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  3. Jolclo 500 mg Injection 1's

Jolclo 500 mg Injection 1's, Pack of 1 INJECTION
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Written By Thota sri Harshini ,
Reviewed By Santoshini Reddy G , M Pharmacy

Jolclo 500 mg Injection is an antibiotic medicine used to treat bacterial infections. It contains cloxacillin, which works by inhibiting the formation of the bacterial cell wall (a protective covering) and stopping the growth of bacteria. In some cases, Jolclo 500 mg Injection may cause side effects like discomfort and soft stools. Let the doctor know if you are taking any other medicines or have any medical conditions.

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Synonym :

CLOXACILLIN SODIUM

Composition :

CLOXACILLIN-500MG

Manufacturer/Marketer :

Jolly Healthcare

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Jolclo 500 mg Injection

Jolclo 500 mg Injection is an antibiotic medicine used to treat bacterial infections. A bacterial infection occurs when harmful bacteria enter and grow in the body. This bacteria can infect any part of the body and multiply very quickly. Jolclo 500 mg Injection is effective in treating infections caused by bacteria only and does not treat viral infections like flu or a common cold.

Jolclo 500 mg Injection contains Cloxacillin, a penicillinase-resistant penicillin which works by inhibiting the formation of the bacterial cell wall (a protective covering). This eventually leads to the death of the bacterial cell and thus prevents the growth of bacteria. Thereby, Jolclo 500 mg Injection helps treat bacterial infection.

Jolclo 500 mg Injection may cause certain side effects in some individuals, such as nausea, diarrhoea or soft stool, stomach upset, vomiting, headache, inflammation at the site of administration, and malaise (discomfort). These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Jolclo 500 mg Injection should be avoided if you are allergic to any of its components. Before starting the treatment, inform your doctor if you have liver/kidney problems, blood-brain barrier defects and neurological defects like seizures. Keep the doctor informed about your health condition, including the current medications and medical history. Consult the doctor if you are pregnant or breastfeeding before starting treatment with Jolclo 500 mg Injection.

Uses of Jolclo 500 mg Injection

Jolclo 500 mg Injection is used to treat bacterial infections. The detailed uses of Jolclo 500 mg Injection are as follows:<br/>• Treatment of Bacterial Infections: Jolclo 500 mg Injection is used for skin infections, pneumonia, sinusitis, osteomyelitis, endocarditis, and blood infections.<br/>• Penicillin-resistant staphylococcal infections: Jolclo 500 mg Injection is effective against penicillin-resistant staphylococcal infections.<br/>

Have a query?

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Jolclo 500 mg Injection will be administered by the doctor or nurse in a healthcare setting.• Do not self-administer.

Medicinal Benefits

Jolclo 500 mg Injection is used to treat bacterial infections like skin and soft tissue infections, endocarditis (inflammation inside the heart chambers or valves), abscesses (buildup of pus), osteomyelitis (inflammation or swelling in the bones), and sepsis (extreme reaction to an infection). It contains cloxacillin, a broad-spectrum penicillinase-resistant penicillin antibiotic that acts against both aerobic (growing in the presence of oxygen) and anaerobic (growing in the absence of oxygen) bacteria. Jolclo 500 mg Injection works by inhibiting the bacterial cell wall formation (a protective covering). This eventually leads to the death of the bacterial cell and thus prevents the growth of bacteria. Thereby, Jolclo 500 mg Injection helps treat bacterial infection.

How Jolclo 500 mg Injection Works

Jolclo 500 mg Injection works by inhibiting the formation of the bacterial cell wall (a protective covering). This eventually leads to the death of the bacterial cell and thus prevents the growth of bacteria. Thereby, Jolclo 500 mg Injection helps treat bacterial infection.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Jolclo 500 mg Injection out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Jolclo 500 mg Injection

Overdose of Jolclo 500 mg Injection may cause malaise, vomiting, diarrhoea, change in electrolyte concentration, coma, muscle fasciculations, myoclonia, cramps, hemolytic reaction, kidney insufficiency, and acidosis. As Jolclo 500 mg Injection is a parenteral formulation which will be administered by experienced medical staff, the chance of overdose may be less. Your doctor may initiate an immediate necessary measure if an overdose is suspected.

