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  3. Ivacran 5 Tablet

Ivacran 5 Tablet, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Ivacran 5 Tablet is used to treat heart failure and angina pain. It contains Ivabradine, which works by slowing the heart rate so the heart can pump more blood through the body each time it beats. This medicine may cause side effects such as feeling tired, irregular or rapid heartbeat, headache, dizziness, visual impairment or blurry vision. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

IVABRADINE-5MG

Manufacturer/Marketer :

Elder Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Ivacran 5 Tablet

Ivacran 5 Tablet is used to treat heart failure and symptomatic stable angina pectoris (chest pain or discomfort). It lowers the risk of worsening heart conditions that may require hospitalisation.

Ivacran 5 Tablet contains Ivabradine, which works by slowing the heart rate, allowing the heart to pump more blood through the body with each beat. Thereby, Ivacran 5 Tablet improves heart functioning and reduces the number of angina attacks.

The possible side effects of Ivacran 5 Tablet are vision problems, nausea, abdominal pain, diarrhoea, and headache. Most of these side effects may not need medical attention. However, if the side effects persist or worsen, consult your doctor.

Do not take Ivacran 5 Tablet if you are allergic to any of its components. Ivacran 5 Tablet is not recommended during pregnancy and breastfeeding. Keep your doctor informed about your health condition and all the medicines you are taking to rule out any potential interactions.

Uses of Ivacran 5 Tablet

Ivacran 5 Tablet is used in the treatment of angina and chronic heart failure. The detailed uses of Ivacran 5 Tablet are as follows:

  • Treatment of Chronic Heart Failure: Ivacran 5 Tablet treats chronic heart failure by reducing heart rate, improving heart function, and decreasing the risk of hospitalisation and cardiovascular events.
  • Treatment of Angina: Ivacran 5 Tablet is used to treat angina by reducing the frequency of chest pain, improving exercise tolerance by lowering heart rate, and decreasing the severity of symptoms.

Directions for Use

  • Ivacran 5 Tablet should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Ivacran 5 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Ivacran 5 Tablet is used for the treatment of heart failure and angina. It contains Ivabradine, a heart-rate-lowering medicine known as a hyperpolarisation-activated cyclic nucleotide-gated (HCN) channel blocker.
  • It helps lower the risk of hospitalisation due to worsening heart failure. It works by slowing the heart rate, which reduces the heart's workload and improves cardiac efficiency.
  • Ivacran 5 Tablet helps relieve chest pain (angina) caused by insufficient blood flow to the heart.
  • It is used in patients who cannot tolerate beta-blockers or have inadequate symptom control even while on beta-blocker therapy (used in combination).
  • It is given along with standard heart failure therapy, including beta-blockers, or as an alternative when beta-blockers are not suitable.

How Ivacran 5 Tablet Works

Ivacran 5 Tablet contains Ivabradine, which works by slowing the heart rate, allowing the heart to pump more blood through the body with each beat. Thereby, Ivacran 5 Tablet improves heart functioning and reduces the number of angina attacks.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ivacran 5 Tablet
  • Manage stress with relaxation techniques to avoid eye-straining.
  • Establish a consistent sleep schedule.
  • Practice good eye care, including proper hygiene and protection from excessive strain.
  • Protect your eyes from harsh light by wearing shades when necessary.
  • Eat foods like leafy greens, citrus fruits, berries, nuts, fatty fish, sweet potatoes, avocados, and eggs to support eye health.
  • Consult an eye specialist if symptoms persist.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Limit or avoid intake of stimulants like tobacco, caffeine and alcohol.
  • Drink sufficient water to maintain electrolyte balance.
  • Regularly do aerobic exercises.
  • Practice relaxation techniques such as meditation, or deep breathing to reduce stress.
  • Some medicines may be advised by your doctor such as beta-blockers or calcium channel blockers based on your condition.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.

