Janumet XR CP Combipack is a combination drug used in the treatment of type 2 diabetes mellitus. Type 2 diabetes develops when the body does not produce enough insulin or when the body's insulin does not work as well as it should. It can also develop if the body produces too much glucagon. Insulin is a substance which helps to lower the level of sugar in your blood, especially after meals.

Janumet XR CP Combipack contains metformin and vildagliptin, which help control blood sugar levels. It works by causing the pancreas to produce more insulin and less glucagon (the effect of vildagliptin) and also by helping the body utilise insulin more effectively (the effect of metformin).

Not everyone who is taking Janumet XR CP Combipack will get these side effects. The most common side effect of Janumet XR CP Combipack is hypoglycemia (low blood glucose levels) characterised by dizziness, sweating, hunger pangs, dry mouth and skin, etc. Other side effects include changes in taste, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

Janumet XR CP Combipack should be taken with food to avoid an upset stomach. It is advised to take it at the same time each day for best results. For better advice, your doctor will determine the appropriate dose, which can change quickly depending on your condition. Do not skip your meals, and also carry a form of sugar with you to prevent low blood sugar levels.

Avoid taking Janumet XR CP Combipack if you are allergic to it. Janumet XR CP Combipack should not be stopped even if you feel better without consulting your doctor, as sugar levels may change. If you stop taking Janumet XR CP Combipack abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney damage and nerve damage. Janumet XR CP Combipack should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease or are planning to get pregnant or breastfeed. You must continue following the diet and exercise recommended for you while on treatment with Janumet XR CP Combipack.

• Janumet XR CP Combipack should be taken with meals to avoid stomach upset. • It is usually taken twice daily; however, your doctor may adjust the dosage based on your blood sugar levels. • Swallow Janumet XR CP Combipack as a whole with a glass of water. • Do not crush, chew, or break it.

• Janumet XR CP Combipack helps your pancreas produce more insulin, effectively utilise insulin, and decrease the excess sugar that your liver makes.
• It helps control the rise of blood sugar levels in your body after a meal. 
• Janumet XR CP Combipack plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.

• Inform your doctor if you are allergic to Janumet XR CP Combipack.
• This medicine should not be used in patients with type 1 diabetes or with diabetic ketoacidosis.
• Some diabetic patients, while taking Janumet XR CP Combipack, might develop a rare but serious condition called lactic acidosis (too much lactic acid accumulated in the blood) that can damage the working of your liver and kidneys, which are required for the elimination of excess lactic acid from the blood.
• Before you start taking Janumet XR CP Combipack, tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, or a low vitamin B12 level.
• Janumet XR CP Combipack, when used with insulin, may significantly lower the blood sugar level, leading to a hypoglycemic condition, which can be fatal.
• Inform your doctor if you are pregnant, planning for a pregnancy or breastfeeding before starting the treatment.
• Prolonged intake of Janumet XR CP Combipack may lower your thyroid-stimulating hormone (TSH); hence, an annual checkup of TSH is recommended.
• In rare cases, you may also develop a severe skin reaction known as bullous pemphigoid that requires immediate medical attention.
• Inform your doctor if you are scheduled to undergo a diagnostic test that involves an injection of dye or an X-ray contrast agent. The use of Janumet XR CP Combipack should be stopped for a short time before having an X-ray procedure.
• It is always important to check for the expiry of the medicine. Discard the medicine if it reaches the expiry date.