advice.

Watch for warning signs of liver damage, including yellowing of your skin or eyes, unusually dark urine, pale stools, severe nausea, vomiting, or extreme fatigue. If you notice any of these symptoms, stop taking the medicine and call your doctor right away.

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Country of origin

India

Manufacturer/Marketer address

Kailash Industrial Complex, D-41, Vikhroli West, Mumbai, Maharashtra 400079
Other Info - ITR0548
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