What if I have taken an overdose of Ivacran 5 Tablet

Do not take more than the prescribed dose of Ivacran 5 Tablet as it may cause an overdose. The symptoms of overdose include a very slow heartbeat, dizziness, excessive tiredness, and lack of energy. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Ivacran 5 Tablet if you are allergic to any of its components, if you have very low blood pressure, or certain heart conditions (sick sinus syndrome, sinoatrial block, or 3rd degree atrioventricular block).
  • Inform your doctor if you have/had liver or kidney problems, slow heart rate, heart rhythm problems, heart conduction problems, or stroke.
  • Ivacran 5 Tablet is not recommended during pregnancy as it may harm the unborn baby. Tell your doctor right away if you become pregnant during treatment with Ivacran 5 Tablet.
  • Consult your doctor if you are breastfeeding. Your doctor will decide if you will take Ivacran 5 Tablet or breastfeed.
  • Ivacran 5 Tablet may increase the risk of irregular or rapid heartbeat. Tell your doctor if you notice symptoms of an irregular or rapid heartbeat, such as palpitations, chest pressure, near-fainting, fainting, or worsened shortness of breath.
  • This medicine can also cause bradycardia (a slower-than-normal heart rate). Tell your doctor if you have a slowing of your heart rate or any symptoms of a slow heart rate, such as dizziness, fatigue, or lack of energy.

Drug-Drug Interactions

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IvabradineKetoconazole
Critical
IvabradineCeritinib
Critical

Drug-Drug Interactions

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IvabradineKetoconazole
Critical
How does the drug interact with Ivacran 5 Tablet:
Coadministration of Ivacran 5 Tablet with Ketoconazole can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ivacran 5 Tablet with Ketoconazole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IvabradineCeritinib
Critical
How does the drug interact with Ivacran 5 Tablet:
Coadministration of Ivacran 5 Tablet with ceritinib can increase the levels and effects of Ivacran 5 Tablet.

How to manage the interaction:
Taking Ivacran 5 Tablet with Ceritinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
IvabradineVoriconazole
Critical
How does the drug interact with Ivacran 5 Tablet:
Using Ivacran 5 Tablet together with voriconazole may significantly increase the blood levels and effects of Ivacran 5 Tablet.

How to manage the interaction:
Taking Ivacran 5 Tablet with Voriconazole together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
IvabradineImatinib
Critical
How does the drug interact with Ivacran 5 Tablet:
Coadministration of Ivacran 5 Tablet with Imatinib can increase the levels of Ivacran 5 Tablet in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Ivacran 5 Tablet with Bosutinib together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
IvabradinePosaconazole
Critical
How does the drug interact with Ivacran 5 Tablet:
Using Ivacran 5 Tablet together with posaconazole may significantly increase the blood levels and effects of Ivacran 5 Tablet.

How to manage the interaction:
Taking Ivacran 5 Tablet with Posaconazole together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
IvabradineDoxepin
Severe
How does the drug interact with Ivacran 5 Tablet:
Coadministration of Ivacran 5 Tablet with Doxepin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Ivacran 5 Tablet with Doxepin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IvabradinePrimidone
Severe
How does the drug interact with Ivacran 5 Tablet:
Coadministration of Ivacran 5 Tablet with primidone can reduce the blood levels of Ivacran 5 Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Ivacran 5 Tablet with Primidone together can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IvabradineGranisetron
Severe
How does the drug interact with Ivacran 5 Tablet:
Coadministration of Ivacran 5 Tablet with Granisetron can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ivacran 5 Tablet with Granisetron together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
IvabradineIdarubicin
Severe
How does the drug interact with Ivacran 5 Tablet:
Taking Idarubicin and Ivacran 5 Tablet together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Idarubicin and Ivacran 5 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
IvabradineCiprofloxacin
Severe
How does the drug interact with Ivacran 5 Tablet:
Coadministration of ciprofloxacin and Ivacran 5 Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking ciprofloxacin and Ivacran 5 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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IVABRADINE-5MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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IVABRADINE-5MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
grapefruit juice can significantly increase the blood levels and effects of Ivacran 5 Tablet, which may result in excessive slowing of heart rate or other conduction disturbances. Avoid or limit the consumption of grapefruit or grapefruit juice while taking Ivacran 5 Tablet therapy, this may result in an interaction and increase the levels of Ivacran 5 Tablet. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

  • Follow a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Ivacran 5 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

A person taking Ivacran 5 Tablet is not allowed to consume alcohol as alcohol may worsen the dizziness.

