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  3. Jaknat 10 Tablet 10's

Jaknat 10 Tablet 10's, Pack of 10 TabletS
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Composition :

TOFACITINIB-10MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Jaknat 10 Tablet

Jaknat 10 Tablet is used to treat rheumatoid arthritis (an autoimmune disease which leads to joint pain and damage), psoriatic arthritis (an inflammatory condition of the joints), and ulcerative colitis (an inflammatory disease of the large intestine).

Jaknat 10 Tablet contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 

Not everyone who is taking Jaknat 10 Tablet will get these side effects. In some cases, you may experience common side effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

You can take Jaknat 10 Tablet with or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.

Avoid taking Jaknat 10 Tablet if you are allergic to it. Inform your doctor if you have an active infection, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Jaknat 10 Tablet if you are pregnant or breastfeeding. Jaknat 10 Tablet is not recommended for use in children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Jaknat 10 Tablet

'Jaknat 10 Tablet is used in the treatment of Rheumatoid arthritis, Psoriatic arthritis, and Ulcerative colitis. The detailed uses of Jaknat 10 Tablet are as follows:<br/> • Treatment of Rheumatoid Arthritis: Jaknat 10 Tablet helps to manage moderate to severe rheumatoid arthritis by reducing joint pain, inflammation, and slowing disease progression.<br/> • Management of Psoriatic Arthritis: Jaknat 10 Tablet treats active psoriatic arthritis by reducing joint pain, swelling, stiffness, and improving overall joint function.<br/> • Treatment of Ulcerative Colitis: Jaknat 10 Tablet helps to induce and maintain remission in moderate to severe ulcerative colitis.<br/>'

Directions for Use

• Jaknat 10 Tablet can be taken with or without food. • It is recommended to take Jaknat 10 Tablet 1-2 times a day, depending on your medical condition, or as prescribed by your doctor. • Swallow Jaknat 10 Tablet as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

Jaknat 10 Tablet belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. 

Jaknat 10 Tablet is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).

How Jaknat 10 Tablet Works

Jaknat 10 Tablet contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Jaknat 10 Tablet

Take Jaknat 10 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Jaknat 10 Tablet if you are allergic to any of its components; if you have a severe infection, bloodstream infection, or if you have severe liver problems such as cirrhosis. 
  • Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, chronic lung disease, liver problems, hepatitis B/C, cancer, inflammation/ulcers of the large intestine, or kidney problems; are planning to get vaccinated; or have heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems. 
  • If your white blood cell count or red blood cell count is low, avoid taking Jaknat 10 Tablet .
  • Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties. Inform your doctor about your complete medical and medication history before starting treatment with Jaknat 10 Tablet , which helps the physician decide the best treatment plan.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIRHEUMATICS, DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDs)

Jaknat 10 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known if alcohol interacts with Jaknat 10 Tablet , so please consult a doctor.

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Pregnancy

Unsafe

Jaknat 10 Tablet must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Jaknat 10 Tablet and for 4 weeks after discontinuation.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Jaknat 10 Tablet . Please consult a doctor if you have any concerns.

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Driving

Safe

Jaknat 10 Tablet generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Jaknat 10 Tablet is not recommended for patients with severe liver problems.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Jaknat 10 Tablet is not recommended for children below 18 years as safety and effectiveness were not established.

Have a query?

FAQs

Jaknat 10 Tablet is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

Jaknat 10 Tablet works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

Hypertension/high blood pressure could be a side-effect of Jaknat 10 Tablet . Consult your doctor before taking Jaknat 10 Tablet if you have high blood pressure or if you are taking anti-hypertensive medicines.

Diarrhoea might be a side-effect of Jaknat 10 Tablet . Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Jaknat 10 Tablet might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting Jaknat 10 Tablet if you are trying to become pregnant or if you have any concerns regarding this.

Jaknat 10 Tablet affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.

Jaknat 10 Tablet is not recommended for patients with severe liver impairment. Dose adjustment may be needed in patients with mild to moderate liver impairment. Please consult the doctor if you have liver problems.

Jaknat 10 Tablet may increase the risk of cancer by changing the way the immune system works. Inform the doctor if you ever had any type of cancer.

Jaknat 10 Tablet may begin working within 2-8 weeks after starting the treatment.

Jaknat 10 Tablet should not be taken along with tocilizumab as it might increase the risk of infections. Before starting Jaknat 10 Tablet , inform the doctor if you are taking tocilizumab.

Prior to starting Jaknat 10 Tablet , active or latent tuberculosis test, CBC (complete blood count), LFT (liver function test), and lipid profile tests should be done.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - JAK0027

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 11:28 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.2500.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/203214s018lbl.pdf
  3. https://www.drugs.com/mtm/tofacitinib.html
  4. https://www.ema.europa.eu/en/documents/product-information/xeljanz-epar-product-information_en.pdf

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