Drug Warnings

Jolclo 500 mg Injection should be avoided if you are allergic to any of its components. Before starting the treatment, inform your doctor if you have liver/kidney problems, blood-brain barrier defects, or neurological defects like seizures. Consult your doctor if you are pregnant or breastfeeding before starting treatment with Jolclo 500 mg Injection. Keep the doctor informed about your health condition, including the current medications and medical history.

Drug-Drug Interactions

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CloxacillinMethotrexate
Severe

Drug-Drug Interactions

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CloxacillinMethotrexate
Severe
How does the drug interact with Jolclo 500 mg Injection:
Co-administration of methotrexate with Jolclo 500 mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Jolclo 500 mg Injection and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, Consult a doctor. Do not stop using any medications without consulting to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Taking probiotics after receiving Jolclo 500 mg Injection may help with diarrhoea.
  • Drink plenty of fluids to avoid an upset stomach and hydrate your body.
  • Avoid intake of alcoholic beverages as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the medicine in fighting off infections.
  • Maintain good hygiene and avoid contaminated or processed food.
  • Include more fibre-enriched food like whole-grain bread and brown rice in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

It is unknown whether alcohol interacts with Jolclo 500 mg Injection. However, it is best to avoid or limit alcohol consumption to avoid any negative complications.

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Pregnancy

Caution

Jolclo 500 mg Injection is considered safe in pregnancy. However, inform your doctor if you are pregnant or planning to become pregnant before receiving Jolclo 500 mg Injection.

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Breast Feeding

Safe

Jolclo 500 mg Injection passes into breastmilk in minimum quantities that cause no risk to your infant. However, if you are breastfeeding, inform your doctor before receiving Jolclo 500 mg Injection.

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Driving

Safe

Jolclo 500 mg Injection may not affect your ability to drive a car or to use machines. However, drive or operate machinery only if you are alert.

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Liver

Caution

If you have an existing or a history of liver disease, inform your doctor before receiving Jolclo 500 mg Injection. Based on your condition, your doctor may adjust the dose of this medicine or prescribe a suitable alternative.

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before receiving Jolclo 500 mg Injection. Your doctor may initiate treatment with low doses, but prolonged treatment may worsen your condition.

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Children

Consult your doctor

The safety and efficacy of Jolclo 500 mg Injection have not been established in children aged less than one year. Your doctor may prescribe this medicine if required based on your child's age, body weight and condition.

FAQs

Jolclo 500 mg Injection is used to treat bacterial infections, including skin and soft tissue infections, endocarditis (inflammation inside the heart chambers or valves), abscesses, osteomyelitis (inflammation or swelling of the bones), and sepsis.

Jolclo 500 mg Injection contains cloxacillin, which works by inhibiting the formation of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and helps treat bacterial infection.

No, Jolclo 500 mg Injection is not used to treat viral infections. It is an antibiotic used to treat bacterial infections only.

Consult the doctor if you do not feel better even after using Jolclo 500 mg Injection or if your condition worsens during treatment with Jolclo 500 mg Injection.

Jolclo 500 mg Injection may cause side effects such as nausea, diarrhoea or soft stool, stomach upset, vomiting, headache, inflammation at the site of administration, and malaise. These side effects do not require medical attention and gradually resolve over time. However, if they persist or worsen, please consult your doctor.

Yes, Jolclo 500 mg Injection may decrease the effect of oral contraceptive pills and might lead to unplanned pregnancy. It is better to discuss with your doctor for alternative methods to prevent pregnancy.

Country of origin

India

Manufacturer/Marketer address

D-50, Basement, Shanti Path, Jawahar Nagar,Jaipur, Rajasthan, India(302004)
Other Info - JOL0073

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Author Details

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 9:21 AM IST

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Reference

  1. https://http://www.efda.gov.et/wp-content/uploads/2023/09/Cloxacillin-Sodium-for-injection_North-China-Pharmaceutical-Co.-Ltd.pdf
  2. https://pubchem.ncbi.nlm.nih.gov/compound/Cloxacillin#section=Effects-During-Pregnancy-and-Lactation
  3. https://go.drugbank.com/drugs/DB01147
  4. https://verification.fda.gov.ph/files/DRP-981_PI_01.pdf

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