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Pregnancy

Unsafe

Do not take Ivacran 5 Tablet if you are pregnant or are planning to have a baby. If you are pregnant and have taken Ivabradine, talk to your doctor. Do not take Ivacran 5 Tablet if you are able to become pregnant unless you use reliable contraceptive measures.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Ivacran 5 Tablet. Please consult your doctor if you are a lactating mother.

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Driving

Caution

Be careful when driving or operating machinery where sudden changes in light can happen, especially when driving at night.

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Liver

Unsafe

Ivacran 5 Tablet is not recommended for patients with severe preexisting liver disease. However, this medication is only used in patients with liver disease if prescribed by the doctor.

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Kidney

Unsafe

Take Ivacran 5 Tablet is not recommended for use in patients dealing with severe renal disease. Ivacran 5 Tablet does not interfere with the functions of kidneys in cardiac heart failure patients, but still, this medicine can only be used after the doctor's recommendation.

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Children

Caution

Please consult your doctor if you have any concerns regarding the usage of Ivacran 5 Tablet in children.

Have a query?

FAQs

Ivacran 5 Tablet is used to treat symptomatic stable angina pectoris and chronic heart failure.

Ivacran 5 Tablet contains Ivabradine, which works by reducing the heart rate by a few beats per minute. In this way, it lowers the heart's requirement for oxygen, especially in situations where an angina attack can happen. This helps control or reduce the chances of more angina attacks.

Yes, a woman should always take every measure, including a birth control pill, to prevent pregnancy while taking Ivacran 5 Tablet as this medicine can harm an unborn baby.

No, Ivacran 5 Tablet should not be used in those who are suffering from cardiogenic shock (a potentially fatal condition in which your heart suddenly cannot pump enough blood to fulfil your body's needs).

Reducing the heart rate is required in patients dealing with angina and heart failure. When the heart rate gets reduced, the heart can pump more blood into the whole body without affecting the heart's contraction and relaxation.

Do not stop taking Ivacran 5 Tablet on your own. After checking the heart activity, the doctor may reduce the dose before directly stopping the drug. A balanced diet, rest, and exercise are essential for maintaining good heart health, so the doctor may also recommend these lifestyle changes before discontinuing the medication directly.

Yes, a person taking Ivacran 5 Tablet needs to be under strict doctor's guidance. Monitoring the heart rate before the treatment and during the treatment is done to check the effects of the medicine. The monitoring of the heart is done with the help of an ECG.

No, usage of Ivacran 5 Tablet is prohibited in persons dealing with sick sinus syndrome, significant hypotension, or third-degree AV block. If you have any concerns regarding this, please discuss them with your doctor.

No, if a person is prescribed to take Ivacran 5 Tablet, they are strictly restricted from consuming grapefruit juice as it may worsen their side effects.

Ivacran 5 Tablet is a heart medicine (hyperpolarization-activated cyclic nucleotide-gated channel blocker) used to treat angina and heart failure.

Ivacran 5 Tablet may cause blurred/cloudy vision, double vision and impaired vision. Avoid driving, operating machinery or doing any activities that require proper vision until you know how this medicine affects you.

Overdose of Ivacran 5 Tablet may cause severe and prolonged bradycardia (slow heart rate), dizziness, lack of energy and excessive tiredness. Contact the doctor immediately if you experience these symptoms or if you have overdosed on Ivacran 5 Tablet.

Ivacran 5 Tablet may cause foetal toxicity. So, females of reproductive potential must use effective contraception whilst on treatment with Ivacran 5 Tablet. Regular monitoring of heart rhythm and heart rate is recommended.

Ivacran 5 Tablet does not lower blood pressure. It should not be used if you have very low blood pressure.

Ivacran 5 Tablet is not a beta-blocker. It belongs to the class of medications called hyperpolarisation-activated cyclic nucleotide-gated (HCN) channel blockers. It helps the heart pump more blood through the body by slowing the heart rate.

Side effects of Ivacran 5 Tablet include tiredness, irregular or rapid heartbeat, headache, dizziness, visual impairment or blurry vision. Consult the doctor if any of the side effects bother you.

Country of origin

India
Other Info - IV20692

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 8, 2025 | 11:15 AM IST

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Reference

  1. https://www.drugs.com/ppa/.html
  2. https://www.medicines.org.uk/emc/files/pil.9269.pdf
  3. https://www.webmd.com/drugs/2/drug-159226/ivabradine-oral/details
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